Advances in Skin & Wound Care最新文献

{"title":"Diabetic Foot Infections: A Toolkit for Wound Care Clinicians.","authors":"","doi":"10.1097/ASW.0000000000000427","DOIUrl":"https://doi.org/10.1097/ASW.0000000000000427","url":null,"abstract":"","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"39 3","pages":"E166"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phosphodiesterase 4 Inhibitor Use in Pediatric Patients With Atopic Dermatitis: A Meta-Analysis of Randomized Controlled Trials.","authors":"Gui-Lin Ran, Li-Chin Lu, Hui-Bin Wang, Jun-He Yang, Chia-Pang Chan, Hua-Mei Zhuang, Shao-Huan Lan","doi":"10.1097/ASW.0000000000000423","DOIUrl":"https://doi.org/10.1097/ASW.0000000000000423","url":null,"abstract":"<p><strong>Objective: </strong>To compare the clinical efficacy and safety of different topical phosphodiesterase 4 (PDE4) inhibitors for atopic dermatitis (AD) treatment in pediatric patients.</p><p><strong>Data sources: </strong>Clinical trials were identified from PubMed, Cochrane Library, EBSCO, Web of Science, and Ovid Medline databases until September 2023.</p><p><strong>Study selection: </strong>Only randomized controlled trials (RCTs) with topical PDE4 inhibitors versus topical vehicle treatment for pediatric patients with mild-to-moderate AD were included. This meta-analysis was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA) and was registered in PROSPERO. Data were pooled using the random-effects model if I2 >50%.</p><p><strong>Data extraction: </strong>Five RCTs were identified, which included 1877 pediatric patients with mild to moderate AD.</p><p><strong>Data synthesis: </strong>Overall, compared with the topical vehicle control, PDE4 inhibitors were associated with higher response rate in Investigator Global Assessment scores (OR: 3.56, 95% CI: 2.09 to 6.04, P = .005) and increased treatment success rates at weeks 2 (OR: 4.09, 95% CI: 2.32 to 7.21, P < .00001) and weeks 4 (OR: 3.06, 95% CI: 1.52 to 6.18, P = .002). PDE4 inhibitors also associated with higher Eczema Area and Severity Index scores (OR: -4.11, 95% CI: -4.83 to 3.39, P < .00001). There were no significant differences in adverse events (OR: 1.16; 95% CI: 0.93 to 1.44, P = .18) or drug-related adverse events (OR: 1.46, 95% CI: 0.99 to 2.15, P = .05).</p><p><strong>Conclusions: </strong>PDE4 inhibitors might be an effective and safe treatment option for pediatric patients with AD.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"39 3","pages":"E142-E149"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Sacral Marjolin Ulcer in a Patient With Prior Back Abscesses.","authors":"Joseph J Santora, Jae-Chiang Wong, Tyler Faimon","doi":"10.1097/ASW.0000000000000415","DOIUrl":"10.1097/ASW.0000000000000415","url":null,"abstract":"<p><p>A Marjolin ulcer is a cutaneous malignant growth typically associated with areas of prior injury and irritation, most commonly burn wounds. This case report documents a rare example of a sacral Marjolin ulcer that presented in a patient with a history of lower-back abscesses. There are numerous accounts of this malignancy arising in chronic wounds over many years, but reports of subacute presentations are scarcer. This report underlines the importance of early suspicion and diagnosis in patients who may not have the classic features.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"E157-E159"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146155677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skin Cancer and Wound Healing.","authors":"R Gary Sibbald, Elizabeth A Ayello","doi":"10.1097/ASW.0000000000000426","DOIUrl":"https://doi.org/10.1097/ASW.0000000000000426","url":null,"abstract":"","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"39 3","pages":"117"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myth: Wound/Ulcer Management Professionals Cannot Receive Medicare Payment if They Do Not Perform Procedures.","authors":"Kathleen D Schaum","doi":"10.1097/ASW.0000000000000428","DOIUrl":"https://doi.org/10.1097/ASW.0000000000000428","url":null,"abstract":"","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"39 3","pages":"119-120"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Call to Action: Enhancing Patient-Initiated Communication in Diabetic Below-Knee Amputation Cases for Improved Wound Center Outcomes.","authors":"Isabel Snee, Rachel N Rohrich, Victoria H Kim, Margaret E Greer, Karen R Li, Christian X Lava, Richard Youn, Christopher E Attinger","doi":"10.1097/ASW.0000000000000418","DOIUrl":"10.1097/ASW.0000000000000418","url":null,"abstract":"<p><strong>Objective: </strong>Patients undergoing below-knee amputation (BKA) for diabetic complications experience heightened anxiety and poor psychosocial outcomes. Though patient-initiated communication (PIC) clarifies uncertainty, it also increases clinical burden. Primary outcomes were PIC incidence within the perioperative period, PIC rationale, and PIC patient characteristics.</p><p><strong>Methods: </strong>From December 2021 to August 2023, a retrospective review of BKA patients analyzed PIC via phone calls and portal messages ±90 days of surgery. PIC patients were compared with non-PIC patients, with subgroup analysis of preoperative (pre-PIC) and postoperative (post-PIC) communication.</p><p><strong>Results: </strong>Of 151 BKA patients, 110 (72.8%) initiated 368 PIC encounters. Patients were predominantly male (68.2%), with a mean age of 57.8±13.8 years and a Charlson Comorbidity Index of 4.9±2.9. Pre-PIC (52.2%) was slightly more common than post-PIC (47.8%). PICs addressed administrative issues (37.2%), wound care (17.6%), and medications (19.3%). PIC patients were more likely to be discharged to rehabilitation or home ( P =.046), had shorter length of stay (LOS) [16 (10) vs. 18.5 (15) days, P =.0086], and returned to the operating room (ROR) within 30 days for complications ( P =.037). Multivariate analysis found discharge to home (OR: 6.00, P =.025) and ROR (OR: 0.256, P =.012) independently predicted PIC. Pre-PIC patients were more often married ( P =.038) and discharged home ( P =.045). Post-PIC patients had longer LOS ( P =.005) and fewer RORs ( P =.006).</p><p><strong>Conclusions: </strong>Identifying high-risk groups and PIC rationale will improve the authors' institution's ability to address patient concerns.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"145-151"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146155713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nurses' Knowledge and Practices Related to Wound and Peri-Wound Cleansing in Canada.","authors":"Kimberly LeBlanc, Samantha Wiesenfeld, Kevin Woo","doi":"10.1097/ASW.0000000000000407","DOIUrl":"10.1097/ASW.0000000000000407","url":null,"abstract":"<p><strong>Objective: </strong>Inadequate wound management can lead to increased complications, costs, and risks, highlighting the importance of health care professionals' knowledge in wound and peri-wound care. Although previous studies have identified knowledge gaps among nurses, national data on Canadian nurses' understanding of wound cleansing remain limited. This study aimed to evaluate Canadian nurses' knowledge and practices regarding wound and peri-wound cleansing and assess their alignment with evidence-informed recommendations.</p><p><strong>Methods: </strong>A descriptive, cross-sectional, self-administered online survey was conducted from June to August 2024 to gather data on current practices. Research ethics board exemption was obtained from the Joint West Park Healthcare Centre-Toronto Central LHIN-Toronto Grace Health Centre Research Ethics Board (JREB).</p><p><strong>Results: </strong>Survey results revealed that 91% (n=180) of nurses recognize the role of regular wound cleansing in promoting healing, whereas 90% (n=178) believe it helps reduce biofilm and prevent infection. In addition, 99% (n=196) support routine peri-wound cleansing, and 94% (n=186) emphasize the use of nondamaging cleansers. Despite this knowledge, gaps persist between belief and practice. For example, 68% (n=135) support gauze soaking, yet only 30% (n=59) use this method routinely. Only 54% (n=107) correctly identified the need for antiseptics on peri-wound areas, and just 34% (n=67) consider hypochlorous acid and sodium hypochlorite equally safe.</p><p><strong>Conclusions: </strong>The findings underscore the need for enhanced education to bridge the gap between knowledge and practice. Aligning wound care practices with current evidence is essential to improving outcomes, preventing infection, and ensuring patient safety across Canadian health care settings.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"135-140"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147430068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetic Foot Infections: A Toolkit for Wound Care Clinicians.","authors":"Kyle Kilby, Christopher Lata, Lucas Castellani, Dale Kalina Samji, R Gary Sibbald, John H Gregory, Ranjani Somayaji","doi":"10.1097/ASW.0000000000000422","DOIUrl":"https://doi.org/10.1097/ASW.0000000000000422","url":null,"abstract":"<p><p>Diabetic foot infections (DFIs) are a serious complication of diabetes, leading to high rates of hospital admission, amputation, and early death-particularly in persons living in resource-limited communities. Although the updated International Working Group on the Diabetic Foot guidelines in 2024 provide well-laid-out strategies for managing DFIs, these tend to be better suited for use in well-resourced centers. This case-based review discusses and applies these guidelines for an approach to DFI in real-world scenarios. It focuses on supporting health care providers working in community and resource-limited settings. The review explores how to recognize and diagnose DFI, including the use of imaging modalities, and how to distinguish soft tissue infection from bone infection or noninfectious entities. Management strategies are detailed regarding antibiotic considerations and approaches, including in resource-limited settings, and when other interventions or surgical referral may be important. Practical clinical cases are used to illustrate key points, emphasizing how care may be adapted based on the context. The authors also consider health equity aspects by identifying barriers that may be faced by patients who are from racialized backgrounds and live in resource-limited settings. The review aims to equip frontline wound clinicians with a pragmatic approach to managing DFIs that is grounded in up-to-date evidence framed in a real-world context.JOURNAL/aswca/04.03/00129334-202604000-00004/figure1/v/2026-03-10T151712Z/r/image-jpeg GENERAL PURPOSE: To provide clinicians with an evidence-based approach to the diagnosis and management of diabetic foot infections (DFIs). TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and registered nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After participating in this educational activity, the participant will:Analyze evidence-based clinical and laboratory findings to accurately diagnose (DFIs) and diabetic foot osteomyelitis.Evaluate patient-specific clinical data to select evidence-based management strategies for patients with (DFIs) and diabetic foot osteomyelitis.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"39 3","pages":"124-134"},"PeriodicalIF":1.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Pressure Injuries: A Descriptive Study of Patient Characteristics.","authors":"Chungmei Shih, C William Pike, Gavin Hui, Cassendra A Munro","doi":"10.1097/ASW.0000000000000390","DOIUrl":"10.1097/ASW.0000000000000390","url":null,"abstract":"<p><strong>Abstract: </strong></p><p><strong>Objective: </strong>The perioperative setting presents unique challenges that contribute to the development of pressure injury (PI). In this study, the authors explore the incidence and baseline characteristics of perioperative patients (adult, inpatient, and surgical patient population with at least 3 days' hospital stay) who undergo surgery and have PI outcomes.</p><p><strong>Methods: </strong>This descriptive retrospective study was conducted using electronic medical record data of 55,270 patients from an academic health care system. Differences in baseline characteristics between patients with versus without PI were examined using the Fisher exact test, χ 2 tests, and t tests.</p><p><strong>Results: </strong>The incidence of perioperative pressure injury (PPI) was 0.5%. Of the PPI group, 65.7% developed PPI after cardiovascular surgery. The most prevalent PPI stage was unstageable, followed by Stage 2 and deep tissue injury. The most common locations for PPI were the back, followed by the buttocks and heels. The PPI group was older and had a higher average comorbidity score ( P <.001). Comorbidity differences of those with and without PPI were observed in congestive heart failure (28.1% vs. 15.2%, P <.001), diabetes (28.5% vs. 19.2%, P <.001), renal disease (27.7% vs. 18.8%, P <.001), and severe liver disease (8.0% vs. 3.4%, P <.001). There were no differences in race, body mass index, or history of tobacco use between the PPI group and the non-PPI group.</p><p><strong>Conclusions: </strong>This study identified that cardiovascular surgery remains a high risk for PPI in perioperative patients. Among the demographic characteristics, race is not a sufficient category for identifying risk for PPI as it lacks the accuracy in skin tone measurement.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":"105-111"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145987763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantifying and Visualizing the Pressure Distribution of In-Bed Positions to Reduce Pressure Injury Risk.","authors":"Tim M N van Helden, Sarah L Versnel, Lisa Arkes, Mette Lindhout, Marc A M Mureau, Johan W van Neck","doi":"10.1097/ASW.0000000000000402","DOIUrl":"10.1097/ASW.0000000000000402","url":null,"abstract":"<p><strong>Objective: </strong>Pressure injuries (PIs) are a major health care issue, and timely and correct repositioning of patients at risk for PIs is crucial in lowering the PI risk. However, the ideal bed positions and the impact on the PI risk are often unclear to health care staff. Therefore, the authors used a pressure-detecting mat to quantify and visualize the effects of bed settings and body position on the pressure distribution to provide insightful graphics for educating health care staff.</p><p><strong>Methods: </strong>The authors quantitatively assessed and visualized the pressure distribution of different in-bed lying and sitting positions with a pressure-measuring mat on 2 different hospital mattresses by including healthy volunteers.</p><p><strong>Results: </strong>Differences between positions were visualized by the pressure mat. The median pressure on the sacrum increased by 30% to 35% when the head of bed (HOB) angle was raised from 0° to 30° and further increased 17% to 27% when the HOB angle was raised from 30° to 45°. Pressure on sacrum, when sitting with an HOB angle of 30°, reduced by 19% to 35% when raising the legs to semi-Fowler position. During lateral rotation, median pressure on the greater trochanter increased by 27% to 35% when rotating from 30° to 60°. Pressures are reported in a range between the 2 different mattresses.</p><p><strong>Conclusions: </strong>Pressure maps and peak pressure values of the different bed positions can help educate nurses on how body position changes the pressure distribution and provides additional support to follow the international guideline on PI prevention.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":"39 2","pages":"73-79"},"PeriodicalIF":1.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12893143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146257065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}