The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology最新文献

{"title":"Feasibility and safety of coronary catheter rolling technique (Jahanzeb technique) for radial artery catheterization on arterial perforation and radial artery patency.","authors":"Wahab Anwar, Ali Karim, Mubeena Javed, Poonam Kumari, Daya Kumari, F N U Karishma, Muhammad Salman, Hesham Naeem, Abida Perveen, Jahanzeb Malik","doi":"10.1186/s43044-026-00751-6","DOIUrl":"10.1186/s43044-026-00751-6","url":null,"abstract":"<p><strong>Background: </strong>Transradial access is widely used for coronary angiography and percutaneous coronary intervention (PCI); however, complications such as radial artery spasm, perforation, and occlusion remain clinically relevant. Jahanzeb's Coronary Catheter Rolling Technique (JCRT) is a novel method designed to improve catheter navigation and reduce vascular trauma.</p><p><strong>Objective: </strong>To evaluate the feasibility, safety and clinical outcomes of JCRT compared with the conventional radial catheterization technique.</p><p><strong>Methods: </strong>In this prospective, non-randomized comparative study 4,697 patients undergoing elective coronary angiography or PCI via radial access were included. Patients were allocated to JCRT (n = 1,519) or the standard technique (n = 3,178). Primary endpoints were arterial perforation and radial artery occlusion. Secondary endpoints included major bleeding, radial artery spasm, thrombosis, and patient and physician satisfaction. Outcomes were analyzed using odds ratios (OR) with 95% confidence intervals (CI) and multivariable logistic regression was performed.</p><p><strong>Results: </strong>JCRT was associated with a significantly lower overall complication rate (7.6% vs. 11.0%; OR: 0.66, 95% CI 0.52-0.92; p = 0.037). Significant reductions were observed in major bleeding (4.3% vs. 7.1%; OR: 0.58, 95% CI 0.42-0.81; p = 0.024), radial artery spasm (2.1% vs. 4.9%; OR: 0.41, 95% CI 0.27-0.63; p = 0.011), arterial perforation (1.6% vs. 3.8%; OR: 0.41, 95% CI 0.24-0.71; p = 0.032), and radial artery occlusion (2.8% vs. 6.3%; OR: 0.43, 95% CI 0.29-0.63; p = 0.006). On multivariable analysis, JCRT remained associated with reduced complications after adjustment (adjusted OR: 0.69, 95% CI: 0.51-0.93; p = 0.021). Patient and physician satisfaction scores were significantly higher with JCRT (p < 0.001).</p><p><strong>Conclusion: </strong>JCRT is a feasible and safe technique associated with reduced vascular complications and improved satisfaction. Further multicenter randomized studies are warranted to confirm these findings.</p>","PeriodicalId":74993,"journal":{"name":"The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13280300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OMI: time for early recognition and management of acute coronary occlusion.","authors":"Grigorios Avdikos, Stephen W Smith","doi":"10.1186/s43044-026-00759-y","DOIUrl":"10.1186/s43044-026-00759-y","url":null,"abstract":"","PeriodicalId":74993,"journal":{"name":"The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13275967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148267474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes in provisional one-stent versus dedicated two-stent coronary bifurcation stenting techniques: a systematic review and meta-analysis.","authors":"Harsh Agrawal, Pooja Dubey, Jay Tewari, Shubhechha Neupane, Vanshika Singh, Kendrick Shunk, Muditha Perera, Alok Kumar Dwivedi, Debabrata Mukherjee","doi":"10.1186/s43044-026-00757-0","DOIUrl":"10.1186/s43044-026-00757-0","url":null,"abstract":"<p><strong>Background: </strong>The optimal long-term strategy for coronary bifurcation PCI remains debated. Earlier meta-analyses limited to long-term data suggested better outcomes with a provisional approach versus routine two-stent techniques.</p><p><strong>Methods: </strong>We conducted an updated, comprehensive meta-analysis of randomized controlled trials comparing provisional versus two-stent strategies. MEDLINE, Embase, and the Cochrane Library were searched through September 2025. Fifteen RCTs (n = 6978) met inclusion criteria. Using Stata 16.1, random-effects (DerSimonian-Laird) risk ratios (RRs) with 95% confidence intervals (CIs) were calculated for prespecified outcomes.</p><p><strong>Results: </strong>Relative risks (95% CIs) for provisional vs two-stent were: all-cause mortality 0.97 (0.72-1.30); cardiovascular mortality 0.98 (0.68-1.40); myocardial infarction 0.86 (0.62-1.19); target lesion revascularization 1.07 (0.80-1.44); stent thrombosis 1.36 (0.81-2.29); and MACE 1.27 (0.81-1.99). Across endpoints, pooled estimates did not show statistically significant differences between strategies.</p><p><strong>Conclusion: </strong>In this updated synthesis of randomized trials, the available evidence did not demonstrate clear superiority of either provisional or two-stent strategies for major clinical outcomes. Unlike prior long-term-only analyses, we did not observe higher mortality or myocardial infarction with two-stent approaches. Technique selection should remain individualized according to lesion anatomy, procedural complexity, and operator expertise. These findings should not be interpreted as proof of equivalence or non-inferiority. Trial registration CRD420251167534.</p>","PeriodicalId":74993,"journal":{"name":"The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13272726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148260708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence in the clinical management and prognostication of mitral regurgitation: a systematic review.","authors":"Armia Ahmadi-Hadad, Michela Belotti, Assil Zennoud, Boshra Moghimi, Caterina Autuori, Divinie Sumanasekara, Hashini Maneesha Fernando Udiriappuwaduge, Giuseppe Comentale, Emanuele Pilato","doi":"10.1186/s43044-026-00756-1","DOIUrl":"10.1186/s43044-026-00756-1","url":null,"abstract":"<p><strong>Background: </strong>Mitral regurgitation (MR), one of the most common valvular heart diseases, poses ongoing challenges in risk stratification and timely intervention. Traditional diagnostic approaches, suffer from interobserver variability. Artificial intelligence (AI) has recently gained traction in cardiology to augment clinical precision. This article reviews the use of AI in the diagnosis, severity assessment, and prognostication of MR, with a focus on performance metrics.</p><p><strong>Methods: </strong>The search was conducted in PubMed, Embase, and MEDLINE on May 9, 2025. Studies were eligible if they applied AI to MR-related tasks using imaging, ECG, or clinical data. Data extraction focused on dataset characteristics, model architectures, and performance.</p><p><strong>Results: </strong>A total of eleven studies, comprising 80,915 patients, were included. Among the included studies, six utilized echocardiographic data, two electrocardiography, two clinical biomarkers or structured datasets, and one chest radiography. Algorithms included convolutional neural networks, support vector machines, and ensemble models. Reported AUCs ranged from 0.74 to 0.94. Models based on color Doppler or 3D geometrical mitral features achieved the highest discriminatory performance. Only a minority of studies incorporated external validation or reported clinically actionable thresholds such as PPV. ECG-based models demonstrated high scalability but lower sensitivity. Studies integrating multimodal data yielded promising results.</p><p><strong>Conclusion: </strong>AI models, especially those trained on echocardiographic imaging, demonstrate strong potential for improving MR evaluation. However, widespread clinical adoption is limited by lack of external validation, and inconsistent outcome reporting. Future work should emphasize model interpretability, multicenter validation, and head-to-head comparisons with expert assessment to bridge the translational gap.</p>","PeriodicalId":74993,"journal":{"name":"The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13260502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148220813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Difference in outcomes between right and left posterior descending artery percutaneous coronary intervention: an Australian statewide registry analysis.","authors":"Muhtasim Rahman Zahin, Riley Batchelor, Angela Brennan, Diem Dinh, Christopher Reid, Dion Stub, Jeffrey Lefkovits","doi":"10.1186/s43044-026-00755-2","DOIUrl":"10.1186/s43044-026-00755-2","url":null,"abstract":"<p><strong>Introduction: </strong>Percutaneous coronary intervention (PCI) is an important treatment for coronary artery disease, and coronary dominance may influence procedural risk. PCI to a left-sided posterior descending artery (L-PDA) occurs in the setting of left-dominant coronary anatomy and may involve greater anatomical complexity and a larger myocardial territory at risk than PCI to a right-sided PDA (R-PDA). We performed a retrospective analysis of a statewide registry to compare the characteristics and outcomes of R-PDA and L-PDA PCI.</p><p><strong>Methods: </strong>The Victorian Cardiac Outcomes Registry is a state-wide quality registry with all PCI capable centres in Victoria, Australia contributing. We undertook a retrospective analysis of patients undergoing PCI for L-PDA and R-PDA lesions between 2013 and 2022.</p><p><strong>Results: </strong>2,880 patients were included over the 10-year study period, with 2,282 (79.2%) undergoing R-PDA PCI and 598 (20.8%) undergoing L-PDA PCI. Patient characteristics between groups were of similar age (66.3 years in both groups), gender (17.9% vs. 14.5%; p = 0.06) and had comparable rates of comorbidities including diabetes (25.8% vs. 24.9%; p = 0.66). There was no significant difference between groups with respect to 30-day mortality (1.1% vs. 0.5%; p = 0.21). 30-day MACE was also comparable (2.2% both groups; p = 0.93).</p><p><strong>Conclusions: </strong>Data from a large contemporary cohort did not find any association between coronary dominance and clinical outcomes when undertaking PDA PCI.</p>","PeriodicalId":74993,"journal":{"name":"The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13247022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endovascular ablation of the right greater splanchnic nerve for the management of heart failure with preserved ejection fraction: a systematic review and meta-analysis.","authors":"Hashim Manea, Mostafa A Khalifa, Mustafa A Shahrori, Aya Ahmed Shimal, Ahmad Omar Saleh, Omnia Samy El-Sayed, Muhammad Bashir, Elian Khalafalla Awadalla, Alaa R Al-Ihribat, Fathimathul Henna, Mohammedbaqer Al-Ghuraibawi, Mohammad Amjad Shahrori","doi":"10.1186/s43044-026-00748-1","DOIUrl":"10.1186/s43044-026-00748-1","url":null,"abstract":"<p><strong>Background: </strong>Heart failure with preserved ejection fraction (HFpEF) remains difficult to manage because conventional therapies often provide limited symptom relief and do not adequately address exercise-related congestion. Right greater splanchnic nerve (GSN) ablation has emerged as a potential therapeutic approach by modulating splanchnic venous capacitance. However, current evidence is limited and includes both uncontrolled and randomized studies.</p><p><strong>Methods: </strong>We performed a systematic review and meta-analysis of studies evaluating right GSN ablation in HFpEF. Searches were conducted in PubMed, Scopus, and Embase in December 2024. Randomized and non-randomized studies were included. Continuous outcomes were pooled as mean differences (MDs) with 95% confidence intervals (CIs). Sensitivity analyses excluding the randomized controlled trial (RCT) were performed for selected outcomes. Analyses based on uncontrolled studies and converted median/interquartile range data were considered exploratory.</p><p><strong>Results: </strong>The most consistent findings were observed in functional and exercise-related hemodynamic outcomes. Six-minute walk distance improved at both 6 and 12 months, and KCCQ overall score showed improvement, although with substantial heterogeneity. Provocative hemodynamic measures, including 20 W and peak pulmonary capillary wedge pressure, were reduced at 1 month, whereas resting hemodynamic measures showed no clear pooled benefit. NT-proBNP, renal indices, blood pressure, heart rate, and left ventricular ejection fraction were largely unchanged. Overall, randomized sham-controlled evidence did not demonstrate a clear comparative benefit.</p><p><strong>Conclusions: </strong>Right GSN ablation may improve selected exercise-related hemodynamic, functional, and patient-reported outcomes in HFpEF, but the current evidence base is driven mainly by small uncontrolled studies. Randomized evidence remains neutral, and further sham-controlled trials are required.</p>","PeriodicalId":74993,"journal":{"name":"The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13246998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148201414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful conservative treatment of MRSA-associated infective endocarditis with concurrent candidemia in a hemodialysis patient.","authors":"Ömer Faruk Yilmaz, Oğuzhan Dilek, Ömer Kutsi Misirlioğlu, Tuba Bozoklu, Havva Tünay, Serkan Gökaslan, Neşe Demirtürk","doi":"10.1186/s43044-026-00754-3","DOIUrl":"10.1186/s43044-026-00754-3","url":null,"abstract":"<p><strong>Background: </strong>Infective endocarditis carries high mortality in hemodialysis patients, particularly when caused by methicillin‑resistant Staphylococcus aureus. Concomitant fungemia further worsens prognosis but remains rare. A 52‑year‑old woman with type 2 diabetes mellitus and stage V chronic kidney disease on thrice‑weekly hemodialysis presented with atypical chest pain, fatigue, night sweats, and splinter hemorrhages. She was afebrile. Transthoracic echocardiography showed preserved left‑ventricular ejection fraction and grade II mitral/tricuspid regurgitation; transesophageal echocardiography revealed a 0.7 × 2.1 cm pedunculated vegetation on the septal leaflet of the tricuspid valve. Three sets of peripheral and catheter blood cultures were drawn, and empiric renally adjusted daptomycin plus gentamicin were started. On day 3, C‑reactive protein had fallen. Cultures grew methicillin‑resistant Staphylococcus aureus in two peripheral sets and in the tunneled catheter, and Candida tropicalis in one peripheral set. The infected catheter was removed and a brachio‑axillary graft was placed. Gentamicin was discontinued; daptomycin was continued for six weeks. Voriconazole was administered for 21 days, ending 14 days after negative fungal cultures. Follow‑up echocardiography at week 6 showed complete resolution of the vegetation. The patient remained asymptomatic at three‑month follow‑up.</p><p><strong>Conclusion: </strong>In immunocompromised hemodialysis patients, dual bacterial‑fungal bloodstream infections can occur, yet not every positive fungal culture indicates endocardial involvement. Serial cultures, prompt removal of infected hardware, and targeted antimicrobial therapy can achieve cure without surgery even in the presence of sizable vegetations.</p>","PeriodicalId":74993,"journal":{"name":"The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13234089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148159331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter ventricular septal defect closure in children: ten-year experience with multiple devices and long-term outcomes.","authors":"Gamze Vuran, Murat Muhtar Yılmazer, Mertkan Bilen, Cem Doğan, Yusuf İlker Dur, Ozan Hira, Aykut Özön, Ömer Faruk Gülaştı, Mustafa Karaçelik, Timur Meşe","doi":"10.1186/s43044-026-00753-4","DOIUrl":"10.1186/s43044-026-00753-4","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter closure has become a widely accepted alternative to surgery for VSD, but long-term pediatric data are limited. This study evaluated procedural success, complications, and long-term outcomes with different occluders.</p><p><strong>Methods: </strong>We retrospectively analyzed 118 children who underwent attempted transcatheter VSD closure between 2014 and 2024, with clinical, echocardiographic, and electrocardiographic follow-up.</p><p><strong>Results: </strong>Closure was successful in 110 patients (93%). Failures were due to multifenestrated anatomy, embolization, residual shunt, atrioventricular (AV) block, tricuspid regurgitation, or insufficient aortic rim. Major complications occurred in six patients, including device embolization, progressive aortic regurgitation requiring surgery, persistent nodal rhythm requiring device removal, ventricular perforation, infective endocarditis, and subarachnoid hemorrhage. Minor complications included mild to moderate tricuspid regurgitation (n = 4) and mild aortic regurgitation (n = 5). Arrhythmic events comprised supraventricular tachycardia (n = 2, both resolved), nodal rhythm (n = 1, transient), right bundle branch block (n = 5, persistent in four), and left bundle branch block (n = 1, resolved). Residual shunt was present in 36.4% immediately, declining to 9.8% at follow-up. Larger VSD diameter (OR 1.75, 95% CI 1.14-2.69) and higher body weight (OR 1.07, 95% CI 1.00-1.15) were independent predictors. No late complete AV block, endocarditis, or embolization occurred. Patients treated with Konar-MF were younger and lighter, while Nit-Occlud was associated with higher residual shunt rates (85.7% vs. 33.0%, p = 0.010).</p><p><strong>Conclusion: </strong>Transcatheter VSD closure in children demonstrated high success, acceptable complication rates, and favorable long-term outcomes. Results were influenced by device choice, defect size, and patient characteristics, highlighting the need for individualized strategies and continued surveillance.</p>","PeriodicalId":74993,"journal":{"name":"The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13226753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148140068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of left ventricular assist devices on kidney function: a systematic review and meta-analysis.","authors":"Alireza Hosseini, Bahar Darouei, Reza Amani-Beni, Davood Shafie, Sadegh Mazaheri-Tehrani, Mohammad Ali Haghighatpanah, Maryam Heidarpour, Ehsan Amini-Salehi, Seyyed Mohammad Hashemi, Anil Harrison, Irbaz Hameed, Christopher M Reid, Mohammad Reza Movahed","doi":"10.1186/s43044-026-00750-7","DOIUrl":"10.1186/s43044-026-00750-7","url":null,"abstract":"<p><strong>Background: </strong>Kidney dysfunction is common in patients with advanced heart failure and is associated with adverse clinical outcomes. Left ventricular assist device (LVAD) implantation may influence renal function through hemodynamic and cardiorenal changes. We performed a meta-analysis to evaluate longitudinal changes in estimated glomerular filtration rate (eGFR) following LVAD implantation.</p><p><strong>Results: </strong>We systematically searched six databases for studies reporting eGFR before and after LVAD implantation until March 2026. The primary analysis used a multivariate random-effects meta-analysis to jointly pool repeated follow-up estimates while accounting for within-study dependence across time points. Pooled mean changes in eGFR and 95% confidence intervals (CIs) were estimated at 1 week, 2 weeks, 1 month, 3 months, 6 months, 9 months, 1 year, 2 years, and 3 years after implantation. A total of 38 studies contributing 95 effect sizes were included. Compared with baseline, pooled mean eGFR was significantly higher at 1 week (18.83 mL/min/1.73 m²; 95% CI: 13.21, 24.46), 2 weeks (18.29; 95% CI: 12.11, 24.48), 1 month (23.77; 95% CI, 19.48, 28.07), 3 months (15.20; 95% CI: 10.95, 19.46), 6 months (7.97; 95% CI: 3.72, 12.22), 9 months (8.27; 95% CI: 2.10, 14.44), and 1 year (7.34; 95% CI: 2.83, 11.85), but not at 2 or 3 years. In subgroup analyses, studies with baseline eGFR < 60 mL/min/1.73 m² showed significant increases across all evaluated follow-up intervals, whereas those with baseline eGFR ≥ 60 mL/min/1.73 m² showed significant increases only through 3 months.</p><p><strong>Conclusions: </strong>LVAD implantation was associated with higher eGFR during the early postoperative period, with the largest increase observed at 1 month. However, because most included studies were pre-post analyses without non-LVAD comparator groups, these findings should be interpreted cautiously and do not establish a causal effect. Future research should explore the long-term impact of LVAD on renal health to optimize care strategies and outcomes.</p>","PeriodicalId":74993,"journal":{"name":"The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13212856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148038526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a cardiac rehabilitation program on anthropometric and functional parameters: an observational pre-post study.","authors":"Estrella García-Sánchez, Mirian Santamaría-Peláez, Jerónimo J González-Bernal, Josefa González-Santos, Jessica Fernández-Solana, Rodrigo Vélez-Santamaría","doi":"10.1186/s43044-026-00752-5","DOIUrl":"10.1186/s43044-026-00752-5","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiac rehabilitation is a multidisciplinary intervention designed to improve functional capacity and quality of life in patients with cardiovascular diseases. However, its impact on anthropometric and functional parameters remains an important area of study. This study evaluates the effects of a cardiac rehabilitation program on body mass index, abdominal circumference, blood pressure, heart rate, energy expenditure measured in METs, and NYHA functional classification.</p><p><strong>Methods: </strong>An observational pre-post study without a control group was conducted with 287 patients diagnosed with cardiovascular disease who completed a cardiac rehabilitation program. Anthropometric and functional variables were measured before and after the intervention. Statistical analysis included paired-sample t-tests and the Wilcoxon test for NYHA classification, with a significance level of p < 0.05.</p><p><strong>Results: </strong>Significant reductions were observed in BMI (pre: 27.79 ± 4.31 kg/m²; post: 27.11 ± 4.09 kg/m²; p < 0.001) and abdominal circumference (pre: 100.38 ± 11.16 cm; post: 97.33 ± 12.28 cm; p < 0.001). Systolic and diastolic blood pressure significantly decreased (p < 0.001). An increase in energy expenditure measured in METs was found (pre: 7.89 ± 2.68; post: 10.52 ± 2.63; p < 0.001), as well as in maximum heart rate. Additionally, NYHA functional classification improved (Z = -9.356, p < 0.001) with a reduction in the proportion of patients in classes III and II and an increase in class I.</p><p><strong>Conclusion: </strong>The cardiac rehabilitation program resulted in significant improvements in body composition, blood pressure, functional capacity, and NYHA classification. These findings support the importance of cardiac rehabilitation as an effective strategy in managing patients with cardiovascular diseases. Further strategies should be implemented to improve adherence and assess the long-term impact of the intervention.</p>","PeriodicalId":74993,"journal":{"name":"The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13197516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147990339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}