{"title":"The reliability of midstream urine culture from circumcised male infants.","authors":"J Amir, M Ginzburg, R Straussberg, I Varsano","doi":"10.1001/archpedi.1993.02160330059019","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160330059019","url":null,"abstract":"<p><p>The reliability of midstream urine culture from circumcised male infants was studied in 60 infants aged 1 to 21 weeks. A midstream urine specimen was collected after cleansing the penis. When the bladder was full again, a suprapubic bladder aspiration (SPA) was also performed. The results of the urine cultures were almost identical in specimens obtained midstream and by SPA. In 37 infants the cultures were sterile and in 13 positive, with the same microorganism being cultured in both instances. In one case, few colonies of Staphylococcus epidermidis grew only from the midstream culture. In nine infants, only midstream specimens were obtained because three attempts at SPA were unsuccessful. These results suggest that in circumcised male infants, the midstream method of obtaining urine for a culture is as reliable as SPA.</p>","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 9","pages":"969-70"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160330059019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19349830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hereditary angioedema: danazol therapy in a 5-year-old child.","authors":"A Barakat, A J Castaldo","doi":"10.1001/archpedi.1993.02160330021005","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160330021005","url":null,"abstract":"","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 9","pages":"931-2"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160330021005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19348598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The value of early treatment of deer tick bites for the prevention of Lyme disease.","authors":"F Agre, R Schwartz","doi":"10.1001/archpedi.1993.02160330035013","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160330035013","url":null,"abstract":"<p><strong>Objective: </strong>To determine if the early antibiotic treatment of deer tick bites prevented Lyme disease.</p><p><strong>Design: </strong>Prospective, double-blind, placebo-controlled, antibiotic treatment.</p><p><strong>Setting: </strong>Private practice in an area endemic for Lyme disease.</p><p><strong>Study participants: </strong>Patients between 3 and 19 years of age who received antibiotic treatment within 3 days following a deer tick bite.</p><p><strong>Interventions: </strong>Patients received an antibiotic or placebo and were followed up for stage I and II disease. All patients had blood drawn at the time of presentation and 6 weeks later for immunofluorescent antibodies (IFA).</p><p><strong>Measurements/main results: </strong>One patient in the placebo group developed clinical Lyme disease associated with an IFA titer of 1:32, considered weakly positive. Three other patients in the placebo group developed an IFA titer of 1:32; one had an influenzalike illness and two had no symptoms. None of the study patients developed any neurologic, cardiac, or arthritic symptoms in the 1- to 3-year follow-up.</p><p><strong>Conclusion: </strong>Based on the low frequency of illness, the absence of stage II disease, and the inability to establish the efficacy of early antibiotic treatment, we suggest that physicians not routinely use prophylactic antibiotics for deer tick bites.</p>","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 9","pages":"945-7"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160330035013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19349273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Granulomatous hepatitis in three children due to cat-scratch disease without peripheral adenopathy. An unrecognized cause of fever of unknown origin.","authors":"J J Malatack, R Jaffe","doi":"10.1001/archpedi.1993.02160330039014","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160330039014","url":null,"abstract":"<p><strong>Objective: </strong>To report the clinical experience of three patients with fever of unknown origin ultimately diagnosed as having cat-scratch granulomatous hepatitis in the absence of peripheral adenopathy.</p><p><strong>Design: </strong>Case-control study.</p><p><strong>Setting: </strong>Referral center at university-based referral practice.</p><p><strong>Patients: </strong>Three children with fever of unknown origin. Follow-up following presentation was 6 months for each patient.</p><p><strong>Measurement and results: </strong>All three patients with fever of unknown origin were diagnosed radiographically to have multiple hepatic defects. The defects were shown histologically to be granulomatous. Two of the three patients had Warthin-Starry staining bacilli in the granulomas consistent with a diagnosis of Afipia felis. All three had positive cat-scratch skin test results.</p><p><strong>Conclusions: </strong>Cat-scratch disease in the absence of peripheral adenopathy is a heretofore unrecognized cause of fever of undetermined origin and may account for a small, but significant, percentage of children presenting with it.</p>","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 9","pages":"949-53"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160330039014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19349274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acrodermatitis enteropathica-like syndrome secondary to isoleucine deficiency during treatment of maple syrup urine disease.","authors":"G P Giacoia, G T Berry","doi":"10.1001/archpedi.1993.02160330044015","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160330044015","url":null,"abstract":"<p><p>We describe a patient with maple syrup urine disease in whom an acrodermatitis enteropathica-like syndrome developed while he was receiving a branched-chain amino acid-free formula. Iatrogenically induced isoleucine deficiency developed and resulted in a decreased protein accretion and persistent increase in the plasma concentrations of leucine. A rapid clinical response to isoleucine supplementation was noted. This observation underscores the risks of using amino acid-free formulas without adequate supplementation of deficient amino acids.</p>","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 9","pages":"954-6"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160330044015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19349275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An updated pediatric perspective on the Apert syndrome.","authors":"M M Cohen, S Kreiborg","doi":"10.1001/archpedi.1993.02160330079025","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160330079025","url":null,"abstract":"<p><p>This review of the Apert syndrome, based on our research experience with 136 cases, provides a clinically relevant pediatric perspective. The brain is megalencephalic, resulting in a disproportionately high cranium and a mean birth length and weight above the 50th percentile. The growth pattern in childhood consists of a slowing of linear growth so that most values fall between the 5th and 50th percentiles. From adolescence to adulthood, slowing becomes more pronounced. Central nervous system abnormalities may occur in some cases, including malformations of the corpus callosum and limbic structures, gyral abnormalities, hypoplastic white matter, and heterotopic gray matter. Distortion ventriculomegaly is found because of the large brain in a misshapen skull. Progressive hydrocephalus is uncommon. Intelligence in patients with the Apert syndrome varies from normality to mental deficiency. Early release of the coronal suture and advancement and reshaping of the frontal bone reduce further dysmorphic and unwanted growth changes in the skull, but probably do not affect mentation. Associated cardiovascular and genitourinary anomalies occur in 10% and 9.6% of cases, respectively. Other important findings reviewed include upper- and lower-airway compromise, calvarial development, cervical vertebral anomalies, limb defects, ocular and otologic manifestations, and dermatologic characteristics.</p>","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 9","pages":"989-93"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160330079025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19349836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Kids are working.","authors":"E Feingold","doi":"10.1001/archpedi.1993.02160330019004","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160330019004","url":null,"abstract":"","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 9","pages":"929-31"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160330019004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19348597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Episodes of bradycardia during early infancy in the term-born and preterm infant.","authors":"J E Hodgman, T Hoppenbrouwers, L A Cabal","doi":"10.1001/archpedi.1993.02160330050017","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160330050017","url":null,"abstract":"<p><strong>Objective: </strong>To document the incidence of transient episodes of bradycardia in a group of healthy term and preterm infants during the first 1 to 6 months of life.</p><p><strong>Design: </strong>Longitudinal polysomnographic study.</p><p><strong>Setting: </strong>Sleep laboratory in a university-affiliated urban medical center.</p><p><strong>Participants: </strong>Fourteen healthy term-born infants, nine preterm infants with apnea in the nursery, and 10 preterm infants without apnea. Infants with neonatal morbidity except apnea were excluded.</p><p><strong>Measurements: </strong>Transient episodes of bradycardia (< or = 100 beats per minute) were identified in 2- to 4-hour early evening polysomnographic tracings. The relationship with apnea, transcutaneous oxygen levels, and sleep state was determined.</p><p><strong>Results: </strong>Transient episodes of bradycardia to 60 to 70 beats per minute were common, but there were no drops below 50 beats per minute. The incidence of transient episodes of bradycardia was inversely related to heart rate. Results for apneic and nonapneic premature infants were similar.</p><p><strong>Conclusions: </strong>Transient episodes of bradycardia are considered normal reflex responses and are not related to risk for sudden infant death syndrome. These results have implications for the setting of monitor alarms.</p>","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 9","pages":"960-4"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160330050017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19349277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathological case of the month. Meningioangiomatosis.","authors":"M M Drut, J M Miles, E Gilbert-Barness","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 9","pages":"1009-10"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19348592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New developments in the treatment of neutropenia.","authors":"I J Dunkel, J B Bussel","doi":"10.1001/archpedi.1993.02160330084026","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160330084026","url":null,"abstract":"","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 9","pages":"994-1000"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160330084026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18692969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}