The European journal of cardiovascular medicine最新文献

{"title":"Outcome of Interventional Cardiac Catheterization in Infants Weighing Less Than 2500 Grams: A Comparative Study","authors":"A. Afifi, M. El-Baz, H. A. Elghaiaty, A. Fattouh, H. Hamza","doi":"10.5083/ejcm20424884.175","DOIUrl":"https://doi.org/10.5083/ejcm20424884.175","url":null,"abstract":"ABSTRACT\u0000\u0000Objectives: A retrospective study to evaluate the outcome of interventional cardiac catheterization in infants weighing <2500 grams.\u0000\u0000Background: The mortality of small weight infants undergoing heart surgery remains high, so cardiac catheterization has been utilized to improve the outcome.\u0000\u0000Methods: The study included infants who underwent interventional cardiac catheterization within the first 60 days of life in New Children Cairo University Hospital, Cairo, Egypt from January 2015 to January 2018. The study group included infants < 2500 grams while the comparative group included infants ≥ 2500 grams. Adverse events were classified according to the mechanism and seriousness.\u0000\u0000Results: The study group (37 patients) had a mean weight of 2.35 ±0.13 Kg, while the comparative group (164 patients) had a mean weight of 3.54 ±0.71 Kg. The procedures included balloon atrial septostomy, pulmonary balloon valvuloplasty, ductus arteriosus stenting and radiofrequency perforation of pulmonary atresia. The study group showed less success rates as compared with the comparative group (83.8% versus 93.9%, p = 0.04), and higher incidence of overall adverse events (48.6% versus 20.1 %, p<0.001) as well as catheterization-related mortality (29.7% versus 4.9%, P<0.001). In the study group, pulmonary balloon valvuloplasty showed the highest incidence of major adverse events while ductus arteriosus stenting had the highest incidence of mortality.\u0000\u0000Conclusions: Compared to normal weight infants, interventional cardiac catheterization in small weight infants is associated with lower success and higher morbidity and mortality rates. Pulmonary balloon valvuloplasty and ductus arteriosus stenting have the highest morbidity and mortality, respectively.","PeriodicalId":75000,"journal":{"name":"The European journal of cardiovascular medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42291795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Coronary Artery Aneurysm – Report of two cases","authors":"K. Jadhav, K. Raju, R. Reddy, K. Sridhar, S. Ramani, SS Mane","doi":"10.5083/ejcm20424884.174","DOIUrl":"https://doi.org/10.5083/ejcm20424884.174","url":null,"abstract":"Coronary artery aneurysm (CAA) is described as a localized dilatation of a coronary artery segment by more than 1.5-fold compared with the adjacent normal segments. The incidence of CAA varies from 0.3 to 5.3% with atherosclerosis, Takayasu arteritis, congenital disorders, Kawasaki disease, and percutaneous coronary intervention (PCI) being the common etiologic factors. \u0000\u0000Owing to its varying presentation and absence of robust treatment guidelines, management of CAA is a challenge. Management of every patient must be tailored according to the presentation and expertise of the cardiac team available. Here, we present case reports of two patients with CAA who presented with acute coronary syndrome. \u0000\u0000As a result of unstable presentation, both patients underwent immediate intervention (CABG and PCI respectively) with successful revascularization having no complication and mortality.","PeriodicalId":75000,"journal":{"name":"The European journal of cardiovascular medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44722855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Coronary Artery Disease and Metabolic Syndrome in Patients with Acute Coronary Syndrome in South Punjab Region of Pakistan","authors":"G. Niazi, F. Adnan, Saleemi, A. Akhtar, N. Ahmed, ST Shehzad","doi":"10.5083/ejcm20424884.171","DOIUrl":"https://doi.org/10.5083/ejcm20424884.171","url":null,"abstract":"Background: \u0000Hypertension, dyslipidemia, and disturbed glucose metabolism associated with central obesity are often referred to as Metabolic Syndrome (MetS) and patients of MetS have a two- to three-fold increased risk for the development of cardiovascular diseases.\u0000Objective: Objectives were to determine the frequency of MetS in patients presenting with acute coronary syndromes and to compare the frequencies of severe coronary artery disease in patients with and without MetS.\u0000\u0000Methods: \u0000This descriptive cross-sectional study included 200 patients with acute coronary syndromes over a period of six months. Frequency of MetS was calculated. The frequencies of severe coronary artery disease were compared between patients having MetS and not having MetS using chi-square chart.\u0000\u0000Results: \u0000Total 200 patients with the mean age of 54.24 ± 9.41 years were included. 131 (65.5%) patients with acute coronary syndrome had MetS. Total 112 patients (56%) had severe coronary artery disease. 63.35% with MetS and 42.03% without MetS had severe coronary artery disease (p=0.003).\u0000\u0000Conclusion: \u0000The frequency of metabolic syndrome was high (65.5%) in patients with acute coronary syndromes and severe coronary artery disease was found to be associated with the presence of metabolic syndrome in these patients.","PeriodicalId":75000,"journal":{"name":"The European journal of cardiovascular medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48088225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiopulmonary Exercise Testing in Percutaneous Mitral Valve Repair: A Single Centre’s Experience","authors":"K. C. Hou, T. S. Yaw, Y. Keong","doi":"10.5083/ejcm20424884.173","DOIUrl":"https://doi.org/10.5083/ejcm20424884.173","url":null,"abstract":"Chronic severe mitral regurgitation (MR) confers negative hemodynamic consequences and long-term morbidity and mortality1. The adverse remodeling processes result in the inability of mitral valve leaflets to co-apt optimally in functional MR (FMR)2. Even after optimal medical therapy, or revascularization, FMR may not necessarily be reduced adequately. In such patients who remain persistently symptomatic from residual MR, the next course of management may be the surgical or percutaneous intervention of the mitral valve apparatus. Subsequently, percutaneous repair via transcatheter delivered systems has emerged as the treatment of choice; especially, in patients assessed to be at a high operative risk with a suitable anatomy for minimally invasive approaches to re-appose the mitral leaflets3. This has also revolutionized the approach to the management of primary mitral regurgitation (PMR), such as from mitral valve prolapse. It was treated conventionally by the surgical intervention with mitral valve repair or replacement, allowing an alternative option for the high surgical risk patients 4.\u0000\u0000In our center, the transcatheter mitral valve repair procedure (MitraClip) has been introduced in the year 2012, providing an option of percutaneous intervention to the patients where MR is unsuitable for the surgical correction. However, persistent symptoms may occur due to the concomitant non-valvular or non-cardiac pathologies, particularly chronic pulmonary diseases. Also, assessment of functional class is subjective and may be confounded by other variables, such as sedentary lifestyle, self-imposed exercise restrictions, or orthopedic conditions.\u0000\u0000The cardiopulmonary exercise test (CPET) provides an objective assessment of the exercise capacity, obviating the subjective aspects of self-reported symptoms and functional status Besides, CPET is also useful to discern pulmonary and functional status. \u0000\u0000Besides, CPET is also useful to discern pulmonary and non-cardiac contributory components of the perceived decreased functional capacity, including motivational factors.\u0000\u0000Multiple CPET parameters, related to hemodynamic surrogates before and after the MitraClip procedure, also enable a more objective evaluation of the cardiovascular impact of the repair, allowing insights into the improvements in cardiac hemodynamics post intervention7-10.","PeriodicalId":75000,"journal":{"name":"The European journal of cardiovascular medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44003281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Coronary Artery Disease and Metabolic Syndrome in Patients with Acute Coronary Syndrome","authors":"Gul Zaman Khan Niazi, Syed Tahseen Shehzad, A. Akhtar, M. S. Saleemi","doi":"10.5083/ejcm20424884.17","DOIUrl":"https://doi.org/10.5083/ejcm20424884.17","url":null,"abstract":"","PeriodicalId":75000,"journal":{"name":"The European journal of cardiovascular medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43659207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Permanent Complete Heart Block After Kaala Pathar (Paraphenylene Diamine) Poisoning: A Case Report","authors":"S. Saleemi, A. Akhtar","doi":"10.5083/ejcm20424884.172","DOIUrl":"https://doi.org/10.5083/ejcm20424884.172","url":null,"abstract":"Kaala Patthar, containing paraphenylene diamine (PPD) chemically, is used as a hair dye in South Punjab. Recent trends have shown its increasing use as a poison. The common manifestations of Kala Patthar poisoning include upper airway edema, rhabdomyolysis, and acute renal shutdown. However, cardiac toxicity is a rare complication and the conduction abnormalities are seldom reported. We are going to report a case of permanent complete heart block after Kaala Patthar poisoning where the patient needed permanent pacemaker to save his life.","PeriodicalId":75000,"journal":{"name":"The European journal of cardiovascular medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48386249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Breast Arterial Calcification Presence and Gradation with the Ankle-Brachial Index among Postmenopausal Women.","authors":"Carlos Iribarren, Gabriela Sanchez, Meng Lu, Fatemeh Azamian Bidgoli, Hyo-Min Cho, Huanjun Ding, Sabee Molloi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To examine the association of breast arterial calcification (BAC) with the ankle brachial index (ABI), a sensitive metric of peripheral arterial disease (PAD), among postmenopausal women. Background: BAC is an emerging risk marker of cardiovascular disease (CVD).</p><p><strong>Methods: </strong>MINERVA (MultIethNic study of brEast aRterial calcium gradation and cardioVAscular disease) is a cohort of women aged 60 to 79 at baseline (10/24/2012 - 2/13/2015) who were free of symptomatic CVD at baseline. The analytical sample comprised 3,800 women with available ABI, BAC assessment and covariates. We performed cross-sectional logistic regression analysis.</p><p><strong>Results: </strong>203 women (5.3%) had an ABI < 0.90 indicative of PAD, 26 (0.7%) had an ABI > 1.3 and 94% (n=3,571) had an ABI within normal limits. After adjustment for age, race/ethnicity, body mass index, smoking status, diabetes, hypertension, LDL-C, HDL-C, hs-CRP, estimated-GFR, urinary albumin/creatinine ratio, serum calcium, serum vitamin D and serum PTH, BAC presence remained significantly associated with ABI < 0.90 (OR=1.37; 95% CI, 1.01-1.87; p=0.04). After further adjustment for menopausal hormone therapy, parity and history of breast feeding, the association became marginally significant (OR=1.36; 95% CI, 0.99-1.85; p=0.05). No clear pattern of association was observed for increased gradation of BAC and ABI<0.9, and no significant associations were noted between BAC presence vs. absence or BAC gradation with ABI > 1.3.</p><p><strong>Conclusions: </strong>Among asymptomatic postmenopausal women, presence of BAC was associated with PAD independently of traditional risk factors. Additional prospective studies are required to establish the value of BAC for prediction of incident PAD in the general population.</p>","PeriodicalId":75000,"journal":{"name":"The European journal of cardiovascular medicine","volume":"5 5","pages":"544-551"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385879/pdf/nihms-997891.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10444805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The safety and Efficacy of smoking cessation treatments","authors":"M. Eisenberg","doi":"10.5083//ejcm.20424884.154","DOIUrl":"https://doi.org/10.5083//ejcm.20424884.154","url":null,"abstract":"","PeriodicalId":75000,"journal":{"name":"The European journal of cardiovascular medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47937354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refining the Enrolment Process in Emergency Medicine Research.","authors":"Kate M Sahan, Keith M Channon, Robin P Choudhury, Rajesh K Kharbanda, Regent Lee, Mark Sheehan","doi":"10.5083/ejcm.20424884.147","DOIUrl":"10.5083/ejcm.20424884.147","url":null,"abstract":"<p><p>Research in the emergency setting involving patients with acute clinical conditions is needed if there are to be advances in diagnosis and treatment. But research in these areas poses ethical and practical challenges. One of these is the general inability to obtain informed consent due to the patient's lack of mental capacity and insufficient time to contact legal representatives. Regulatory frameworks which allow this research to proceed with a consent 'waiver', provided patients lack mental capacity, miss important ethical subtleties. One of these is the varying nature of mental capacity among emergency medicine patients. Not only is their capacity variable and often unclear, but some patients are also likely to be able to engage with the researcher and the context to varying degrees. In this paper we describe the key elements of a novel enrolment process for emergency medicine research that refines the consent waiver and fully engages with the ethical rationale for consent and, in this context, its waiver. The process is verbal but independently documented during the 'emergent' stages of the research. It provides appropriate engagement with the patient, is context-sensitive and better addresses ethical subtleties. In line with regulation, full written consent for on-going participation in the research is obtained once the emergency is passed.</p>","PeriodicalId":75000,"journal":{"name":"The European journal of cardiovascular medicine","volume":"4 1","pages":"506-510"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975512/pdf/emss-68476.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34642905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using The Descending Aortic Wall Thickness Measured In Transesophageal Echocardiography As A Risk Marker For Aortic Dissection.","authors":"Zaher Fanari,&nbsp;Sumaya Hammami,&nbsp;Muhammad Baraa Hammami,&nbsp;Safa Hammami,&nbsp;Chete Eze-Nliam,&nbsp;William S Weintraub","doi":"10.5083/ejcm.20424884.136","DOIUrl":"https://doi.org/10.5083/ejcm.20424884.136","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to estimate whether aortic wall thickness is increased in patients with Aortic dissection (AD) compared to low risk control group and can be used in addition to aortic diameter as a risk marker of AD.</p><p><strong>Background: </strong>AD occurs due to pathologies that may increase thickness of the aortic wall. Transesophageal echocardiography (TEE) has the ability to visualize both the thoracic aortic wall and lumen. Aortic diameter has been used to predict aortic dissection and timing of surgery, but it is not always predictive of that risk.</p><p><strong>Methods: </strong>In 48 patients with AD who underwent TEE were examined retrospectively and compared to 48 control patients with patent foramen ovale (PFO). We measured aortic diameter at different levels, intimal/medial thickness (IMT) and complete wall thickness (CMT). Demographic data and cardiovascular risk factors were reviewed. The data was analyzed using ANOVA and student t test.</p><p><strong>Results: </strong>(AD) patients were older [mean age 66 AD vs. 51 PFO], had more hypertension, diabetes, hyperlipidemia and Coronary artery disease. Both IMT and CMT in the descending aorta were increased in AD group [(1.85 vs. 1.43 mm; P=0.03 and 2.93 vs. 2.46 mm; p=0.01). As expected the diameter of ascending aorta was also greater in AD (4.61 vs. 2.92 cm; P=0.004).</p><p><strong>Conclusions: </strong>CMT and IMT in the descending aorta detected by TEE is greater in patients with AD when compared to control and may add prognostic data to that of aortic diameter.</p>","PeriodicalId":75000,"journal":{"name":"The European journal of cardiovascular medicine","volume":"3 1","pages":"448-451"},"PeriodicalIF":0.0,"publicationDate":"2015-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429792/pdf/nihms687080.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33187148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}