Veterinary medicine (Auckland, N.Z.)最新文献

{"title":"Application of Advanced Imaging Modalities in Veterinary Medicine: A Review","authors":"Dagmawi Yitbarek, Gashaw Getaneh Dagnaw","doi":"10.2147/VMRR.S367040","DOIUrl":"https://doi.org/10.2147/VMRR.S367040","url":null,"abstract":"Abstract Veterinary anatomy has traditionally relied on detailed dissections to produce anatomical illustrations, but modern imaging modalities, now represent an enormous resource that allows for fast non-invasive visualizations in living animals for clinical and research purposes. In this review, advanced anatomical imaging modalities and their applications, safety issues, challenges, and future prospects of the techniques commonly employed for animal imaging would be highlighted. The quality of diagnostic imaging equipment in veterinary practice has greatly improved. Recent advances made in veterinary advanced imaging specifically about cross-sectional modalities (CT and MRI), nuclear medicine (PET, SPECT), and dual imaging modalities (PET/CT, PET/MR, and SPECT/CT) have become widely available, leading to greater demands and expectations from veterinary clients. These modalities allow for the creation of three-dimensional representations that can be of considerable value in the dissemination of clinical diagnosis and anatomical studies. Despite, the modern imaging modalities well established in developed countries across the globe, it is yet to remain in its infancy stage in veterinary practice in developing countries due to heavy initial investment and maintenance costs, lack of expert interpretation, a requirement of specialized technical staff and need of adjustable machines to accommodate the different range of animal sizes. Therefore, veterinarians should take advantage of these imaging techniques in designing future experiments by considering the availability of these varied imaging modalities and the creation of three-dimensional graphical representations of internal structures.","PeriodicalId":75300,"journal":{"name":"Veterinary medicine (Auckland, N.Z.)","volume":"13 1","pages":"117 - 130"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48488176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Identification of Mange Mites on Cattle in and Around Nekemte Town, East Wollega Zone, Oromia Regional State, Western Ethiopia","authors":"A. Kebede, Shafi Hirpa","doi":"10.2147/VMRR.S353983","DOIUrl":"https://doi.org/10.2147/VMRR.S353983","url":null,"abstract":"Purpose Mange mite is one of the skin diseases of cattle that can cause huge economic loss through a decrease in production. Methods A cross-sectional study was conducted with the objective of determining the prevalence and identification of species of mange mites that affect cattle in and around Nekemte town. The study methods involved were clinical and laboratory examinations of skin scraping samples from the animals. Results From 384 examined animals, 86 (22.40%) were found to be infected with mange mites. The most commonly encountered mange mite genus was Sarcoptes (15.10%), Demodex (5.47%) and Psoroptes (1.82%). The higher prevalence was observed in young animals, 49 (22.69%), compared to adult animals, 37 (22.02), but statistically insignificant variations were observed. Also a non-significant variation was found between sexes (P ≤ 0.067), even though it was higher in female, 72 (23.00%) than male, 14 (19.72%), but a statistically significant variation was observed among body condition score (P ≤ 0.024), with the highest prevalence being in poor body condition score, 31 (57.41%). A statistically significant variation was detected among the body part infestation (P ≤ 0.024). The most frequent sites of mange mite infestation were the shoulder, neck, face, ears, tail and legs, respectively. Conclusion The study indicated that there was high prevalence of mange mite infestation in cattle in the study area that needs appropriate and strategic control measures by employing additional research for species identification and improving the standards of animal husbandry.","PeriodicalId":75300,"journal":{"name":"Veterinary medicine (Auckland, N.Z.)","volume":"13 1","pages":"109 - 116"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42047168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprevalence and Associated Risk Factors of Mycoplasma gallisepticum Infection in Poultry Farms of Hawasa and Bishoftu, Central Ethiopia","authors":"J. Shiferaw, Firaol Shifara, M. Tefera, A. Feyisa, Yobsan Tamiru","doi":"10.2147/VMRR.S360669","DOIUrl":"https://doi.org/10.2147/VMRR.S360669","url":null,"abstract":"Background Mycoplasma gallisepticum (MG) infection is an economically important respiratory disease in the poultry production system worldwide. It is characterized by rapid transmission and causing many obstacles to poultry industries in different parts of Ethiopia. Methods A cross-sectional study was employed from January to September 2021 to estimate the seroprevalence and associated risk factors of MG in domestic layer chickens in large and small commercial poultry farms in Hawassa and Bishoftu area, Ethiopia. A total of 368 blood samples were collected. Data were analyzed using SPSS version-20, reported as percent prevalence, and Pearson's chi-square was used to assess the association between factors considered to have association with MG infection. The samples were processed by using an indirect ELISA (ProFLOKIBV, USA) test coated with antibody against MG. Results The total seroprevalence of MG infection was found to be 70.65%. Significant variation in environmental risk factors with seroprevalence was assessed and the higher prevalence of MG was significantly (χ2 = 14.42; p < 0.05) higher in layer chicken farms found in Bishoftu. Likewise, it was significantly observed in the adult chicken and commercial production system. There were significant difference between breeds and ages of birds with the occurrences of MG (χ2 = 19.60 and χ2 = 17.46, respectively). Management related risk factors found around the types of farms were significantly different with the occurrences of MG (OR = 52.5; p < 0.05). Conclusion The evidence from seroprevalence of the MG infection in the current finding provides an indication of the eminence of infection in the study areas. Moreover, it provides an insight on the prevalence of MG infection and further molecular characterization of the organism needs to be conducted in the areas. Biosecurity measures combined with vaccination and sero-monitoring should also be implemented in the farms.","PeriodicalId":75300,"journal":{"name":"Veterinary medicine (Auckland, N.Z.)","volume":"13 1","pages":"101 - 107"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46581404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and Molecular Detection of Newcastle Disease Virus from Field Outbreaks in Chickens in Central Ethiopia.","authors":"Takele Worku, Morka Dandecha, Deraje Shegu, Abde Aliy, Demessa Negessu","doi":"10.2147/VMRR.S352727","DOIUrl":"10.2147/VMRR.S352727","url":null,"abstract":"<p><strong>Background: </strong>Newcastle disease is a major viral disease of poultry. The virus is a major problem for chickens in Ethiopia and there is a scarcity of updated information on the virological and molecular status of confirmation of Newcastle disease outbreak cases in the country.</p><p><strong>Methods: </strong>Newcastle disease outbreaks were investigated from February 2021 to October 2021 in central Ethiopia to isolate and detect the virus by cell culture and reverse transcriptase PCR. A total of 44 pooled tissue specimens were sampled from sick and recently dead chickens showing typical clinical signs of Newcastle disease. Virus isolation were performed using DF-1 cells and detection of the virus was done by real-time PCR.</p><p><strong>Results: </strong>Out of 44 collected tissue samples, 38.63% (17/44) were positive on DF-1 cells. The result shows 17 of the clinically sick and dead chickens were positive for the virus by reverse transcriptase polymerase chain reaction. Based on the sample type, 54.54% (6/11) of the brain samples, 36.36% (4/11) of the intestines, 54.54% (6/11) of lung and trachea, 9% (1/11) of pooled liver, kidney, heart, and spleen samples were positive. Viruses were isolated in the proportions 37.5% (6/16), 25% (2/8), 50% (2/4), 25% (1/4), 50% (2/4) and 50% (4/8) from Sebeta, Bishoftu, Sululta, Nifas Silk, Kolfe and Yeka, respectively.</p><p><strong>Conclusion: </strong>This study showed that Newcastle disease is a major viral disease causing death of chickens in the study area. Therefore, any control approach should focus on the appropriate characterization of the virus strain causing the outbreak in the study area.</p>","PeriodicalId":75300,"journal":{"name":"Veterinary medicine (Auckland, N.Z.)","volume":"13 1","pages":"65-73"},"PeriodicalIF":1.7,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48059753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Vitamin Supplementation on Egg Production, Egg Quality, and Mortality of Sasso Chickens","authors":"Endalkachew Hailu, Yitayew Demessie, Asnake Mulaw","doi":"10.2147/VMRR.S344808","DOIUrl":"https://doi.org/10.2147/VMRR.S344808","url":null,"abstract":"Introduction Ethiopia has a huge poultry population that plays a role in rural development. However, feed shortage is a major problem. Vitamin supplementation in feed formulation is crucial to improve the productivity of poultry. The objective of this study was to evaluate extra doses of vitamin supplements in quality egg production. Methods This experimental study was conducted on Sasso Ruby T chickens aged 22 weeks. The experimental and control groups each contained 60 hens. For the study group, extra doses of vitamins were added to the drinking water. Weekly observation was carried out for 3 months for a total of 12 observations. The effect of extra doses of vitamins on layers in terms of mortality, egg production, egg size, egg-specific gravity, and eggshell thickness was analyzed using SPSS 20 with t-tests. Results Significant changes were observed for mortality (P<0.05), with mean mortality of 0.25±0.45 and 0.66±0.65 and general mortality of 5% and 13% in the study and control groups, respectively. Average egg production per week in the study group (279.5±3.80) was significantly (P<0.05) higher than the control group (256±4.81). However, no significant difference (P>0.05) was found for egg size between the groups: study group 59.99±0.92 g and control group 59.34±0.95 g. There was no significant variation (P>0.05) in average egg-specific gravity: study group 1.068±5.33×10−3 and control group 1.061±5.33×10−3. Average eggshell thickness was significantly greater (P<0.05) in the study group(0.36±0.048 mm) than the control group (0.32±0.04 mm). Conclusion We identified that extra vitamin supplements for layer chickens is very important to increase profitability in the poultry industry by decreasing mortality and increasing egg production.","PeriodicalId":75300,"journal":{"name":"Veterinary medicine (Auckland, N.Z.)","volume":"13 1","pages":"85 - 90"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43067903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and Molecular Detection of Pasteurellosis from Pneumonic Sheep in Selected Areas of Amhara Region, Ethiopia: An Implication for Designing Effective Ovine Pasteurellosis Vaccine","authors":"Aragaw Ebabu Akane, G. Alemu, Kidest Tesfaye, Destaw Asfaw Ali, T. Abayneh, A. Kenubih, M. Ejo, Anmaw Shite Abat, Bemrew Admassu, S. M. Ibrahim","doi":"10.2147/VMRR.S365267","DOIUrl":"https://doi.org/10.2147/VMRR.S365267","url":null,"abstract":"Introduction Pneumonic pasteurellosis mainly caused by bacterial species of Mannheimia, Pasteurella, and Bibersteinia causes a significant financial loss to the sheep production sector through reduced productivity and high mortality. There is a dearth of information on the major agents involved in the disease in the Amhara region, Ethiopia. Therefore, the aim of this study was to isolate and molecularly confirm Mannheimia, Pasteurella, and Bibersteinia from nasal swabs of sheep suspected of pneumonic pasteurellosis in selected areas of the Amhara region. Methods Isolation and phenotypic characterization were performed using microbiological and biochemical testing according to standard methods. Molecular confirmation of isolates was done through amplification of virulence associated genes, PHSAA and Rpt2, of Mannheimia hemolyticausing multiplex PCR. Results Accordingly, 46 out of 141 (32.62%) samples were presumably identified as M. hemolytica with no Pasteurella multocida and Bibersteinia trehalosi. Seven (n=7) out of the 46 isolates tested positive for either of the two virulence genes. Discussion and conclusion The finding of this study is indicative that M. hemolytica is the main bacteria linked with pneumonic pasteurellosis in the study area which suggests the need to develop a polyvalent vaccine including strains of M. hemolytica or its antigenic determinants. However, the role of other bacterial, viral, and parasitic agents in the cases investigated should also be considered.","PeriodicalId":75300,"journal":{"name":"Veterinary medicine (Auckland, N.Z.)","volume":"13 1","pages":"75 - 83"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47952008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Associated Risk Factors of Ovine Oestrosis in Dendi District of Central Ethiopia.","authors":"Askale Gizaw,&nbsp;Petros Admasu,&nbsp;Achalu Nagasa,&nbsp;Solomon Shiferaw,&nbsp;Morka Dandecha Bayu,&nbsp;Adem Abdella","doi":"10.2147/VMRR.S349995","DOIUrl":"https://doi.org/10.2147/VMRR.S349995","url":null,"abstract":"<p><strong>Background: </strong>Ovine oestrosis is an economically important and widely distributed parasitic disease of sheep that is caused by <i>Oestrus ovis</i> larvae across the world. Despite the fact that <i>Oestrus ovis</i> is a common parasite in Ethiopia and that there are many sheep in the study area, there is no information on the prevalence, larval burden, predilection sites, and risk factors associated with <i>Oestrus ovis</i> infestation in sheep in the Dendi district of West Shewa Zone, Ethiopia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from November 2017 to April 2018, to estimate the prevalence, risk factors, and larval burden, and identify common predilection sites for <i>Oestrus ovis</i> larvae. A total of 180 sheep heads were randomly selected from five purposely selected restaurants in Ginchi town, Dendi district, transported to the laboratory, opened with a hand saw, and visually examined for infestations. The larvae were collected from positive sheep heads and counted. The sites where the larvae were obtained were recorded. The data were analyzed using SPSS version 20 software.</p><p><strong>Results: </strong>Of the total of 180 examined sheep heads, 104 (57.8%) were infested with larvae of <i>Oestrus ovis</i>. In the study, a statistically significant difference (p > 0.05) was not observed in the prevalence of <i>Oestrus ovis</i> in relation to all considered risk factors such as sex, age, and origin of sheep. From 104 infested sheep, a total of 664 larvae were detected in different parts of sheep heads. The mean larval intensity per infected animal with <i>Oestrus ovis</i> was 6.38. In this study, the minimum and maximum numbers of larvae recovered were 1 and 26, respectively. The nasal cavity, nasal sinus and frontal sinus were the predilection sites of <i>Oestrus ovis</i> larvae identified in this study.</p><p><strong>Conclusion: </strong>Oestrosis is an important and common parasitic disease of sheep in the study area.</p>","PeriodicalId":75300,"journal":{"name":"Veterinary medicine (Auckland, N.Z.)","volume":" ","pages":"59-64"},"PeriodicalIF":0.0,"publicationDate":"2022-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/80/82/vmrr-13-59.PMC8857965.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39958772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude, and Practice Toward Pet Contact Associated Zoonosis in Western Ethiopia.","authors":"Yobsan Tamiru,&nbsp;Debela Abdeta,&nbsp;Morka Amante","doi":"10.2147/VMRR.S346806","DOIUrl":"https://doi.org/10.2147/VMRR.S346806","url":null,"abstract":"<p><strong>Background: </strong>Households consider their dogs and cats as their close friends. They act as companion animals. The contact between pets and their owners results in transmission of zoonotic disease. In Ethiopia, dogs and cats are the most abundant carnivores, and diseases associated with them affect wide parts of the community. There is limited knowledge, practice, and attitude within the communities toward pet contact associated zoonotic disease.</p><p><strong>Methods: </strong>A community-based semi-structured questionnaire complemented with an interview was delivered to 633 household pets' owners in Sibu Sire, Jimaa Arjo, and Wayu Tuqa districts in Western Ethiopia to evaluate knowledge, attitude, and practices toward pet contact associated zoonotic disease.</p><p><strong>Results: </strong>Socio-demographically, 54.6% of the study participants were female. According to this finding concerning common pet contact zoonotic disease, 70% of the respondents had knowledge about rabies, with Echinococcosis, toxoplasmosis, and ring worm also being commonly heard of. Contamination of feed and water (21.71%) and animal bites (21.01%) are the predominant modes of transmission, whereas animal waste, fecal oral route, and touching pets are also common ways for disseminating zoonotic disease. The dominant symptoms noted by respondents were behavioral change, depression, lack of appetite, itching, and diarrhea. In all attitude-related responses, there was a significant association (p<0.05) between the number of respondents and the variable studied. There was also a statistically significant association of KAP score (p<0.05) with educational rank and the work of respondents.</p><p><strong>Conclusion: </strong>This study indicates the importance of pet ownership to the community, which is also associated with transmitting different zoonotic diseases. Moreover, there are inconsistencies on regular veterinary use, pet management, and proper prevention and treatment measures of the disease. Coordinated efforts are expected from different stakeholders in enhancing community KAP level towards pet contact associated zoonosis.</p>","PeriodicalId":75300,"journal":{"name":"Veterinary medicine (Auckland, N.Z.)","volume":" ","pages":"47-58"},"PeriodicalIF":0.0,"publicationDate":"2022-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/05/da/vmrr-13-47.PMC8819162.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39601364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprevalence and Associated Risk Factors of Infectious Bursal Disease in Chickens Managed Under Intensive and Backyard Production Systems in Western Oromia, Ethiopia.","authors":"Debela Abdeta,&nbsp;Yobsan Tamiru,&nbsp;Morka Amante,&nbsp;Dereje Abebe,&nbsp;Felmeta Kenei,&nbsp;Jirata Shiferaw,&nbsp;Misgana Tefera","doi":"10.2147/VMRR.S347373","DOIUrl":"https://doi.org/10.2147/VMRR.S347373","url":null,"abstract":"<p><strong>Background: </strong>Infectious bursal disease (IBD) is a highly contagious viral disease challenging poultry industry throughout the world. It is also among the main obstacles in the different chicken production system in Ethiopia. This study was conducted with the aim of determining seroprevalence and associated risk factors of IBD in backyard and intensively managed chickens of the study area.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in selected districts of western Oromia on intensive and backyard production systems to investigate seroprevalence of IBD and associated risk factors from September 2020 to August 2021. A total of 384 chickens of either sex, 128 from each district, were included from three randomly selected peasant associations (PAs). In addition, 180 individual poultry keepers, of both sexes, and different educational backgrounds, were included for questionnaire survey (Supplementary Material). Data were analyzed using SPSS Version-20, and results were presented as percentages. The samples were processed by using (ProFLOKIBV, USA) indirect enzyme-linked immunosorbent assay (I-ELISA) kits.</p><p><strong>Results: </strong>Out of 384 serum samples tested, 66.93% (<i>n</i> = 257) were found positive by indirect ELISA. The highest prevalence was recorded from Sasiga district Balo Bareda PA. Prevalence of IBD showed significant statistical association (<i>p</i> < 0.05) among owner education level, chicken rearing practice, origin and breed. Questionnaire survey results showed the majority of respondents lack sufficient knowledge about IBD and other chicken diseases. The practice of backyard chicken producers on vaccination and treatment of sick birds is limited.</p><p><strong>Conclusion: </strong>In conclusion, IBD is a major factor hindering production and health of birds. Proper vaccination programs coordinated with awareness creation of chicken owners on how to isolate and treat sick birds should be implemented.</p>","PeriodicalId":75300,"journal":{"name":"Veterinary medicine (Auckland, N.Z.)","volume":" ","pages":"39-46"},"PeriodicalIF":0.0,"publicationDate":"2022-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ec/fb/vmrr-13-39.PMC8800864.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39590042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Immunogenicity Evaluation of Two Infectious Bursal Disease Vaccines Commonly Used in Broiler Chickens in Ethiopia.","authors":"Likelesh Legese,&nbsp;Berhane Wakjira,&nbsp;Tsedale Teshome,&nbsp;Dereje Nigussie Woldemichael,&nbsp;Hika Waktole,&nbsp;Fikru Regassa,&nbsp;Takele Beyene Tufa","doi":"10.2147/VMRR.S346659","DOIUrl":"https://doi.org/10.2147/VMRR.S346659","url":null,"abstract":"<p><strong>Purpose: </strong>Infectious bursal disease (IBD) is one of the most endemic diseases of commercial poultry in Ethiopia. Vaccination is used as the major means of IBD prevention and control. A study was conducted to compare the immunogenicity of two commercially available IBD vaccines in broiler chicken with maternally derived antibody (MDA).</p><p><strong>Methods: </strong>A total of 270 day-one-old chicks were randomly assigned to three groups, group 1 vaccinated with product A vaccine at the age of 7 and 19 days and group 2 with product B vaccine on day 15 and 22 while group 3 were kept as control. Six chickens were also randomly selected and bled on day 1 for differential leukocyte count (DLC) and determination of MDA. Representative chickens from each group were bled at 24th and 42nd days of age for antibody titration using the indirect ELISA test. DLC scores were determined in the 1st and 24th days.</p><p><strong>Results: </strong>The result revealed highly significant differences (<i>P</i> = 0.001) between group 1 and group 2 in DLC at 24th days of age. Antibody titers against IBD were differed significantly (<i>P</i> = 0.02) at 24th and 42nd days of age in broilers vaccinated with product A and product B vaccines.</p><p><strong>Conclusion: </strong>Both vaccines have induced an adequate immunological response at the end of the experiment; however, product A has shown significantly higher antibody titers against the IBDV and DLC than product B.</p>","PeriodicalId":75300,"journal":{"name":"Veterinary medicine (Auckland, N.Z.)","volume":" ","pages":"31-38"},"PeriodicalIF":0.0,"publicationDate":"2022-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/d8/vmrr-13-31.PMC8784269.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39862138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}