Sleep epidemiologyPub Date : 2022-12-01DOI: 10.1016/j.sleepe.2021.100017
Patrick Lemoine , David Ebert , Yoshihiko Koga , Claire Bertin
{"title":"Public interest and awareness regarding general health, sleep quality and mental wellbeing during the early COVID-19 pandemic period: An exploration using Google trends","authors":"Patrick Lemoine , David Ebert , Yoshihiko Koga , Claire Bertin","doi":"10.1016/j.sleepe.2021.100017","DOIUrl":"10.1016/j.sleepe.2021.100017","url":null,"abstract":"<div><p>The internet network continues to be a major source of health-related information. Our research provides insights into the online health-seeking behaviors of the general population, and evaluates the potential relationship between the COVID-19 pandemic and public interest and awareness of general sleep health, mental health and wellbeing.</p><p>Google Trends’ weekly relative search volumes (RSVs) were examined during 2020 for searches specifically related to COVID-19 symptoms, and for searches related to general health, sleep and wellbeing, in the United Kingdom, the United States of America, France, Italy and Japan. To obtain insight into the association between the initiation of public restrictions and online search trends, we assessed a six-week period; the ‘early pandemic period’ (EPP) (01 March 2020 – 11 April 2020). To provide a meaningful pre-pandemic comparison, a similar period during 2019 (03 March – 13 April 2019) was compared for RSV and median difference analysis.</p><p>The EPP was associated with increased online searches related to COVID-19 symptoms, as compared with those related to more general sleep health, mental health and wellbeing. The latter search terms frequently showed a decrease or minimal change in RSV during the EPP compared with the equivalent period in 2019. This finding illustrates the potential link between the COVID-19 pandemic and online search behavior and corroborates existing findings regarding internet searches during this period.</p><p>Proactive communication by healthcare professionals during future pandemics and as an ongoing measure could help prevent public neglect of general health and wellbeing symptoms, and encourage reporting and early intervention.</p></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"2 ","pages":"Article 100017"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10316726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sleep epidemiologyPub Date : 2022-12-01DOI: 10.1016/j.sleepe.2022.100044
Georg Nilius , Ulf Kallweit , Daniel Trümper , Tobias Vogelmann , Tino Schubert
{"title":"Prevalence, incidence, and characteristics of CPAP treated OSA patients with residual excessive daytime sleepiness, as indicated by health-related data – A population representative study","authors":"Georg Nilius , Ulf Kallweit , Daniel Trümper , Tobias Vogelmann , Tino Schubert","doi":"10.1016/j.sleepe.2022.100044","DOIUrl":"10.1016/j.sleepe.2022.100044","url":null,"abstract":"<div><h3>Purpose</h3><p>Excessive daytime sleepiness (EDS) is a symptom experienced by patients with obstructive sleep apnea (OSA) that may persist despite primary CPAP therapy (residual EDS; rEDS). This study aimed to estimate the age- and gender-specific prevalence and incidence for CPAP-treated OSA patients that showed indicators of rEDS in health-related data.</p></div><div><h3>Methods</h3><p>This study used the InGef research database, an anonymized representative dataset of 4 million persons covered by statutory health insurance in Germany. OSA patients receiving CPAP therapy were analyzed and data indicators for rEDS, or with EDS not satisfactorily treated by primary OSA therapy, were identified using an expert-opinion based diagnostic scheme in two study cohorts: The objective of the first cohort was to estimate the 12-month prevalence and incidence of rEDS in OSA (study period: 2016). The second cohort investigates patient characteristics and health care utilization (study period: 2013–2018).</p></div><div><h3>Results</h3><p>1298 OSA patients with indicators of rEDS after initiation of CPAP therapy were identified, giving an overall prevalence estimate of 41.1 (95%-CI 38.9-43.4) per 100,000 persons in Germany. Of all CPAP-users, 6.4% were affected by rEDS. Annual incidence was estimated to be 6.4 (95%-CI 5.6-7.4) per 100,000 persons. In the year before CPAP treatment started, 46% received antidepressants, 45% were in psychotherapeutic treatment and 58% of employees were unable to work, on average for 71 days within one year.</p></div><div><h3>Conclusion</h3><p>Patients that were identified with indicators of residual EDS showed a high socioeconomic burden potentially leading to an increased demand of healthcare services and incapacity for work.</p></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"2 ","pages":"Article 100044"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667343622000257/pdfft?md5=eb3ff705fd06c490586d0a9502a3690d&pid=1-s2.0-S2667343622000257-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44556622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sleep epidemiologyPub Date : 2022-12-01DOI: 10.1016/j.sleepe.2022.100038
Sophie Desjardins, Marjorie Grandbois
{"title":"Sleep parameters associated with university students’ grade point average and dissatisfaction with academic performance","authors":"Sophie Desjardins, Marjorie Grandbois","doi":"10.1016/j.sleepe.2022.100038","DOIUrl":"10.1016/j.sleepe.2022.100038","url":null,"abstract":"<div><p>The present study sought to determine which subjective sleep assessment parameters were most strongly associated with university students’ grade point average (GPA) and level of satisfaction with their academic performance. One hundred and five students completed the Pittsburgh Sleep Quality Index and answered questions about their GPA and level of satisfaction with that average. Logistic regression analyses indicate that the parameters most strongly associated with students’ GPA are, in descending order, sleep efficiency, daytime dysfunction due to sleepiness, and total sleep time. Only one parameter was associated with dissatisfaction with the GPA: subjective sleep quality. This study highlights the importance of considering students’ expectations of their academic performance rather than focusing solely on their grades. It also advocates for promoting high sleep efficiency rather than focusing exclusively or primarily on sleep duration.</p></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"2 ","pages":"Article 100038"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667343622000191/pdfft?md5=722bb131007a73e61cb3b9a311cdbc3d&pid=1-s2.0-S2667343622000191-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41714690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sleep epidemiologyPub Date : 2022-12-01DOI: 10.1016/j.sleepe.2022.100039
Jianghong Liu , Jan Magielski , Andrea Glenn , Adrian Raine
{"title":"The bidirectional relationship between sleep and externalizing behavior: A systematic review","authors":"Jianghong Liu , Jan Magielski , Andrea Glenn , Adrian Raine","doi":"10.1016/j.sleepe.2022.100039","DOIUrl":"10.1016/j.sleepe.2022.100039","url":null,"abstract":"<div><p>It is well-established that sleep and behavior are interrelated. Although studies have investigated this association, not many have evaluated the bidirectional relationship between the two. To our knowledge this is the first systematic review providing a comprehensive analysis of a reciprocal relationship between sleep and externalizing behavior. Five databases (PsycINFO, PubMed, Web of Science, Scopus, and Google Scholar) were utilized to yield a total of 3,762 studies of which 20 eligible studies, empirical articles examining bidirectionality of sleep and externalizing behavior, were selected for analysis. According to the guidelines of the Preferred Reporting Items for Systematic Review and Meta-Analysis, the varying methodological approaches used in these studies were analyzed and synthesized, including examining differences and similarities in outcomes between distinct study designs (longitudinal vs cross-sectional), sleep measures (objective vs subjective vs a combination of both), informants (parents, self-report, teachers), and recruited participants (clinical, subclinical and typical populations). The assessment of risk of bias and quality of studies was guided by the instruments employed in research on sleep and behavior in the past. This review establishes that a bidirectional relationship between sleep problems and externalizing behavior clearly exists, and identifies limitations in the existing literature. Furthermore, the importance of early interventions that target both externalizing behaviors and sleep problems is highlighted as a potentially effective way of breaking the sleep-externalizing behavior relationship. Nonetheless, causality cannot be claimed until more trials that manipulate sleep and evaluate changes in externalizing behavior are conducted.</p></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"2 ","pages":"Article 100039"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667343622000208/pdfft?md5=ece1204da13b8a839e9049790a100b1b&pid=1-s2.0-S2667343622000208-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48009864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sleep epidemiologyPub Date : 2022-12-01DOI: 10.1016/j.sleepe.2022.100021
Saana Myllyntausta , Erkki Kronholm , Anna Pulakka , Jaana Pentti , Marianna Virtanen , Sari Stenholm
{"title":"Associations of sleep and individual characteristics with accelerometer-measured catch-up sleep among older employees","authors":"Saana Myllyntausta , Erkki Kronholm , Anna Pulakka , Jaana Pentti , Marianna Virtanen , Sari Stenholm","doi":"10.1016/j.sleepe.2022.100021","DOIUrl":"10.1016/j.sleepe.2022.100021","url":null,"abstract":"<div><p>There is limited knowledge on the characteristics of employees who engage in catch-up sleep, the extension of sleep duration on free days to compensate for sleep loss accumulating during workdays. This study examined associations of accelerometer-measured free day catch-up sleep with sleep duration, sleep timing, and socio-demographic, health and lifestyle factors among older employees. We measured sleep repeatedly with accelerometers among 824 public sector employees in Finland (mean age 63 years; 86% women). On average, the participants provided 1.7 annual accelerometer measurements and 1,437 person-observations in total. Catch-up sleep was defined as longer average sleep duration on free days compared with average sleep duration on workdays. Prevalence of catch-up sleep was 78%. On average, the catch-up sleep group extended their sleep on free days by 1 hour 22 min (95% confidence interval [CI] 1 h 19 min – 1 h 26 min), whereas the non-catch-up sleep group reduced their sleep duration by 45 min (95% CI -50 min – -40 min). Catch-up sleep was mainly associated with delayed awakening time on free days (by 1 h 57 min, 95% CI 1 h 52 min – 2 h 2 min). We also observed a greater social jetlag in the catch-up sleep group in comparison to the non-catch-up sleep group, whereas no differences were observed in chronotype, self-reported sleep, or other individual characteristic. In conclusion, accelerometer-measured catch-up sleep is common among older employees in Finland and major differences in duration and timing of sleep occur between those with and without catch-up sleep.</p></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"2 ","pages":"Article 100021"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667343622000026/pdfft?md5=fc062e81a9f9113b31a950a2ca4b170a&pid=1-s2.0-S2667343622000026-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49126505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sleep epidemiologyPub Date : 2022-12-01DOI: 10.1016/j.sleepe.2022.100042
Lacey W. Heinsberg , Jenna C. Carlson , Alysa Pomer , Brian E. Cade , Take Naseri , Muagututia Sefuiva Reupena , Daniel E. Weeks , Stephen T. McGarvey , Susan Redline , Nicola L. Hawley
{"title":"Correlates of daytime sleepiness and insomnia among adults in Samoa","authors":"Lacey W. Heinsberg , Jenna C. Carlson , Alysa Pomer , Brian E. Cade , Take Naseri , Muagututia Sefuiva Reupena , Daniel E. Weeks , Stephen T. McGarvey , Susan Redline , Nicola L. Hawley","doi":"10.1016/j.sleepe.2022.100042","DOIUrl":"10.1016/j.sleepe.2022.100042","url":null,"abstract":"<div><h3>Objective</h3><p>To describe daytime sleepiness and insomnia among adults in Samoa and identify modifiable factors associated with these measures.</p></div><div><h3>Design/setting</h3><p>Cross-sectional analysis of data from the <em>Soifua Manuia</em> (“Good Health”) study (<em>n</em> = 519, 55.1% female); Upolu island, Samoa.</p></div><div><h3>Methods</h3><p>Daytime sleepiness and insomnia were assessed with the Epworth Sleepiness Scale (ESS) and the Women's Health Initiative Insomnia Rating Scale (WHIIRS), respectively. Detailed physical, sociodemographic, and behavioral factors were collected. Sleep measures were characterized using multiple linear regression with backwards elimination and a bootstrap stability investigation.</p></div><div><h3>Results</h3><p>Excessive daytime sleepiness (ESS>10) and insomnia (WHIIRS>10) were reported by 20% and 6.3% of the sample, respectively. ESS scores were higher in individuals reporting more physical activity (Estimate=1.88; 95% CI=1.12 to 2.75), higher material wealth (0.18; 0.09 to 0.28), and asthma (2.85; 1.25 to 4.51). ESS scores were lower in individuals residing in periurban versus urban regions (-1.43; -2.39 to -0.41), reporting no work versus day shift work (-2.26; -3.07 to -1.41), and reporting greater perceived stress (-0.14; -0.23 to -0.06). WHIIRS scores were lower in individuals reporting “other” shift work (split/irregular/on-call/rotating) versus day shift work (-1.96; -2.89 to -1.14) and those who perceived their village's wealth to be poor/average versus wealthy (-0.94; -1.50 to -0.34).</p></div><div><h3>Conclusions</h3><p>Participants had a generally higher prevalence of excessive daytime sleepiness, but lower prevalence of insomnia, compared with individuals from high-income countries. Factors associated with sleep health differed compared with prior studies, emphasizing potential cultural/environmental differences and the need for targeted interventions to improve sleep health in this setting.</p></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"2 ","pages":"Article 100042"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cf/2a/nihms-1829854.PMC9635619.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9163634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sleep epidemiologyPub Date : 2022-12-01DOI: 10.1016/j.sleepe.2022.100034
Adriana Kramer Fiala Machado, Luiza Isnardi Cardoso Ricardo, Andrea Wendt, Fernando Cesar Wehrmeister
{"title":"Association between sleep duration and academic, cognitive and socioeconomic outcomes: A systematic literature review of population-based studies","authors":"Adriana Kramer Fiala Machado, Luiza Isnardi Cardoso Ricardo, Andrea Wendt, Fernando Cesar Wehrmeister","doi":"10.1016/j.sleepe.2022.100034","DOIUrl":"10.1016/j.sleepe.2022.100034","url":null,"abstract":"<div><h3>Purpose</h3><p>The aim of this study was to systematically review the literature about the relationship between sleep duration and cognitive, academic and socioeconomic outcomes.</p></div><div><h3>Methods</h3><p>We performed a systematic search in PubMed, Psyinfo, Scopus, Web of Science, ERIC, and Socindex up to June 2022, independently by two researchers. Original studies testing the association between sleep duration (as exposure) and academic, cognitive and socioeconomic variables (as outcomes) among all age groups in population-based studies were included. We excluded studies assessing participants with specific diseases or specific populations. Quality assessment was evaluated considering three domains: internal validity, study design, and adjustments.</p></div><div><h3>Results</h3><p>After the study selection process, a total of 56 manuscripts were selected. Most studies were from high-income countries with a large variability of instruments and cutoff points to measure sleep duration and outcomes. Cognitive outcomes were evaluated in 35 manuscripts, academic outcomes in 22, and socioeconomic outcomes in one. Long sleep seems to be associated with poor cognitive outcomes in older adults. In contrast, short sleep duration seems to be associated with poor cognitive and school outcomes among children and adolescents. Studies evaluating cognition in children and adolescents and academic outcomes presented lower scores in the quality assessment.</p></div><div><h3>Conclusion</h3><p>More well designed and well-adjusted studies evaluating cognitive and academic outcomes in children, adolescents, and mainly, in adult population are necessary. Furthermore, studies from low- and middle- income countries, evaluating sleep duration and exploring the relationship between sleep duration as exposure variable and human capital characteristics as outcomes variables should be included in the research agenda.</p></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"2 ","pages":"Article 100034"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667343622000154/pdfft?md5=fbce52b4d7e75b184016339d54d18762&pid=1-s2.0-S2667343622000154-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41475592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sleep epidemiologyPub Date : 2022-12-01DOI: 10.1016/j.sleepe.2022.100024
Mandy Pascalle Glasbeek , Maj-Britt Merel Ragnhild Inhulsen , Vincent Busch , Maartje Marieke van Stralen
{"title":"Sleep reduction in adolescents: socio-demographic factors and the mediating role of sleep hygiene practices","authors":"Mandy Pascalle Glasbeek , Maj-Britt Merel Ragnhild Inhulsen , Vincent Busch , Maartje Marieke van Stralen","doi":"10.1016/j.sleepe.2022.100024","DOIUrl":"10.1016/j.sleepe.2022.100024","url":null,"abstract":"<div><h3>Objectives</h3><p>This study examined socio-demographic factors of sleep reduction in adolescents and whether differences in sleep reduction were mediated by their sleep hygiene practices. It also provides more insight into the prevalence of sleep reduction in a sample of Dutch adolescents.</p></div><div><h3>Design</h3><p>Cross-sectional study using baseline data from the cluster-randomized controlled trial Charge Your Brainzzz.</p></div><div><h3>Participants</h3><p>972 adolescents in the second or third grade of secondary school, aged 13.3 (± 0.7) years, of which 55% were girls.</p></div><div><h3>Methods</h3><p>Socio-demographic differences (gender, age, education types, cultural groups) in sleep reduction and the mediating effects of sleep hygiene practices (i.e., caffeine use, behavioral arousal, cognitive/emotional arousal) were assessed with linear regression analyses and the product-of-coefficient test with percentile-based confidence intervals, respectively. Sleep reduction was measured using the Sleep Reduction Screening Questionnaire, whereas sleep hygiene practices were measured via the Adolescent Sleep Hygiene Scale.</p></div><div><h3>Results</h3><p>33% of adolescents reported sleep reduction. Girls and older-aged adolescents experienced more sleep reduction than boys and younger-aged adolescents, respectively. The association between gender and sleep reduction was mediated by cognitive/emotional arousal but suppressed by caffeine use, while behavioral arousal and cognitive/emotional arousal mediated the association between age and sleep reduction.</p></div><div><h3>Conclusions</h3><p>Sleep reduction was shown to be common in Dutch adolescents, especially in girls and older-aged adolescents. Sleep hygiene practices partly explained the differences in sleep health and sleep reduction between different socio-demographic risk groups. Further research is needed to provide more insight into the complexity of sleep reduction and its interrelated behaviors and risk factors.</p></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"2 ","pages":"Article 100024"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667343622000051/pdfft?md5=24040f196534e103a7d4a9c7d6000c6d&pid=1-s2.0-S2667343622000051-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47965058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sleep epidemiologyPub Date : 2022-12-01DOI: 10.1016/j.sleepe.2022.100027
Karen Spruyt
{"title":"Sleep problems in individuals with Rett Syndrome: A systematic review and meta-analysis","authors":"Karen Spruyt","doi":"10.1016/j.sleepe.2022.100027","DOIUrl":"10.1016/j.sleepe.2022.100027","url":null,"abstract":"<div><h3>Importance</h3><p>Prognosis and understanding of sleep disorders in rare genetic syndromes is limited, despite being a common complaint of caregivers. Rett Syndrome (RTT) is a rare, progressive neurodevelopmental disorder with problematic sleeping being a clinical feature yet inconsistencies exist in the literature.</p></div><div><h3>Objective</h3><p>To examine the strength of evidence of a sleep disorder in RTT. To investigate the complaints reported based on a sleep disorders classification approach and to determine differences in rates per the RTT main clinical features.</p></div><div><h3>Data sources</h3><p>PubMed, Web of Science, PsycINFO, Ebsco, Scopus, and Cochrane Library up to November 4<sup>th</sup> 2021 with no time or language limitation (CRD 42020198099) were searched.</p></div><div><h3>Study selection</h3><p>Original research published in peer-reviewed journals, with RTT clinical or genetic diagnosis reported and stating a sleep complaint with prevalence rate, were selected.</p></div><div><h3>Data Extraction and Synthesis</h3><p>We followed the PRISMA guideline for abstracting data and assessed risk of bias with the NIH quality assessment tools. The prevalence rates were meta-analyzed applying the mixed-effects model with measures of consistency.</p></div><div><h3>Main Outcome(s) and Measure(s)</h3><p>The International Classification of Sleep Disorders was used to summarize sleep complaints reported in the literature. Those that did not specify the precise sleep complaint were categorized as a not otherwise specified sleep problem. We further analyzed data per available RTT characteristics.</p></div><div><h3>Results</h3><p>We included 19 studies (<em>n</em> = 4298, 0.3 to 57.2 years old) across five countries involving predominantly observational study designs. Overall, 54.1% (95%CI: 43.8% to 64.5%) of individuals with RTT exhibit problematic sleeping, in particular, excessive somnolence (67.5%; 95%CI: 47.5% to 82.7%) and difficulties initiating and maintaining sleep (61%; 95%CI: 49.6% to 71.4%). Disturbed sleep not otherwise specified was reported in 57.1% (95%CI: 34.5% to 81.3%). Although studies could improve details reported, females with <em>MECP2</em>-RTT showed a higher prevalence rate of excessive somnolence and sleep-wake transition disorders than those diagnosed by <em>CDKL5</em>-RTT. <strong>P</strong>revalence rates remain roughly unaltered across the lifespan. Sleep disorders are about two times more prevalent than in typically developing children.</p></div><div><h3>Conclusions and Relevance</h3><p>Findings indicate predominantly disorders regarding maintenance of sleep and wake state, which persist throughout their lifespan. Improved reporting of clinical features in cases with RTT phenotypes and of sleep behavior frequency and severity may lead to explicit prevalence rates. This is fundamental to progress in the pathophysiological investigation of altered sleep-wake mechanisms and to implement tailored sleep ","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"2 ","pages":"Article 100027"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667343622000087/pdfft?md5=9201fc265368ab88dbc58dc7b378d374&pid=1-s2.0-S2667343622000087-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43592613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. W. Heinsberg, J. Carlson, A. Pomer, B. Cade, T. Naseri, M. Reupena, D. Weeks, S. McGarvey, S. Redline, N. Hawley
{"title":"Correlates of daytime sleepiness and insomnia among adults in Samoa","authors":"L. W. Heinsberg, J. Carlson, A. Pomer, B. Cade, T. Naseri, M. Reupena, D. Weeks, S. McGarvey, S. Redline, N. Hawley","doi":"10.1101/2022.05.25.22275570","DOIUrl":"https://doi.org/10.1101/2022.05.25.22275570","url":null,"abstract":"Objective: To describe daytime sleepiness and insomnia among adults in Samoa and identify modifiable factors associated with these measures. Design/setting: Cross-sectional analysis of data from the Soifua Manuia (Good Health) study (n=519, 55.1% female); Upolu island, Samoa. Methods: Daytime sleepiness and insomnia were assessed with the Epworth Sleepiness Scale (ESS) and the Women's Health Initiative Insomnia Rating Scale (WHIIRS), respectively. Detailed physical, sociodemographic, and behavioral factors were collected. Sleep measures were characterized using multiple linear regression with backwards elimination and a bootstrap stability investigation. Results: Excessive daytime sleepiness (ESS>10) and insomnia (WHIIRS>10) were reported by 20% and 6.3% of the sample, respectively. ESS scores were higher in individuals reporting more physical activity (Estimate=1.88; 95% CI=1.12 to 2.75), higher material wealth (0.18; 0.09 to 0.28), and asthma (2.85; 1.25 to 4.51). ESS scores were lower in individuals residing in periurban versus urban regions (-1.43; -2.39 to -0.41), reporting no work versus day shift work (-2.26; -3.07 to -1.41), and reporting greater perceived stress (-0.14; -0.23 to -0.06). WHIIRS scores were lower in individuals reporting other shift work (split/irregular/on-call/rotating) versus day shift work (-1.96; -2.89 to -1.14) and those who perceived their village's wealth to be poor/average versus wealthy (-0.94; -1.50 to -0.34). Conclusions: Participants had a generally higher prevalence of excessive daytime sleepiness, but lower prevalence of insomnia, compared with individuals from high-income countries. Factors associated with sleep health differed compared with prior studies, emphasizing potential cultural/environmental differences and the need for targeted interventions to improve sleep health in this setting.","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45171516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}