{"title":"A New Partnership to Advance Pressure Injury Science and Practice.","authors":"David M Brienza","doi":"10.1097/ASW.0000000000000411","DOIUrl":"https://doi.org/10.1097/ASW.0000000000000411","url":null,"abstract":"","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"39 2","pages":"62"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146257072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of Urinary Catheter-related Pressure Injury Development in Patients in the Intensive Care Unit.","authors":"Yeliz Çulha, Saliha Seran Akay, Ceren Çikendin, Funda Büyükyilmaz","doi":"10.1097/ASW.0000000000000391","DOIUrl":"10.1097/ASW.0000000000000391","url":null,"abstract":"<p><strong>Abstract: </strong></p><p><strong>Objective: </strong>This study was conducted to investigate the development of urinary catheter-related pressure injury (UCPI) in patients hospitalized in the intensive care unit (ICU).</p><p><strong>Methods: </strong>This descriptive study included 60 patients with urinary catheters who were hospitalized in the adult ICU of a training and research hospital in Istanbul between January and June 2024. Patient Information Form, Glasgow Coma Scale (GCS), Braden Risk Assessment Scale, Urinary Catheter-Related Pressure Injury Assessment Form, and Pressure Injury Staging and Follow-up Form were used to collect data.</p><p><strong>Results: </strong>The majority of patients (53.3%) were female, their mean age was 74.42±16.17 years, the mean length of stay in the ICU was 19.25±26.73 days, 90% were immobile, and the mean duration of urinary catheterization was 19.25±26.73 days. Urinary catheter-related pressure injury developed in 78.3% of the patients, PI developed on the outer side of the left thigh in 46.7%, and the mean duration of UCPI development was 2.47±1.86 days. Urinary catheter-related PI did not occur in 83.3% of the patients on the first day, 80% on the second day, and 60% on the third day; Stage 1 UCPI developed in 60% on the fourth day, and Stage 1 UCPI developed in 73.3% on the fifth day. In addition, body mass index, duration of mechanical ventilation, and the time of urinary catheter application were effective variables in the development of UCPI.</p><p><strong>Conclusions: </strong>The risk of UCPI increases as the duration of medical device use becomes longer, and urinary catheters are one of the most common devices associated with medical device-related PIs. Although the risk of PI associated with urinary catheters is high in the ICU, appropriate precautions, risk assessment, evidence-based practices, and early implementation of appropriate nursing interventions may allow the prevention of PI.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"E86-E92"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146049944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Longitudinal Braden Scale Score Trajectories and Their Association With Pressure Injury Development in Mechanically Ventilated Patients: A Retrospective Cohort Analysis.","authors":"Qiufeng Zhuang, Shiji Xiao, Xiuhua Zhou","doi":"10.1097/ASW.0000000000000404","DOIUrl":"10.1097/ASW.0000000000000404","url":null,"abstract":"<p><strong>Objective: </strong>To identify distinct trajectories of Braden Scale scores in critically ill ventilated patients and evaluate their association with pressure injury (PI) development using Latent Growth Mixture Modeling (LGMM), while assessing the prognostic value of these trajectories for early risk identification.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed data from 7339 adult patients (18 years and above) from the Medical Information Mart for Intensive Care database who received mechanical ventilation for at least 24 hours. Patients required at least 3 Braden score assessments during intensive care unit (ICU) stay. Braden scores were collected from ICU admission up to 48 hours. Latent Growth Mixture Modeling identified distinct trajectories, and competing risk models evaluated the association between trajectories and 14-day PI development, with death as a competing event.</p><p><strong>Results: </strong>Latent Growth Mixture Modeling identified 4 distinct trajectories: steadily improving group (n=1549, 21.1%), rapidly deteriorating group (n=912, 12.4%), stable-slight improvement group (n=3251, 44.3%), and persistently low group (n=1627, 22.2%). The persistently low group showed the highest mortality (42%) and PI incidence (37%). During the first 48 hours, compared with the steadily improving group, adjusted hazard ratios were significantly higher: rapidly deteriorating group (1.49, 95% CI: 1.05-2.12), stable-slight improvement group (2.40, 95% CI: 1.83-3.17), and persistently low group (4.07, 95% CI: 3.04-5.45). Risk remained elevated during 48 to 120 hours but attenuated by 120 to 336 hours.</p><p><strong>Conclusions: </strong>Early trajectory patterns of Braden scores demonstrate distinct associations with PI risk. The identification of these patterns, particularly during the first 48 hours, may enable earlier risk stratification and more targeted preventive strategies. Dynamic monitoring of Braden scores could enhance PI risk assessment and prevention in ICU settings.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"E77-E85"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146049954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Bi, Jianmei Shao, Wen Yao, Songmei Yang, Nana Liu, Aihua Liu
{"title":"Risk Factors and Predictive Model for Occupational Contact Dermatitis Among Nurses in Hefei, China: A Cross-sectional Study.","authors":"Juan Bi, Jianmei Shao, Wen Yao, Songmei Yang, Nana Liu, Aihua Liu","doi":"10.1097/ASW.0000000000000383","DOIUrl":"10.1097/ASW.0000000000000383","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the prevalence, risk factors, and protective measures of occupational contact dermatitis (OCD) among nurses in Hefei, China; create a predictive model for nurses' experiencing contact dermatitis; and assess the model's effectiveness.</p><p><strong>Methods: </strong>A cross-sectional survey using the Nordic Occupational Skin Questionnaire 2002 was conducted among 273 nurses at a hospital in Hefei, China, from December 2022 to February 2023. Predictive factors for nurses' contact dermatitis were identified through regression analyses. A predictive model, represented by a nomogram, was established based on these factors, and its predictive performance was evaluated by calibration curve and the decision curve analysis plot.</p><p><strong>Results: </strong>Contact dermatitis was found among 20.51% of nurses. Those with allergies were 4.34 times more likely to develop OCD (95% CI = 2.29-8.24), whereas individuals with dry skin had a 2.82 times higher risk (95% CI = 1.07-7.47). Using protective gloves and uniforms reduced the risk by 50% to 60%. The established nomogram model exhibited an area under the receiver operating characteristic curve of 0.734 (95% CI = 0.661-0.807), demonstrated satisfactory calibration, and showed a favorable net benefit.</p><p><strong>Conclusions: </strong>Nurses with allergies or dry skin are more likely to develop OCD, but wearing gloves is a helpful preventive measure. The created model predicts nurses' OCD risk, which can identify high-risk individuals for early intervention.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"E16-E22"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145848650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feasibility and Safety of Utilizing Air Ultrafine Bubble Water for Preoperative Skin Cleaning Before Foot and Ankle Surgery.","authors":"Yuki Tabuse, Makoto Hirao, Takaaki Noguchi, Gensuke Okamura, Shigeyoshi Tsuji, Yuki Etani, Kosuke Ebina, Hyota Takamatsu, Shiro Ohshima, Seiji Okada, Jun Hashimoto","doi":"10.1097/ASW.0000000000000367","DOIUrl":"10.1097/ASW.0000000000000367","url":null,"abstract":"<p><strong>Objective: </strong>The surgical site infection (SSI) rate is reportedly higher with foot and ankle surgeries than with other parts. This is problematic for rheumatoid arthritis and diabetes mellitus patients. Ultrafine bubble (UFB) technology is expected to elongate the duration for which the surgical site can remain disinfected, thanks to its stable nanobubble structure and disinfection effects by its own radical actions. This study evaluated the feasibility and safety of preoperative skin cleaning utilizing UFB water before foot/ankle surgery.</p><p><strong>Methods: </strong>This observational study retrospectively examined 219 extremities in 217 patients who had undergone foot/ankle surgery. Preoperative skin cleaning was performed using either conventional alcohol (concentration 80%) (conventional group; 113 extremities) or 500 mL of UFB water and conventional alcohol (UFB group; 106 extremities). Frequencies of postoperative events such as blister formation, eschar formation (width >10 mm) on the wound, and wound dehiscence after suture removal were compared, as was the time until suture removal.</p><p><strong>Results: </strong>Rates of eschar formation and wound dehiscence after suture removal were significantly reduced in the UFB group. Time to suture removal was significantly shorter in the UFB group (12.9 d) than in the conventional group (15.5 d). All 3 cases with infected open wounds in the UFB water group achieved complete cure with wound closure within 2 weeks.</p><p><strong>Conclusions: </strong>Preoperative skin cleaning using air UFB water appears safe and might help prevent eschar formation and wound dehiscence after foot/ankle surgeries. These effects could improve wound healing for patients undergoing foot and ankle surgery.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"E29-E34"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145123958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Polak, Bogna Szołtys-Brzezowska, Laura Piejko
{"title":"Effect of Electrical Stimulation on Cytokines and Growth Factors Active in the Process of Wound Healing: A Systematic Review of In Vivo Animal Studies and Randomized Clinical Trials.","authors":"Anna Polak, Bogna Szołtys-Brzezowska, Laura Piejko","doi":"10.1097/ASW.0000000000000388","DOIUrl":"10.1097/ASW.0000000000000388","url":null,"abstract":"<p><strong>Objective: </strong>To systematically review in vivo animal studies and randomized clinical trials (RCTs) analyzing the effects of electrical currents on cytokine and growth factor levels involved in wound healing.</p><p><strong>Data sources: </strong>PubMed, EBSCO, Ovid, Elsevier, and online gray literature databases were searched for relevant studies.</p><p><strong>Study selection: </strong>Eligible studies were full-text, English-language in vivo reports or RCTs comparing at least 10 electrically stimulated (ES) wounds with 10 control wounds left untreated or treated with sham ES or nonphysical interventions.</p><p><strong>Data extraction: </strong>Extracted data included ES-induced changes in cytokine and growth factor levels in wounds or blood. Methodologic quality was assessed using the SYRCLE risk-of-bias tool (animal studies) and the PEDro scale (RCTs).</p><p><strong>Data synthesis: </strong>Eight studies (6 in vivo with 349 animals and 2 RCTs with 44 patients with diabetic foot ulcers) published between 2011 and 2021 were analyzed. ES protocols included direct current, low-voltage and high-voltage monophasic, biphasic, and alternating currents applied at sub-sensory to motor intensities. Most in vivo studies reported reduced cytokine levels (IL-1β, IL-6, TNF-α, and IL-10) and increased growth factors (VEGF, FGF-2, EGF, and TGF-β1). RCTs found ES increased VEGF in wounds and blood but did not affect soluble VEGF receptor-2 levels.</p><p><strong>Conclusions: </strong>Electrical stimulation favorably modulates cytokine and growth factor expression, supporting faster wound healing. However, due to the limited number and heterogeneity of studies, further high-quality research is required to establish optimal ES parameters.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"E43-E56"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145848672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of the TIME-CDST-based Approach in the Management of Incontinence-associated Dermatitis in Patients With Severe Trauma and Obesity.","authors":"Manli Tang, Jie Tan, Qin Xu, Jiangfeng Guo","doi":"10.1097/ASW.0000000000000382","DOIUrl":"10.1097/ASW.0000000000000382","url":null,"abstract":"<p><strong>Abstract: </strong></p><p><strong>Objective: </strong>To investigate the effectiveness of the TIME-CDST (Tissue, Inflammation or Infection, Moisture, and Epidermal/Edge status-Clinical Decision Support Tool) in the prevention and management of incontinence-associated dermatitis (IAD) in patients with severe trauma and obesity.</p><p><strong>Methods: </strong>A total of 50 patients were assigned to the control group from February to April 2023, and 76 patients were designated as the intervention group from May to July 2023. In the control group, routine skin care measures were taken. The intervention group applied TIME-CDST for systematic hierarchical management, which included assessment, collaboration, control, decision-making, and evaluation. The incidence of IAD and fungal dermatitis, the severity of IAD, and healing time were compared between the 2 groups.</p><p><strong>Results: </strong>The application of TIME-CDST led to a decrease in the incidence of IAD from 44.00% to 26.32% (χ 2 =4.244, P <.05) and a reduction in fungal dermatitis from 27.27% to 0.05% (χ 2 =4.683, P <.05). The intervention also reduced the severity of IAD ( Z =-2.331, P <.05) and shortened the healing time ( Z =-2.321, P <.05).</p><p><strong>Conclusions: </strong>The use of TIME-CDST in patients with severe trauma and obesity could reduce the incidence and severity of IAD and promote early healing of dermatitis.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"32-37"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145916622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siddhartha Sood, Ryan Geng, Asfandyar Mufti, Safa Usman, R Gary Sibbald
{"title":"Basic Low-cost Removable Footwear for Diabetic Foot Ulcer Offloading: A Systematic Review.","authors":"Siddhartha Sood, Ryan Geng, Asfandyar Mufti, Safa Usman, R Gary Sibbald","doi":"10.1097/ASW.0000000000000385","DOIUrl":"10.1097/ASW.0000000000000385","url":null,"abstract":"<p><p>Offloading is an established foot care practice for diabetic foot ulcers (DFUs) involving the use of footwear, casts, and other devices to reduce plantar pressure, promote healing, and prevent ulcer formation. Currently, the criterion standard for offloading diabetic foot involves the irremovable total contact cast (TCC); however, application is resource-intensive, and patient adherence can be challenging because of functional limitations. The objective of this study was to determine the efficacy of removable offloading footwear for DFU healing and prevention. MEDLINE and Embase databases were searched on July 25, 2023, with keywords relating to \"diabetic foot\" and \"offloading devices.\" Two researchers screened articles initially by title and abstract, followed by full-text screening. Articles were included if they reported on patients with DFU who were treated with removable offloading devices. Data extraction was completed by 2 researchers independently. Data extracted included patient demographics, healing time, amputation rate, recurrence rate, and offloading devices used. Outcomes, including healing time, healing rate, amputation rate, and recurrence rate, were pooled. Studies were assessed for quality using the Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence. Twenty-three studies were included, reflecting 1694 patients. In 618 cases with an active ulcer, a mean healing rate of 71% was observed. The mean time required for healing was 68.4 days. Mean amputation rate was 15.4%. In 760 cases evaluating prevention of recurrence, the mean recurrence rate documented was 22.5% with a follow-up duration of 39.7 months. Three hundred sixteen cases evaluated the prevention of new DFUs, noting an ulcer incidence rate of 2%. Simple and removable offloading devices may be an accessible and low-cost option for the prevention of new or recurrent ulcers. Healing and amputation outcomes were not superior to published literature regarding TCC. Nonetheless, they may provide moderate utility in patients unable to tolerate TCC or in low-resource settings.</p><p><strong>General purpose: </strong>To present the results of a systematic review evaluating the utility of accessible and removable offloading footwear for diabetic foot ulcer (DFU) prevention, healing, and recurrence.</p><p><strong>Target audience: </strong>This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin, wound, and diabetic foot care.</p><p><strong>Learning objectives/outcomes: </strong>After completing this continuing education activity, the participant will: Summarize the evidence the authors considered when evaluating the use of offloading footwear for DFUs.Identify the characteristics of the patients and clinical environments in which offloading devices were used.Illicit the results of the authors' study detailing the utility of basic offloading footwear for prevention, healing, and r","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"11-16"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145987780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}