Alergologia Polska - Polish Journal of Allergology最新文献_第5页

Skin manifestations associated with COVID-19 与COVID-19相关的皮肤表现

IF 0.2

Alergologia Polska - Polish Journal of Allergology Pub Date : 2022-01-01 DOI: 10.5114/pja.2022.119226

Aleksandra Tatka, R. Pawliczak

{"title":"Skin manifestations associated with COVID-19","authors":"Aleksandra Tatka, R. Pawliczak","doi":"10.5114/pja.2022.119226","DOIUrl":"https://doi.org/10.5114/pja.2022.119226","url":null,"abstract":"The COVID-19 pandemic, announced by the World Health Organization in March 2020, remains the subject of research and analysis by scientists working in various branches of medicine. Coronavirus-associated disease is most commonly associated with characteristic pulmonary symptoms. Cutaneous manifestations in the course of SARS-CoV-2 as extrapulmonary manifestations of the disease represent a major diagnostic and therapeutic challenge. Diverse clinical aspects of dermatological manifestations hinder correct differentiation and diagnosis. The prevalence of skin lesions associated with COVID-19 is estimated to be over 6% of affected patients. Several clinical patterns strongly associated with COVID-19 have been described, such as pseudo-ulcerative, maculopapular, urticarial, vesicular, and vascular lesions. Cutaneous dermatitis may coexist with mucocutaneous manifestations involving the oral cavity and ocular surface. Cutaneous manifes tations of COVID-19 are classified in the literature according to their clinical features, possible mechanisms of pathogenesis, and prevalence. The pathogenetic mechanism, diagnostic criteria, prognostic significance of these lesions are still being discussed. This review summarizes the current knowledge about the cutaneous manifestations associated with COVID-19. The period of symptom occurrence, severity, need for specific treatment, and prognosis depends on the clinical presentation. Physicians with knowledge of the cutaneous manifestations of COVID-19 can quickly differentiate and then make an accurate diagnosis and implement appropriate treatment.","PeriodicalId":7469,"journal":{"name":"Alergologia Polska - Polish Journal of Allergology","volume":"18 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70480986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Ocular complications of atopic dermatitis in children and adolescents 儿童和青少年特应性皮炎的眼部并发症

IF 0.2

Alergologia Polska - Polish Journal of Allergology Pub Date : 2022-01-01 DOI: 10.5114/pja.2022.116288

Murat Özer, M. Aksoy, M. Şimşek

{"title":"Ocular complications of atopic dermatitis in children and adolescents","authors":"Murat Özer, M. Aksoy, M. Şimşek","doi":"10.5114/pja.2022.116288","DOIUrl":"https://doi.org/10.5114/pja.2022.116288","url":null,"abstract":"Introduction: Atopic dermatitis (AD) is a prevalent inflammatory skin disease, often starts in childhood and tends to flare up periodically. Patients with AD may be at higher risk of several ocular complications. Aim: To evaluate the relationship of frequency, type, and severity of ophthalmic complications in children and adolescents with AD. Material and methods: This study included 64 patients between ages 0 and 18 who were diagnosed with AD between January 1, 2020 and June 30, 2020. Hanifin and Rajka criteria were used for diagnosis of AD, and the SCORAD score was used to assess severity. Data were statistically analyzed using IBM SPSS 22. Results: A total of 64 patients diagnosed with AD with a mean age of 40.4 (4–198) months were included in the study. Periocular AD findings were detected in 12 (21%) cases and ocular findings in 15 (23%) cases. AD lesions were observed in the facial region of 35 patients. The mean age of the patients was 99.6 (52–192) months in the group with ocular findings and 22.2 (4–198) months in the group without ocular findings; there was a statistically significant difference between the two groups ( p < 0.001). While ophthalmic involvement correlated with periocular involvement ( r = 0.585, p < 0.001) and facial involvement ( r = 0.281, p = 0.024), there was no correlation between SCORAD and ocular involvement ( r pb = 0.129, p = 0.31). Conclusions: It was observed that the risk of eye involvement was increased in girls, older children, and in cases with facial and periorbital involvement. This study demonstrated that severe ophthalmic complications are rare in children with mild AD, but the risk of ocular involvement increases with age and in those with facial and periocular involvement.","PeriodicalId":7469,"journal":{"name":"Alergologia Polska - Polish Journal of Allergology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70480459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Usefulness of DAO biomarker in difficult allergy. Consideration based on own typical cases DAO生物标志物在难治性过敏中的应用。基于自身典型案例的考虑

IF 0.2

Alergologia Polska - Polish Journal of Allergology Pub Date : 2022-01-01 DOI: 10.5114/pja.2022.122003

K. Buczyłko

引用次数: 0

Diagnostics of peanut allergy – part II 花生过敏的诊断-第二部分

IF 0.2

Alergologia Polska - Polish Journal of Allergology Pub Date : 2022-01-01 DOI: 10.5114/pja.2022.119229

Julia Gawryjołek, A. Krogulska

引用次数: 0

Autonomic nervous system dysfunction and the effectof vitamin D level in vasomotor rhinitis patients 血管舒缩性鼻炎患者自主神经系统功能障碍及维生素D水平的影响

IF 0.2

Alergologia Polska - Polish Journal of Allergology Pub Date : 2022-01-01 DOI: 10.5114/pja.2022.122007

Saltuk Buğra Kaya, Mehmet Erdem Çakmak, E. Damadoğlu, G. Karakaya, A. Fuat Kalyoncu

引用次数: 0

The concept of a false-positive (result) in the context of COVID-19 diagnostics and medical recommendations 在COVID-19诊断和医疗建议的背景下假阳性(结果)的概念

IF 0.2

Alergologia Polska - Polish Journal of Allergology Pub Date : 2022-01-01 DOI: 10.5114/pja.2022.116289

E. Stoczyńska-Fidelus, P. Rieske

{"title":"The concept of a false-positive (result) in the context of COVID-19 diagnostics and medical recommendations","authors":"E. Stoczyńska-Fidelus, P. Rieske","doi":"10.5114/pja.2022.116289","DOIUrl":"https://doi.org/10.5114/pja.2022.116289","url":null,"abstract":"COVID-19 is an example of a big challenge for diagnostics. In the case of many diseases and syndromes, there is a possibility to repeat the tests, and the time allocated for diagnosis is counted even in weeks, not in hours, as in COVID-19. The situation related to COVID-19, therefore leads to a large number of tensions, both among diagnostic physicians and patients. Especially that in this case, based on a positive result, the decision is being made not only about the choice of a possible therapy, but also about quarantine. This article refers to the predictive value of tests used in the diagnosis of COVID-19 (mainly RT-PCR), focusing on the concept of a false positive result. The article demonstrates that this is a relative term, depending on the question posed, the purpose of the diagnosis (selection of therapy, quarantine decision, disease detection), or even the variant of the SARS-CoV-2 virus. Effective vaccination against COVID-19, the increasing percentage of convalescent patients, and the emergence of the SARS-CoV-2 omicron variant minimalize all these problems. However, shifting away from widely used screening tests, should not cause abandoning COVID-19 testing completely. Part of the population may still die from the disease and effective targeted therapy already exists. In order to personalize this therapy, a test such as RT-PCR must be used.","PeriodicalId":7469,"journal":{"name":"Alergologia Polska - Polish Journal of Allergology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70480647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current allergen immunotherapy market situation – September 2022 过敏原免疫治疗市场现状- 2022年9月

IF 0.2

Alergologia Polska - Polish Journal of Allergology Pub Date : 2022-01-01 DOI: 10.5114/pja.2022.122004

Adam Górka, R. Pawliczak

引用次数: 0

Bronchial asthma and its triggers: a case study in eastern Slovakia 支气管哮喘及其诱因:斯洛伐克东部的一个案例研究

IF 0.2

Alergologia Polska - Polish Journal of Allergology Pub Date : 2022-01-01 DOI: 10.5114/pja.2022.119234

Gabriela Harvanová, S. Duranková, A. Csanády, Ľubov Rosoľanková, M. Majherová

引用次数: 0

The impact of commercially available air purifiers on bronchial asthma and allergy symptoms 市售空气净化器对支气管哮喘和过敏症状的影响

IF 0.2

Alergologia Polska - Polish Journal of Allergology Pub Date : 2022-01-01 DOI: 10.5114/pja.2022.114396

Joanna Wieczfinska, R. Pawliczak

引用次数: 1

Cigarette smoking and oxidative stress 吸烟和氧化应激

IF 0.2

Alergologia Polska - Polish Journal of Allergology Pub Date : 2022-01-01 DOI: 10.5114/pja.2022.116285

Artur Nowak, R. Pawliczak

{"title":"Cigarette smoking and oxidative stress","authors":"Artur Nowak, R. Pawliczak","doi":"10.5114/pja.2022.116285","DOIUrl":"https://doi.org/10.5114/pja.2022.116285","url":null,"abstract":"Cigarette smoke is a complex mixture of more than 6000 chemical compounds, including high concentrations of free radicals and other oxidants. Cigarette smoke is also a source of free radicals. It is known that free radicals and lipid peroxidation have roles in pathogenesis of cardiovascular and pulmonary disease such as coronary artery disease and chronic obstructive pulmonary disease. Cigarette smoking is the major cause of preventable morbidity and mortality in Poland and constitutes a major risk factor for atherosclerotic vascular disease. It is believed that smoking causes increased oxidative stress because of several mechanisms, including direct damage by radicals. Moreover, numerous studies have indicated greater levels of oxidative stress in cigarette smokers, which is most likely attributable to the high concentration of reactive oxygen species in cigarette smoke. Homeostasis of an organism and its proper functioning are determined by the oxidative-antioxidant balance. Its disorder is most often associated with overproduction of reactive oxygen species that cause oxidative stress. It is a condition where an imbalance exists between the production of reactive oxygen species and the body’s ability to neutralize these intermediates, resulting in cellular damage. Cigarette smoke is known to be both a source and an inducer of cellular oxidative stress, which is a factor in many smoking-related diseases, and this oxidative stress initiates a variety of pathological processes which contribute to disease development. According to the World Health Organization, active smoking is one of the leading causes of death among people in the world through diseases caused by the toxic components of tobacco smoke.","PeriodicalId":7469,"journal":{"name":"Alergologia Polska - Polish Journal of Allergology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70480415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1