Annales de medecine interne最新文献

Annales de medecine interne Pub Date : 2006-01-01 DOI: 10.1016/S1634-6939(06)75427-8

J. Pouchot, P. Vinceneux

引用次数: 0

[Lymphoma genesis in the context of HIV infection]. [HIV感染背景下的淋巴瘤发生]。

Annales de medecine interne Pub Date : 2003-12-01

Caroline Besson, Martine Raphaël

{"title":"[Lymphoma genesis in the context of HIV infection].","authors":"Caroline Besson, Martine Raphaël","doi":"","DOIUrl":"","url":null,"abstract":"The incidence of lymphomas is high among HIV infected patients. These lymphomas are non-Hodgkin's lymphoma (NHL) in 70% of cases and Hodgkin's disease (HD) in 30% of cases. Their localization is often extra-nodal with early dissemination. B-cell high grade NHL predominates. The most frequent histological types are diffuse large B-cell lymphoma (30 to 40%) and Burkitt's lymphoma (40 to 50%). Other histological types are low-grade B-cell lymphoma, polymorphic B cell lymphoma and primary effusion lymphoma. Three main factors are predominant in HIV-related lymphomagenesis: cellular immunodeficiency, oncogene viruses (Epstein-Barr and HHV8) and molecular lesions. HIV-related cellular immunodeficiency leads to the increase of EBV infected B-cells and to the diminution of antitumor immunity. Clonal EBV genome is found in lymphoma cells in 30 to 70% of cases of HIV-related NHL. It expresses oncogenic proteins including LMP-1 which behaves like an activated CD40. It induces the expression of intra-cellular genes which stimulate cell growth and inhibit apoptosis. Cytogenetic and molecular lesions are not specific to HIV-related NHL or to histological subtypes. A better knowledge of these mechanisms should lead to the development of specific targeted treatments (antiviral, cytotoxic anti-EBV lymphocytes, cell cycle regulators).","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"154 8","pages":"523-8"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40856121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Necrolytic migratory erythema revealing glucagonoma without diabetes]. [坏死性迁移性红斑显示胰高血糖素瘤，无糖尿病]。

Annales de medecine interne Pub Date : 2003-12-01

Cécile Marty, Antoine Bennet, Paule Bayle, Marie Danjoux, Thibaud Lalande, Marie-Claude Marguery, Jacques Bazex

引用次数: 0

[Bilateral primary non-Hodgkin's lymphomas of the adrenals]. [双侧原发性肾上腺非霍奇金淋巴瘤]。

Annales de medecine interne Pub Date : 2003-12-01

Lamia Rezgui-Marhoul, Kamel Bouslama, Mohamed Bouchriha, Ali Harmel, Sabah Mzabi-Rgaya, Lotfi Hendaoui, Mohamed Ben Dridi

引用次数: 0

[A survey of pain prevalence at Albert-Chenevier Hospital. Comparison of patient, caregivers and physician assessments]. 阿尔伯特-舍内维尔医院疼痛患病率调查。患者、护理人员和医生评估的比较]。

Annales de medecine interne Pub Date : 2003-12-01

Valérie Jeanfaivre, Catherine Diviné, Marie-Noëlle Akalin, Françoise Anacharsis, Annie Montagne, Jean-Claude Le Parco

{"title":"[A survey of pain prevalence at Albert-Chenevier Hospital. Comparison of patient, caregivers and physician assessments].","authors":"Valérie Jeanfaivre, Catherine Diviné, Marie-Noëlle Akalin, Françoise Anacharsis, Annie Montagne, Jean-Claude Le Parco","doi":"","DOIUrl":"","url":null,"abstract":"The purpose of this study is to estimate the prevalence of pain in hospitalized patients and to compare pain assessments performed by patients, caregivers and physicians. This cross-sectional study was based on evaluating pain with three questionnaires. Two structured questionnaires explored the patient's and physician's points of view about hospital pain management. Caregivers used the validated Doloplus-2 scale. The three assessments were considered consistent when all three indicated the presence or absence of pain. All inpatients (447) were included. The prevalence of pain was 57% when assessment was performed by caregivers and 53% when it was performed by physicians. Among patients included in the prevalence study, 366 could express themselves and agreed to answer the self-assessment questionnaire (82%): 66% of these patients reported pain. Patients and physicians often reported leg pain. Assessment of pain produced a higher level of pain intensity when performed by patients than when by physicians. Furthermore, 88% of patients reporting pain received pain relief treatment: nevertheless patients felt that their pain was satisfactorily managed in only half of their locations, and they had a less positive appreciation of their level of pain management than physicians did. Our study showed that many psychiatric patients declared they suffered pain. Full consistency between the three assessments was noted for half the cases. One out of ten patients experiencing pain was not identified.","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"154 8","pages":"499-508"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40933854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Investigation of the complement system in clinical practice]. 临床实践中补体系统的研究

Annales de medecine interne Pub Date : 2003-12-01

Véronique Frémeaux-Bacchi, Marie-Agnès Dragon-Durey, Jacques Blouin, Luc Mouthon, Wolf Herman Fridman

引用次数: 0

[Meteorologic conditions and esophageal varices rupture]. [气象条件与食管静脉曲张破裂]。

Annales de medecine interne Pub Date : 2003-12-01

Nabil Tahri, Ali Amouri, Habib Fekih, Faïçal El-Euch, Mohamed Salah Krichen

{"title":"[Meteorologic conditions and esophageal varices rupture].","authors":"Nabil Tahri, Ali Amouri, Habib Fekih, Faïçal El-Euch, Mohamed Salah Krichen","doi":"","DOIUrl":"","url":null,"abstract":"Background: While meteorologic conditions are thought to be related to the incidence of certain cardiac and cerebrovascular events, very little information is available concerning the onset of variceal bleeding. We undertook this study to determine whether there is any correlation between esophageal variceal hemorrhage and several meteorologic and astronomic parameters.Methods: Sixty-seven episodes of bleeding from ruptured esophageal varices observed in 52 patients from southern Tunisia during a 7-Year period were studied retrospectively. All patients underwent endoscopic examination within 24 hours of admission. The date of the event (variceal rupture) was considered--if no stigmates of active bleeding were found at endoscopy--as the day of occurrence of the hematemesis and the day preceding melena. Meteorologic readings (11 parameters) plus moon-cycle, circadian and seasonal distribution of the 67 days of variceal bleeding in comparison with a control period of days randomly selected among 134 days without rupture.Results: No relationship was found between variceal bleeding and mean atmospheric pressure, daily hours of sunshine, nebulosity, direction and velocity of wind and mean humidity. On the contrary, a significant correlation was observed with the mean temperature (18 degrees C vs 21.16 degrees C; p=0003), rainfall (p<0.01) and stormy weather (p=0.008), the latter being the only parameter retained as an independent factor at multivariate analysis: OR=13.37 (95% CI=1.5-118.5). Furthermore, a negative correlation was found with full moon but only at univariate analysis (p=0.04). The seasonal distribution of variceal bleeding episodes showed the highest percentage during winter with a significant variation at multivariate analysis: OR=3.2 (95% IC=1.6-6.54). Occurrence of variceal bleeding also showed a circadian variation with the higher prevalence night between 6 and 0 PM (p<0.001).","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"154 8","pages":"509-14"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40856119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Chronic fever revealing an urachal cyst]. 慢性发热，显露尿管囊肿。

Annales de medecine interne Pub Date : 2003-12-01

Thierry Weitten, Maher Ben Abdelgheni, Serge Rohr, Fazel Boujan, Jean-Frédéric Blicklé, Emmanuel Andrès

引用次数: 0

Inflammatory pseudotumor of lymph nodes. 淋巴结炎性假瘤。

Annales de medecine interne Pub Date : 2003-12-01

Marco Trevenzoli, Anna Maria Cattelan, Massimiliano Lanzafame, Lolita Sasset, Ercole Concia, Sandro Vento

引用次数: 0

[Progress in the management of pyogenic cerebral abscesses in non-immunocompromised patients]. [非免疫功能低下患者化脓性脑脓肿治疗进展]。

Annales de medecine interne Pub Date : 2003-12-01

Jérôme Tourret, Patrick Yeni

引用次数: 0