American journal of diseases of children (1960)最新文献

{"title":"Autosomal recessive microcephaly, microcornea, congenital cataract, mental retardation, optic atrophy, and hypogenitalism. Micro syndrome.","authors":"M Warburg,&nbsp;O Sjö,&nbsp;H C Fledelius,&nbsp;S A Pedersen","doi":"10.1001/archpedi.1993.02160360051017","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160360051017","url":null,"abstract":"<p><p>Three affected children from an inbred family had microcornea, microcephaly, congenital cataract, severe mental retardation, retinal dystrophy, optic nerve atrophy, hypothalamic hypogenitalism, and agenesis of the corpus callosum. The disorder is presumably autosomal recessive; no identical syndrome has been described, but we consider syndromes with similar features.</p>","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 12","pages":"1309-12"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160360051017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19237906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonsteroidal anti-inflammatory drugs and gastrointestinal injury in children.","authors":"L L Barton","doi":"10.1001/archpedi.1993.02160360022006","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160360022006","url":null,"abstract":"","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 12","pages":"1280"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160360022006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19292185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Passive-active immunization in infants of hepatitis Be antigen-positive mothers. Comparison of the efficacy of early and delayed active immunization.","authors":"P M Grosheide,&nbsp;R del Canho,&nbsp;R A Heijtink,&nbsp;A S Nuijten,&nbsp;J Zwijnenberg,&nbsp;J R Bänffer,&nbsp;Y W Wladimiroff,&nbsp;M J Botman,&nbsp;J A Mazel,&nbsp;G C de Gast","doi":"10.1001/archpedi.1993.02160360058019","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160360058019","url":null,"abstract":"<p><strong>Objective: </strong>To assess the efficacy of late active immunization against hepatitis B concomitant with diphtheria, pertussis, tetanus, and polio vaccine in high-risk infants receiving hepatitis B immune globulin at birth.</p><p><strong>Design: </strong>Randomized study of infants born to mothers positive for hepatitis B surface antigen (HBsAg) and hepatitis Be antigen (HBeAg).</p><p><strong>Setting: </strong>Three large city hospitals and one rural area providing prenatal care and obstetric services.</p><p><strong>Subjects: </strong>Eighty neonates of HBsAg- and HBeAg-positive carrier mothers received 0.5 mL/kg of body weight hepatitis B immune globulin within 2 hours of birth and hepatitis B vaccine (10 micrograms) at 0, 1, 2, and 11 months of age (group A) or at 3, 4, 5, and 11 months of age concomitant with diphtheria, pertussis, tetanus, and polio immunization (group B). A second dose of hepatitis B immune globulin was given to infants on schedule B at 3 months.</p><p><strong>Main outcome measures: </strong>Blood samples were collected at 0, 3, 6, 11, and 12 months of age and tested for antibodies against hepatitis B core antigen and HBsAg. Follow-up visits were scheduled annually up to 5 years of age.</p><p><strong>Results: </strong>Eight infants were excluded from analysis. During the study period, six children became HBsAg carriers, three in each group, which corresponds to a 5-year incidence of infection of 9% and 8% for groups A (three of 35) and B (three of 37), respectively. Subclinical infections (persistent anti-HBc positivity beyond month 12 or appearance of anti-HBc) were encountered in another eight infants (four in each group).</p><p><strong>Conclusion: </strong>Late active immunization starting at 3 months of age appears to provide similar protective efficacy as active immunization starting at birth when combined with hepatitis B immune globulin at 0 and 3 months of age.</p>","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 12","pages":"1316-20"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160360058019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19237908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and treatment of nonsteroidal anti-inflammatory drug-induced gastroduodenal injury in children.","authors":"A E Mulberg,&nbsp;M Verhave","doi":"10.1001/archpedi.1993.02160360022008","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160360022008","url":null,"abstract":"","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 12","pages":"1280-1"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160360022008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of congenital heart defects in relatives of patients with atrioventricular canal.","authors":"M C Digilio,&nbsp;B Marino,&nbsp;M P Cicini,&nbsp;A Giannotti,&nbsp;R Formigari,&nbsp;B Dallapiccola","doi":"10.1001/archpedi.1993.02160360037013","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160360037013","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the overall occurrence of congenital heart disease in 103 pedigrees with a proband affected with atrioventricular canal.</p><p><strong>Design: </strong>Family study of patient series.</p><p><strong>Setting: </strong>Department of Pediatric Cardiology, Bambino Gesu' Hospital, Rome, Italy.</p><p><strong>Participants: </strong>One hundred three consecutive patients with atrioventricular canal and normal karyotype and their first- and second-degree relatives.</p><p><strong>Interventions: </strong>None.</p><p><strong>Measurements/main results: </strong>In 12 pedigrees (11.7%), one or more relatives had concordant or discordant congenital heart disease. Congenital heart disease occurred in four (1.9%) of the 206 parents of probands, in four (3.6%) of the 111 siblings, and in five (0.8%) of the 644 uncles or aunts. None of the grandparents had congenital heart disease. Atrioventricular canal affected several family members in five pedigrees.</p><p><strong>Conclusions: </strong>Familial aggregation of atrioventricular canal in several pedigrees requires careful collection of family histories, accurate cardiologic evaluation of the first- and second-degree relatives of the probands, and fetal echocardiography in all pregnant women in at-risk families.</p>","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 12","pages":"1295-7"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160360037013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aspirin and bismuth subsalicylate.","authors":"G Levy","doi":"10.1001/archpedi.1993.02160360023010","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160360023010","url":null,"abstract":"","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 12","pages":"1281"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160360023010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"X-linked lymphoproliferative disease. Detection of a paternally inherited mutation in a German family using haplotype analysis.","authors":"V Schuster,&nbsp;W Kress,&nbsp;W Friedrich,&nbsp;T Grimm,&nbsp;H W Kreth","doi":"10.1001/archpedi.1993.02160360045015","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160360045015","url":null,"abstract":"<p><strong>Objective: </strong>To study the inheritance of the X-linked lymphoproliferative disease (XLP) locus in a German family.</p><p><strong>Design: </strong>Haplotype segregation analysis.</p><p><strong>Setting: </strong>Departments of Pediatrics and Human Genetics, University of Würzburg and University of Ulm, Federal Republic of Germany.</p><p><strong>Participants: </strong>Fourteen members of a family with XLP.</p><p><strong>Interventions: </strong>None.</p><p><strong>Measurements/main results: </strong>Using molecular genetic techniques, we diagnosed the XLP status of the members of a German family. Restriction fragment length polymorphism analysis with closely linked polymorphic X-chromosomal DNA markers (Xq25-q27) revealed XLP carrier status in a female infant. Moreover, the XLP mutation was suggested to have occurred in the germ cell of the grandfather.</p><p><strong>Conclusion: </strong>This is the first report of a paternally inherited XLP mutation. The recurrence risk for germ cell mosaicism in XLP may be similar to that of X-linked Duchenne muscular dystrophy.</p>","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 12","pages":"1303-5"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160360045015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applicability of the Greulich and Pyle skeletal age standards to black and white children of today.","authors":"R T Loder,&nbsp;D T Estle,&nbsp;K Morrison,&nbsp;D Eggleston,&nbsp;D N Fish,&nbsp;M L Greenfield,&nbsp;K E Guire","doi":"10.1001/archpedi.1993.02160360071022","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160360071022","url":null,"abstract":"<p><strong>Objective: </strong>The Greulich and Pyle skeletal age atlas was derived from white children of upper socioeconomic level during the 1930s. To our knowledge, the Greulich and Pyle standards have not been reassessed for both black and white children; it was the purpose of this study to reassess the applicability of these standards to today's children.</p><p><strong>Design: </strong>A \"blinded\" review of hand roentgenograms taken for the evaluation of trauma was performed. Age of the subjects was evenly distributed between 0 and 18 years. The roentgenograms were scored for bone age by five individuals from different disciplines and levels of training. The difference between the median bone age and the child's chronologic age was calculated for each roentgenogram and stratified into four age groups: early childhood (0 to 4 years), middle childhood (4 to 8 years), late childhood (8 to 13 years), and adolescence (13 to 18 years).</p><p><strong>Setting: </strong>The roentgenograms were obtained from four hospital emergency rooms in the Lake Erie basin area, the same geographic area from which the Greulich and Pyle standards originated.</p><p><strong>Patients: </strong>There were 841 children: 452 boys and 389 girls, 461 black and 380 white children.</p><p><strong>Results: </strong>The bone ages and chronologic ages were similar for white girls of all ages. Black girls were skeletally advanced by 0.4 to 0.7 year (P < .001), except during middle childhood. White boys were skeletally delayed during middle childhood by 0.9 year (P < .001) and during late childhood by 0.4 year (P < .01), but they were advanced during the adolescent years by 0.5 year (P < .01). Black boys showed no difference except for the adolescent group, which was skeletally advanced by 0.4 year (P < .02).</p><p><strong>Conclusions: </strong>The Greulich and Pyle atlas is not applicable to all children today, especially black girls. We should be aware of this information when making clinical decisions requiring accurate bone ages.</p>","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 12","pages":"1329-33"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160360071022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19237911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obturator internus muscle abscess: a case report and review of the literature.","authors":"A K Souid,&nbsp;P D Sadowitz,&nbsp;L Weiner,&nbsp;A S Dubansky,&nbsp;M Oliphant","doi":"10.1001/archpedi.1993.02160360020004","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160360020004","url":null,"abstract":"","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 12","pages":"1278-9"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160360020004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The female adolescent athlete and iron.","authors":"R T Brown","doi":"10.1001/archpedi.1993.02160360021005","DOIUrl":"https://doi.org/10.1001/archpedi.1993.02160360021005","url":null,"abstract":"","PeriodicalId":75474,"journal":{"name":"American journal of diseases of children (1960)","volume":"147 12","pages":"1279-80"},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1001/archpedi.1993.02160360021005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19239401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}