H Fujiwara, N Natsume, S Miura, S Inagaki, Y Kanou, T Yamamoto, T Kawai
{"title":"[Experimental study on the cleft lip and palate. VIII. Induction of cleft palate in Wistar rats by vitamin A].","authors":"H Fujiwara, N Natsume, S Miura, S Inagaki, Y Kanou, T Yamamoto, T Kawai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We tried to induce cleft palate in Wistar rats by injecting Vitamin A. We injected Vitamin A into the stomach of females when they were pregnant on the eighth, ninth, tenth and eleventh day. We them sacrificed them to observe the fetuses while they were still pregnant on the eighteenth-twentieth day. The results showed that a high rate of cleft palate could be induced by injecting 5-10 x 10(4) I.U/kg of Vitamin A during pregnancy on the tenth day.</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 3","pages":"629-34"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13783755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Longitudinal study of dental arch forms, with special reference to normal and malocclusions].","authors":"A Sato","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of the present study was to investigate the developmental changes of dental arch forms by using longitudinal materials. The data was derived from dental casts and roentgenographic cephalograms collected from a longitudinal growth study of Japanese children from the age of 5 to 15 years. The materials were divided into three groups of occlusion at the time that the children had full permanent dentitions as follows; normal occlusion group (N-group; N = 19), Angle's class I crowding group (CR-group; N = 11), Angle's class II malocclusion group (CL2-group; N = 7). In addition, members of these groups were classified into three developmental stages as follows; deciduous, mixed and permanent dentition. The developmental changes in dental arch forms were analyzed from metrical measurements of dental casts and roentgenographic cephalograms. The measurements, such as dental arch lengths, widths, amount of interdental space or crowding, mesiodistal crown diameters, overjet and overbite, were obtained from dental casts, and those of incisor inclination angles and ANB angles were from roentgenographic cephalograms. Finally, principal component analysis was performed to clarify the developmental changes of dental arch forms in the series of longitudinal data. The results were as follows; 1. A method was devised for drawing dental arch forms directly from dental casts using compasses, sliding calipers and rulers. 2. Dental arch lengths and widths of the CR-group were uniformly smaller from the deciduous to permanent stages than those of the N-group. 3. The CL2-group showed nearly the same sizes of arch lengths and widths as the N-group at the deciduous stage. Nevertheless, these dimensions of the CL2-group increased considerably and showed larger sizes of arch lengths and widths than the N-group in mixed and permanent stages except in the case of maxillary arch widths. 4. The sum of mesiodistal crown diameters of the CR-group were quite similar to those of the N-group in all three stages. On the other hand, the CL2-group tended to be larger in both arches than the N-group in all stages. 5. So far as the deciduous stage is concerned, the amount of interdental space was significantly larger in the N-group than in the other two groups. 6. Throughout all stages, there were no significant differences in the maxillary central incisor inclination angles among the three groups, while the CR-group tended to show lingual inclination of the mandibular central incisor compared with the other two groups.(ABSTRACT TRUNCATED AT 400 WORDS)</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 3","pages":"635-72"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13783756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Nakano, M Saitoh, Y Yosida, Y Asahina, T Kanazawa, K Hiranuma
{"title":"[Evaluation of masticatory efficiency and the analysis of occlusal pattern factors using computer image processing method].","authors":"K Nakano, M Saitoh, Y Yosida, Y Asahina, T Kanazawa, K Hiranuma","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of this study was to evaluate the newly developed computer-assisted image processing method. We applied this method for the evaluation of masticatory efficiency and the analysis of occlusal pattern factors: the number and the size of occlusal contact areas, the number of and the size of the projected facets. We compared this new method with our conventional one which is the simplified particle counting method using a sieve and measuring the occlusal pattern factors with a planimeter. The results were as follows: 1. It is possible to count the number of particles within an optional range of size with the new method. 2. The new method may be used with minimum error for the measurement of occlusal pattern factors. We believe that this newly developed computer-assisted image processing method can be put to practical use for clinical evaluation of masticatory efficiency and analysis of occlusal pattern factors.</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 3","pages":"607-12"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13783753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Experimental studies of the effect of direct electric micro-current on the healing processes of bone defects].","authors":"D W Kim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>As a procedure to accelerate healing of the bone defect, the electric micro-current has attracted much attention in the field of clinical application and experimental research. However, investigation of the calcifying process and comparison of the elements of the newly formed bony callus have not yet been carried out. In order to get deeper understanding of the callus formation and calcifying process in bone defects, this experiment aimed at comparing the healing processes of bone defects in the rabbit humerus between stimulated and non-stimulated control group. The bone specimens were surgically removed, on the 4th postoperative day and 1st, 2nd, 3rd, and 4th postoperative weeks. The specimens were examined by the use of the computer aided microanalyser, the energy dispersive spectrometer, and the scanning electron-microscope (JCMA-733). Histological examination was also made. In the stimulated group, on the 4th day, Ca and P of low concentration were observed around the inner periosteum indicating initiation of the calcification with callus formation. On the 1st week Ca and P were distributed diffusely in the bone defect. On the 2nd and 3rd weeks, the bone defect was almost filled with new bony callus and the calcification became more intense. After the 4th week, the distribution and concentration of Ca and P in the bony callus were similar to those of the surrounding cortical bone. Furthermore, the molar ratio of Ca/P of the new bony callus was much greater in the stimulated group than in the control group, and was rather similar to the molar ratio of Ca/P in the surrounding cortical bone. The results showed that the electric micro-current facilitated not only callus formation but also calcification, thus shortening the healing period of the bone defect.</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 3","pages":"613-28"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13783754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Natsume, T Suzuki, H Masuda, S Miura, S Sugimoto, Y Kanou, H Fujiwara, S Inagaki, T Nakamura, R Horiuchi
{"title":"[Epidemiological investigation of cleft lip and/or palate. II. Incidence of cleft lip and palate among Japanese babies in Gifu prefecture 1986 to 1987].","authors":"N Natsume, T Suzuki, H Masuda, S Miura, S Sugimoto, Y Kanou, H Fujiwara, S Inagaki, T Nakamura, R Horiuchi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Since 1981 we have been conducting investigations in Aichi Prefecture where our institution is located in close cooperation with Medical Association of Obstetrics-Gynecologists and member physicians of the Midwives Association. In addition, we surveyed 111 institutions in Gifu Prefecture for the patient who was delivered from January 1, 1986 to December 31, 1987 to learn the incidence and type classification of cleft lip and/or palate in the general population Gifu. Consequently, we acquired the date of 20667 newborns. It was found as a result that 35 babies had these abnormalities and that ratio of the birth of such newborns was one for 590.5 deliveries. Among 35 cleft infants 12 (34.3%) with cleft lip and palate, 5 (14.3%) cleft palate. Looking at the estimates from the results of our investigation, the annual number of newborns with these disease in the Gifu Prefecture was 41.6 to 41.9 in 1986, 33.5 to 33.6 in 1987 with 95 percent confidence limits.</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 3","pages":"687-92"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13783758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T Ishijima, M Saitoh, Y Asahina, T Kanazawa, T Imamura, H Gotoh, K Hiranuma
{"title":"[Survey on oral and maxillofacial injuries in contact sports and diffusion of mouthguards].","authors":"T Ishijima, M Saitoh, Y Asahina, T Kanazawa, T Imamura, H Gotoh, K Hiranuma","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recent reports have shown an increase of oral and maxillofacial injuries caused by sports activities. In European and American countries, mouthguards are the popular measure against these injuries. The purpose of this study was to survey the rate of incidence of oral and maxillofacial injuries caused by contact sports, the diffusion and the evaluation of mouthguards and the interest in mouthguards in Japan. Questionnaires were sent to 244 Rugby football teams in Aichi prefecture and 27 American football teams in the Tokai area. We received replies from 153 Rugby football teams and 17 American football teams, and the results were as follows: 1) The rate of incidence of oral and maxillofacial injuries was 239 players out of 4721 players, which means 5.1% in Rugby football and 22 players out of 428 players, which means 5.1% in American football. 2) The diffusion of mouthguards was 20 out of 153 teams in Rugby football and 16 out of 17 teams in American football. And most of them are using commercially available mouthguards. 3) Almost all teams were not satisfied with their mouthguards and complained of speaking difficulties, discomfort and easy dislocation. 4) Almost all teams desire the improvement of mouthguards. 5) Teams with no experience of mouthguards were very much interested in the use of mouthguards but they do not have enough information about mouthguards. 6) We have to enlighten players and their instructors about mouthguards and diffuse the use of mouthguards more positively to contact sports players.</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 3","pages":"673-86"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13783757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Cariogenicity of Propionibacterium acnes, Streptococcus intermedius and Streptococcus mutans in germ-free rats].","authors":"A Ogawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A comparative study has been made on the cariogenic potentials of Propionibacterium acnes ATCC 11828, Streptococcus intermedius OE-1 and Streptococcus mutans OZ-1. The strains of P. acnes and S. intermedius have chondroitinase activity. As metabolic end-products, the P. acnes strain produces mainly a weak acid, propionic acid, whereas strong lactic acid is the main product of the strains of S. intermedius and S. mutans. Five germ-free rats were used for infection with each bacterial strain. The rats were fed with a 25% sucrose diet for 100 days and then sacrificed. The upper and lower molars were used for the determination of the smooth surface caries score. The right upper and lower jaws were used for the preparation of sections which were employed for the determination of the fissure caries score and microradiography. The left upper and lower jaws were decalcified and used for the preparation of thin sections for staining with Gram's, hematoxilin eosin, Mallory's, alcian blue-PAS, silver and toluidine blue stain. The results obtained were as follows: 1. The recoveries of infected cells in the specimens obtained by swabbing the oral cavities were in the order of 10(4) CFU/mg wet weight regardless of the strains injected. 2. Macroscopically, the P. acnes strain decalcified to a lesser extent some of the enamel surfaces of the lower molars. However, the S. intermedius strain produced mainly the fissure caries of the lower molars. The S. mutans strain destroyed the enamel extensively, resulting in the induction of rampant carious lesions. 3. The caries scores of smooth surface determined by Keyes's method were 19.4 +/- 7.8, 46.8 +/- 5.8 and 118.4 +/- 15.4 in the rats infected with the strains of P. acnes, S. intermedius and S. mutans, respectively. The fissure caries score determined by the modified König's method were 8.5, 22.3 and 36.5 in the sections prepared from the rats infected with the strains of P. acnes, S. intermedius and S. mutans, respectively. 4. Microradiography revealed no translucent area in the enamel and dentine of the P. acnes-infected molars, while in the S. intermedius-infected molars translucent areas were found at the dentino-enamel junction neighboring the bottoms of some fissures. The S. mutans-infected molars showed extensive translucent areas over the enamel and dentine of all of the molars. Even defects of the enamel and dentinal areas were observed in some of the molars. 5. The decalcified tooth sections were stained in a similar manner irrespective of the type of organisms used to infect them.(ABSTRACT TRUNCATED AT 400 WORDS)</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 2","pages":"473-93"},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13778791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Changes in concentrations of nerve- and muscle-related proteins during reinnervation of slow and fast muscles].","authors":"H Matsushita","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The concentration of the nerve-related (gamma-enolase) and muscle-related (beta-enolase and creatine kinase of B type) proteins was measured in the rat sciatic nerve and the muscles; soleus (SOL), a typical slow-twitch muscle, and extensor digitorum longus (EDL), a typical fast-twitch muscle. The nerves and muscles were subjected to experimental manipulation of their innervation. 1. Nerve-related protein, gamma-enolase. The concentration of gamma-enolase in the distal part of the transected sciatic nerve was decreased in 2 weeks to about 10% of normal. When the sciatic nerve was sutured immediately after the transection, the concentration of gamma-enolase recovered in 34 weeks to a level of about 62.8% of normal. 2. Fast muscle-related protein, beta-enolase. The concentration of the beta-enolase in the SOL and the EDL was reduced after sciatic nerve transection. When the sciatic nerve was sutured immediately after complete transection, the concentration of beta-enolase of SOL and EDL became almost equal on the 34th week. After cross union of the nerves innervating the SOL and EDL muscles, the concentration of the beta-enolase were almost equal on the 20th post-operative week in the both muscles, and reversed on the 34th week. The beta-enolase concentrations in the SOL and EDL muscles innervated by the TTX-perfused sciatic nerve were reduced to 72.3% and 70.4%, respectively. Continuous electrical stimulation of the sciatic nerve reduced the beta-enolase concentration in the EDL to 51.8% of normal, but did not affect the SOL significantly. 3. Slow muscle-related protein, creatine kinase of B type (CK-B). After complete severance of the sciatic nerve the CK-B concentration showed a marked increase in the both muscles. When the sciatic nerve was sutured immediately after transection, the CK-B concentration on the 34th week was about 35.3% in the SOL and close to normal in the EDL. On the 34th week after cross union of the nerves innervating the SOL and EDL muscles, the CK-B concentration was reduced to about 41.1% in the SOL, while it was increased to about 111% in the EDL. On the 20th week after self re-union of the nerves innervating the SOL and EDL muscles, the CK-B concentration in the EDL recovered the normal level, but in the SOL muscle it was increased significantly. 4. It appears that the measurement of the concentration of gamma-enolase, beta-enolase and CK-B can provide valuable informations on the recovery course of skeletal muscles after nerve injury.</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 2","pages":"397-413"},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13779015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Gustatory information processing in rat medullary solitary tract nucleus].","authors":"S Yamada","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>1. The present experiment aimed at examining the possibility that the taste-sensitive neurons with similar taste-sensitivity are preferentially innervated by common driving neurons whose taste-selectivity is also similar. 2. A pair of glued electrodes was inserted into the unilateral solitary tract nucleus (NTS) of the rat, and simultaneous recordings were made in neuron pairs responding to the four basic taste stimuli. The spike response density (RD) of each neuron during tastant stimulation was determined. Correlation coefficients of spike occurrence were calculated for each neuron pair during application of tastants and distilled water, and also during spontaneous background activity. The frequency of correlated discharge (FC) of a neuron pair was measured as the area of the peak appearing on the cross-correlogram (CC). The FC value was divided by the RD value to calculate the weight of the correlated discharges in the output of each neuron (WC value). 3. Eleven pairs showed peak formation on the CC constructed during tastant stimulation, while in other 11 pairs no peak formation was found. The cross-correlation-positive group with peak formation was composed of 18 NaCl-best (responding most vigorously to NaCl) and 4 HCl-best neurons, while the negative group without peak formation included 9 NaCl-best, 9 HCl-best, and 4 sucrose-best neurons. From the cross-correlation negative group without peak formation the probability to pick up by chance two neurons responding most strongly to the same taste quality was calculated to be 0.367. 4. In 7 cross-correlation-positive pairs out of 11, both of the component neurons were NaCl-best, giving 7/11 = 0.636. 5. In the cross-correlation-positive pairs the best taste of one of the component neurons was often (13 NaCl-best and 2 HCl-best, 15/22 = 0.681) identical to the taste quality giving the highest probability of correlated discharge, i.e., the highest FC value, in the neuron pair. 6. There were 5 cross-correlation-positive pairs (5/11 = 0.455) in which both of the component neurons were NaCl-best and the FC value was highest during NaCl stimulation. 7. The CCs constructed during water application showed peak formation in all the pairs which gave positive cross-correlation following stimulation with tastants, while all the pairs with negative cross-correlation during tastant stimulation never gave a detectable peak during water application. 8. In 3 pairs of the cross-correlation-positive group, the CCs constructed during spontaneous background activity without application of any liquid showed a small peak.(ABSTRACT TRUNCATED AT 400 WORDS)</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 2","pages":"415-28"},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13779016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Murakami, S Takehana, T Abe, Y Yamamoto, M Watanabe, R Tejima, T Takigawa
{"title":"[Dimensional change and deformation on stone dies for full cast crowns. Differences according to impression methods using vinyl silicone impression materials].","authors":"H Murakami, S Takehana, T Abe, Y Yamamoto, M Watanabe, R Tejima, T Takigawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to reconfirm the efficiency of an individual tooth tray, an apparatus and method were developed for measuring dimensional changes and observing over all deformation on a stone die for a full cast crown. The stone dies, which were made by combination impression methods I, II and double impression (individual tooth tray use) with vinyl silicone impression materials, were measured and compared. The results were as follows: 1. It made no difference what kind of vinyl silicone impression materials were used. 2. As to the dimensional changes: for combination impression method I, irregular results were found for the stone dies with the differences between +1 standard deviation (SD) and -1 SD being large. The variations of the other two methods were quite small, indicating that the stone dies were made accurately. 3. Observing to magnified images with the naked eye, there were no clear differences between the three methods on the marginal parts, but at the top corners of the stone dies there were good results with the double impression method. 4. It was possible to grasp easily the general aspect of dimensional changes in the stone dies using this newly developed measuring method.</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 2","pages":"429-40"},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13841760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}