Aktuelle Urologie最新文献

{"title":"Kommentar.","authors":"","doi":"10.1055/a-2489-7595","DOIUrl":"https://doi.org/10.1055/a-2489-7595","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 1","pages":"16"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of long ureteric strictures with a free peritoneal graft: long-term results.","authors":"Emanuela Trenti, Salvatore Palermo, Carolina D'Elia, Evi Comploj, Christian Ladurner, Christoph Gamper, Stefan Pycha, Margherita Palermo, Armin Pycha","doi":"10.1055/a-2058-7983","DOIUrl":"10.1055/a-2058-7983","url":null,"abstract":"<p><strong>Ziel der studie: </strong>Beschreibung einer neuen Technik zur Rekonstruktion von komplexen Ureterstrikturen unter Verwendung eines freien Peritoneallappens.</p><p><strong>Material und methoden: </strong>Zwischen 2006 und 2021 behandelten wir 11 Patienten mit langen komplexen Harnleiterstrikturen, die in 9 Fällen den mittleren- und in 2 Fällen den proximalen Harnleiter betrafen. Die Länge der Strikturen variierte von 3 bis 12 cm (Mittelwert 7 cm). In drei Fällen handelte es sich um eine retroperitoneale Fibrose nach einem gefäßchirurgischen Eingriff, in zwei Fällen um einen Morbus Ormond, in vier Fällen um eine ausgedehnte Resektion großer Harnleitertumoren, in drei Fällen um wiederholte endoskopische Eingriffe bei Harnsteinen und in einem Fall um eine viermal fehlgeschlagene Pyeloplastik. Der Harnleiter wurde längs gespalten, ein freier Peritoneallappen aus dem nahe gelegenen gesunden Bauchfell entnommen und nach Positionierung eines Harnleiterkatheters als Onlay-Patch mit einer fortlaufenden Naht an der verbleibenden Harnleiterplatte fixiert. Der Ureter wurde zuletzt mit Omentum gedeckt.</p><p><strong>Ergebnisse: </strong>Die Nachbeobachtungszeit reichte von 12 bis 122 (Mittelwert 61,6) Monate. Sieben Patienten waren nach 12, 18, 60, 78, 98, 99 und 122 Monaten (Mittelwert 69,5 Monate) rezidivfrei, ohne Erweiterung des oberen Harntrakts und mit normaler Nierenfunktion. Bei vier Patienten kam es zu einem Rezidiv: Bei einem Patienten wurde das Rezidiv nach 60 Monaten ohne Symptome und mit leichter Hydronephrose festgestellt, ohne dass eine Operation erforderlich war. Bei einem Patienten mit Morbus Ormond trat das Rezidiv 6 Monate nach dem Eingriff symptomlos im distalen Teil des 10 cm langen Omlays auf. Es wurde eine Resektion des stenotischen Segments mit Psoas-Hitch durchgeführt. Bei den beiden anderen Patienten trat 3 und 6 Monate nach dem Eingriff eine Obstruktion unterhalb des rekonstruierten Segments mit Hydronephrose auf, ohne dass die Nierenfunktion beeinträchtigt war. Bei diesen Patienten wurde keine weitere Operation durchgeführt. Die Limitation dieser Studie besteht in der kleinen Studiengröße, die auf die strenge Indikationsstellung zurückzuführen ist.</p><p><strong>Schlussfolgerungen: </strong>Die beschriebene Technik ermöglicht den Erhalt der verbleibenden Gefäßversorgung des Harnleiters und stellt eine praktikable und nützliche Alternative zu Nephrektomie, Ileum-Ureter, Uretero-Uretero-Stomie und Autotransplantation in hochselektierten Fällen dar.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":"65-70"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9627006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AUO-Studienaktivitäten in der Uro-Onkologie.","authors":"","doi":"10.1055/a-2412-7442","DOIUrl":"https://doi.org/10.1055/a-2412-7442","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 1","pages":"26-28"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"S2k-Leitlinie „Harninkontinenz bei geriatrischen Patienten“ – Teil 4: Medikamentöse Therapie.","authors":"Andreas Wiedemann, Klaus Becher, Barbara Bojack, Claudia Drews, Ruth Kirschner-Hermanns","doi":"10.1055/a-2288-2597","DOIUrl":"10.1055/a-2288-2597","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 1","pages":"77-88"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nicht obstruierende Nierenkonkremente: Chirurgische Therapie lindert Schmerzen.","authors":"","doi":"10.1055/a-2321-2397","DOIUrl":"https://doi.org/10.1055/a-2321-2397","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 1","pages":"14-16"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Roboterassistierte Prostatektomie: Prostatagröße beeinflusst Operationsergebnis.","authors":"","doi":"10.1055/a-2321-2325","DOIUrl":"https://doi.org/10.1055/a-2321-2325","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 1","pages":"22-23"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ejaculatio praecox: Benefit durch Botox-A-Injektion in den M. bulbospongiosus?","authors":"","doi":"10.1055/a-2321-2169","DOIUrl":"https://doi.org/10.1055/a-2321-2169","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 1","pages":"12"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enfortumab vedotin as a salvage option as 5th line therapy for metastatic urothelial bladder cancer.","authors":"Melanie Klee, Marie Christine Roesch, Hendrik Eggers, Philipp Ivanyi, Axel S Merseburger, Mario Kramer","doi":"10.1055/a-2148-5799","DOIUrl":"10.1055/a-2148-5799","url":null,"abstract":"<p><p>A 67-year-old female patient with a muscle-invasive, non-metastatic urothelial bladder cancer (UC) (pT2 G3 cN0 cM0) developed metachronous metastases within 6 months after radical cystectomy with ileal conduit urinary diversion. After a good primary response to platinum-based chemotherapy, treatment was switched to the immune checkpoint inhibitor (ICI) pembrolizumab due to progressive disease. Subsequently the patient underwent selective internal radiotherapy (SIRT) of the liver and received vinflunine as well as a re-challenge with pembrolizumab. Two years after the initial diagnosis, rapid disease progression ultimately led to a switch to 5th line therapy with enfortumab vedotin (EV), which had only been approved in the United States at that time. The antibody-drug conjugate was well tolerated by the patient after dose reduction to 1.0 mg/ kg body weight. Simultaneous irradiation of newly occurring precardiac, hepatic and cerebral metastases were necessary. After 10 months of therapy with EV, tumour regression was observed accompanied with good symptom control. The presented case illustrates the efficacy and tolerability of EV in a heavily pre-treated patient with metastatic UC (mUC).</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":"71-76"},"PeriodicalIF":0.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107589973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Cobb's collar … seek and you shall find!]","authors":"Evi Comploj, Christian Ladurner, Armin Pycha","doi":"10.1055/a-2466-6115","DOIUrl":"https://doi.org/10.1055/a-2466-6115","url":null,"abstract":"<p><strong>Purpose: </strong>Cobb's collar, also known as Moormann's ring, is a rare membranous stricture of the bulbar urethra. In contrast to the posterior urethral valve (PUV), Cobb's collar is not connected to the verumontanum. A simultaneous occurrence of PUV and Cobb's collar is even rarer. To the best of our knowledge, we report the third case in the literature of a child with coexistence of PUV and Cobb's collar.</p><p><strong>Case presentation: </strong>We present the case of a 3-year-old boy with a history of recurrent episodes of bladder outlet obstruction with residual urine volumes of up to 800 ml. An outward cystoscopy only revealed a bladder neck with a spastic appearance. A neuropediatric visit was unremarkable; magnetic resonance imaging (MRI) of the brain and spine was negative. After the positioning of a suprapubic catheter, cystoscopy was repeated, and a membranous stricture distal to the external sphincter - also known as Cobb's collar - was diagnosed and incised. After the procedure, the patient was able to urinate with residual volumes ranging from 40-50 ml. However, two weeks later, residual volumes increased again, and a second cystoscopy was performed. In addition to the open Cobb's collar, a PUV was detected, and both were incised with a cold hooked knife.</p><p><strong>Conclusions: </strong>The diagnosis is difficult to make unless the urologist is aware of and actively looks for these rare congenital anomalies of the urethra, which present with variable clinical manifestations and degrees of obstruction.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Operative management of penoscrotal elephantiasis].","authors":"Vahudin Zugor, Mustapha Addali, Benjamin Hager, David Kajaia","doi":"10.1055/a-2442-4858","DOIUrl":"https://doi.org/10.1055/a-2442-4858","url":null,"abstract":"<p><p>Enormous oedema of the male genitals, such as penoscrotal elephantiasis, is a very rare condition. It is usually a result of recurrent inflammation, trauma or malignancy, although the main cause is lymphatic filariasis. Furthermore, it is a challenging condition for both patient as well as the attending healthcare team. By elongation of the lymphatic channels, local oedema is initially created. In the further course, through fibrosis and thus deterioration of the lymphatic drainage, recurrent infections with irreversible elephantiac hard swelling and skin changes are evident. Depending upon the clinical stage, conservative or surgical treatment are suggested. Unfortunately, up to date, no evidence-based therapeutic protocol exists. Interdisciplinary cooperation among doctors, physiotherapists with active cooperation of the patient decide the success of the therapeutic outcome.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142779141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}