Acta neurochirurgica. Supplementum最新文献

Monitoring of Cerebral Blood Flow and Metabolism in Intensive Care 重症监护中脑血流和代谢的监测

Acta neurochirurgica. Supplementum Pub Date : 2012-02-28 DOI: 10.1007/978-3-7091-9302-0

A. Unterberg, G. Schneider, W. Lanksch

引用次数: 7

The effects of atrial natriuretic peptide on brain edema, intracranial pressure and cerebral energy metabolism in rat congenital hydrocephalus. 心房利钠肽对先天性脑积水大鼠脑水肿、颅内压及脑能代谢的影响。

Acta neurochirurgica. Supplementum Pub Date : 1994-01-01 DOI: 10.1007/978-3-7091-9334-1_27

J Minamikawa, H Kikuchi, M Ishikawa, K Yamamura, M Kanashiro

{"title":"The effects of atrial natriuretic peptide on brain edema, intracranial pressure and cerebral energy metabolism in rat congenital hydrocephalus.","authors":"J Minamikawa, H Kikuchi, M Ishikawa, K Yamamura, M Kanashiro","doi":"10.1007/978-3-7091-9334-1_27","DOIUrl":"https://doi.org/10.1007/978-3-7091-9334-1_27","url":null,"abstract":"Atrial natriuretic peptide (ANP) regulates fluid and electrolyte homeostasis in the central nervous system. In this study, we evaluated the effects of ANP on brain edema, intracranial pressure (ICP) and cerebral energy metabolism in congenital hydrocephalus in rats. Brain edema, indicated by the longitudinal relaxation time (T1), was evaluated by 1H-magnetic resonance imaging (MRI). The ICP was monitored with a miniature pressure-transducer with telemetric system. Cerebral energy metabolism, indicated by PCr/Pi ratio, was measured by 31P-magnetic resonance spectroscopy (MRS). The rats were given 10 microliters of ANP in the left cerebral ventricle. Three different concentrations of ANP were given; 0.2 (group I), 2.0 (group II) and 20.0 (group III) micrograms/10 microliters, respectively. 10 microliters of saline was injected into the ventricle of the control group rats. There were no significant changes of ICP, T1 value and PCr/Pi ratio among the control group, group I and group II. In group III, in contrast, ICP decreased significantly at 20 minutes after ANP administration and stayed at this ICP level for 60 minutes. The T1 value decreased and PCr/Pi ratio increased 30 minutes after ANP administration. This study revealed that intraventricularly administered ANP could decrease ICP, reduce brain edema and improve the cerebral energy metabolism in rats with congenital hydrocephalus.","PeriodicalId":75393,"journal":{"name":"Acta neurochirurgica. Supplementum","volume":"60 ","pages":"104-6"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18970424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

The cause of acute brain swelling after the closed head injury in rats. 大鼠闭合性颅脑损伤后急性脑肿胀的原因。

Acta neurochirurgica. Supplementum Pub Date : 1994-01-01 DOI: 10.1007/978-3-7091-9334-1_124

H Kita, A Marmarou

{"title":"The cause of acute brain swelling after the closed head injury in rats.","authors":"H Kita, A Marmarou","doi":"10.1007/978-3-7091-9334-1_124","DOIUrl":"https://doi.org/10.1007/978-3-7091-9334-1_124","url":null,"abstract":"The major component of acute brain swelling was determined using a new closed head injury (CHI) model in rats. Twenty seven Sprague-Dawley rats were separated into four groups (Sham, CHI, CHI combined with hypotension and CHI combined with hypoxia and hypotension). Hypoxia (pO2 of 40 mmHg) and hypotension (mean arterial blood pressure of 30 to 40 mmHg) were induced immediately after head injury and were maintained for 30 minutes. These experiments were terminated at two hours after CHI by transcalvarial freezing with liquid nitrogen. Blood pressure, intracranial pressure (ICP) and physiological parameters were monitored. Regional cerebral blood volume and water content were measured quantitatively. Rats with CHI, and with CHI and hypotension, had mild increase in ICP. Otherwise, rats with CHI, hypoxia and hypotension showed a significant increase in ICP (36.2 +/- 5.6 mmHg). Water content showed an increase of 1.6% in the estimated total brain and 2.4% in the cerebral cortex in those rats. Cerebral blood volume decreased by 61.4% in the total brain and 57.3% in the cortex. There was a reduction in the cerebral hematocrit of 2.4% in the total brain and 4.7% in the cortex. The main component of brain swelling in this head injury model was brain edema. Cerebral blood volume and hematocrit were reduced in the remarkable edematous brain.","PeriodicalId":75393,"journal":{"name":"Acta neurochirurgica. Supplementum","volume":"60 ","pages":"452-5"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18970443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 43

Growth kinetics of a primary brain tissue necrosis from a focal lesion. 局灶性脑组织坏死的生长动力学。

Acta neurochirurgica. Supplementum Pub Date : 1994-01-01 DOI: 10.1007/978-3-7091-9334-1_115

J Eriskat, L Schürer, O Kempski, A Baethmann

{"title":"Growth kinetics of a primary brain tissue necrosis from a focal lesion.","authors":"J Eriskat, L Schürer, O Kempski, A Baethmann","doi":"10.1007/978-3-7091-9334-1_115","DOIUrl":"https://doi.org/10.1007/978-3-7091-9334-1_115","url":null,"abstract":"Secondary brain damage, such as brain edema or impairment of the cerebral microcirculation may evolve from tissue necrosis of the brain induced by trauma or ischemia. This laboratory has provided novel information on the secondary increase of a primary brain tissue necrosis resulting from a focal lesion. We have presently investigated more closely the growth kinetics of this process during 24 h after trauma. Rats were subjected to a standardized focal freezing injury of the brain. Area and volume of the resulting necrosis were quantitatively assessed by morphometry after different periods of survival (i.e., 5 min, 3, 6, 12, 18 and 24 h after trauma). The maximal area of necrosis increased by 45% (p < 0.001) during the posttraumatic observation period. Growth of necrosis after trauma was not limited to the early period, but continued between 12 and 24 h, amounting then to 29% (p < 0.05). The volume of necrosis calculated on the basis of histological serial sections was also observed to increase by 45%. The current findings confirm that a primary brain tissue lesion induced by a standard cryogenic injury, studied as model of a contusion focus in severe head injury, is subjected to secondary growth within a period of 24 h after trauma, longer periods of survival were not investigated yet. Quantification of lesion growth makes possible not only to study underlying mechanisms, but also of whether this process can be therapeutically inhibited.","PeriodicalId":75393,"journal":{"name":"Acta neurochirurgica. Supplementum","volume":"60 ","pages":"425-7"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18971241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 35

Is the swelling in brain edema isotropic or anisotropic? 脑水肿的肿胀是各向同性还是各向异性?

Acta neurochirurgica. Supplementum Pub Date : 1994-01-01 DOI: 10.1007/978-3-7091-9334-1_41

T Kuroiwa, M Ueki, Q Chen, S Ichinose, R Okeda

{"title":"Is the swelling in brain edema isotropic or anisotropic?","authors":"T Kuroiwa, M Ueki, Q Chen, S Ichinose, R Okeda","doi":"10.1007/978-3-7091-9334-1_41","DOIUrl":"https://doi.org/10.1007/978-3-7091-9334-1_41","url":null,"abstract":"A study was conducted to examine whether swelling of the brain due to vasogenic-type and cytotoxic-type edema is isotropic or anisotropic. Vasogenic edema was induced by cryogenic injury in cats, and coronal sections of the brain were examined at 4-5 h after injury. The swelling of the edematous white matter longitudinal to and transverse to the subcortical neuronal fibers was 2.3% and 91.1%, respectively. Ischemic edema was examined using cortical tissue specimens of cat brain subjected to either middle cerebral artery occlusion for 3 h or immersion in saline after decapitation for 3 h. The swelling parallel to the left-right axis, caudo-rostral axis and antero-posterior axis was 9.6%, 10.1% and 8.5%, respectively. Neuroglial cell swelling was prominent in the ischemic cortex. Thus swelling of the white matter in vasogenic-type edema was anisotropic, whereas that of gray matter in cytotoxic-type (ischemic) edema was isotropic. This observed difference in the biomechanical properties of brain tissue should be taken into account when the etiology of edema-mediated tissue injury, such as herniation, secondary bleeding or ischemia is investigated.","PeriodicalId":75393,"journal":{"name":"Acta neurochirurgica. Supplementum","volume":"60 ","pages":"155-7"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18971636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Effects of antihistaminics on experimental brain edema. 抗组胺药对实验性脑水肿的影响。

Acta neurochirurgica. Supplementum Pub Date : 1994-01-01 DOI: 10.1007/978-3-7091-9334-1_20

L Schilling, M Wahl

引用次数: 11

Localization of experimental brain tumors in MRI by gadolinium porphyrin. 钆卟啉在MRI上对实验性脑肿瘤的定位。

Acta neurochirurgica. Supplementum Pub Date : 1994-01-01 DOI: 10.1007/978-3-7091-9334-1_93

K Bockhorst, T Els, K Kohno, M Hoehn-Berlage

引用次数: 8

Peritumoral edema in meningioma: a contrast enhanced CT study. 脑膜瘤的瘤周水肿:增强CT研究。

Acta neurochirurgica. Supplementum Pub Date : 1994-01-01 DOI: 10.1007/978-3-7091-9334-1_97

U Ito, H Tomita, O Tone, H Masaoka, B Tominaga

{"title":"Peritumoral edema in meningioma: a contrast enhanced CT study.","authors":"U Ito, H Tomita, O Tone, H Masaoka, B Tominaga","doi":"10.1007/978-3-7091-9334-1_97","DOIUrl":"https://doi.org/10.1007/978-3-7091-9334-1_97","url":null,"abstract":"The propagation of extravasated contrast medium around 6 supratentorial meningiomas with peritumoral white matter of low density (PWL) of Lanksch II-III was investigated by repeated CT scanning at 4 h intervals, following a 1 h drip infusion of 200 ml of Iopamidol. The volume of the expanding peritumoral contrast enhancement was calculated according to a method previously described. By calculating the increase in volume from the first to the second scan, and from the second to third, we derived the rate of edema formation as well as the resolution rate of edema in the PWL. The surface area of the entire tumor (TS) and area of tumor surface facing the PWL (LS) were calculated by summating the surface areas of all CT slices, each area of which was derived from the measured length of the entire circumference of the tumor and circumference of the tumor facing the PWL, respectively, multiplied by the slice thickness of 0.5 cm. The volume of PWL, edema formation rate of entire tumor, and tumor volume x LS/TS were well correlated with each other. We concluded that the severity of peritumoral edema in meningiomas depends on the size of the tumor and the extent of tumor surface contact with the PWL.","PeriodicalId":75393,"journal":{"name":"Acta neurochirurgica. Supplementum","volume":"60 ","pages":"361-4"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18973986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Acta neurochirurgica. Supplementum Pub Date : 1994-01-01 DOI: 10.1007/978-3-7091-9334-1_102

G S Cruickshank, R Rampling

引用次数: 6

The effect of blood volume replacement on the mortality of head-injured patient. 血容量置换对颅脑损伤患者死亡率的影响。

Acta neurochirurgica. Supplementum Pub Date : 1994-01-01 DOI: 10.1007/978-3-7091-9334-1_132

T Sakano, S Yamayoshi, K Higashi, H Ikeuchi, Y Abe, Y Kinoshita, M Kishikawa, K Katsurada

引用次数: 2