Vertex (Buenos Aires, Argentina)最新文献_第9页

Índice. 指数

Vertex (Buenos Aires, Argentina) Pub Date : 2023-10-10

Comité de Redacción

引用次数: 0

Embotional Blunting or apathy by SSRI? A sistematic review about their emotional effects 对SSRI的冷漠或情感迟钝？文献回顾。

Vertex (Buenos Aires, Argentina) Pub Date : 2023-10-10 DOI: 10.53680/vertex.v34i161.486

Gonzalo Emmanuel Barbosa Eyler

{"title":"Embotional Blunting or apathy by SSRI? A sistematic review about their emotional effects","authors":"Gonzalo Emmanuel Barbosa Eyler","doi":"10.53680/vertex.v34i161.486","DOIUrl":"10.53680/vertex.v34i161.486","url":null,"abstract":"Introduction: Selective Serotonin Reuptake Inhibitors (SSRIs) are a group of antidepressants that have revolutionized the psychopharmacological therapeutic field since their appearance. They are in the first line of recommendation for\u0000the treatment of anxiety disorders and major depressive disorder. And although they are better tolerated and have a better side effect profile than the classic ones, they are not exempt from them. Among the adverse effects of SSRIs little considered by health professionals, are apathy or mental dullness. Restrictions of the range of emotions that are related to normal life, such as the ability to cry or feel pleasure, have been reported. This phenomenon has been called variously in the literature, such as emotional blunting, apathy, emotional indifference, or decreased sensitivity or emotional response.Objectives: The aim of this review is to analyze the emotional effects of SSRI that are described in the literature.Methods: A bibliographic review of the literature published in Pubmed from 2006 to 2021 was carried out, with the words Mesh \"SSRI\" and \"Apathy\" and \"emotional blunting\".Results: Literature reports indicate that the mental dullness produced by SSRIs is generated in at least 50 % of the patients who receive them, with different intensities between them.Conclusions: Although effects of emotional blunting or apathy have been reported with various groups of antidepressants, all reports agree that it occurs more frequently in patients taking SSRIs than with other antidepressants.","PeriodicalId":75297,"journal":{"name":"Vertex (Buenos Aires, Argentina)","volume":"34 161, jul.-sept.","pages":"61-66"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41223025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unified Protocol for the transdiagnostic treatment of emotional disorders in virtual and group format in Argentina: three months follow-up of a pilot study 阿根廷虚拟和团体形式情感障碍转诊治疗的统一协议：一项试点研究的三个月随访。

Vertex (Buenos Aires, Argentina) Pub Date : 2023-10-10 DOI: 10.53680/vertex.v34i161.482

Milagros Celleri, Camila Florencia Cremades, Lautaro Rojas, Cristian Javier Garay

{"title":"Unified Protocol for the transdiagnostic treatment of emotional disorders in virtual and group format in Argentina: three months follow-up of a pilot study","authors":"Milagros Celleri, Camila Florencia Cremades, Lautaro Rojas, Cristian Javier Garay","doi":"10.53680/vertex.v34i161.482","DOIUrl":"10.53680/vertex.v34i161.482","url":null,"abstract":"Introduction: The Unified Protocol (UP) is a psychotherapeutic intervention that has proven to be effective for the transdiagnostic treatment of emotional disorders, both in individual and group format. Recently, its virtual application through teletherapy has begun to be studied. In a previous pilot study carried out in Argentina in a sample of 7 subjects, significant decreases were observed in levels of depression, difficulties in emotional regulation, hopelessness and negative affect and a significant increase in quality of life after having applied the PU in virtual and group format to people with emotional disorders.Method: The present work aims to evaluate the maintenance of the results observed in this study after three\u0000months.Results: No statistically significant differences were observed in any of the variables analyzed, which shows that the results achieved have been maintained.Discussion: The UP is presented as a promising intervention for the treatment of emotional disorders in a virtual and group format, although further research is required in order to generalize the results.","PeriodicalId":75297,"journal":{"name":"Vertex (Buenos Aires, Argentina)","volume":"34 161, jul.-sept.","pages":"18-23"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41223029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment-Resistant Depression in Argentina: results from a longitudinal analysis of the TRAL Study 阿根廷抗药性抑郁症：TRAL研究纵向分析的结果。

Vertex (Buenos Aires, Argentina) Pub Date : 2023-10-10 DOI: 10.53680/vertex.v34i161.484

Christian Lupo, Gerardo García Bonetto, Ricardo Marcelo Corral, Manuel Vilapriño Duprat, Hernán Alessandria, Gabriela Kanevsky, Sergio Perocco

{"title":"Treatment-Resistant Depression in Argentina: results from a longitudinal analysis of the TRAL Study","authors":"Christian Lupo, Gerardo García Bonetto, Ricardo Marcelo Corral, Manuel Vilapriño Duprat, Hernán Alessandria, Gabriela Kanevsky, Sergio Perocco","doi":"10.53680/vertex.v34i161.484","DOIUrl":"10.53680/vertex.v34i161.484","url":null,"abstract":"Literature concerning patients with Treatment-Resistant Depression (TRD) treatment response and patient report outcomes (PROs) -such as QoL or disability- in Argentina is scarce. In the scope of the Treatment-Resistant Depression in America Latina (TRAL) study which previous results highlighted the burden of TRD compared to non-TRD patients as well as essential epidemiological data in the region, this paper reports on the outcomes of Standard-of-Care (SOC) over a 1-year follow-up of TRD patients in the subsample for Argentina. From a sample of 220 MDD patients identified in 5\u0000sites in Argentina, 72 patients were diagnosed with TRD. Exclusion criteria included patients with psychosis, schizophrenia, bipolar disorder, schizoaffective disorder, dementia, with severe chemical dependence or currently participating in another clinical trial. MADRS, PHQ-9 and PROs (EQ-5D and SDS) were used as outcomes. Patients’ mean age was 54.7 years and 70.3% of the patients were female. Around 61% of the patients achieved a response (reduction of MADRS score ≥ 50%), but over 33% did not achieve a remission (MADRS total score ≤12). Almost 67% of the patients still felt\u0000anxious/depressed at the end of the study (EQ-5D), while disruption affected patients in diverse areas -71% in work/school, 69.7% in social life/leisure and 66.6% in their family life/personal responsibilities. The burden of TRD is significant in Argentina, and more effort should be put in the implementation of treatment protocols with better outcomes.","PeriodicalId":75297,"journal":{"name":"Vertex (Buenos Aires, Argentina)","volume":"34 161, jul.-sept.","pages":"32-44"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41223026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Late-Onset Psychosis and Phenocopies 晚期精神病和现象学。

Vertex (Buenos Aires, Argentina) Pub Date : 2023-10-10 DOI: 10.53680/vertex.v34i161.487

Juan Ollari, Florencia Deschle, Valeria Rubiño, Romina Blanco, Natalia Ciufia, Walter Delembert

引用次数: 0

Test for abnormal niacin response syndrome in schizophrenia: reclaiming the oral route 诊断为精神分裂症的患者对烟酸反应异常综合征的测试：声称口服。

Vertex (Buenos Aires, Argentina) Pub Date : 2023-10-10 DOI: 10.53680/vertex.v34i161.483

Francisco Carena, Pablo Martino, Cristian F Vera, José Bonet

{"title":"Test for abnormal niacin response syndrome in schizophrenia: reclaiming the oral route","authors":"Francisco Carena, Pablo Martino, Cristian F Vera, José Bonet","doi":"10.53680/vertex.v34i161.483","DOIUrl":"10.53680/vertex.v34i161.483","url":null,"abstract":"Introduction: Although there is an abnormal presentation of Niacin Response Syndrome (ANRS) in schizophrenic patients (SZ) compared to subjects with other psychiatric illnesses and with healthy individuals. However, most of the literature is based on studies that have used tests of niacin topical administration, observing, on the other hand, less scientific production of its oral administration. The objective was to determine the sensitivity of the oral niacin test as a method of detecting ASRN in EZ.Methods: A non-randomized clinical trial was carried out. Two groups were formed, the experimental or SZ, with 21 patients diagnosed with schizophrenia according to DSM-IV-TR SZ or schizoaffective disorder, and the HC group, made up of 20 healthy controls. Both groups were exposed to an oral niacin test and clinical-semiological tools were applied to evaluate the NRS.Results: 90.5% of the SZ group presented ANRS. In contrast, no participant in the HC group presented ANRS (0%).Conclusions: Oral niacin administration was sensitive to the detection of ASRN in schizophrenia. Likewise, ASRN could be a gradual phenomenon and its prevalence could be dose-dependent, being lower the lower the dose of oral niacin used. Further trials with larger and randomized samples will be needed.","PeriodicalId":75297,"journal":{"name":"Vertex (Buenos Aires, Argentina)","volume":"34 161, jul.-sept.","pages":"24-31"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41223030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Third Argentine Consensus statement on management Bipolar Disorders. Section3: Bipolar Disorder in the context of special situations 阿根廷关于管理两极疾病的第三个共识。第三部分：特殊情况下的双极性疾病管理。

Vertex (Buenos Aires, Argentina) Pub Date : 2023-10-10 DOI: 10.53680/vertex.v34i161.488

Marcelo Cetkovich-Bakmas, Andrea Abadi, Sebastián Camino, Gerardo García Bonetto, Luis Herbst, Eliana Marengo, Fernando Torrente, Tomás Maresca, Julián Bustin, Carlos Morra, Ricardo Corral, Daniel Sotelo, Sergio Strejilevich, Julián Pessio, Juan José Vilapriño, Manuel Vilapriño, Gustavo Vázquez, Alejo Corrales

引用次数: 0

Index 指数

Vertex (Buenos Aires, Argentina) Pub Date : 2023-07-24

Comité de Redacción

引用次数: 0

Practical Psychopharmacology 实用心理药理学。

Vertex (Buenos Aires, Argentina) Pub Date : 2023-07-10

Juan Carlos Stagnaro

引用次数: 0

Staff 工作人员

Vertex (Buenos Aires, Argentina) Pub Date : 2023-07-10

Comité de Redacción

引用次数: 0