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Tirzepatide for Night Eating Syndrome (NES) and Sleep-Related Eating Disorder (SRED): a presentation of two cases 替西帕肽治疗夜间进食综合征(NES)和睡眠相关进食障碍(SRED):两例报告
Sleep epidemiology Pub Date : 2026-12-01 Epub Date: 2026-01-18 DOI: 10.1016/j.sleepe.2026.100128
Kammi J Grayson, Melissa Russell, Rebecca Q Scott, Alcibiades J Rodriguez
{"title":"Tirzepatide for Night Eating Syndrome (NES) and Sleep-Related Eating Disorder (SRED): a presentation of two cases","authors":"Kammi J Grayson,&nbsp;Melissa Russell,&nbsp;Rebecca Q Scott,&nbsp;Alcibiades J Rodriguez","doi":"10.1016/j.sleepe.2026.100128","DOIUrl":"10.1016/j.sleepe.2026.100128","url":null,"abstract":"<div><div>Tirzepatide is a glucagon-like peptide-1 (GLP-1) receptor agonist and glucose-dependent insulinotropic polypeptide (GIP) analog approved for treatment of Type 2 Diabetes Mellitus, obesity and moderate-to-severe obstructive sleep apnea in patients with obesity. The role of the GLP-1 drugs in treating eating disorders is unclear. Night Eating Syndrome (NES) and Sleep-Related Eating Disorder (SRED) are conditions in which sleep parasomnias and eating behaviors overlap. Their treatment remains challenging and includes cognitive behavioral therapy and pharmacotherapy using topiramate, selective serotonin reuptake inhibitors, or anorectic serotonergic medications. We report two cases of NES, one of them with comorbid SRED, treated successfully with tirzepatide.</div></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"6 ","pages":"Article 100128"},"PeriodicalIF":0.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146037757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep quality in medical students: Any relationship with fatigue severity? 医学生的睡眠质量:与疲劳程度有关系吗?
Sleep epidemiology Pub Date : 2026-12-01 Epub Date: 2025-12-07 DOI: 10.1016/j.sleepe.2025.100126
Rozan Can Acar , Ece Acan , Ozan Kaan Konak , Ozen K Basoglu
{"title":"Sleep quality in medical students: Any relationship with fatigue severity?","authors":"Rozan Can Acar ,&nbsp;Ece Acan ,&nbsp;Ozan Kaan Konak ,&nbsp;Ozen K Basoglu","doi":"10.1016/j.sleepe.2025.100126","DOIUrl":"10.1016/j.sleepe.2025.100126","url":null,"abstract":"<div><h3>Background</h3><div>Sixth-year medical students (interns) experience intense working conditions and need to prepare for medical specialization examination. All these stress factors negatively affect students’ sleep quality.</div></div><div><h3>Methods</h3><div>An online survey was conducted in 223 out of 534 interns between April and July 2023 in a university hospital in Türkiye. Sleep quality, fatigue and stress levels were evaluated by Pittsburgh Sleep Quality Index (PSQI), Chalder Fatigue Scale (CFS) and Visual Analogue Scale (VAS), respectively (PSQI &gt;5, CFS ≥29, VAS 6.78 ± 1.82 (range 0–10), with higher values indicating greater momentary perceived stress.).</div></div><div><h3>Results</h3><div>Out of 223 interns (46.1% women, mean age 24 years), 177 (79.4%) had poor sleep quality. Moderate or high fatigue severity was observed in 94.4% of the students with poor sleep quality, whereas only 52.2% of those with good sleep quality had moderate fatigue risk (p&lt;0.001). Participants with poor sleep quality had lower incomes (p=0.002), higher stress levels (p=0.005) and higher fatigue scores (p=0.001) compared to those with good sleep quality. Additionally, low socioeconomic status (odds ratio [OR], 25.625, 95% confidence interval [CI] 3.313-98.196; p=0.002), increased stress levels (OR, 2.838, CI 1.369-5.882; p=0.005), high stress (OR, 2.053, CI 1.051-4.010; p=0.035), and fatigue severity (OR, 15.308, CI 6.470-36.223; p&lt;0.001) were associated with poor sleep quality.</div></div><div><h3>Conclusion</h3><div>Most of the interns (79.4%), working under demanding conditions, had poor sleep quality, leading to increased risk of fatigue severity. Low incomes and high stress levels were predictors of poor sleep quality.</div></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"6 ","pages":"Article 100126"},"PeriodicalIF":0.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145718985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Psychometric Framework for Modeling the impact of Insomnia on Academic Performance 一个模拟失眠症对学习成绩影响的心理测量框架
Sleep epidemiology Pub Date : 2026-12-01 Epub Date: 2025-12-16 DOI: 10.1016/j.sleepe.2025.100127
Shireen Fathima, Maaz Ahmed
{"title":"A Psychometric Framework for Modeling the impact of Insomnia on Academic Performance","authors":"Shireen Fathima,&nbsp;Maaz Ahmed","doi":"10.1016/j.sleepe.2025.100127","DOIUrl":"10.1016/j.sleepe.2025.100127","url":null,"abstract":"<div><div>Insomnia is increasingly prevalent among university students, adversely affecting both academic performance and psychological well being. This study presents a comprehensive behavioral modeling framework linking sleep disruption to academic outcomes using self reported psychometric data from 996 undergraduate students across all four academic years. The dataset captured sleep patterns, lifestyle factors, stress, and academic performance indicators through a structured questionnaire survey. A significant negative correlation was observed between sleep disturbances and GPA. Unsupervised clustering of sleep and lifestyle features revealed distinct behavioral subgroups, while supervised classifiers validated through both 80/20 train–test split and 3-fold cross-validation achieved strong predictive performance (AUC = 0.96, F1 = 0.89). Permutation based feature importance identified sleep-onset difficulty, perceived stress, and caffeine consumption as dominant predictors of academic decline. These findings demonstrate the value of integrating psychometric assessment with machine learning to identify students at academic risk and provide a foundation for data-driven interventions in higher education.</div></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"6 ","pages":"Article 100127"},"PeriodicalIF":0.0,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145791657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding Latine disparities in nocturnal wakefulness as a suicide risk factor 了解拉丁人夜间清醒的差异作为自杀风险因素
Sleep epidemiology Pub Date : 2025-12-01 Epub Date: 2025-09-24 DOI: 10.1016/j.sleepe.2025.100117
Fabian-Xosé Fernandez , Andrew S. Tubbs , Michael L. Perlis , Michael A. Grandner
{"title":"Understanding Latine disparities in nocturnal wakefulness as a suicide risk factor","authors":"Fabian-Xosé Fernandez ,&nbsp;Andrew S. Tubbs ,&nbsp;Michael L. Perlis ,&nbsp;Michael A. Grandner","doi":"10.1016/j.sleepe.2025.100117","DOIUrl":"10.1016/j.sleepe.2025.100117","url":null,"abstract":"<div><div>Individuals who remain awake during hours typically reserved for sleep exhibit a significantly elevated risk (1.2 to 7.2-fold) of suicidal ideation, behaviours, or death, varying according to the specific hour of nocturnal wakefulness. This association has been robustly replicated across diverse populations and within individual assessments. Notably, Hispanic/Latine adults demonstrate a 26–45% stronger relationship between nighttime wakefulness and suicide risk compared to other groups, resulting in a disproportionately higher occurrence of nighttime suicides, despite lower overall suicide rates. We previously proposed the \"Mind after Midnight\" (MaM) hypothesis, suggesting that the interplay between accumulating sleep pressure and circadian modulation impairs decision-making and emotional regulation during nighttime, thus heightening vulnerability to maladaptive behaviours, including suicide. In this manuscript, we summarize evidence supporting the MaM hypothesis and propose two mechanisms potentially underpinning the heightened nocturnal suicide risk among Latine adults. First, cultural values emphasizing social connectedness may amplify vulnerability to social isolation during nighttime wakefulness. Second, existing social disadvantages may increase nocturnal wakefulness and exacerbate the psychological impact of daily stressors experienced during these periods. Given that Hispanic/Latine individuals represent one of the largest and fastest-growing minority populations in the United States—and considering Mexican Americans, a significant subgroup, report the greatest reductions in sleep duration among racial/ethnic groups—our findings underscore the critical need to verify whether nocturnal wakefulness disproportionately increases suicidal ideation and behaviours in this demographic. Confirmation of these relationships could inform culturally tailored interventions aimed at reducing suicide risk within the broader Latine community.</div></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"5 ","pages":"Article 100117"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145227116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two-year CPAP adherence in obstructive sleep apnea patients in Vietnam: the first prospective cohort 越南阻塞性睡眠呼吸暂停患者坚持两年CPAP:第一个前瞻性队列
Sleep epidemiology Pub Date : 2025-12-01 Epub Date: 2025-11-16 DOI: 10.1016/j.sleepe.2025.100123
Phan Thanh Thuy , Vu Van Giap
{"title":"Two-year CPAP adherence in obstructive sleep apnea patients in Vietnam: the first prospective cohort","authors":"Phan Thanh Thuy ,&nbsp;Vu Van Giap","doi":"10.1016/j.sleepe.2025.100123","DOIUrl":"10.1016/j.sleepe.2025.100123","url":null,"abstract":"<div><h3>Background</h3><div>Long-term adherence to continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea (OSA) often falls below 30 %. We report the first two-year evaluation of CPAP adherence among Vietnamese patients with moderate to severe OSA.</div></div><div><h3>Methods</h3><div>In this prospective cohort, 32 treatment-naïve adults (Apnea–hypopnea index -AHI ≥ 15 events/h) were enrolled following in-lab polysomnography. Adherence was defined as ≥ 4 h/night on ≥ 70 % of nights over any 30-day period. CPAP monitoring and usage parameters (apnea-hypopnea index - residual AHI, compliance, adherence, P95 pressure- Mean 95th percentile CPAP pressure, air leakage) were recorded at 1, 3, 6, 9, 12, and 24 months. Predictors of long-term adherence were analyzed using correlation models.</div></div><div><h3>Results</h3><div>All 32 participants completed follow-up. Adherence rates were 65.6 % at 1 month, 53.1 % at 3 months, 46.9 % at 6, 9, and 12 months, and 50.0 % at 24 months. Mean AHI fell from 56.3 ± 18.2 to 2.9 ± 2.8 events/h after one month (<em>p</em> &lt; 0.001) and remained stable. Higher baseline AHI, obstructive apnea index, and apnea duration, lower mean SpO₂, and good 3-month adherence were all significantly associated with sustained use at two years.</div></div><div><h3>Conclusions</h3><div>Approximately half of Vietnamese patients with moderate to severe OSA remain adherent to CPAP after two years. Both initial disease severity and early treatment adherence independently predict long-term adherence, underscoring the importance of close monitoring and intervention during the first three months of therapy.</div></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"5 ","pages":"Article 100123"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145579018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Sleep disturbances in Morocco: A population-based study 摩洛哥睡眠障碍患病率:一项基于人群的研究
Sleep epidemiology Pub Date : 2025-12-01 Epub Date: 2025-10-28 DOI: 10.1016/j.sleepe.2025.100120
Abderrahmane Chahidi , Marouane Mergaoui , Said Boujraf , Najat Belarbi , Zouhayr Souirti
{"title":"Prevalence of Sleep disturbances in Morocco: A population-based study","authors":"Abderrahmane Chahidi ,&nbsp;Marouane Mergaoui ,&nbsp;Said Boujraf ,&nbsp;Najat Belarbi ,&nbsp;Zouhayr Souirti","doi":"10.1016/j.sleepe.2025.100120","DOIUrl":"10.1016/j.sleepe.2025.100120","url":null,"abstract":"<div><h3>Introduction</h3><div>Sleep disturbances negatively impact individuals’ physical, psychological, and social health and individual performance. This study aimed to examine the prevalence of sleep disturbances in Morocco as its primary objective and the related risk factors as a secondary objective, using a sample of 1010 participants from seven Moroccan regions selected for their population density and socio-cultural diversity.</div></div><div><h3>Participants and methods</h3><div>Participants were interviewed over the telephone by an accredited expert call center. Information on sleep disturbances and habits was collected using sleep disturbance questionnaires, which distinguish two main sleep disturbances: insomnia symptoms and excessive daytime sleepiness. Logistic regression models were used for risk factors.</div></div><div><h3>Results</h3><div>We collected data from 1,010 participants, yielding a response rate of 61.77 %. The mean age was 44.90 (±16.09) years (range: 18-96), with a female preponderance (78 %). Insomnia symptoms prevalence rate reached 30.2 % (95 % CI: 27.4–33.1), and the excessive daytime sleepiness prevalence rate was 17.9 % (95 % CI: 15.7–20.4). Among sociodemographic parameters (age, sex, educational level, and comorbidities), the female sex and educational level were associated with a higher prevalence of sleep disturbances.</div></div><div><h3>Conclusions</h3><div>Insomnia symptoms (30.2 %) were the most prevalent sleep disturbances. Its prevalence was higher among females (33.4 %; 95 % CI: 30.2–36.7) than males (18.9 %; 95 % CI: 14.3–24.6). Similarly, for excessive daytime sleepiness, the prevalence was higher among females (19.8 %; 95 % CI: 17.2–22.7) than males (11.3 %; 95 % CI: 7.7–16.1).</div></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"5 ","pages":"Article 100120"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145473724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High burden of moderate-to-severe obstructive sleep apnea: comparative accuracy of screening tools against polysomnography 中度至重度阻塞性睡眠呼吸暂停的高负担:多导睡眠图筛选工具的相对准确性
Sleep epidemiology Pub Date : 2025-12-01 Epub Date: 2025-09-10 DOI: 10.1016/j.sleepe.2025.100114
Asmaa Ali , Liang Wu , Seham Ezzat Fathy Elfeky , Mohammad H. Alhassoon , Dhuha S. Aldrees , Eman M. Moazen , Abdulaziz Alghulayqah , Mai M. Saleh
{"title":"High burden of moderate-to-severe obstructive sleep apnea: comparative accuracy of screening tools against polysomnography","authors":"Asmaa Ali ,&nbsp;Liang Wu ,&nbsp;Seham Ezzat Fathy Elfeky ,&nbsp;Mohammad H. Alhassoon ,&nbsp;Dhuha S. Aldrees ,&nbsp;Eman M. Moazen ,&nbsp;Abdulaziz Alghulayqah ,&nbsp;Mai M. Saleh","doi":"10.1016/j.sleepe.2025.100114","DOIUrl":"10.1016/j.sleepe.2025.100114","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Timely diagnosis of obstructive sleep apnea (OSA) is essential, but polysomnography (PSG) is resource intensive. Simple screening tools may aid triage, yet their comparative accuracy in high-risk populations remains unclear. This study aimed to assess OSA burden and evaluate the diagnostic performance of three tools (STOP-BANG, Epworth Sleepiness Scale (ESS), and NoSAS) against PSG, along with a Combined Screening Model (CSM) integrating these tools.</div></div><div><h3>Methods</h3><div>In this cross-sectional study, 140 patients referred for overnight PSG were screened using STOP-BANG, ESS, and NoSAS. Sensitivity, specificity, predictive values, and area under the receiver operating characteristic curve (AUC) were calculated using an apnea–hypopnea index (AHI) ≥5 events/h and oxygen desaturation index (ODI) ≥5 events/h as diagnostic thresholds. A CSM was developed to assess the combined predictive value.</div></div><div><h3>Results</h3><div>OSA was confirmed in 91% of patients, with 74% having moderate-to-severe disease. NoSAS had the highest AUC (0.70), followed by STOP-BANG (0.67), CSM (0.65), and ESS (0.61), with no significant differences. CSM showed the greatest sensitivity (71%), while NoSAS had the highest specificity (64%).</div></div><div><h3>Conclusion</h3><div>OSA was highly prevalent and often severe in this referral population. NoSAS performed slightly better individually, and combined models showed potential for supporting early triage. However, PSG remains essential for definitive diagnosis and management.</div></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"5 ","pages":"Article 100114"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between sleep problems and depressive symptoms among small-scale miners in Ghana 加纳小型矿工睡眠问题与抑郁症状之间的关系
Sleep epidemiology Pub Date : 2025-12-01 Epub Date: 2025-08-09 DOI: 10.1016/j.sleepe.2025.100112
Emmanuel Nyaaba , Emma AO. Sefa , Vanessa F. Epis , Lawrence Guodaar , Razak M. Gyasi
{"title":"Association between sleep problems and depressive symptoms among small-scale miners in Ghana","authors":"Emmanuel Nyaaba ,&nbsp;Emma AO. Sefa ,&nbsp;Vanessa F. Epis ,&nbsp;Lawrence Guodaar ,&nbsp;Razak M. Gyasi","doi":"10.1016/j.sleepe.2025.100112","DOIUrl":"10.1016/j.sleepe.2025.100112","url":null,"abstract":"<div><h3>Objective</h3><div>Sleep problems (SP) are increasingly linked to poor mental health outcomes, yet limited research has explored this association among high-risk occupational groups in low- and middle-income countries (LMICs). We investigate the association between SP and depressive symptoms among small-scale miners in Ghana and explores whether emotional distress and anxiety explain this association.</div></div><div><h3>Methods</h3><div>We recruited 664 miners (mean age = 28.8, SD = 8.2 years; males = 84.3 %) in this study. SP was assessed using the WHO Disability Assessment Schedule 2.0 (WHODAS 2.0), while depressive symptoms were measured using the PHQ-9. Emotional distress and anxiety were assessed using the MOS SF-36 scale and the GAD-7 scale, respectively. Multiple linear regressions and bootstrapping techniques evaluated the hypothesized direct and indirect associations.</div></div><div><h3>Results</h3><div>SP was significantly associated with higher levels of depressive symptoms (B = 0.171, p &lt; 0.001), after adjustment. Crucially, emotional distress (53.06 %; B = 0.2447, 95 % CI [0.1739, 0.3221]), and anxiety (25.0 %; B = 0.1153, 95 % CI [0.0592, 0.1745]) partially accounted for the association between SP and depressive symptoms.</div></div><div><h3>Conclusions</h3><div>Poor sleep quality may be a clinical marker for depressive symptoms among small-scale miners, with emotional distress and anxiety as key psychological pathways. Integrated sleep-related screening and intervention strategies is needed in poor occupational health settings. Nevertheless, given the non-probability sampling approach used, some degree of selection bias cannot be ruled out, and findings should be interpreted with caution regarding their generalizability beyond the study communities.</div></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"5 ","pages":"Article 100112"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144841472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Longitudinal study of chronic nausea and vomiting and its associations with sleep-related leg cramps in the US general population 美国普通人群慢性恶心和呕吐及其与睡眠相关腿痉挛的关联的纵向研究
Sleep epidemiology Pub Date : 2025-12-01 Epub Date: 2024-12-09 DOI: 10.1016/j.sleepe.2024.100103
MM Ohayon , YJ Chen , R Fass , ML Cote
{"title":"Longitudinal study of chronic nausea and vomiting and its associations with sleep-related leg cramps in the US general population","authors":"MM Ohayon ,&nbsp;YJ Chen ,&nbsp;R Fass ,&nbsp;ML Cote","doi":"10.1016/j.sleepe.2024.100103","DOIUrl":"10.1016/j.sleepe.2024.100103","url":null,"abstract":"<div><h3>Introduction</h3><div>Chronic nausea and vomiting (CNV) can have a long-term impact on people's health and quality of life. This study aims to investigate whether CNV is involved in the development of sleep-related leg cramps (SRLCs) in a longitudinal study involving 10,931 participants representative of the US general population.</div></div><div><h3>Methods</h3><div>Participants were interviewed three years apart over the telephone using the Sleep-EVAL expert system. It collected information on sleep habits/disturbances (International Classification of Sleep Disorders), mental disorders (DSM-IV-TR) and medical conditions. CNV was defined as episodes of nausea and vomiting occurring at least five times a month for at least one month (outside pregnancy) as per the ROME IV recommendations.</div></div><div><h3>Results</h3><div>At the initial interview, 3% (95%CI:2.7%-3.3%) of the participants reported CNV, and 2.5% (95%CI:2.2%-2.8%) at follow-up. The 3-year incidence for CNV was 1.4%. SRLCs was found in 12.4% (95%CI:11.9%-13.1%) of the sample at the first-interview and 11.5% (95%CI:10.1%-12.1%) at follow-up. Multivariate models show that individuals with CNV at both interviews had a relative risk 4.1 times higher (95%CI:2.7–6.2; <em>p</em> &lt; 0.0001) to have SRLCs at follow-up compared to those without nausea or vomiting. Magnesium intake at the initial interview was a protective factor for SRLCs (RR 0.4; 95%CI: 0.2–0.7; <em>p</em> = 003).</div></div><div><h3>Discussion</h3><div>Symptoms of CNV lasting for years is highly predictive of SRLC based on this longitudinal survey. The link between the two pathologies could be partially explained by potential potassium/magnesium depletion from muscles as a result of CNV. The findings of this study call for physician awareness of the association between CNV and SRLC.</div></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"5 ","pages":"Article 100103"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of sleep disturbances and factors associated among school going children in Uganda, a cross-sectional study 乌干达学龄儿童睡眠障碍患病率及其相关因素,一项横断面研究
Sleep epidemiology Pub Date : 2025-12-01 Epub Date: 2024-12-09 DOI: 10.1016/j.sleepe.2024.100104
Baluku Reagan Innocent , Oriokot Lorraine , Elly Katabira , Martha Sajatovic , Abbo Catherine , Kaddumukasa Mark
{"title":"Prevalence of sleep disturbances and factors associated among school going children in Uganda, a cross-sectional study","authors":"Baluku Reagan Innocent ,&nbsp;Oriokot Lorraine ,&nbsp;Elly Katabira ,&nbsp;Martha Sajatovic ,&nbsp;Abbo Catherine ,&nbsp;Kaddumukasa Mark","doi":"10.1016/j.sleepe.2024.100104","DOIUrl":"10.1016/j.sleepe.2024.100104","url":null,"abstract":"<div><h3>Background</h3><div>Sleep disturbances greatly impact children's academic performance and social well-being. This study set out to determine the prevalence of sleep disturbances and factors associated among school going children in Kawempe division, Kampala, Uganda.</div></div><div><h3>Methods</h3><div>In a community cross-sectional study, 548 study participants using random cluster sampling were enrolled. The children start lessons at 8am and end the days classes at 5pm. Random cluster sampling method was used to select participants from the 19 parishes in Kawempe district. Data was collected using a semi-structured questionnaire and Sleep Disturbance Scale for Children (SDSC). Descriptive statistics and multivariate binary logistic regression were performed with a <em>p</em> &lt; 0.05 level of significance, and a 95 % confidence interval as a measure of association between the sleep disturbance.</div></div><div><h3>Results</h3><div>Abnormal total sleep score (T- score &gt;70) was at 3.5 %, and overall, 21.7 % of the children had an abnormal score on at least one SDSC factor. Among the children with sleep disturbances, we noted the following factors; use of an electronic device before bed, sleeping &lt;7 h at night, having unemployed parents and lack of regular parental interaction.</div></div><div><h3>Conclusion</h3><div>Better understanding of sleep disturbances in needed to address challenges associated with sleep among children in Uganda.</div></div>","PeriodicalId":74809,"journal":{"name":"Sleep epidemiology","volume":"5 ","pages":"Article 100104"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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