H Fujiwara, N Natsume, S Miura, S Inagaki, Y Kanou, T Yamamoto, T Kawai
{"title":"唇腭裂的实验研究。8维生素A诱导Wistar大鼠腭裂[j]。","authors":"H Fujiwara, N Natsume, S Miura, S Inagaki, Y Kanou, T Yamamoto, T Kawai","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>We tried to induce cleft palate in Wistar rats by injecting Vitamin A. We injected Vitamin A into the stomach of females when they were pregnant on the eighth, ninth, tenth and eleventh day. We them sacrificed them to observe the fetuses while they were still pregnant on the eighteenth-twentieth day. The results showed that a high rate of cleft palate could be induced by injecting 5-10 x 10(4) I.U/kg of Vitamin A during pregnancy on the tenth day.</p>","PeriodicalId":75458,"journal":{"name":"Aichi Gakuin Daigaku Shigakkai shi","volume":"27 3","pages":"629-34"},"PeriodicalIF":0.0000,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Experimental study on the cleft lip and palate. VIII. Induction of cleft palate in Wistar rats by vitamin A].\",\"authors\":\"H Fujiwara, N Natsume, S Miura, S Inagaki, Y Kanou, T Yamamoto, T Kawai\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We tried to induce cleft palate in Wistar rats by injecting Vitamin A. We injected Vitamin A into the stomach of females when they were pregnant on the eighth, ninth, tenth and eleventh day. We them sacrificed them to observe the fetuses while they were still pregnant on the eighteenth-twentieth day. The results showed that a high rate of cleft palate could be induced by injecting 5-10 x 10(4) I.U/kg of Vitamin A during pregnancy on the tenth day.</p>\",\"PeriodicalId\":75458,\"journal\":{\"name\":\"Aichi Gakuin Daigaku Shigakkai shi\",\"volume\":\"27 3\",\"pages\":\"629-34\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Aichi Gakuin Daigaku Shigakkai shi\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Aichi Gakuin Daigaku Shigakkai shi","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
我们尝试通过注射维生素A来诱导Wistar大鼠的腭裂。我们在雌性大鼠怀孕的第8天、第9天、第10天和第11天将维生素A注射到雌性大鼠的胃中。当他们在第十八,二十天还在怀孕的时候,我们献祭他们来观察胎儿。结果表明,妊娠第10天注射5 ~ 10 × 10(4) iu /kg维生素a可致腭裂率高。
[Experimental study on the cleft lip and palate. VIII. Induction of cleft palate in Wistar rats by vitamin A].
We tried to induce cleft palate in Wistar rats by injecting Vitamin A. We injected Vitamin A into the stomach of females when they were pregnant on the eighth, ninth, tenth and eleventh day. We them sacrificed them to observe the fetuses while they were still pregnant on the eighteenth-twentieth day. The results showed that a high rate of cleft palate could be induced by injecting 5-10 x 10(4) I.U/kg of Vitamin A during pregnancy on the tenth day.