{"title":"Developmental changes in lymphocyte surface markers.","authors":"E Walcz, I Seri, D Kuti, T Révész, D Schuler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of the study was to establish normal values for TG and TM cells in neonates and small babies who are more susceptible to infections than children and adults. For the same reason, the T- and B-lymphocyte ratios were also determined. The percentage of B- and T-cells in neonates was significantly lower, while their absolute number higher, than the adult value. The percentage of TG cells was significantly higher in neonates than in the other age groups. There was a significant decrease in the ratio of TM cells as compared to adult values. Spontaneous thymidine uptake showed an inverse correlation with age, but the difference was not significant. There was a nearly identical response to PHA in the observed age groups, at least to the single dose of PHA applied.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"23 3","pages":"299-307"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17281648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T Ertl, E Sulyok, M Németh, I Tényi, I F Csaba, F Varga
{"title":"Hormonal control of sodium content in human milk.","authors":"T Ertl, E Sulyok, M Németh, I Tényi, I F Csaba, F Varga","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The possible role of prolactin (PRL) and aldosterone (Aldo) in regulation of Na content of human milk was investigated. Simultaneous determinations of Na and K in milk, PRL and Aldo in maternal plasma and milk were performed on postpartum days 2, 4 and 6, in samples from 15 mothers giving birth at term and from 8 mothers giving preterm birth. Na concentration and Na/K ratio in milk, Aldo concentration in milk and maternal plasma decreased significantly with advancing lactation. In preterm plasma and milk PRL concentration remained unchanged, whereas in term plasma PRL decreased, milk PRL increased significantly by the 6th day post partum. After preterm delivery milk Na and K levels were significantly higher, maternal plasma and milk Aldo slightly lower than after delivery at term. Daily Aldo and PRL excretion into the milk markedly increased during lactation irrespective of the length of gestation and showed a significant negative correlation with milk Na level and Na/K ratio. It is suggested that the increasing rate of Aldo and PRL excretion into the milk may be of importance in the regulation of Na concentration in human milk.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"23 3","pages":"309-18"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18195362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Major anomalies of the genitourinary tract in the neonate.","authors":"A Pintér","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Thirty-two neonates were investigated or operated upon for major anomalies of the genitourinary tract during the ten-year period up to June 1981. The infants ranged in age from 1 to 31 days. Obstructive uropathies and conditions which appear mainly in later infancy or childhood were excluded. Diagnostic and therapeutic problems of renal dysplasia (multicystic kidney), infantile polycystic kidney disease, renal venous thrombosis, tumours, exstrophy of the bladder, combination of paediatric surgical and urological anomalies, and sex assignment in infants are discussed with some case reports.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":" ","pages":"51-8"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35266293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abnormal dermatoglyphics in absence of thumb.","authors":"L Borbolla","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Dermatoglyphics of six patients with absence of thumb are described. Two specific abnormal configurations were seen in the palmar area. In the first, there was no axial triradius and the course of the ridges in the proximal part of the palm was transversal. In the second, a peculiar distal loop on the radial border was present with a palmar triradius. These abnormal patterns are probably due to the absence of a thenar volar pad or the presence of an abnormal one when the ridges are formed.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"23 4","pages":"417-21"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18184187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F Katona, M Balázs, M Berényi, P Szabados, K Izsák
{"title":"Subdural effusion in the first six months of life.","authors":"F Katona, M Balázs, M Berényi, P Szabados, K Izsák","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>During the period 1978-1981, among 1280 (0-12 months old) infants suffering from consequences of various pre- and perinatal cerebral lesions, positive neuroradiological changes were found in 148 cases. Of these, 56 proved to be real subdural effusions with elevated ICP and increased protein content. Periodical transfontanellar taps and drainage were effective in 49 cases. A neurosurgical operation was performed in 7 infants because of the poor effect of the above treatment. In these 7 infants the encapsulation process was nearly complete. Early chronic subdural effusion exerts a devastating influence on the maturing brain partly by the high ICP. Early treatment often cures the process and major surgery is not needed. Early neurorehabilitation and habilitation coordinated with elimination of the effusion is the method of choice. Prudence is recommended in selecting the appropriate cases for instrumental therapy because some small effusions and fluid accumulations may disappear by the end of the first year.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"23 2","pages":"219-29"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18152276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congenital postural deformity association.","authors":"I Pazonyi, A Kun, A Czeizel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The so-called congenital postural deformities were evaluated in the material of the Hungarian Congenital Malformation Registry, 1970-1976. Seven categories of postural deformities: dislocation of the hip, clubfoot, torticollis, musculoskeletal, other limb, face-nose and auricular were separated. The occurrence of the combination of dislocation of the hip, clubfoot and torticollis is manifold of random combination. These three postural deformities, however, are not associated more often with other nonpostural type abnormalities. Thus the congenital postural deformity association composed of two or more combinations of dislocation of the hip, clubfoot and torticollis without other major congenital abnormalities is treated as a provisional entity. Its birth prevalence is 0.4 per 1000 total births thus after Down syndrome it is the second common type of multiple congenital abnormalities. The aetiology and its higher sib-occurrence are explained by intrauterine maternal moulding factors.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"23 4","pages":"431-45"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18184188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intravenous glucose tolerance test in childhood obesity: metabolite levels and their relation to glucose utilization rate (KG).","authors":"D Molnár, M Kardos, G Soltész, S Baranyai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intravenous glucose tolerance tests were performed in 33 obese and 12 nonobese children. In addition to the glucose disappearance rate the changes in response to the glucose load in plasma insulin, FFA, glycerol, cholesterol, triglyceride, lactate and pyruvate were examined. The relationship between biochemical parameters and the glucose disappearance rate was also studied. 1. Reduced glucose tolerance, basal and glucose-induced hyperinsulinaemia were frequent in the obese children. 2. Normal or reduced glucose tolerance in spite of the apparent hyperinsulinaemia and the negative correlation between fasting insulin level and KG in the nonhypertriglyceridaemic obese group was the marker of insulin resistance in overweight children. 3. The reduced elevation of FFA in the 2nd hour of the intravenous glucose tolerance test might be the sign of an impaired lipolysis in obesity. 4. The significant negative correlation found between KG, fasting FFA and triglyceride levels in certain obese subgroups suggested the importance of FFA and triglyceride in the regulation of peripheral glucose utilization.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"23 2","pages":"127-35"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17806267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z Tóth, J Vachter, G Szeifert, Z Nemes, K Csécsei, O Török, A Harsányi, Z Papp
{"title":"Antenatally diagnosed thanatophoric dysplasia.","authors":"Z Tóth, J Vachter, G Szeifert, Z Nemes, K Csécsei, O Török, A Harsányi, Z Papp","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case of antenatally diagnosed thanatophoric dysplasia is described. Other syndromes accompanied by chondrodysplastic tetramicromelia were excluded and diagnosis was based on the narrow thorax, secondary pulmonary hypoplasia and macrocephaly detected by ultrasound and on radiological findings of disturbed bone formation. At the mother's request labour was induced and radiological, anatomic and histological examination of the newborn confirmed the prenatal diagnosis. On basis of the literature, the possible aetiology of the disease is discussed and autosomal recessive heredity is suggested. Attention is focussed on the significant hydramnios which led to the suspicion of fetal malformation. The importance in pregnancy of routine ultrasound screening is emphasized, since such malformations can be detected as early as in midtrimester pregnancy.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"23 4","pages":"423-30"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17815555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of intravenous alanine on blood glucose, glucagon and growth hormone levels in diabetic children.","authors":"G Soltész, D Molnár, J Mestyán","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To study its glycaemic effect and to evaluate alpha cell function, L-alanine was administered intravenously (0.15 g/kg b.w.) to ketotic diabetic children. Their preinfusion condition was characterized by hyperglycaemia, elevated alanine, glucagon and growth hormone levels. Alanine failed to cause a further increase in the plasma glucagon level and had no glycaemic effect, but induced a consistent rise in plasma growth hormone. It is concluded that, in contrast with adult diabetics, alanine had no glycaemic effect and was not a potent alpha-cell secretagogue in ketotic diabetic children. The demonstrated growth-hormone provoking effect suggests that endogenous hyperalaninaemia may contribute to ketosis via the antiinsulin effect of growth hormone.</p>","PeriodicalId":75405,"journal":{"name":"Acta paediatrica Academiae Scientiarum Hungaricae","volume":"23 2","pages":"195-200"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17865756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}