Paul T Gomez, Karen L Andrews, Jennifer R Arthurs, Alison J Bruce, Saranya P Wyles
{"title":"Platelet-Rich Plasma in the Treatment of Diabetic Foot Ulcers.","authors":"Paul T Gomez, Karen L Andrews, Jennifer R Arthurs, Alison J Bruce, Saranya P Wyles","doi":"10.1097/ASW.0000000000000229","DOIUrl":"10.1097/ASW.0000000000000229","url":null,"abstract":"<p><strong>Background: </strong>Chronic nonhealing neuropathic foot ulcers affect approximately 15% to 30% of patients with diabetes mellitus and are associated with significant morbidity and mortality. Although current strategies to address these chronic wounds include a multifactorial approach, clinical outcomes remain poor and warrant improvement. Platelet-rich plasma (PRP), derived from autologous or allogeneic blood, is an emerging regenerative product that aims to serve as an adjuvant to standard diabetic foot ulcer (DFU) treatment.</p><p><strong>Objective: </strong>To examine controlled clinical trials investigating the efficacy of platelet-rich therapies in promoting healing of chronic DFUs.</p><p><strong>Data sources: </strong>The PubMed/MEDLINE database.</p><p><strong>Study selection: </strong>Researchers selected 11 controlled clinical trials published between 2011 and 2021 that investigated the efficacy of PRP treatments for chronic DFUs.</p><p><strong>Data extraction: </strong>Extracted data included study type and size, participant sex and age, duration of diabetes, glycated hemoglobin levels, baseline ulcer area, wound duration, healing parameters, PRP preparation approach, and application type.</p><p><strong>Data synthesis: </strong>Randomized prospective studies (n = 8), prospective controlled studies (n = 2), and a double-blind, randomized controlled study (n = 1) were included in the review. In general, PRP plus standard of care provided superior wound healing, in both percentage of wound closure and healing rate, compared with standard of care alone.</p><p><strong>Conclusions: </strong>Use of PRP as an adjuvant for healing chronic DFUs appears to improve wound healing. Further research on optimizing PRP preparation and exploring combinatorial approaches will be important in advancing this avenue for chronic wound healing.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"37 11&12","pages":"608-615"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142961965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bagging an Extremity for Negative-Pressure Wound Therapy: A Case Report.","authors":"Krešimir Bulić, Lucija Gatin","doi":"10.1097/ASW.0000000000000224","DOIUrl":"10.1097/ASW.0000000000000224","url":null,"abstract":"<p><strong>Abstract: </strong>Negative-pressure wound therapy (NPWT) is used to promote wound closure or to prepare a wound for definite coverage. However, the anatomy of the hand makes it difficult to apply dressings that require an airtight seal. In this report, the authors describe the case of a patient with an extensive defect of his right hand and forearm who was treated with a free fibula osteocutaneous flap transfer. The remaining defect was covered with a split-thickness skin graft following NPWT. An airtight seal was achieved by placing the whole extremity in a sterile bag and sealing it proximal to the defect. The authors present a simple and innovative way of treating defects on upper extremities with NPWT with excellent results.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"37 11&12","pages":"1-3"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sawyer Cimaroli, Danilo Lozada, James Daniels, Brian Gillette, Scott Gorenstein
{"title":"Treatment of 50 Acute and Chronic Wounds of Multiple Etiologies: A Case Series Looking at Outcomes and Utility of an Extended-Wear Transforming Powder Dressing.","authors":"Sawyer Cimaroli, Danilo Lozada, James Daniels, Brian Gillette, Scott Gorenstein","doi":"10.1097/ASW.0000000000000221","DOIUrl":"10.1097/ASW.0000000000000221","url":null,"abstract":"<p><strong>Abstract: </strong>Increasing healthcare costs, limited healthcare resources, an aging population, and lifestyle-related diseases make wound management a growing clinical, social, and economic burden. This case series investigated the use of a novel, biocompatible, polymer-based transforming powder dressing (TPD) that transforms in situ to a shape-retentive wound matrix upon hydration for treating wounds of various etiologies.In this institutional review board-approved single-center retrospective case series, the researchers evaluated various acute and chronic wounds treated with TPD over a period of 2 years. Wounds were followed from the first TPD application up to 1 month after the last TPD application or until the wound healed or the patient was lost to follow-up, whichever came first. The researchers evaluated wound etiology, location, number of applications, change in wound surface area, and comorbidities.The researchers identified 50 patients who were treated with TPD and had at least one follow-up visit during the retrospective study period. The majority of wounds treated with TPD were venous leg ulcers (n = 27) followed by traumatic wounds (n = 11) and skin tears (n = 7). Normal rates of wound healing (>10% per week) were observed in the majority of patients (36/50, 72%) over their duration of treatment. Complete healing during the study period was observed in 43% of venous leg ulcers, 55% of traumatic wounds, 71% of skin tears, and 80% of other wound types. No adverse effects of TPD administration were observed. Treatment with TPD resulted in significant reductions in wound area of nearly all wounds, regardless of etiology.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"37 11&12","pages":"1-5"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142961974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Symptoms on Quality of Life in Patients with Chronic Wounds.","authors":"Chen Lin, Hu Ailing, Li Caifei, Liu Yuan","doi":"10.1097/ASW.0000000000000219","DOIUrl":"10.1097/ASW.0000000000000219","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the occurrence of symptoms and quality of life (QoL) among patients with chronic wounds and the impact of chronic wounds on QoL.</p><p><strong>Methods: </strong>Researchers evaluated 200 patients with chronic wounds using a general information questionnaire, a modified version of the Memorial Symptom Assessment Scale, and the Chinese version of the Cardiff Wound Impact Questionnaire. They performed correlation and linear regression analyses to explore the impact of symptoms on QoL.</p><p><strong>Results: </strong>Mean symptoms scores were all moderately severe and ranged as follows: 0 to 7.06 ± 3.85 for mean total symptom, 0 to 2.69 ± 1.33 for mean frequency, 0 to 2.27 ± 1.02 for mean severity, and 0 to 2.29 ± 1.29 for mean distress. Scores on the three dimensions of QoL (daily life, social life, and well-being) were 51.61 ± 14.73, 48.63 ± 17.20, and 47.45 ± 8.65, respectively. Patients' symptoms on each subscale were negatively correlated with the dimensions of QoL (r = -0.383 to -0.559, P < .01). Multiple linear regression analyses showed that 9 symptoms collectively explained 66.1% of the total variance of daily life (P < .01); 7 symptoms explained 59.0% of the total variance of social life (P < .01); and 10 symptoms explained 59.6% of the total variance of well-being (P < .01).</p><p><strong>Conclusions: </strong>Patients with chronic wounds had high levels of psychological symptoms and moderate QoL, scoring lowest on well-being. Sleep disruption, limitations in activity, and scarring were the main symptoms affecting their QoL. Nurses should prioritize managing these symptoms to improve patients' QoL.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"37 11&12","pages":"1-9"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence, Risk Factors, Causes, Assessments, and Prevention of Medical Adhesive-Related Skin Injury: A Scoping Review.","authors":"Meichen Du, Mei Liu","doi":"10.1097/ASW.0000000000000235","DOIUrl":"10.1097/ASW.0000000000000235","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate research on medical adhesive-related skin injury (MARSI), focusing on its incidence, prevalence, risk factors, causes, assessments, and prevention.</p><p><strong>Data sources: </strong>Searches were conducted on Wanfang Data, China National Knowledge Infrastructure, PubMed, Web of Science Core Collection, MEDLINE, EMBASE, and the Cumulative Index of Nursing and Allied Health Literature Plus with Full Text.</p><p><strong>Study selection: </strong>Using search terms \"medical adhesive related skin injury\", \"MARSI\", \"adhesive skin injury\", and \"medical tape-induced skin injury\", the authors selected 43 original articles published between January 1, 2001, and May 12, 2022, in English or Chinese.</p><p><strong>Data extraction: </strong>Extracted details included the first author; publication year; study location; study type; and specifics on MARSI, such as causes, affected body areas, assessment methods, incidence, prevalence, and prevention.</p><p><strong>Data synthesis: </strong>Medical adhesive-related skin injury frequently occurred on the face and at venipuncture sites. Acrylate-containing adhesives were more likely to cause MARSI. Risk factors include extended hospital stays, lower Braden Scale scores, mechanical ventilation, edema, poor skin condition, and use of certain medications. Incidence or prevalence exceeded 10% across populations, peaking at 60.3% in the pediatric surgical ICU. Mechanical injury had the highest incidence and prevalence among MARSI types. Studied interventions and quality improvement measures were effective in reducing MARSI.</p><p><strong>Conclusions: </strong>Despite increasing interest, evidence for reducing MARSI is limited. Future research should focus on distinguishing MARSI types, clarifying incidence and prevalence, assessing risk factors, and implementing screening and quality improvement initiatives.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"37 11&12","pages":"1-10"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142961967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dan Berlowitz, Bianca Konchinski, Lingming Chen, Sheila Sablon DeCastro
{"title":"The 2023 Update on Pressure Injuries: A Review of the Literature.","authors":"Dan Berlowitz, Bianca Konchinski, Lingming Chen, Sheila Sablon DeCastro","doi":"10.1097/ASW.0000000000000218","DOIUrl":"10.1097/ASW.0000000000000218","url":null,"abstract":"<p><strong>General purpose: </strong>To provide a summary of six articles published in 2023 that provide important new data or insights about pressure injuries (PIs).</p><p><strong>Target audience: </strong>This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and registered nurses with an interest in skin and wound care.</p><p><strong>Learning objectives/outcomes: </strong>After participating in this educational activity, the participant will:1. Summarize selected current evidence addressing the prevention of PIs.2. Evaluate new studies exploring PI treatment modalities.3. Identify recent findings concerning the role of artificial intelligence in staging PIs.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"37 11&12","pages":"571-578"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142961969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the Exciting Possibilities of Visual ChatGPT in Pressure Injury Care: Time for Change?","authors":"Polat Goktas, Aycan Kucukkaya, Pelin Karaçay","doi":"10.1097/ASW.0000000000000239","DOIUrl":"10.1097/ASW.0000000000000239","url":null,"abstract":"","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"37 11&12","pages":"1-4"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patients' Willingness to Perform Self-Wound Care: A Cross-sectional Study in the Primary Healthcare Sector in Singapore.","authors":"Ling Jia Goh, Xiaoli Zhu","doi":"10.1097/ASW.0000000000000234","DOIUrl":"10.1097/ASW.0000000000000234","url":null,"abstract":"<p><strong>Background: </strong>Patient adherence to performing self-wound care (SWC) has a direct influence on the success of telewound care, a healthcare delivery mode that emerged in 2016 in National Healthcare Group Polyclinics in Singapore to relieve the healthcare burden. This mode of delivery was useful during the pandemic, when nonurgent face-to-face visits were switched to the use of telecommunications for consultation. Telewound care requires that patients be willing to perform wound care on their own; however, whether patients are willing to do so remains unknown.</p><p><strong>Objective: </strong>To identify factors influencing patients' willingness to undertake SWC using a locally validated tool, the Self-Wound Care Acceptance Survey (SWCAS).</p><p><strong>Methods: </strong>The authors recruited 328 participants with wounds from six polyclinics using convenience sampling. Participants rated the 17 items on the SWCAS using a 5-point Likert-type scale, from 1 (strongly disagree) to 5 (strongly agree). Higher scores indicate greater willingness to perform wound self-care.</p><p><strong>Results: </strong>Only 34.2% of the participants were willing to perform SWC. Patients who had a wound on their back and had transport provided and medical bills paid by family scored lower on the SWCAS. In contrast, patients who had higher education levels, were in the younger age group, were employed, were students, and had medical bills partially or fully paid by their company or insurance scored higher on the SWCAS. Post hoc tests indicated that patients with a wound on the back scored significantly lower on the SWCAS than did patients with wounds in other locations (Ps < .05).</p><p><strong>Conclusions: </strong>Additional patient education is needed to increase patients' acceptance of the SWC concept. Actively promoting SWC by distributing patient education information sheets and pamphlets to eligible patients, addressing negative thoughts or concerns, and encouraging positive thinking and autonomy may encourage patients to accept this concept.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"37 11&12","pages":"1-8"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142961963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rabia Oztas Kara, Bahar Sevimli Dikicier, Bilge Elcin
{"title":"A Case of Ramipril-Induced Angioedema and Solar Purpura.","authors":"Rabia Oztas Kara, Bahar Sevimli Dikicier, Bilge Elcin","doi":"10.1097/ASW.0000000000000236","DOIUrl":"10.1097/ASW.0000000000000236","url":null,"abstract":"<p><strong>Abstract: </strong>This case report describes a patient who developed solar purpura after treatment for angioedema associated with ramipril, an angiotensin-converting enzyme inhibitor. The patient presented to the ED with angioedema. She had been using ramipril for 2 years. Two days after she was admitted, a malar \"butterfly\" rash occurred on her face and purpura on her lower lip and chin, as well as the extensor part of her forearm. After testing and review of the patient history, she was diagnosed with solar purpura and began topical corticosteroid and antiscar cream treatment. The patient's lesions healed with an atrophic scar in 3 weeks. To the authors' knowledge, this is the first such case to be reported in the literature.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"37 11&12","pages":"1-3"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Öznur Tiryaki, Hamide Zengin, Nursan Çınar, Meltem Karabay, İbrahim Caner, Ertuğrul Güçlü
{"title":"Comparison of Coconut and Sunflower Seed Oils in Improving the Skin Integrity and Weight Gain of Infants in the Neonatal ICU.","authors":"Öznur Tiryaki, Hamide Zengin, Nursan Çınar, Meltem Karabay, İbrahim Caner, Ertuğrul Güçlü","doi":"10.1097/ASW.0000000000000241","DOIUrl":"10.1097/ASW.0000000000000241","url":null,"abstract":"<p><strong>Objective: </strong>To determine the effects of sunflower seed oil and coconut oil on the skin integrity and weight gain of preterm infants in the neonatal ICU.</p><p><strong>Methods: </strong>In this randomized controlled trial, 66 preterm neonates (34-37 weeks' gestation) in the neonatal ICU of a training and research hospital were equally divided into three groups: sunflower seed oil, coconut oil, and control. The weights of neonates in all three groups were measured at admission to the neonatal ICU, at discharge, and at 1 month postdischarge. Their skin conditions were evaluated using the Neonatal Skin Condition Score and the Revised Northampton Neonatal Skin Assessment Tool at the same three time points.</p><p><strong>Results: </strong>At 1 month postdischarge, neonates in the sunflower seed oil and coconut oil groups weighed significantly more than those in the control group (P = .004). Mean Neonatal Skin Condition Score scores were significantly higher in the control group at 1 month postdischarge than in the sunflower seed oil and coconut oil groups (P = .000).</p><p><strong>Conclusions: </strong>Skin care with coconut oil and sunflower seed oil was effective in maintaining the skin integrity and weight of neonates at 1 month postdischarge. The authors recommend that randomized controlled trials on skin care in preterm infants using sunflower, coconut, and other oils be conducted with larger sample sizes.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"37 11&12","pages":"1-8"},"PeriodicalIF":1.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}