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Acta paediatrica Academiae Scientiarum Hungaricae最新文献

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Effect of glucagon infusion on blood glucose, plasma immunoreactive insulin, growth hormone and adenosine 3'5'-monophosphate in obese children. 胰高血糖素输注对肥胖儿童血糖、血浆免疫反应性胰岛素、生长激素及腺苷3′5′-单磷酸的影响。
Acta paediatrica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01
D Molnár, M Kardos, G Soltész
{"title":"Effect of glucagon infusion on blood glucose, plasma immunoreactive insulin, growth hormone and adenosine 3'5'-monophosphate in obese children.","authors":"D Molnár,&nbsp;M Kardos,&nbsp;G Soltész","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The behaviour of plasma glucose, immunoreactive insulin, growth hormone and adenosine 3',5'-monophosphate (cAMP) in response to glucagon infusion was investigated in obese and control children. Hyperinsulinaemia and low growth hormone levels were found in the obese group. Hyperinsulinaemia did not prevent the glucagon-induced cAMP release in obese children. The plasma cAMP concentration decreased after the first hour of glucagon infusion in both groups. The decline of cAMP concentration was more rapid in the obese group than in the controls, resulting in a significantly lower plasma cAMP level at the end of the glucagon load.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"22 4","pages":"325-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17344462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serological follow-up of children with infectious mononucleosis caused by Epstein-Barr virus. eb病毒所致传染性单核细胞增多症患儿的血清学随访。
Acta paediatrica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01
L Timár, M Koller, J Budai
{"title":"Serological follow-up of children with infectious mononucleosis caused by Epstein-Barr virus.","authors":"L Timár,&nbsp;M Koller,&nbsp;J Budai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ninety children, most under 6 years of age, 73 of whom were suffering from a disease suspect of infectious mononucleosis, were examined serologically for EBV infection. Acute EBV infection was demonstrated in 40 cases. These children were followed up until the end of the second year by examining serum samples taken every month of every third month for anti-VCA-IgM, anti-VCA-IgG, anti-VCA-IgA anti-EBNA, and for the specific antibodies to the components D and R of the early antigen. Heterophil antibodies were examined by agglutination of sheep and horse erythrocytes. The temporal course of the antibody response was similar to those reported in adults while anti-EA-D and heterophil antibodies were demonstrated less frequently.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"22 3","pages":"243-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17335218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Childhood leukaemia: therapeutic and experimental approach. 儿童白血病:治疗和实验方法。
Acta paediatrica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01
D Schuler
{"title":"Childhood leukaemia: therapeutic and experimental approach.","authors":"D Schuler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A summary is given of some activities of the Hungarian Study Group for Childhood Leukaemia. Coordinated efforts within the Study Group led to improved therapeutic results. The median survival of patients diagnosed in 1971 was 12 months. For a comparison, out of the 57 patients diagnosed in 1978, 34 are still in their first remission. Experimental work designed to approach the pathomechanism of the disease provided the following main points of interest. 1. Children diagnosed to have L1 type ALL according to the FAB categories fare better than those with L2. 2. ADA activity was essentially normal in patients being in remission and their parents. 3. Steroid receptor determinations can be of value in the planning of therapy. 4. Very low as well as very high initial WBC count indicates a bad prognosis. 5. Children who possess the DR 5 histocompatibility antigen have a better outlook for long complete remissions and cure. 6. Growth hormone secretion and, accordingly, growth rate was normal in the long surviving patients. 7. There was a slight impairment in the performance IQ of children who were under 6 years of age at the time of diagnosis. 8. Emotional disturbances were universal in all patients, but could be much alleviated by regular psychological care and play activity. 9. So far we observed one patient with a second malignancy: his AML manifested 4 years after the successful removal and chemo-radiotherapy of his brain tumour. 10. Children in long, continuous remission-thought to be cured of their disease-possess normal remission lymphocytes with a significantly shorter cell cycle than controls.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"22 1-2","pages":"99-108"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18068827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fasting biochemical parameters and their relationship to anthropometric measurements in childhood obesity. 儿童肥胖的空腹生化参数及其与人体测量的关系。
Acta paediatrica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01
D Molnár, M Kardos, G Soltész, L Klujber, M Schmelczer
{"title":"Fasting biochemical parameters and their relationship to anthropometric measurements in childhood obesity.","authors":"D Molnár,&nbsp;M Kardos,&nbsp;G Soltész,&nbsp;L Klujber,&nbsp;M Schmelczer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fasting plasma immunoreactive insulin, triglyceride, free fatty acid, cholesterol, glycerol, blood glucose, lactate, pyruvate level, and lactate/pyruvate ratio were measured and an intravenous glucose tolerance test was done in obese and control children. The levels of most of the metabolites and the glucose tolerance were similar in the two groups except for the higher immunoreactive insulin and triglyceride levels in the obese group. Further metabolic alterations could be detected when the obese children were divided into subgroups on the basis of fasting insulin and triglyceride levels, and of glucose tolerance. Only three significant correlations were found between metabolic parameters and anthropometric measurements when the obese group was treated as a whole, but numerous other positive and negative correlations were detected in the subgroups. The most striking and unexpected finding was the negative correlation between cholesterol and free fatty acids and some indices of fatness in the whole obese group and in some subgroups. It is concluded that obese children (\"exogenous obesity\") cannot be regarded as a metabolically homogeneous group and the correlations between anthropometric parameters and plasma metabolites remain to be controversial.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"22 4","pages":"313-24"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18091440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unilateral Potter syndrome with amelia. 单侧波特综合征伴阿米莉亚。
Acta paediatrica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01
L Barta, L Balogh, G Szinay, A Regöly-Mérei
{"title":"Unilateral Potter syndrome with amelia.","authors":"L Barta,&nbsp;L Balogh,&nbsp;G Szinay,&nbsp;A Regöly-Mérei","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a newborn infant, absence of kidney, hypoplasia of the lung, absence of the subclavian artery, of the adnexa, of the upper limb and its acetabulum were found on the right side, together with renal dysgenesis and other anomalies on the left side. It is presumed that the severe anomalies damaging the right part of the body were consequences of an increased intrauterine pressure due to oligohydramnios.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"22 3","pages":"195-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18316907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blood coagulation in healthy and severely ill newborn infants. 健康和重症新生儿的血液凝固。
Acta paediatrica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01
G Gyódi, E Vágvölgyi, L Fekete, A Jakó
{"title":"Blood coagulation in healthy and severely ill newborn infants.","authors":"G Gyódi,&nbsp;E Vágvölgyi,&nbsp;L Fekete,&nbsp;A Jakó","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Normal values of blood coagulation factors were investigated in 30 healthy newborn infants. On the basis of these normal standards 8 infants with DIC were evaluated. All of them had serious underlying diseases. By appropriate treatment of the primary disorder and replacement of depleted procoagulants, the bleeding disorder disappeared in six of eight patients without heparinization. Diagnostic criteria and management of neonatal disseminated intravascular coagulation are discussed.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"22 1-2","pages":"25-32"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18282562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Haematuria: glomerular or non-glomerular? Urinary protein fractions in monosymptomatic haematuria. 血尿:肾小球性还是非肾小球性?单症状性血尿的尿蛋白含量。
Acta paediatrica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01
M Miltényi, G Bóka, H Román, M Visy
{"title":"Haematuria: glomerular or non-glomerular? Urinary protein fractions in monosymptomatic haematuria.","authors":"M Miltényi,&nbsp;G Bóka,&nbsp;H Román,&nbsp;M Visy","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"22 1-2","pages":"71-6"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18282567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Echography of the kidneys in infancy and childhood. 婴儿期和儿童期肾脏超声检查。
Acta paediatrica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01
Z Harkányi, I Török
{"title":"Echography of the kidneys in infancy and childhood.","authors":"Z Harkányi,&nbsp;I Török","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"22 3","pages":"229-36"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18316911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neonatal anthropometry: its value in the assessment of nutritional status and neonatal blood glucose homeostasis. 新生儿人体测量:其在评估营养状况和新生儿血糖稳态中的价值。
Acta paediatrica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01
J Mestyán, I Járai
{"title":"Neonatal anthropometry: its value in the assessment of nutritional status and neonatal blood glucose homeostasis.","authors":"J Mestyán,&nbsp;I Járai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The use and application of neonatal anthropometry in newborns with different body measurements and nutritional evaluation status is reviewed. The neonatal blood glucose level has been used as a model in testing the predictive value of various indices of body size for the capacity of neonatal blood glucose homeostasis. For example, combining weight and length deficit from the expected means for gestational age and relative body measurements such as weight for length and ponderal index not only convey information about the type and magnitude of growth impairment, but are also good predictors of the risk of hypoglycaemia within the different anthropometric groups of growth retarded infants. Efforts have been made to delineate the diagnostic criteria by somatic measurements for identification of the different degrees and types of intrauterine growth deviation. The anthropometric approach to the heterogeneity of the intrauterine growth pattern seems to be a simple and very useful tool in somatic classification and evaluation of the newborn infant. In addition to the assessment of body proportions and nutritional status, the anthropometric approach can be of great help in exploring the relationship of body size and the physiological adaptation to the extrauterine environment.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"22 1-2","pages":"49-69"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18068828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic bullous dermatosis of childhood. 儿童慢性大疱性皮肤病。
Acta paediatrica Academiae Scientiarum Hungaricae Pub Date : 1981-01-01
S Kárpáti, E Török, Z Vajda, I Répay, I Kósnai
{"title":"Chronic bullous dermatosis of childhood.","authors":"S Kárpáti,&nbsp;E Török,&nbsp;Z Vajda,&nbsp;I Répay,&nbsp;I Kósnai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A study of 16 patients with chronic bullous dermatosis of childhood (CBDC) is reported. They were followed up for 0.5 to 4.5 years. Histological and immunofluorescent (IF) study of the skin and local provocation of skin lesions by Trafuril test were carried out in every case, intestinal biopsy in twelve cases. Four patients were found to have IgG, and three IgA, along the skin basement membrane. In nine patients, no immunoglobulins were detectable; these IF negative cases seemed to be pseudonegative. Repeated biopsy and immunoelectronmicroscopic study of the skin may be helpful. In the three patient groups classified on the basis of skin IF studies, there was no difference in the clinical and histological picture, in reaction to Trafuril test and in the result of treatment. The small intestinal mucosa was abnormal in three of twelve patients. A gluten-free diet introduced in two patients had no effect on the course of the disease. CBDC with negative or positive IF, juvenile pemphigoid and IgA linear dermatosis seem to be a common clinical entity, different in severity and with individual variations. The condition is not identical with dermatitis herpetiformis Duhring.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"22 4","pages":"331-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18091441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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