Recent advances in food, nutrition & agriculture最新文献

{"title":"Evaluation of Hordenine's Therapeutic Potential in Alzheimer's Disease-Induced Cognitive and Oxidative Impairments.","authors":"Mohit Agarwal, Manmohan Singhal, Parakh Basist, Neha Tamta, Shivendra Kumar, Sunam Saha","doi":"10.2174/012772574X389943250908070348","DOIUrl":"https://doi.org/10.2174/012772574X389943250908070348","url":null,"abstract":"<p><strong>Introduction: </strong>This research aimed to investigate the potential of Hordenine (HR) against Alzheimer's Disease (AD) induced by Streptozotocin (STZ) in Wistar rats by evaluating its impact on cognitive function, oxidative stress, inflammatory cytokines, and neuroprotective biomarkers in comparison to donepezil.</p><p><strong>Methods: </strong>The study involved five groups of Wistar rats: a control group, a group with STZinduced AD, and three treatment groups receiving varying doses of HR (50 mg/kg and 75 mg/kg) and donepezil (5 mg/kg). Over 28 days, the animals underwent various behavioural tests to assess cognitive function, along with biochemical analyses to measure A+cetylcholinesterase (AChE) activity, oxidative stress markers, inflammatory cytokines (IL-1β, TNF-α), and nuclear factor kappa B (NF-κB) levels, and histological examination. Additionally, molecular docking studies were performed to assess the interaction of HR with AChE.</p><p><strong>Results: </strong>STZ administration caused significant cognitive decline, oxidative stress, and elevated inflammatory markers. HR supplementation, particularly at 75 mg/kg, significantly improved cognition, reduced oxidative stress, and decreased pro-inflammatory cytokines (IL-1β, TNF-α), as well as NF-κB levels, while increasing Brain-Derived Neurotrophic Factor (BDNF) expression. Molecular docking studies revealed strong binding of HR to AChE, suggesting potential inhibitory effects.</p><p><strong>Discussion: </strong>Hordenine demonstrated promising neuroprotective effects against STZ-induced neurotoxicity by improving cognition and reducing oxidative stress and inflammation, suggesting HR's potential as an adjunct therapy for Alzheimer's disease, offering a protective mechanism that may complement existing treatments like donepezil.</p><p><strong>Conclusion: </strong>The research shows that the medicinal plant HR exhibits neuroprotective potential against AD induced by STZ. Further research involving clinical trials is warranted to fully establish the efficacy and safety of HR in the treatment of AD.</p>","PeriodicalId":74644,"journal":{"name":"Recent advances in food, nutrition & agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Glucosinolates Beyond Plant Defense: Harnessing their Therapeutic Potential from Gut Health to Cancer Prevention.","authors":"Debangana Chakraborty, Madhura Das, Aniket Das, Megha Roy, Sanjana Gupta, Jutishna Bora, Sumira Malik, Sarmistha Ray","doi":"10.2174/012772574X403563250910193929","DOIUrl":"https://doi.org/10.2174/012772574X403563250910193929","url":null,"abstract":"<p><p>Glucosinolates are plant-derived secondary metabolites with significant antimicrobial, anticancer, and gut microbiota-modulating properties. Their hydrolysis products, such as isothiocyanates, contribute to planting defense mechanisms and exhibit potential therapeutic applications. This study aimed to explore the metabolism, biosynthesis, antimicrobial activity, and therapeutic potential of glucosinolates, emphasizing their role in human health. This literature review focuses on the analysis of existing studies on glucosinolate biosynthesis, metabolism, and biological activity. Research data have been gathered from scientific databases, focusing on in vivo and in vitro studies that have examined the antimicrobial, anticancer, and gut microbiota- modulating effects of glucosinolates and their derivatives. Findings suggest that glucosinolates play a crucial role in human health by exerting antimicrobial properties against various bacterial strains, modulating gut microbiota composition, and reducing cancer risk through their bioactive breakdown products. Their biosynthetic pathway involves key enzymatic reactions, and variations in these processes affect their biological efficacy. However, bacterial resistance to isothiocyanates poses a challenge that requires further investigation. Glucosinolates and their hydrolysis products offer promising therapeutic applications, particularly in disease prevention and gut health modulation. Future research should focus on optimizing their bioavailability and understanding resistance mechanisms to enhance their efficacy in clinical applications.</p>","PeriodicalId":74644,"journal":{"name":"Recent advances in food, nutrition & agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green Synthesis of Nanoparticles: Sustainable Solutions for Multisectoral Applications.","authors":"Bharat Veer, Shatrudhan Prajapati, Ajay Pal Singh, Shikha Yadav","doi":"10.2174/012772574X387119250907090028","DOIUrl":"https://doi.org/10.2174/012772574X387119250907090028","url":null,"abstract":"<p><p>Green synthesis has emerged as a cornerstone for advancing eco-friendly nanotechnology by utilizing plant extracts, microorganisms, and natural compounds as reducing and stabilizing agents. This sustainable approach mitigates the environmental and health hazards associated with conventional chemical and physical synthesis methods. Green-synthesized nanoparticles (NPs) exhibit remarkable potential across diverse sectors, including agriculture, pharmaceuticals, environmental remediation, and materials science. By leveraging renewable resources, this process minimizes energy consumption, toxic byproducts, and waste generation. Recent studies highlight the use of plant metabolites, fungi, and bacteria for the synthesis of metallic nanoparticles such as silver, gold, and zinc oxide, demonstrating enhanced biocompatibility and reduced toxicity. Characterization techniques such as UV-Vis spectroscopy, X-ray diffraction, and electron microscopy confirm the structural integrity and functional properties of these nanoparticles. In agriculture, green NPs act as efficient nanofertilizers, pesticide carriers, and biosensors, enhancing crop yield and reducing chemical dependency. In the medical field, they play pivotal roles in drug delivery, imaging, and antimicrobial therapies. Furthermore, green nanoparticles contribute to wastewater treatment, pollutant adsorption, and air purification, addressing critical environmental challenges. This review underscores the transformative potential of green synthesis in promoting sustainable industrial practices, fostering innovation, and aligning with the global agenda for environmental responsibility. By integrating green nanotechnology into mainstream production, industries can achieve a balance between technological advancement and ecological preservation, paving the way for a greener, healthier future.</p>","PeriodicalId":74644,"journal":{"name":"Recent advances in food, nutrition & agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary Fiber: A Comprehensive Review of Its Sources, Health Benefits, and Mechanisms Driving Nutraceutical Effects.","authors":"Bisma Jan, Parakh Basist, Shradanjli Mohapatra, Muhammad Umar Khan, Bharti Choudhary","doi":"10.2174/012772574X378014250727175222","DOIUrl":"https://doi.org/10.2174/012772574X378014250727175222","url":null,"abstract":"<p><p>India, the second-largest producer of fruits and vegetables globally, generates significant quantities of agricultural by-products such as bran, husk, and seeds due to its rapidly expanding food processing sector. These by-products offer valuable opportunities for the extraction of dietary fiber and bioactive components, which can be incorporated into functional foods and nutraceutical products to address growing health concerns. Dietary fiber, an indigestible component of plant-based foods, can be classified into soluble and insoluble forms. Soluble fibers, derived from sources such as oat bran, barley, lentils, and certain fruits and vegetables, are rich in pectin, beta-glucans, and inulin. Insoluble fibers, found in wheat bran, cereal grains, and vegetables, primarily consist of cellulose and hemicellulose. This review explores the potential of dietary fiber in disease management, its diverse sources, and its application in functional and nutraceutical products. Regular intake of dietary fiber is associated with a reduced risk of coronary heart disease, stroke, hypertension, diabetes, obesity, and various gastrointestinal disorders. Soluble fiber, in particular, improves glycemic control and insulin sensitivity, while fiber supplementation aids in weight management among obese individuals. Additionally, increased fiber consumption is linked to lower blood pressure and serum cholesterol levels. Dietary fiber also alleviates gastrointestinal conditions such as gastroesophageal reflux disease, constipation, and hemorrhoids, while prebiotic fibers enhance immune function. Despite its proven benefits, consumer awareness regarding dietary fiber remains insufficient. Enhancing communication and education on the importance of fiber-rich foods and supplements is essential to promote their widespread consumption and leverage their health benefits effectively.</p>","PeriodicalId":74644,"journal":{"name":"Recent advances in food, nutrition & agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probiotification of a Tropical Juice Blend using Lactobacillus bulgaricus and Lactobacillus plantarum: A Preliminary Study.","authors":"Carmencita Duberry, Rohanie Maharaj, Dimple Singh-Ackbarali, Vishal Ganessingh","doi":"10.2174/012772574X394951250611073352","DOIUrl":"https://doi.org/10.2174/012772574X394951250611073352","url":null,"abstract":"<p><strong>Background: </strong>Probiotics are beneficial microorganisms that support host health when consumed in adequate amounts. While fruit juices are promising non-dairy carriers for probiotics, consumer acceptance remains a challenge.</p><p><strong>Objective: </strong>This study aimed to develop a viable, palatable probiotic beverage using a blend of fresh fruits and a vegetable, providing an easy-to-consume source of nutrients.</p><p><strong>Methods: </strong>Probiotification of pasteurized and untreated tropical juice blends (carrot, orange, pineapple, and passion fruit juices) was achieved through fermentation using two strains of Lactic Acid Bacteria (LAB) (Lactobacillus bulgaricus and Lactobacillus plantarum). Fermentation was carried out at 37℃ for 48 h in a microaerophilic environment. Shelf-life studies were conducted at 35℃, 23°C, and 4°C, over 10, 10, and 21 days for untreated and pasteurized juices, respectively. Parameters assessed included the probiotic viability, presence of spoilage coliforms, pH, titratable acidity, ascorbic acid, total soluble solids content, and colour.</p><p><strong>Results: </strong>Both LAB strains reduced the juice pH within 48 hours of fermentation. The viability of probiotic cells was maintained at 4.08 × 1010 CFU mL-1 with no spoilage coliforms detected during refrigerated storage. No significant differences were observed in physicochemical properties (pH, TSS, TA, or colour) between the pasteurized and unpasteurized probiotic juice blends after 48 hours at 37°C. Sensory analysis indicated higher consumer acceptance of the fermented juice blends over a commercial probiotic beverage in terms of appearance, fruity flavour, sweetness, and mouthfeel.</p><p><strong>Conclusion: </strong>Probiotic juice blends could offer a potential option for lactose-intolerant and vegan consumers, providing a nutritious, palatable, and viable alternative to commercial dairy probiotic beverages.</p>","PeriodicalId":74644,"journal":{"name":"Recent advances in food, nutrition & agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antidepressant Efficacy of Nutraceutical Gummies: Formulation of With-ania Somnifera and Valeriana officinalis Evaluated in Force Swim Test Model.","authors":"Parvinder Mann, Uddeshya Sharma, Gurvirender Singh, Geeta Jangra","doi":"10.2174/012772574X375447250528171314","DOIUrl":"https://doi.org/10.2174/012772574X375447250528171314","url":null,"abstract":"<p><strong>Objective: </strong>This investigation aims to elucidate the potential of nutraceuticals as a therapeutic modality for depression by enhancing the solubility and bioavailability of Withania somnifera (Ashwagandha) using specific solid dispersion techniques.</p><p><strong>Methodology: </strong>Solid Withania somnifera and Valeriana officinalis dispersions were prepared via hot melt extrusion and solvent evaporation. These processes increased the aqueous solubility of Ashwagandha by 3.2-fold (from 44.2 μg/mL to 142 μg/mL). An optimal 1:2 drug-to-hydrotropic agent ratio was selected based on comprehensive DSC, PXRD, and FTIR characterisation, indicating partial amorphisation and effective molecular interactions with β-cyclodextrin. The resulting solid dispersion was incorporated into nutraceutical gummies, formulated using type B gelatin, high-methoxyl pectin, and food-grade guar gum via a standardized molding process. The antidepressant efficacy of these gummies was assessed in murine models using the Forced Swim Test, with quantitative evaluation of changes in immobility time and climbing behavior.</p><p><strong>Results: </strong>The solid dispersion methodology significantly enhanced Ashwagandha's solubility (3.2-fold increase). In the Forced Swim Test, animals treated with the gummy formulation exhibited a 40% reduction in immobility time and a 35% increase in climbing activity compared to controls, indicating a robust antidepressant effect.</p><p><strong>Conclusions: </strong>This study presents a novel nutraceutical approach to managing depression. By optimizing the solubility and bioavailability of key herbal constituents through advanced solid dispersion techniques, the gummy formulation offers a promising alternative or adjunctive treatment for depressive disorders.</p>","PeriodicalId":74644,"journal":{"name":"Recent advances in food, nutrition & agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutraceuticals in Depression Management: Current Evidence and Perspectives.","authors":"Parvinder Mann, Geeta Jangra, Komal Saini, Smita Narwal, Ashwani K Dhingra, Gurvirender Singh","doi":"10.2174/012772574X361750250323111150","DOIUrl":"https://doi.org/10.2174/012772574X361750250323111150","url":null,"abstract":"<p><strong>Background: </strong>Depression is a common psychiatric disorder characterized by feel-ings of sadness, diminished interest in activities, and disruptions in sleep patterns. Pharmaco-therapy, which often involves the use of antidepressant medicines, are method for managing depression. There are potential negative effects linked to the utilization of these medicines, even though many people have found them to be beneficial.</p><p><strong>Objective: </strong>Traditional pharmacological therapies for depression can have a variety of ad-verse effects or drawbacks. To overcome these constraints, nutraceuticals have come into the picture of interest. Nutraceuticals, which are naturally derived compounds with potential therapeutic benefits, have attracted interest as an innovative approach to treating depression. In this review, the efficacy of nutraceuticals in depression will be discussed.</p><p><strong>Methods: </strong>To find pertinent research on nutraceuticals in the treatment of depression, a thor-ough literature analysis was enacted. Studies investigating the significance of nutraceuticals on depression signs, patent perspectives, and clinical studies were included.</p><p><strong>Results: </strong>The findings suggest that several nutraceuticals, including omega-3 fatty acids, di-etary fibers, and phytochemicals, including Ashwagandha and valerian, exhibit antidepres-sant effects. These compounds have shown promising results in improving depressive symp-toms, enhancing neuroplasticity and neurogenesis, and regulating neurotransmitter imbal-ances.</p><p><strong>Conclusion: </strong>Nutraceuticals offer a novel approach to depression, providing potential bene-fits in alleviating depressive symptoms. Correlative review suggests that increasing intake of these substances could be an alternate method for delaying the early symptoms and course of depression. Supplementation with dietary fibers, Omega-3 fatty acids, and phytochemi-cals can be utilized as a complementary strategy for anti-depressant therapy.</p>","PeriodicalId":74644,"journal":{"name":"Recent advances in food, nutrition & agriculture","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Production and Chemical Characterization of Silage from Saccharine Sorghum Fertirrigated with Sugarcane Vinasse.","authors":"Arlindo Fabrício Correia, Antonio Cesar Godoy, Jarred H Oxford, Marcos Paiva Scardua, Paulo Sérgio Rabello de Oliveira, Nelson Fukumoto, Armin Feiden","doi":"10.2174/012772574X297369240506044541","DOIUrl":"10.2174/012772574X297369240506044541","url":null,"abstract":"<p><strong>Background: </strong>Distillery vinasse is one of the promising bio-fertilizers, as it contains significant amounts of essential chemical elements, allied with sorghum that is widely used in the diet of ruminant animals and has been considered as an alternative to the production of other cereals or forages. This study aimed to evaluate saccharin sorghum silage from fertilization with vinasse.</p><p><strong>Methods: </strong>The research was conducted using the BRS-511, CR-1339, and CR-1342 genotypes. The silage was held for 170 days after sowing, with experimental design in blocks with triple factorial (genotypes x fertilization x inoculation) totaling 54 installments. At 95 days, the silos were opened for sample collection and analysis bromatological analysis.</p><p><strong>Results: </strong>The results indicate the primary source of variation was genotype, characterizing them with different potentials in productivity and better results for BRS-511, CR-1339, and CR-1342. The bromatological results indicate good quality for CR-1339 and CR-1342 hybrids, however, better digestability for BRS-511. There was no observable difference between the factors of fertilization. The inoculation additive assists in the reduction of lignin appears to be high. PCA analysis showed differences between cultivars (BRS-511, CR-1339, and CR-1342) and fertilization. However, the PCAs showed the genotypes show similar results with conventional fertilization and sugarcane vinasse.</p><p><strong>Conclusion: </strong>The study reflected the possibility of producing sweet sorghum silage with soil sugarcane vinasse fertilization as fertilizer.</p>","PeriodicalId":74644,"journal":{"name":"Recent advances in food, nutrition & agriculture","volume":" ","pages":"206-214"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141157752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Growth Promotion and <i>In Vitro</i> Seed Germination of <i>Lycium barbarum</i> L. (Red Goji) Using Different Types of Cytokinins.","authors":"Nurul Izzati Osman, Ainun Fazdilah Azmi","doi":"10.2174/012772574X313421240902052600","DOIUrl":"10.2174/012772574X313421240902052600","url":null,"abstract":"<p><strong>Introduction: </strong>Lycium barbarum L., commonly known as red goji berry, is a widely recognized plant-based medicinal herb with nutritional and therapeutic properties. In this study, the effects of various cytokinins on the germination of L. barbarum seeds and the growth of seedlings were investigated under in vitro conditions.</p><p><strong>Methods: </strong>The berries were first surface sterilized and dissected, and the seeds were then cultured on Murashige and Skoog (MS) medium supplemented with different concentrations (0.5, 1.0, and 1.5 mg/L) of 6-benzylaminopurine (BAP), thidiazuron (TDZ), and kinetin (KIN) for 10 weeks at 25±2ºC with a photoperiod of 16 hours and a light intensity of 1000 lux. Upon observation after 10 weeks of culture, all cytokinin-treated cultures produced 100% seed germination as early as 7 days. KIN at 0.5 mg/L produced plantlets with the greatest height (8.40 ± 0.97 cm) with extensive rooting and the greatest total chlorophyll production. Besides, KIN at 1.5 mg/L resulted in the highest number of leaves per plantlet (6.90 ± 0.72), while 1.0 mg/L of TDZ led to the greatest biomass, i.e., fresh weight (FW) of 0.328 ± 0.05 gram and dry weight (DW) of 0.023 ± 0.003 gram.</p><p><strong>Results: </strong>All cytokinins used in this experiment (BAP, TDZ, and KIN) promoted different in vitro growth promotion responses in L. barbarum. The effects of different types and concentrations of cytokinin on the height of plantlets, number of leaves per plantlet, fresh and dry weight, the extent of rooting, and the chlorophyll content were demonstrated to be statistically significant.</p><p><strong>Conclusion: </strong>This study provides valuable insights into optimizing in vitro cultivation techniques for goji berry propagation, which could contribute to developing superior cultivars and increased production of this superfruit in the future. For future perspectives, extended research in elucidating the underlying mechanism associated with cytokinin supplementation is imperative in understanding the roles of cytokinins and optimizing their effects on plant growth promotion.</p>","PeriodicalId":74644,"journal":{"name":"Recent advances in food, nutrition & agriculture","volume":" ","pages":"334-340"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Ultra-processed Foods on Food Sustainability: Exposure Assessment and Health Implications.","authors":"Muskan Chadha, Ratnakar Shukla, Rohit Kumar Tiwari, Dharmendra Kumar Dubey, Karuna Singh","doi":"10.2174/012772574X327683240910063234","DOIUrl":"10.2174/012772574X327683240910063234","url":null,"abstract":"<p><p>Excessive consumption of ultra-processed foods (UPF) is a global health concern associated with an increased incidence of non-communicable diseases. UPF are characterized by their extensive industrial processing and high content of additives, preservatives, chemicals, and artificial ingredients that are used to mask defects or inferior ingredients of end food products, presenting a multifaceted challenge to contemporary society. Exposure assessment showed that almost 50% to 30% of the energy consumption per day comes from UPF. The more processed a food is, the less likely it is to be healthy and nutritious. UPF affect human health by increasing the risk of obesity, heart disease, cancer, depression, diabetes, etc., as these foods are typically made up of a large number of preservatives, high content of fats, sodium, and sugars, and low contents of protein, fiber, and potassium. The ingredients required for the production of UPF are commonly derived from intensive monoculture and livestock of raw foods. This, in turn, exerts imminent effects on agriculture, biodiversity, and the global food system by altering the bioavailability of nutrients within agricultural soil, thereby increasing the dependency on fertilizers and insecticides. Recent studies have shown that over-consumption of UPF has an effect on culinary traditions, loss of biodiversity, human well-being, and food system sustainability. Therefore, for better food system sustainability, the consumption of UPF should be reduced, and we should move toward minimal processing technologies, preferably for seasonal and organic local products. Based on available data, there is an urgent need to implement policies and regulations for the agro-food industry to include nutritional and environmental criteria. This review explains the different dimensions of UPF in relation to health, nutrition, environment, current challenges, future innovations, and wider sustainability concerns.</p>","PeriodicalId":74644,"journal":{"name":"Recent advances in food, nutrition & agriculture","volume":" ","pages":"299-314"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}