AIDS and Behavior最新文献

{"title":"Pre-exposure Prophylaxis (PrEP) Awareness and Engagement Among MSM at High Risk of HIV Infection in China: A Multi-City Cross-Sectional Survey","authors":"Jun Du,&nbsp;Sainan Wang,&nbsp;Hongbo Zhang,&nbsp;Tao Liu,&nbsp;Shufang Sun,&nbsp;Cui Yang,&nbsp;Nickolas Zaller,&nbsp;Zhen Dai,&nbsp;Haipeng Zha,&nbsp;Yanqiu Zhao,&nbsp;Yue Zhao,&nbsp;Xuejiao Hu,&nbsp;Han Yan,&nbsp;Pan Gao,&nbsp;Jun Wang,&nbsp;Yehuan Sun,&nbsp;Zhihua Zhang,&nbsp;Operario Don","doi":"10.1007/s10461-025-04633-x","DOIUrl":"10.1007/s10461-025-04633-x","url":null,"abstract":"<div><p>This study aimed to explore the awareness, willingness, and engagement with pre-exposure prophylaxis (PrEP) among high-risk Chinese men who have sex with men (MSM) and to investigate the factors influencing its use. A cross-sectional survey of 1800 HIV-negative MSM was conducted in Chengdu, Suzhou, and Wuhan between June 2022 and February 2023 through in-person and online recruitment methods. Univariate and multivariate logistic regression analyses were used to identify predictors of PrEP use. Bayesian network models were constructed using the <i>bnlearn</i> package in R 4.1.2, and inference was conducted using Netica software. Among the 1800 participants, 1467 had ever heard of PrEP, 696 were aware of its target population, and 195 had taken PrEP in the past 6 months. PrEP use was higher among individuals reporting multiple male sex partners, illicit substance use, alcohol use, HIV testing, PEP use, and sexual partners who had used PrEP. Conversely, having a female sexual partner was a barrier to PrEP use. Bayesian network modeling unveiled factors directly and indirectly impacting PrEP use. Variables like PrEP use of sexual partners, PEP use, alcohol use, HIV testing, and WeChat-based HIV knowledge platforms exhibited direct effects. Indirect effects included having a female sexual partner, number of male sexual partners, and illicit substance use. Despite high awareness, the usage of PrEP remains low among MSM. Encouraging social agencies to leverage social media platforms to provide comprehensive HIV care services, especially to meet the PrEP needs of MSM.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1629 - 1639"},"PeriodicalIF":2.7,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences of Disclosure, Resilience and Viral Suppression among People Living with HIV in Ghana.","authors":"Mary Anne Elizabeth Roach, Talia Loeb, Amrita Rao, Carrie Lyons, Gnilane Turpin, Omar Syarif, Pim Looze, Katarzyna Lalak, Jean Anoubissi, Sophie Brion, Keren Dunaway, Laurel Sprague, Carlos Garcia de Leon Moreno, Daria Matyushina, Elsie Ayeh, Stefan Baral, Katherine Rucinski","doi":"10.1007/s10461-025-04641-x","DOIUrl":"10.1007/s10461-025-04641-x","url":null,"abstract":"<p><p>Support for people living with HIV (PLHIV) as they disclose their HIV status can impact continuity of HIV treatment and adherence to antiretrovirals. In the presence of multi-level adversities, resilience among PLHIV can promote health-seeking behaviors and better health outcomes. However, few studies have examined how disclosure experience and resilience work together to impact HIV treatment outcomes among PLHIV. In this study, we assessed the relationships between HIV disclosure experience, resilience and viral suppression among PLHIV in Ghana. The Stigma Index 2.0 questionnaire was completed by 1827 PLHIV in Ghana in 2021 to assess demographics, experiences of HIV related stigma, resilience-factors, and other self-reported outcomes including viral suppression. Participants were also asked to classify their disclosure experience with friends and family as positive or negative. Multivariable log-binomial models estimated adjusted prevalence ratios (PR) and 95% confidence intervals (CI) for the association between disclosure experience and viral suppression. A dichotomized measure of resilience was evaluated as a potential effect measure modifier, and subgroup analyses explored associations by key population. Overall, those with a positive disclosure experience were more likely to have achieved viral suppression than participants with a negative disclosure experience (PR 1.09, 95%CI:1.00-1.19). This association increased among participants with lower resilience scores (PR 1.33, 95%CI:1.11-1.60). Findings suggest the importance of early positive social interactions for sustained engagement in ART, particularly for marginalized populations who face psychosocial and structural stigmas that challenge resilience. Ultimately, optimizing HIV treatment necessitates interventions that mitigate community stigma and promote resilience-building strategies for PLHIV in Ghana.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation Determinants of PrEP and Behavioral Health Treatment Referral among HIV Test Counselors","authors":"Audrey Harkness,&nbsp;Vanessa Morales,&nbsp;Kyle Grealis,&nbsp;Nequiel Reyes,&nbsp;Daniel J. Feaster,&nbsp;Steven Safren,&nbsp;DeAnne Turner,&nbsp;Raymond R. Balise","doi":"10.1007/s10461-025-04620-2","DOIUrl":"10.1007/s10461-025-04620-2","url":null,"abstract":"<div><p>Pre-exposure prophylaxis (PrEP), an effective biomedical prevention intervention, is not sufficiently reaching populations experiencing high HIV incidence. Behavioral health (BH) treatment addressing mental health and substance use similarly requires increased reach to HIV-affected populations. HIV testing is an opportunity to refer individuals to PrEP and BH treatment. This study, conducted in Miami-Dade County, FL, a domestic HIV epicenter, aimed to assess (1) self-reported rates at which HIV test counselors refer clients to PrEP and BH treatment, (2) barriers and facilitators to PrEP and BH treatment referral, and (3) the relationship between barriers and facilitators and test counselors’ referral rates. Among 127 HIV test counselors, the average PrEP referral rate was 63.8% (SD = 41.5) of those potentially meeting PrEP indications. Insufficient time was associated with lower PrEP referral (OR: 0.64, 95% CI: 0.42–0.99, p = 0.023) and training in PrEP screening was associated with higher rates of PrEP referral (OR: 1.27, 95% CI: 0.98–1.64, p = 0.034). The average BH treatment referral rate was 52.7% (SD = 44.4) of clients who the counselor felt would potentially benefit from treatment. Counselors lacking knowledge of screening (OR: 0.4, 95% CI: 0.2–0.78, p = 0.004), referral procedures (OR: 0.45, 95% CI: 0.23–0.87, p = 0.008), or locations to refer clients (OR: 0.47, 95% CI: 0.25–0.86, p = 0.008), as well as those with higher caseloads (OR: 0.998, 95% CI: 0.997–0.999, p &lt; 0.001) were less likely to refer for BH. Training in substance use screening (OR: 1.26, 95% CI: 0.96–1.64, p = 0.046) and referral (OR: 1.28, 95% CI: 0.99–1.66, p = 0.029) were associated with increased BH referral. Implementation strategies are needed to address key barriers to PrEP and BH referrals in HIV testing contexts.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1492 - 1506"},"PeriodicalIF":2.7,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10461-025-04620-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Substance Use Classes Among YMSM in an HIV Digital Health Intervention Program: Implications for Acceptability, Engagement, and Health Outcomes","authors":"Juan Pablo Zapata,&nbsp;Gregory Swann,&nbsp;Alithia Zamantakis,&nbsp;Krystal Madkins,&nbsp;Elizabeth Caitlin Anne Danielson,&nbsp;Brian Mustanski","doi":"10.1007/s10461-025-04619-9","DOIUrl":"10.1007/s10461-025-04619-9","url":null,"abstract":"<div><p>Young men who have sex with men (YMSM) have high rates of substance use, which increases their risk for HIV. Digital Health Interventions (DHI) have the potential to address HIV risk overall and reduce harms in the context of substance use. However, there is limited research on how YMSM with different substance use patterns respond to HIV DHIs and how these programs impact participant outcomes. In this study, we used latent class analysis (LCA) to identify subgroups of participants with specific substance use behaviors in the Keep It Up! (KIU! ) program, an HIV DHI with prior documented effectiveness. This study involved 2,124 participants in a Type III Hybrid trial, comparing two implementation strategies: one via 22 community-based organizations and another through direct-to-consumer recruitment. Evaluations were done at baseline and 12-week follow-up. This analysis identified four classes of substance use: Low Use (minimal alcohol risks, low illicit drug use, infrequent marijuana), Heavy Use (highest alcohol problems, frequent marijuana, elevated illicit drug use), Alcohol and Marijuana Use (high alcohol problems, frequent marijuana), and Methamphetamine and GBH Use (low alcohol risk, moderate marijuana frequency, high illicit drug use). Participants in the Meth &amp; GHB User class were more likely to have an STI at baseline compared to those in the Low User class. Moreover, Heavy Use, Alcohol &amp; Marijuana Use, and Meth &amp; GHB Use reported a greater number of condomless anal sex partners compared to Low Use. Additionally, although Alcohol &amp; Marijuana Use were more likely to use PrEP at the time of their most recent casual partner at baseline, they exhibited the smallest increase in PrEP use during follow-up compared to the other substance use classes. Our analysis did not unveil substantial differences in the success of implementation in terms of reach, suggesting that both implementation strategies effectively engaged YMSM with different levels of substance use. Our research showed a similar level of engagement, as evidenced by the completion rates of modules and time spent, across all substance use classes. However, those within the Meth &amp; GHB category found the intervention highly acceptable, but less so compared to Low Use and Alcohol &amp; Marijuana Use. Understanding how distinct substance use profiles influence intervention outcomes and exploring varied implementation methods can augment future prevention endeavors, broadening the scope and impact of public health initiatives.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1479 - 1491"},"PeriodicalIF":2.7,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of an Online Self-compassion Group Intervention for Sexual Minority Men Living with HIV: A Pilot Randomized Controlled Trial","authors":"Xinyi Li,&nbsp;Qiong Liu,&nbsp;Yihui Yang,&nbsp;Xi Wang,&nbsp;Guangyu Zhou","doi":"10.1007/s10461-025-04624-y","DOIUrl":"10.1007/s10461-025-04624-y","url":null,"abstract":"<div><p>Sexual minority men living with HIV face challenges affecting their quality of life and medication adherence. While self-compassion has shown promise in improving quality of life, targeted interventions for this group remain limited. This pilot study evaluated the efficacy of an online self-compassion group intervention on quality of life and medication adherence among sexual minority men living with HIV. A six-week online intervention, adapted from the Mindful Self-Compassion program, was implemented in a two-arm randomized controlled trial with 28 participants, comparing the intervention to a waitlist control group. The primary outcomes were quality of life and self-compassion, with medication adherence as a secondary outcome. Measures were taken at baseline, mid-intervention, post-intervention, and 1-month follow-up. Linear mixed-effects model showed that the intervention significantly improved quality of life and medication adherence at post-intervention. Although self-compassion showed no significant improvement, over-identification, an uncompassionate self-responding component, showed marginal improvement at follow-up. This pilot study provides preliminary evidence that a self-compassion intervention may improve quality of life and medication adherence in sexual minority men living with HIV, warranting further research with larger sample sizes and a focus on the underlying mechanisms.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1540 - 1552"},"PeriodicalIF":2.7,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can HIV Post-Exposure Prophylaxis Services Change the Sexual Behavior Characteristics of Men Who Have Sex with Men? A Cohort Study in Guangzhou, China","authors":"Yuzhou Gu,&nbsp;Jinhan Fu,&nbsp;Yefei Luo,&nbsp;Lishan Zhan,&nbsp;Fanghua Liu,&nbsp;Wenting Zeng,&nbsp;Huifang Xu,&nbsp;Yongheng Lu,&nbsp;Yanshan Cai,&nbsp;Zhigang Han","doi":"10.1007/s10461-024-04604-8","DOIUrl":"10.1007/s10461-024-04604-8","url":null,"abstract":"<div><p>This study examines the impact of HIV post-exposure prophylaxis (PEP) on sexual behavior changes in men who have sex with men (MSM), aiming to assess a comprehensive HIV prevention strategy integrating biomedical and behavioral interventions to maximize PEP service effectiveness. From a Guangzhou MSM cohort, participants without prior PEP experience were included. The exposed group received PEP services during follow-up (June 2019–April 2022), while controls did not. Cox proportional hazard regression models assessed PEP’s effects on sexual behavior changes. Of 411 participants (mean age: 30.72), 14.1% received PEP during follow-up. The exposed group showed a higher likelihood of reducing Internet partner-seeking (aHR: 3.58, 95%CI: 1.80–7.10, <i>P</i> &lt; 0.001), decreasing anal intercourse partners (aHR: 3.81, 95%CI: 2.14–6.82, <i>P</i> &lt; 0.001) in the past 6 months, lowering last week’s anal intercourse occurrences (aHR: 3.95, 95%CI: 2.33–6.68, <i>P</i> &lt; 0.001), and improving condom use during past 6 months’ anal intercourse (aHR: 3.94, 95%CI: 1.75–8.90, <i>P</i> = 0.001) and the most recent anal intercourse (aHR: 4.96, 95%CI: 1.77–13.88, <i>P</i> = 0.002) compared to controls. To sum up, PEP services contribute significantly to positive sexual behavior changes in MSM. Strengthening behavioral interventions at PEP’s baseline and follow-up stages is crucial for maximizing comprehensive preventive impact on both biomedical and behavioral aspects in MSM.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 4","pages":"1305 - 1315"},"PeriodicalIF":2.7,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Prevalence of Posttraumatic Stress Disorder Symptoms Found in Well-Treated People with HIV after the Introduction of Patient-Reported Outcome Measures","authors":"Kevin Moody,&nbsp;Colette Smit,&nbsp;Pythia T. Nieuwkerk,&nbsp;Maarten Bedert,&nbsp;Elise Nelis,&nbsp;Jeannine Nellen,&nbsp;Kim Sigaloff,&nbsp;Annouschka Weijsenfeld,&nbsp;Laura Laan,&nbsp;Claire Bruins,&nbsp;Suzanne E. Geerlings,&nbsp;Marc van der Valk","doi":"10.1007/s10461-025-04617-x","DOIUrl":"10.1007/s10461-025-04617-x","url":null,"abstract":"<div><p>People with HIV (PWH) are at greater risk of experiencing mental health problems, such as depression and post-traumatic stress disorder (PTSD). The purpose of our study was to determine the prevalence of posttraumatic stress disorder PTSD in PWH. PWH in care Amsterdam University Medical center (Amsterdam UMC) with access to the electronic patient portal were offered patient-reported outcome measures (PROMs) between May 2022 and May 2023, including the PC-PTSD-5 screen for PTSD as part of routine clinical care. Risk factors for a clinically relevant PC-PTSD-5 score were determined using univariate and multiple logistic regression analyses. Of 2476 PWH included, 1384 (55.9%) had access to the electronic patient portal of whom 474 (34.2%) completed the PC-PTSD-5. PWH without access to the patient portal were more often female, born in low- and middle-income countries, acquired HIV more often via heterosexual contact, and had worse HIV-related outcomes compared to those with access. Of 474 PWH who completed the PC-PTSD-5 screening question, 62 (13.1%) reached the threshold for clinically relevant PTSD. Age less than 50 years (OR 2.29, 95% CI: 1.21–4.35), and having originated from low- or middle-income countries (OR 2.02, 95% CI: 1.09–3.76) were associated with PTSD. Our findings show that 13% of PWH with a well-controlled HIV infection with access to the electronic patient portal at Amsterdam UMC experienced clinically relevant PTSD complaints.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1470 - 1478"},"PeriodicalIF":2.7,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10461-025-04617-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of Social Support and LGBTQ + Community Involvement Among Gay, Bisexual, and Other Men Who Have Sex with Men in Australia and Their Effect on HIV-Related Outcomes: A Latent Class Analysis","authors":"Curtis Chan,&nbsp;Benjamin R. Bavinton,&nbsp;Horas T. H. Wong,&nbsp;John Rule,&nbsp;Loc Nguyen,&nbsp;Steven Spencer,&nbsp;Martin Holt","doi":"10.1007/s10461-025-04632-y","DOIUrl":"10.1007/s10461-025-04632-y","url":null,"abstract":"<div><p>Peer support from social networks of gay, bisexual, and other men who have sex with men (GBMSM) has been recognised as a critical driver of engagement with HIV prevention. Using data from an online cross-sectional survey of 1,032 GBMSM aged 18 or over in Australia, a latent class analysis was conducted to categorise participants based on social support, LGBTQ + community involvement, and social engagement with gay men and LGBTQ + people. Comparisons between classes were assessed using multivariable multinomial logistic regression. Participants were allocated into four classes: ‘Gay men focused’ (<i>n</i> = 293, 28.4%) with high levels of support from gay men, ‘High and diverse’ (<i>n</i> = 75, 7.3%) with high support from people with a range of gender and sexual identities, ‘Moderate overall’ (<i>n</i> = 177, 17.2%) who reported some support from all sources, and ‘Low overall’ (<i>n</i> = 487, 47.2%) who had low support. Lifetime HIV testing was lower in the ‘Low overall’ (78.0%) and ‘Moderate overall’ (81.9%) classes compared to the ‘Gay men focused’ (96.9%) and ‘High and diverse’ (93.3%) groups. Among non-HIV-positive participants (<i>n</i> = 971), lifetime PrEP use was lower in the ‘Low overall’ (28.9%) than the ‘Gay men focused’ group (56.2%) but similar in the ‘High and diverse’ (59.7%) and ‘Moderate overall’ (37.5%) groups. Greater levels of social engagement with gay men and LGBTQ + people were associated with higher levels of HIV testing and PrEP use. Interventions are needed to reach GBM who are less engaged with GBMSM networks or LGBTQ + communities.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1619 - 1628"},"PeriodicalIF":2.7,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10461-025-04632-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acceptability and Feasibility of Self-Collected Dried Blood Spot Specimens for Viral Load Monitoring among Rural Older People Living with HIV","authors":"Jennifer L. Walsh,&nbsp;Sabina Hirshfield,&nbsp;Steven A. John,&nbsp;Katherine G. Quinn,&nbsp;Olivia H. Algiers,&nbsp;Timothy L. McAuliffe,&nbsp;Andrew E. Petroll","doi":"10.1007/s10461-024-04599-2","DOIUrl":"10.1007/s10461-024-04599-2","url":null,"abstract":"<div><p>Self-collected dried blood spot (DBS) samples may be useful in monitoring viral load (VL) in research studies or clinically given that they eliminate the need for participants to travel to study sites or laboratories. Despite this, little information exists about monitoring VL using DBS self-collected at home, and no information exists on DBS for this use among older rural people living with HIV (PLH), a population that could benefit from self-collection given difficulty accessing care. We report on the feasibility and acceptability of self-collected DBS samples, DBS VL results, concordance between self-reported and DBS VL, and factors associated with DBS detectable VL in a rural Southern U.S. sample of PLH aged 50 years and older. Between 2021 and 2022, 61 older rural PLH from 9 Southern U.S. states (<i>M</i>_<i>age</i> = 58, 25% female) completed survey measures and self-collected DBS specimens at home; 51 of these participants completed the same procedures at 3-month follow-up. Nearly all participants (96–98%) collected DBS specimens that could be successfully analyzed for VL, and participants found self-collection highly acceptable. Approximately one quarter of participants had quantifiable detectable VL (≥ 839 copies/mL) at each time point. Concordance between self-reported and DBS VL was 69% at baseline and 82% at follow-up; the majority of those with DBS detectable VL self-reported undetectable VL (86% at baseline and 60% at follow-up). Self-collection of DBS specimens for VL monitoring can add value to research conducted remotely, including research associated with the care of rural and/or older PLH.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 4","pages":"1247 - 1255"},"PeriodicalIF":2.7,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aging Concerns Related to Sexuality and Gender: HIV Prevention and Healthy Aging","authors":"Ryan J. Watson,&nbsp;Peter S. McCauley,&nbsp;Amanda Taylor,&nbsp;Ethan Morgan,&nbsp;Brendan Jacka,&nbsp;Lisa A. Eaton","doi":"10.1007/s10461-025-04627-9","DOIUrl":"10.1007/s10461-025-04627-9","url":null,"abstract":"<div><p>Healthy aging is an important area of research across many populations, but less work has focused on this area among sexual and gender diverse individuals relative to the general population. On the whole, it is known that as the U.S. population ages, increasing attention is needed to understand the intersections between aging, health, and wellbeing. One area of consideration to address in regard to healthy aging is that of HIV prevention, in particular, pre-exposure prophylaxis (PrEP) use. For the current study we assessed these factors in a cross-sectional survey designed to assess disease status and related risk factors among a sample of individuals ≥ 50 years of age (<i>N</i> = 794, <i>M</i>_age = 58.5, range = 50–88) who resided in a metropolitan area in Ohio, USA. Results demonstrated that as overall age increased, general aging concerns decreased. Although HIV status was not related to general aging concerns, in additional models, lifetime PrEP use and six-month PrEP use were both related to greater aging concerns. When evaluating sexual orientation-specific aging concerns, we noted the opposite direction in terms of its relationship with age; as these concerns increased so did age. Further, cisgender women, transgender women, transgender men, and those identifying with a different identity each reported greater sexual orientation related aging concerns compared with cisgender men. Based on the current findings, additional research is needed to more fully understand aging related concerns for older individuals who identify as sexual orientation diverse.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1569 - 1579"},"PeriodicalIF":2.7,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143031768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}