Acta paediatrica Scandinavica最新文献_第2页

Metabolic differences between AGA-and SGA-infants of very low birthweight. III. Influence of postnatal age. 极低出生体重的aga -和sga -婴儿的代谢差异。3出生年龄的影响。

Acta paediatrica Scandinavica Pub Date : 1989-09-01 DOI: 10.1111/j.1651-2227.1989.tb11125.x

G Boehm, H Senger, D Müller, K Beyreiss, N C Räihä

{"title":"Metabolic differences between AGA-and SGA-infants of very low birthweight. III. Influence of postnatal age.","authors":"G Boehm, H Senger, D Müller, K Beyreiss, N C Räihä","doi":"10.1111/j.1651-2227.1989.tb11125.x","DOIUrl":"https://doi.org/10.1111/j.1651-2227.1989.tb11125.x","url":null,"abstract":"Seven very low birthweight (VLBW) infants, small for gestational age (SGA), with moderate intrauterine growth retardation and 7 VLBW-infants, appropriate for gestational age (AGA), fed breast milk fortified with 6 g freeze-dried human milk per 100 ml were studied on the 8th, 21st and 42nd days of life. The protein intake on the study days varied between 2.68 and 3.61 g/kg/day in the SGA-and 2.69 and 3.75 g/kg/day in the AGA-infants. Serum concentrations of total bile acids (BA) and the renal excretion of total nitrogen (TN) as well as alpha-amino-nitrogen (AAN) were measured in all infants on each study day. On the 8th day of life a mean protein intake of 3.2 g/kg/day resulted in higher serum concentrations of BA as well as in a higher renal excretion of TN and AAN in the SGA-infants when compared to the AGA-infants. On the 21st day of life these differences were smaller and only the serum concentration of BA and the renal excretion of AAN were still significantly higher in the SGA-infants. On the 42nd day of life only serum concentrations of total BA were elevated in the SGA-infants when compared to that in the AGA-infants. The observed metabolic differences between moderately SGA-and AGA-infants related to protein and bile acid metabolism diminished during the first weeks of life. The present data suggest that when nutritional management of VLBW-infants is planned, differences in metabolic capacities must be considered and protein intake should be increased with caution and in accordance to the individual metabolic situation of the infants during the first weeks of life.","PeriodicalId":75407,"journal":{"name":"Acta paediatrica Scandinavica","volume":"78 5","pages":"677-81"},"PeriodicalIF":0.0,"publicationDate":"1989-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1651-2227.1989.tb11125.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13738970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Acute gastroenteritis. Changing pattern of clinical features and management. 急性肠胃炎。临床特征变化模式及处理。

Acta paediatrica Scandinavica Pub Date : 1989-09-01 DOI: 10.1111/j.1651-2227.1989.tb11127.x

E Isolauri, T Jalonen, M Mäki

引用次数: 13

Increased faecal alpha-1-antitrypsin excretion in children with persistent diarrhoea associated with enteric pathogens. 与肠道病原体相关的持续性腹泻患儿粪便α -1-抗胰蛋白酶排泄量增加

Acta paediatrica Scandinavica Pub Date : 1989-03-01 DOI: 10.1111/j.1651-2227.1989.tb11067.x

M K Bhan, V Khoshoo, D Chowdhary, R Jain, P Raj, S Jayashree, R Kumar

{"title":"Increased faecal alpha-1-antitrypsin excretion in children with persistent diarrhoea associated with enteric pathogens.","authors":"M K Bhan, V Khoshoo, D Chowdhary, R Jain, P Raj, S Jayashree, R Kumar","doi":"10.1111/j.1651-2227.1989.tb11067.x","DOIUrl":"https://doi.org/10.1111/j.1651-2227.1989.tb11067.x","url":null,"abstract":"The random faecal alpha-1-antitrypsin (AT) excretion (mg/g dry weight of stool) was measured in 30 infants and children (mean age 10.8 +/- 8 mo.) with protracted diarrhoea (duration greater than or equal to 21 days) and failure to thrive and 27 normally nourished children (mean age 13 +/- 4.5 mo.) without any gastrointestinal symptoms in the preceding 12 weeks. The associated factors in patients with protracted diarrhoea and their mean faecal AT during active disease and 3-4 weeks after recovery were as follows: Enteropathogenic E. coli 5 (7.9 +/- 5.5; 3.2 +/- 0.6), Giardia lamblia 4 (3.9 +/- 1.8; 2.5 +/- 0.7), Salmonella typhimurium 3 (4.0 +/- 0.2; 3.8 +/- 0), secondary carbohydrate intolerance 11 (2.5 +/- 0.9; 2.4 +/- 0.8), and others 7 (3.4 +/- 0.7; 3.0 +/- 0.5), respectively. Of all the patients with protracted diarrhoea the mean AT in the E. coli, Giardia and Salmonella groups were significantly higher than the mean in the control group (2.1 +/- 0.8) and following treatment and recovery the values were comparable to that in the controls. All the 6 patients with very high faecal AT (greater than mean + 3 SD of controls) were associated with an enteric pathogen.","PeriodicalId":75407,"journal":{"name":"Acta paediatrica Scandinavica","volume":"78 2","pages":"265-7"},"PeriodicalIF":0.0,"publicationDate":"1989-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1651-2227.1989.tb11067.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13922567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Allergic diseases in Swedish school children. 瑞典学龄儿童的过敏性疾病

Acta paediatrica Scandinavica Pub Date : 1989-03-01 DOI: 10.1111/j.1651-2227.1989.tb11064.x

N Aberg, I Engström, U Lindberg

引用次数: 138

Epilepsy and mental retardation following febrile seizures in childhood. 儿童热性癫痫发作后的癫痫和智力迟钝。

Acta paediatrica Scandinavica Pub Date : 1989-03-01 DOI: 10.1111/j.1651-2227.1989.tb11072.x

S M Wolf, A Forsythe

{"title":"Epilepsy and mental retardation following febrile seizures in childhood.","authors":"S M Wolf, A Forsythe","doi":"10.1111/j.1651-2227.1989.tb11072.x","DOIUrl":"https://doi.org/10.1111/j.1651-2227.1989.tb11072.x","url":null,"abstract":"In an unselected group of children who were seen following an initial febrile convulsion, the frequency of subsequent afebrile seizures was 3.5% and of mental retardation 1%. The most common afebrile seizure type was generalized major (86%). About 3/4 of the children who developed afebrile seizures did so by three years and all by five years following the initial febrile seizure. The children with afebrile seizures differed from those without afebrile seizures in the frequency of neonatal abnormality, family history of mental retardation, focal initial febrile convulsions, and delay in psychomotor milestones before the initial febrile seizure. Only about 1/3 of the children who developed afebrile seizures ever had a recurrent febrile convulsion and none had complex recurrent febrile seizures. Half the children with mental retardation had histories of delay in psychomotor milestones prior to the initial febrile seizure, and no child with mental retardation had any seizure longer than five minutes. The administration of daily phenobarbital did not reduce the frequency of epilepsy, in spite of a significant reduction in the incidence of recurrent febrile seizures. There remains no evidence that the prevention of recurrent febrile convulsions significantly decreases the frequency of afebrile seizures or mental retardation.","PeriodicalId":75407,"journal":{"name":"Acta paediatrica Scandinavica","volume":"78 2","pages":"291-5"},"PeriodicalIF":0.0,"publicationDate":"1989-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1651-2227.1989.tb11072.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14065599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 52

The natural history of IgE sensitisation and atopic disease in early childhood. 儿童早期IgE致敏和特应性疾病的自然历史。

Acta paediatrica Scandinavica Pub Date : 1989-03-01 DOI: 10.1111/j.1651-2227.1989.tb11063.x

P P van Asperen, A S Kemp

{"title":"The natural history of IgE sensitisation and atopic disease in early childhood.","authors":"P P van Asperen, A S Kemp","doi":"10.1111/j.1651-2227.1989.tb11063.x","DOIUrl":"https://doi.org/10.1111/j.1651-2227.1989.tb11063.x","url":null,"abstract":"We have prospectively followed 57 children of atopic parents up to 5 years of age, documenting clinical atopic disease and allergen skin test reactions. The cumulative prevalences of the clinical features of atopic disease over the 5 years were: atopic dermatitis (58%), wheeze (49%), recurrent wheeze (33%), rhinitis (68%) and immediate food reactions (18%). Atopic dermatitis and immediate food reactions predominated in infancy (birth to 20 months) while wheezing was more prominent in later childhood (20 months to 5 years). Rhinitis was common in both infancy and childhood. IgE sensitisation to ingested allergens was prominent in early infancy and was usually transient. Inhaled allergen sensitisation occurred later in infancy and was generally permanent with wheal sizes tending to increase with age. There was a significant association between IgE sensitisation to ingested but not inhaled allergens and all atopic manifestations in infancy, with the exception of rhinitis. In contrast IgE sensitisation to inhaled allergens was associated with rhinitis and wheeze in later childhood. We found two clinical groups. One group, with only ingested allergen sensitisation had a high incidence of atopic dermatitis but low incidence of respiratory symptoms at 5 years of age. The other group, who developed evidence of IgE sensitisation to inhaled allergens, had a high incidence of rhinitis and wheeze but low incidence of atopic dermatitis at 5 years of age.","PeriodicalId":75407,"journal":{"name":"Acta paediatrica Scandinavica","volume":"78 2","pages":"239-45"},"PeriodicalIF":0.0,"publicationDate":"1989-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1651-2227.1989.tb11063.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14064195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 68

The effect of the number of fractions of cranial irradiation on growth in children with acute lymphoblastic leukaemia. 头颅照射次数对急性淋巴细胞白血病患儿生长的影响。

Acta paediatrica Scandinavica Pub Date : 1989-03-01 DOI: 10.1111/j.1651-2227.1989.tb11073.x

J H Brämswig, M Wegele, H J von Lengerke, R P Müller, G Schellong

{"title":"The effect of the number of fractions of cranial irradiation on growth in children with acute lymphoblastic leukaemia.","authors":"J H Brämswig, M Wegele, H J von Lengerke, R P Müller, G Schellong","doi":"10.1111/j.1651-2227.1989.tb11073.x","DOIUrl":"https://doi.org/10.1111/j.1651-2227.1989.tb11073.x","url":null,"abstract":"Growth was documented over a period of 7 years in all long-term survivors treated for acute lymphoblastic leukaemia (ALL) with the DAL-70- (n = 15) and BFM-70-protocol (n = 27). Normal growth was documented in patients of the DAL-70-protocol during and after therapy. In contrast, in children treated with the BFM-70-protocol the mean height standard deviation score (SDS) decreased significantly from 1.21 SDS prior to therapy to 0.80 SDS at the end of therapy (p less than 0.001) and remained unchanged thereafter. Prophylactic cranial irradiation was given in total doses of 15 to 30 Gy. Ten children of the DAL-70- and 20 children of the BFM-70-protocol received 24 Gy of cranial irradiation. No significant change in height-SDS was observed in any patients of the DAL-70- and in 8 patients of the BFM-70- group, who received 24 Gy of cranial irradiation in 16-26 fractions. Adult height in 7 girls and 6 boys was normal and 3.15 cm and 5.06 cm above target height. In the remaining 12 patients of the BFM-70-protocol the total dose of 24 Gy of cranial irradiation was applied in 11-14 fractions. Their height-SDS had fallen significantly from 1.24 SDS before to 0.66 SDS (p less than 0.001) at the end of therapy. Adult height in 4 girls and 6 boys was also normal, but the height increase was comparatively smaller, -2.20 cm below target height in the girls and 1.91 cm above in the boys.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":75407,"journal":{"name":"Acta paediatrica Scandinavica","volume":"78 2","pages":"296-302"},"PeriodicalIF":0.0,"publicationDate":"1989-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1651-2227.1989.tb11073.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14065600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Molybdenum. Normal plasma values at delivery in mothers and newborns. 钼。产妇和新生儿分娩时的正常血浆值。

Acta paediatrica Scandinavica Pub Date : 1989-03-01 DOI: 10.1111/j.1651-2227.1989.tb11079.x

D Bouglé, J Voirin, F Bureau, J F Duhamel, G Muller, M Drosdowsky

引用次数: 263

Function of peripheral blood granulocytes in infants with protracted enteropathy. 慢性肠病患儿外周血粒细胞的功能。

Acta paediatrica Scandinavica Pub Date : 1989-03-01 DOI: 10.1111/j.1651-2227.1989.tb11081.x

R Zaba

{"title":"Function of peripheral blood granulocytes in infants with protracted enteropathy.","authors":"R Zaba","doi":"10.1111/j.1651-2227.1989.tb11081.x","DOIUrl":"https://doi.org/10.1111/j.1651-2227.1989.tb11081.x","url":null,"abstract":"Eighty-six infants between the age of 1.0 to 22 months were hospitalized at the I11 Clinic of Pediatrics, Silesian Academy of Medicine, in the period 1976-1981. Group I comprised 47 infants with protracted enteropathy: Group I a-22 infants with signs of protracted enteropathy in the active course of disease after infection with Salmonella, Proteus and/or Escherichiu coli. Weight loss had a mean value of 31.1f9.4Y0. In 7 infants with suspected coeliac disease total villous atrophy was shown in 3 cases, subtotal villous atrophy in 4 cases. In 10 patients hypoproteinemia was detected in the serum. The number of leukocytes during NBTreduction tests and yeast phagocytosis test ranged from 3700 to 18000 mm3, mean 7 815 mm3. Group I b consisted of 14 infants with protracted enteropathy, weight loss had a mean value of 30.1+8.7%. Tests were carried out during remission of diarrhoea. The number of leukocytes during studies varied from 4000 to 10800 mm’. Group I c comprised 11 children with protracted enteropathy and suspected coeliac disease, during clinical recovery. No clinical and bacteriological signs of infection were identified. Weight loss was 19.7f12.4Y0. Total villous atrophy revealed in 9 children and subtotal villous atrophy in 2 cases. The number of leukocytes varied from 5 500 to 8000 mm3, mean 6 800 mm3. Group I1 consisted of 39 infants, including 24 (Group I1 a) with acute diarrhoea and 15 (Group IIb) during recovery, after remission of diarrhoea (Control Group). The number of leukocytes varied from 4000 to 18 OOO mm3, mean 7 161 mm’. The spontaneous NBT reduction, stimulated NBTreduction as well as phagocytic indices were determined by the method of Park et al. (1) and Walter et al. (2). At the same time a test defining the capacity of yeast phagocytosis was used according to the method of Jacobs & Miller (3).","PeriodicalId":75407,"journal":{"name":"Acta paediatrica Scandinavica","volume":"78 2","pages":"323-4"},"PeriodicalIF":0.0,"publicationDate":"1989-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1651-2227.1989.tb11081.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14065607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperferritinemia in malignant histiocytosis, virus-associated hemophagocytic syndrome and familial erythrophagocytic lymphohistiocytosis. A survey of pediatric cases. 恶性组织细胞增多症、病毒相关的噬血细胞综合征和家族性红细胞淋巴组织细胞增多症中的高铁蛋白血症儿科病例调查。

Acta paediatrica Scandinavica Pub Date : 1989-03-01 DOI: 10.1111/j.1651-2227.1989.tb11068.x

N Esumi, S Ikushima, S Todo, S Imashuku

引用次数: 43