{"title":"Depression and Its Associated Factor Among Women Using Hormonal Contraceptives: A Cross-Sectional Study in Jimma Town Public Health Facilities, Southwest Ethiopia, 2022.","authors":"Beniam Worku, Nafyad Tolosa","doi":"10.1089/whr.2024.0100","DOIUrl":"https://doi.org/10.1089/whr.2024.0100","url":null,"abstract":"<p><strong>Background: </strong>Depression is a significant mental disorder that affects >350 million individuals globally. It is noteworthy that females are approximately twice as likely as males to experience depression, with the incidence of depression in females rising during early adolescence. The fluctuation in levels of gonadal hormones contributes to the increased occurrence of depression in females. The use of hormonal contraceptives suppresses the natural production of these hormones, which, in turn, raises the risk of developing depressive symptoms in women. The complex relationship between fluctuating hormones and depression in women is multifaceted, with both natural hormonal changes and hormonal contraceptive use potentially impacting emotional well-being and susceptibility to affective disorders.</p><p><strong>Methods: </strong>An institution-based cross-sectional study was conducted on a sample of 423 individuals. A simple random sampling technique was used for participant selection. The Beck Depression Inventory II screening tool, along with pretested structured interview questionnaires, was used to collect sociodemographic information as well as data on the use of hormonal contraceptives and menstrual history. Trained nurses administered the questionnaires and measured the body mass index (BMI) using standard measuring tools. The collected data were entered into Epi-Data Manager version 4.4.1 and then exported to Statistical Package for Social Sciences version 26 for statistical analysis. Bivariate and multivariate logistic regression analyses were performed to determine the association between dependent and independent variables. All explanatory variables with a <i>p</i>-value <0.25 in bivariate analysis were entered into the multivariable logistic regression model. A <i>p</i>-value <0.05 in the multivariate logistic regression analysis was used to determine statistically significant variables.</p><p><strong>Results: </strong>The prevalence of depression among the study participants was 38.8%. The age category 18-25 years, poor social support, uncomfortable marital relationship, injectable hormonal contraceptives, and BMI status >25 kg/m<sup>2</sup> were variables that became significantly associated with depression in this study.</p><p><strong>Conclusions: </strong>This study has shown that the prevalence of depression among contraceptive users was 38.8%. The age-group of 18-25 years, poor social support, an uncomfortable marital relationship, use of injectable hormonal contraceptives, and a BMI status >25 kg/m<sup>2</sup> have an impact on the prevalence of depression. Based on these findings, it is recommended that women's health initiatives prioritize mental health services. Providing adequate mental health support and counseling can help address the prevalence of depression among contraceptive users. It is also suggested that health care providers carefully evaluate the risks and benefits for women before initiating hormon","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"6 1","pages":"293-304"},"PeriodicalIF":1.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gehad Ahmad Saleh, Omar Hamdy, Dina Ragab, Bassante Farouk, Mennatalla Mahmoud Allam, Rawan Abo Asy, Fatmaelzahraa A Denewar, Mohamed Ezat
{"title":"Fibrothecoma of the Ovary; Clinical and Imaging Characteristics.","authors":"Gehad Ahmad Saleh, Omar Hamdy, Dina Ragab, Bassante Farouk, Mennatalla Mahmoud Allam, Rawan Abo Asy, Fatmaelzahraa A Denewar, Mohamed Ezat","doi":"10.1089/whr.2024.0153","DOIUrl":"https://doi.org/10.1089/whr.2024.0153","url":null,"abstract":"<p><strong>Introduction: </strong>Ovarian fibrothecoma is a rare benign sex cord-stromal ovarian tumor sorted under the thecoma-fibroma group. We present an analysis of clinical and laboratory findings and the radiological characteristic features of pathologically proven fibrothecomas in variable imaging modalities.</p><p><strong>Methods: </strong>A retrospective analysis was done for 88 patients with 90 pathologically proven ovarian fibrothecoma between January 2011 and December 2023 from our center's prospectively maintained database. All the patients underwent preoperative ultrasonography, computed tomography (CT), and magnetic resonance imaging (MRI) scans, clinical examinations, basic laboratory tests, and tumor markers.</p><p><strong>Results: </strong>The results of Spearman's correlation revealed a statistically significant positive correlation between the largest tumor diameter and serum level. CA 125, the degree of ascites, and diffusion weighted imaging (DWI) signal intensity while the results of point biserial correlation revealed a statistically significant correlation of the largest tumor diameter with the presence of ascites, cystic changes, abdominal enlargement, surgery type, and border type. There were also statistically significantly higher hypoechoic lesions in the smaller tumor group (<i>p</i> = 0.001) but not for isoechoic (<i>p</i> = 0.099) and mixed (<i>p</i> = 0.052). Regarding the MRI, there was a statistically significantly larger tumor diameter in T2 mixed-hyperintense versus hypointense (<i>p</i> = 0.007) and intermediate (<i>p</i> = 0.010) signal intensities.</p><p><strong>Conclusion: </strong>Fibrothecoma showed a statistically significant positive correlation between the largest tumor diameter with serum level CA 125 and the amount of ascites. On imaging, it shows mild enhancement in both CT and MRI, with a statistically significant positive correlation of the largest tumor diameter with T2 and DWI signal intensity.</p>","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"6 1","pages":"315-324"},"PeriodicalIF":1.6,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachelle Chanmany Pastor, Lisa Roberts, Akshat Jain, Shan Tamares
{"title":"The Heat Is On: Climate Change Implications for Pregnant Women with Sickle Cell Disease.","authors":"Rachelle Chanmany Pastor, Lisa Roberts, Akshat Jain, Shan Tamares","doi":"10.1089/whr.2024.0146","DOIUrl":"https://doi.org/10.1089/whr.2024.0146","url":null,"abstract":"<p><p>Sickle cell disease (SCD), a serious, chronic blood disorder is the most common genetic blood disease in the United States affecting 100,000 people and disproportionately affecting the African American population. Pregnancy is particularly risky for people with SCD due to higher risk of developing pregnancy-related complications compared with people without the disease. For African American pregnant women with SCD, the risk of maternal morbidity and mortality is up to 10 times higher. Physiological changes during pregnancy increase the risk of vaso-occlusive episodes (VOEs), acute chest syndrome, venous thromboembolic events, and infections. Dehydration increases risk as it triggers sickling of red blood cells, leading to painful VOEs and further increasing the risk of aforementioned complications. Climate change, observed since the mid-20th century, is evidenced by the increasing trend of global temperature, hurricanes, floods, and heat waves. Climate changes can profoundly impact people with SCD, as elevated temperatures result in increased core body temperatures, blood hyperosmolality, and dehydration. Assisted by a research librarian, a literature search was undertaken of major databases (PubMed, Embase, and Google Scholar), with delimiters of publication between 2019 and 2024 and human subjects, and 477 studies were retrieved. After meticulous screening, 20 relevant articles were analyzed. Evidence linking climate change impact to increased risk for pregnant people with SCD is lacking. Further research is needed to examine the phenomenon and mitigate this unique risk of climate change. SCD clinical guidelines stress the importance of preventing dehydration. Clinicians play a critical role in educating this vulnerable population about risks, including dehydration and exposure to extreme heat.</p>","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"6 1","pages":"286-292"},"PeriodicalIF":1.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daryn H David, Ishita S Arora, Azza Hussein, Jessica Gois Santana, Cindy A Crusto, Darin Latimore
{"title":"Women's Leadership Development at the Yale School of Medicine: Preliminary Evaluation of an Innovative Program.","authors":"Daryn H David, Ishita S Arora, Azza Hussein, Jessica Gois Santana, Cindy A Crusto, Darin Latimore","doi":"10.1089/whr.2024.0188","DOIUrl":"https://doi.org/10.1089/whr.2024.0188","url":null,"abstract":"<p><strong>Background: </strong>Despite strong data indicating women leaders' proven efficacy as catalysts for organizational change, there is significant attrition for women across the advancement, promotion, and leadership pathways within academic medicine. To help early-career women faculty build a network of support, enhance leadership capacity and agility, and gain the skills necessary for career advancement and fulfillment, we created the Women's Leadership Development Program (WLDP) at our medical school in 2020.</p><p><strong>Methods: </strong>From 2023 to 2024, we collected retrospective survey data from all interested prior participants to gauge the impact of the WLDP on faculty members' confidence, sense of belonging at Yale School of Medicine, and acquisition of leadership skills.</p><p><strong>Results: </strong>Findings indicate the WLDP's positive impact on women faculty members' sense of leadership efficacy and skills, with participants reporting enhanced appreciation of their leadership potential, knowing how to lead with their strengths, improved leadership vision, and increased confidence in making an impact in academic medicine going forward.</p><p><strong>Conclusion: </strong>The importance of leadership development programming for the professional development of early-career women faculty in academic medicine is explored. The article concludes with implications of these findings for our ongoing programming and leadership development initiatives for women in academic medicine more broadly.</p>","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"6 1","pages":"274-285"},"PeriodicalIF":1.6,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melanna Cox, Paige F Richmond, Annie Shtino, John R Sirard
{"title":"Exploring the Endorsement of Gender Stereotypes and Physical Activity in Young Women.","authors":"Melanna Cox, Paige F Richmond, Annie Shtino, John R Sirard","doi":"10.1089/whr.2024.0117","DOIUrl":"https://doi.org/10.1089/whr.2024.0117","url":null,"abstract":"<p><strong>Background: </strong>Physical behaviors (PBs), defined as physical activity (PA) and sedentary behavior (SB), are consistently less favorable in women than men. Extensive qualitative research has identified gender norms as a well-known barrier to women's PA, but they have yet to be clearly conceptualized and quantified. The purpose of this study was to (1) investigate the relationship between benevolent sexism endorsement (BSE) and PB, (2) explore women's experiences with sexism in PA settings, and (3) identify sexism constructs within focus group discussions.</p><p><strong>Methods: </strong>Participants completed the Ambivalent Sexism Inventory (0-5 scale) and wore a hip-worn activity monitor for 7 days. Spearman correlations were calculated between BSE and PB. A 90-minute focus group (<i>n</i> = 4) was transcribed and coded to identify themes and sexism constructs.</p><p><strong>Results: </strong>Participants (<i>n</i> = 20, 20.7 ± 1.3 years) exceeded PA guidelines and reported low BSE scores (1.8 ± 0.76). Weak associations were found between BSE and objectively measured PA (<i>r</i> = -0.19 to <i>r</i> = -0.37) and ST (<i>r</i> = 0.14). Focus group results yielded four themes: (1) Age-Related Decline in PA, (2) Parental Roles, (3) Peer Relationships/Friendships, and (4) Physical Education Teachers/Coaches.</p><p><strong>Conclusion: </strong>As hypothesized, associations between BSE and PA outcomes and SB were negative and positive, respectively. Focus group themes were related to benevolent sexism constructs. Future research should be conducted in larger, more diverse samples and consider other factors that may impact one's endorsement of benevolent sexism.</p>","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"6 1","pages":"249-262"},"PeriodicalIF":1.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charlotte R Esplin, Lisa Calderwood, Chantel M Weisenmuller, Jessica L Luzier
{"title":"Experiences of Women Faculty in an Academic Medical Center.","authors":"Charlotte R Esplin, Lisa Calderwood, Chantel M Weisenmuller, Jessica L Luzier","doi":"10.1089/whr.2024.0138","DOIUrl":"https://doi.org/10.1089/whr.2024.0138","url":null,"abstract":"<p><strong>Background: </strong>Women faculty face different obstacles in academic medical careers than their men counterparts. Women faculty report feeling like \"outsiders\" and experiencing multiple barriers to career advancement compared with men, especially if they hold a nonmedical degree (<i>e.g.</i>, PhD). This study examined aspects of workplace culture that differentially impact women at a large regional academic medical center (AMC) in the Appalachian region of the United States-a geographic area that is largely understudied in this body of literature.</p><p><strong>Materials and methods: </strong>Forty-seven women completed a survey that included the Culture Conducive to Women's Academic Success instrument, the Professional Fulfillment Index, the Work and Family Conflict scale, and items measuring burnout, childcare availability, and demographic factors.</p><p><strong>Results: </strong>Our findings revealed that many women faculty felt that they were being treated differently than men faculty, that work infringed on their home and family life, and that while they were professionally fulfilled at work, childcare problems exacerbated feelings of wanting to leave that AMC. About 60% of our sample indicated some level of burnout.</p><p><strong>Conclusions: </strong>These findings align with previous findings that women juggle multiple roles that are typically not expected of men, and this juggling may be one reason why women are not staying in academic medicine or being promoted at the same rate as men. We provide incremental validity for the measures used and delineate specific ideas for improvement, such as on-site childcare, standardized leave policies, and formal mentorship and curriculum programs.</p>","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"6 1","pages":"263-273"},"PeriodicalIF":1.6,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bridging the Gap in Diabetes and Fracture Care for Diverse Populations.","authors":"Nicklas H Rasmussen","doi":"10.1089/whr.2024.0200","DOIUrl":"https://doi.org/10.1089/whr.2024.0200","url":null,"abstract":"","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"6 1","pages":"236-238"},"PeriodicalIF":1.6,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caroline A Dancu, Julie Schexnayder, Hayden B Bosworth, Allison Lewinski, Abigail Shapiro, Tiera Lanford, Courtney White Clark, Bevanne Bean-Mayberry, Leah L Zullig, Jennifer M Gierisch, Karen M Goldstein
{"title":"Tailoring Chronic Disease Interventions to Meet Specific Needs of Women: A Case Example of a Hypertension Program.","authors":"Caroline A Dancu, Julie Schexnayder, Hayden B Bosworth, Allison Lewinski, Abigail Shapiro, Tiera Lanford, Courtney White Clark, Bevanne Bean-Mayberry, Leah L Zullig, Jennifer M Gierisch, Karen M Goldstein","doi":"10.1089/whr.2024.0139","DOIUrl":"https://doi.org/10.1089/whr.2024.0139","url":null,"abstract":"<p><strong>Background: </strong>Women have a unique risk profile for cardiovascular disease (CVD) due to underlying sociocultural and biological determinants. Current CVD prevention and treatment interventions, however, largely remain agnostic to the influences of an individual's sex assigned at birth or gender identity. This study describes a process for tailoring existing evidence-based interventions to the biological and sociocultural determinants of health for women.</p><p><strong>Methods: </strong>This study adapted the Team-supported, Electronic Health Record (EHR)-leveraged, Active Management (TEAM) CVD preventative care intervention designed for telehealth-based remote hypertension (HTN) care in rural Veterans. Tailoring choices were informed by a 12-month process including a focused literature review, qualitative interviews with women's health experts, and feedback from providers and women Veterans on existing intervention materials.</p><p><strong>Results: </strong>Literature review and qualitative interview findings informed the modification of patient- and provider-facing TEAM materials. Patient-facing material modifications included the addition of information relevant to sex-specific CVD risk factors, addressing gender-related barriers to CVD risk reduction, and including diverse visual representation and inclusive language. Provider-facing materials were modified through a new EHR template to comprehensively address sex-specific CVD risk factors. These changes resulted in individualized care plans to better address gaps in HTN management among women.</p><p><strong>Conclusion: </strong>Tailoring existing evidence-based interventions is an achievable and practical strategy to incorporate the sociocultural and biological determinants of CVD health specific to women. This approach could be used to adapt other programs and interventions designed to address health conditions that occur among both men and women but which are sensitive to important biological and sociocultural determinants. These findings highlight the broad discourse on sex- and gender-sensitive health care interventions and advocate for the integration of these interventions into routine clinical practice.</p>","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"6 1","pages":"239-248"},"PeriodicalIF":1.6,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fahamina Ahmed, Kaylin Miller, Meva Beganovic, Ali Siddiqui, Candice Smith
{"title":"A Sex Comparison of Fall and Fracture Occurrence in the Elderly Diabetic Population: A Quantitative Study.","authors":"Fahamina Ahmed, Kaylin Miller, Meva Beganovic, Ali Siddiqui, Candice Smith","doi":"10.1089/whr.2024.0158","DOIUrl":"https://doi.org/10.1089/whr.2024.0158","url":null,"abstract":"<p><strong>Aims: </strong>To assess differences in falls and fractures in men and women with type 2 diabetes mellitus (T2DM) within a diverse population in Southeast Louisiana.</p><p><strong>Methods: </strong>A list of 1200 patients was generated through an electronic health record system using keywords: diabetic diagnosis, falls, and fractures to conduct this retrospective cohort study. This chart review included adults with T2DM who experienced at least one fall and/or fracture between January 2018 and May 2023 at East Jefferson General Hospital located in Metairie, Louisiana. Only falls and fractures that resulted in a hospital visit were included. Results were compared between males and females.</p><p><strong>Results: </strong>Patient data were collected from 100 randomly selected patients: 50 females and 50 males (mean age 67 years, 97% of patients were non-Hispanic, and 72% Black). Statistical analysis was conducted using the Student's <i>t</i> test, Fisher's exact, and Pearson correlation. An average of 3-4 falls occurred per patient, with no significant sex difference observed (<i>p</i> = 0.97). Thirty-eight percent of patients experienced a fracture with a significant sex difference (50% of female vs. 26% of male patients [<i>p</i> = 0.02]). Positive correlations between comorbid conditions and falls and fractures were seen, particularly in women: a moderate correlation for falls (<i>r</i> = 0.48, <i>p</i> < 0.01) and a strong correlation for fractures (<i>r</i> = 0.52, <i>p</i> < 0.01). Patients not on insulin treatment experienced a greater occurrence of fractures than insulin-dependent patients (46% vs. 22%, <i>p</i> = 0.03).</p><p><strong>Conclusions: </strong>Our findings suggest that in a diverse population, women with T2DM are at an increased risk of experiencing fractures, and specialized care should be given to this population to reduce the risk of fracture occurrence. Additional comorbidities increase the risk of falls and fractures.</p>","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"6 1","pages":"230-235"},"PeriodicalIF":1.6,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Josep Perelló-Capó, Gregorio López-González, María Isabel Lahoz-Pascual, Ana Isabel López-Castejón, Manuel Marcos-Fernández, Mercedes Andeyro-García, Ignacio Cristóbal-García, Joan Rius-Tarruella
{"title":"Understanding Discontinuation Rates and Acceptance of the Low-Dose Levonorgestrel Intrauterine System in Spain: A Comprehensive Analysis of Bleeding Patterns and Influencing Factors.","authors":"Josep Perelló-Capó, Gregorio López-González, María Isabel Lahoz-Pascual, Ana Isabel López-Castejón, Manuel Marcos-Fernández, Mercedes Andeyro-García, Ignacio Cristóbal-García, Joan Rius-Tarruella","doi":"10.1089/whr.2024.0113","DOIUrl":"10.1089/whr.2024.0113","url":null,"abstract":"<p><strong>Purpose: </strong>To estimate the 1-year continuation rate of low-dose levonorgestrel-releasing intrauterine systems (LNG-IUS) in Spanish women and elucidate potential factors impacting continuation.</p><p><strong>Materials and methods: </strong>A prospective, multicenter, noninterventional study with a 1-year follow-up was conducted in Spain. Participants were 18-35-year-old women using low-dose LNG-IUS. Clinical and demographic data were collected, and the association between baseline characteristics and discontinuation rate was analyzed.</p><p><strong>Results: </strong>A total of 289 women (9.3% using 13.5 mg LNG-IUS and 90.6% using 19.5 mg LNG-IUS) completed the study, and 9% discontinued prematurely after 12 months. A statistically significant association was found between LNG-IUS discontinuation and educational level (odds ratio [OR] = 2.63; 95% confidence interval [CI]: 1.07-6.48), previous pregnancies (OR = 3.44; 95% CI: 1.40-8.46), and baseline intensity of menstrual pain (OR = 1.03; 95% CI: 1-1.04). In addition, both the change in the menstrual bleeding's interference with daily life activities between the final and basal visit and the change in the pain associated with the intensity of menstrual bleeding showed a significant association with discontinuation.</p><p><strong>Conclusions: </strong>When recommending LNG-IUS, a patient's baseline characteristics such as educational level, previous pregnancies, intensity of menstrual pain, and menstrual bleeding's interference with daily life activities have to be considered. By doing so, health care providers can improve contraceptive counseling, reduce discontinuation rates, and enhance women's satisfaction.</p>","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"6 1","pages":"209-220"},"PeriodicalIF":1.6,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}