Seminars in neonatology : SN最新文献_第7页

Molecular determinants of sodium and water balance during early human development 早期人类发育过程中钠和水平衡的分子决定因素

Seminars in neonatology : SN Pub Date : 2003-08-01 DOI: 10.1016/S1084-2756(03)00042-3

Ulla Holtbäck, Anita C Aperia

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引用次数: 54

Clinical implications of postnatal alterations in body water distribution 出生后体内水分分布改变的临床意义

Seminars in neonatology : SN Pub Date : 2003-08-01 DOI: 10.1016/S1084-2756(03)00043-5

Neena Modi

引用次数: 37

Investigating the newborn kidney: update on imaging techniques 调查新生儿肾脏:影像学技术的最新进展

Seminars in neonatology : SN Pub Date : 2003-08-01 DOI: 10.1016/S1084-2756(03)00031-9

Isky Gordon , Michael Riccabona

引用次数: 30

Basic principles and practical steps in the management of fluid balance in the newborn 新生儿体液平衡管理的基本原则和实际步骤

Seminars in neonatology : SN Pub Date : 2003-08-01 DOI: 10.1016/S1084-2756(03)00032-0

Gary Hartnoll

引用次数: 36

Fetal renal impairment 胎儿肾损害

Seminars in neonatology : SN Pub Date : 2003-08-01 DOI: 10.1016/S1084-2756(03)00022-8

Tina Vanderheyden, Sailesh Kumar, Nicholas M Fisk

{"title":"Fetal renal impairment","authors":"Tina Vanderheyden, Sailesh Kumar, Nicholas M Fisk","doi":"10.1016/S1084-2756(03)00022-8","DOIUrl":"10.1016/S1084-2756(03)00022-8","url":null,"abstract":"<div><p>Renal function <em>in utero</em> deals chiefly with urine production rather than the excretion of metabolites, which are cleared by the placenta. Fetal renal impairment (FRI) in bilateral renal disease thus presents as oligohydramnios or anhydramnios; this can lead to lung hypoplasia and early neonatal death. As in the adult, FRI can be divided into prerenal, renal and postrenal causes. Causes of prerenal FRI include intrauterine growth restriction, unbalanced intertwin transfusion in monochorionic twins and maternal drug ingestion. Bilateral renal agenesis, multicystic dysplasia and both the autosomal dominant and recessive forms of polycystic kidney disease are examples of renal causes, whereas postrenal etiologies are usually caused by lower urinary tract obstruction (LUTO). When both kidneys are affected and there is severe mid-trimester oligohydramnios, the prognosis is poor. Although animal studies have shown that prolonged LUTO leads to lung hypoplasia and renal damage, and that decompression of the fetal kidney in early pregnancy restores fetal pulmonary and renal function, the value of fetal therapy such as vesico-amniotic shunting remains controversial, with a high procedure-related complication rate and a high incidence of end-stage renal failure in childhood. Fetal cystoscopic treatment of posterior urethral valves <em>in utero</em> may obviate some of these difficulties but remains an investigational procedure.</p></div>","PeriodicalId":74783,"journal":{"name":"Seminars in neonatology : SN","volume":"8 4","pages":"Pages 279-289"},"PeriodicalIF":0.0,"publicationDate":"2003-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1084-2756(03)00022-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24426925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 64

Volume expansion during neonatal intensive care: do we know what we are doing? 新生儿重症监护期间的体积扩张:我们知道我们在做什么吗?

Seminars in neonatology : SN Pub Date : 2003-08-01 DOI: 10.1016/S1084-2756(03)00021-6

Nick Evans

{"title":"Volume expansion during neonatal intensive care: do we know what we are doing?","authors":"Nick Evans","doi":"10.1016/S1084-2756(03)00021-6","DOIUrl":"10.1016/S1084-2756(03)00021-6","url":null,"abstract":"<div><p>Although volume expansion is liberally used in newborn intensive care, we know little about its effects on hemodynamics or outcomes. Given appropriately to a truly hypovolemic baby, it can be life-saving, but the clinical diagnosis of hypovolemia is probably very inaccurate. We know that volume expansion has less effect on blood pressure than dopamine, and although it seems to produce immediate increases in systemic blood flow, we do not know for how long these increases are sustained. There is evidence to show that the routine use of volume expansion in preterm babies has no effect on outcome, and there is little evidence to support its routine use during resuscitation or the treatment of metabolic acidosis. Whether crystalloids or colloids are preferable is also unclear in newborns. In situations of concern related to circulatory compromise, if possible, define the hemodynamics echocardiographically. Otherwise, if in doubt, some volume should be given, although it is probably unwise to keep expanding the volume if this is not improving physiologic (blood pressure and heart rate) or echocardiographic systemic blood flow parameters.</p></div>","PeriodicalId":74783,"journal":{"name":"Seminars in neonatology : SN","volume":"8 4","pages":"Pages 315-323"},"PeriodicalIF":0.0,"publicationDate":"2003-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1084-2756(03)00021-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24426929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Recent Advances in Neonatal Surgery 新生儿外科的最新进展

Seminars in neonatology : SN Pub Date : 2003-06-01 DOI: 10.1016/S1084-2756(03)00041-1

Agostino Pierro

引用次数: 4

Current therapy of infants with congenital diaphragmatic hernia 婴儿先天性膈疝的治疗现状

Seminars in neonatology : SN Pub Date : 2003-06-01 DOI: 10.1016/S1084-2756(03)00028-9

Cynthia D Downard, Jay M Wilson

{"title":"Current therapy of infants with congenital diaphragmatic hernia","authors":"Cynthia D Downard, Jay M Wilson","doi":"10.1016/S1084-2756(03)00028-9","DOIUrl":"10.1016/S1084-2756(03)00028-9","url":null,"abstract":"<div><p>Congenital diaphragmatic hernia (CDH) is a life-threatening anomaly with a significant mortality rate. Despite widespread prenatal diagnosis, few parameters have been well defined to aid in prediction of outcome of these infants. Antenatal maternal steroid administration and foetal surgery are not proven interventions. Postnatal treatment has changed over the last 10 years, with avoidance of hyperventilation and ventilator-induced lung injury resulting in improved survival. Therapies such as inhaled nitric oxide, exogenous surfactant administration and extracorporeal membrane oxygenation (ECMO) have undergone limited study, but show no clear benefit in this population. With improved outcome, principally due to avoidance of barotrauma, greater opportunity exists for long-term evaluation of survivors. To date, continuing problems with pulmonary function, nutrition and growth, effects of right ventricular hypertension and developmental issues have been identified. Through co-ordinated, multidisciplinary evaluation of CDH survivors, improved long-term outcome for these challenging patients can be attained.</p></div>","PeriodicalId":74783,"journal":{"name":"Seminars in neonatology : SN","volume":"8 3","pages":"Pages 215-221"},"PeriodicalIF":0.0,"publicationDate":"2003-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1084-2756(03)00028-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24425632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 50

Surgery of persistent hyperinsulinaemic hypoglycaemia 手术治疗持续性高胰岛素血症性低血糖

Seminars in neonatology : SN Pub Date : 2003-06-01 DOI: 10.1016/S1084-2756(03)00027-7

Keith J Lindley , Lewis Spitz

引用次数: 5

Foetal surgery for spina bifida 脊柱裂的胎儿手术

Seminars in neonatology : SN Pub Date : 2003-06-01 DOI: 10.1016/S1084-2756(03)00030-7

Danielle S. Walsh , N.Scott Adzick

引用次数: 0