{"title":"Thrombin and bradykinin modulate prostaglandin synthetase independently of phospholipase.","authors":"R W Bonser, K A Chandrabose, P Cuatrecasas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thrombin and bardykinin stimulate prostaglandin production from exogenous arachidonic acid in 3T3 cells. The increase in PG production cannot be explained simply by the contribution from endogenous AA metabolism. The rates of stimulated PG production from exogenous and endogenous AA both remain linear fro 3 min, then fall rapidly. It is suggested that BK and Th may act by directly stimulating cyclooxygenase independently of phospholipase.</p>","PeriodicalId":75450,"journal":{"name":"Advances in prostaglandin and thromboxane research","volume":"6 ","pages":"259-62"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17822969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of the arachidonate lipoxygenase pathway in blood platelet aggregation.","authors":"C E Dutilh, E Haddeman, F ten Hoor","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75450,"journal":{"name":"Advances in prostaglandin and thromboxane research","volume":"6 ","pages":"101-5"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17823174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Nompleggi, L Myers, P Ramwell, D Castell, A Dubois
{"title":"PGE2 involvement in the regulation of gastric emptying.","authors":"D Nompleggi, L Myers, P Ramwell, D Castell, A Dubois","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75450,"journal":{"name":"Advances in prostaglandin and thromboxane research","volume":"8 ","pages":"1587-8"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17823559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inhibition of prostaglandins biosynthesis lowers antidiuretic hormone excretion in man.","authors":"P Glasson, M B Vallotton","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75450,"journal":{"name":"Advances in prostaglandin and thromboxane research","volume":"7 ","pages":"1115-8"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18036400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Angiotensin II-induced renal prostacyclin release suppresses platelet aggregation in the anesthetized dog.","authors":"R J Shebuski, J W Aiken","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75450,"journal":{"name":"Advances in prostaglandin and thromboxane research","volume":"7 ","pages":"1149-52"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18036405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PGF2 alpha stimulates release of PGE2 and PGI2 in the isolated perfused rat heart.","authors":"E A de Deckere, F ten Hoor","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of prostaglandin F2 alpha on the release of PGI2 and PGE2 was investigated in isolated perfused rat heart. PGF2 alpha at concentrations of 1.7 nmoles liter-1 or higher increased the release of PGI2 and PGE2 alpha. The release of PGI2 was highest after 3 to 4 min of perfusion with PGF2 alpha. This phenomenon may be of physiological significance and might explain the observed variable effects of PGF2 alpha on vascular resistance.</p>","PeriodicalId":75450,"journal":{"name":"Advances in prostaglandin and thromboxane research","volume":"7 ","pages":"655-8"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18036414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F ten Hoor, E A de Deckere, E Haddeman, G Hornstra, J F Quadt
{"title":"Dietary manipulation of prostaglandin and thromboxane synthesis in heart, aorta and blood platelets of the rat.","authors":"F ten Hoor, E A de Deckere, E Haddeman, G Hornstra, J F Quadt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We conclude that dietary changes can have a profound influence on prostaglandin and thromboxane synthesis of organ systems. A better insight into underlying mechanisms is necessary before more definite advice with respect to feeding a linolenic acid and very long-chain polyunsaturated fatty acids as found in fish oils can be given.</p>","PeriodicalId":75450,"journal":{"name":"Advances in prostaglandin and thromboxane research","volume":"8 ","pages":"1771-81"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18039490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B A Schölkens, W Bartmann, G Beck, U Lerch, E Konz, U Weithmann
{"title":"Vasodilator and antiplatelet activities of prostacyclins with modified omega-side chain.","authors":"B A Schölkens, W Bartmann, G Beck, U Lerch, E Konz, U Weithmann","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75450,"journal":{"name":"Advances in prostaglandin and thromboxane research","volume":"6 ","pages":"341-5"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18039606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D A Blake, J R Niebyl, R D White, K M Kumor, N H Dubin, J C Robinson, P G Egner
{"title":"Treatment of premature labor with indomethacin.","authors":"D A Blake, J R Niebyl, R D White, K M Kumor, N H Dubin, J C Robinson, P G Egner","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75450,"journal":{"name":"Advances in prostaglandin and thromboxane research","volume":"8 ","pages":"1465-7"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18039477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Physiological and biochemical parameters of prostacyclin action on the heart and the coronary vasculature.","authors":"K Schrör, R Rösen, H B Link, P Rösen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75450,"journal":{"name":"Advances in prostaglandin and thromboxane research","volume":"7 ","pages":"625-30"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17219908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}