Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society最新文献

{"title":"A case of severe ARIA with multiple infarctions and extensive microbleeds following lecanemab administration.","authors":"Akiko Yamazaki, Tetsuro Sekine, Shiro Takahashi, Koji Sohara, Masanori Sakamaki, Takehiko Nagao, Kazumi Kimura, Masahiro Mishina","doi":"10.1111/psyg.13231","DOIUrl":"10.1111/psyg.13231","url":null,"abstract":"","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":"25 1","pages":"e13231"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11655173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low frequency-repetitive transcranial magnetic stimulation combined with Xingnao Kaiqiao acupuncture improves post-stroke cognitive impairment and has better clinical efficacy.","authors":"Xiao Xun, Yanhong Liu, Weimin Pan, Lang Tang, Changling Hu, Hua Ouyang, Qiu Liu, Hongliang Zeng, Dan Li","doi":"10.1111/psyg.13199","DOIUrl":"10.1111/psyg.13199","url":null,"abstract":"<p><strong>Background: </strong>Enhancing post-stroke cognitive impairment (PSCI) is a key aspect of prognosis for stroke patients. Low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) is currently a widely utilised method for treating PSCI. With the increasing promotion of traditional Chinese medicine, Xingnao Kaiqiao (XNKQ) acupuncture has been progressively incorporated into clinical treatment. This paper observes the effect of LF-rTMS with XNKQ acupuncture on patients with PSCI.</p><p><strong>Methods: </strong>Totally, 192 patients with PSCI were consecutively recruited and treated either with LF-rTMS and XNKQ acupuncture (observation group) or LF-rTMS only (control group) for 4 weeks. The pre- and post-treatment Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) scores, P300 latency and amplitude, inflammatory factor levels were compared and clinical efficacy was assessed.</p><p><strong>Results: </strong>Both groups exhibited increased MMSE/MoCA scores, and P300 amplitude, and shortened P300 latency, and the observation group had higher scores and P300 amplitude, and shorter P300 latency than the control group. Both groups displayed decreased inflammatory factor levels (Tumour necrosis factor-α, interleukin (IL)-6, IL-10, IL-1β) after treatment, which were lower in the observation group than the control group. Inflammatory factor levels in PSCI patients were negatively interrelated with MMSE, MoCA score and P300 amplitude, and positively with P300 latency. The observation group showed an increased number of patients showing cured and significantly effective results, a decreased number of patients showing effective and invalid results, and an observably elevated total effective rate.</p><p><strong>Conclusion: </strong>LF-rTMS with XNKQ acupuncture can improve cognitive function and reduce inflammatory immune response, and has better clinical efficacy in PSCI patients.</p>","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":" ","pages":"e13199"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of art therapy on cognitive status and psychological well-being in elderly people in institutional care.","authors":"Özge Demirel, Oya Sevcan Orak","doi":"10.1111/psyg.13246","DOIUrl":"10.1111/psyg.13246","url":null,"abstract":"<p><strong>Background: </strong>Cognitive decline seen in old age manifests itself as a decrease in reasoning ability that is not related to intelligence. This situation, together with many other problems, can affect the psychological well-being of the elderly. Especially the elderly living in institutional care constitute a special group that needs to be protected. It is important that the psychotherapy interventions to be carried out with this group are determined according to the characteristics of the group. The aim of this study is to determine the effect of art therapy on cognitive status and psychological well-being in the elderly living in institutional care.</p><p><strong>Methods: </strong>This single-blind randomised controlled study was conducted with 42 elderly individuals living in three nursing homes in Türkiye. In the study, the sample group was assigned to the experimental (n = 21) and control (n = 21) groups by simple randomisation. Art therapy intervention was applied to the elderly individuals in the experimental group, and no special intervention was applied to the control group. The sociodemographic information form, standardised mini mental test (MMT) and Psychological Well-being Scale for the Elderly (PWBS) were used as data collection tools in the study.</p><p><strong>Results: </strong>It was found that there was a statistically significant difference between the pre-test and post-test total scores of the PWBS and MMT in favour of the post-test (P < 0.001). In the study, the effect of the art therapy intervention applied to the elderly individuals in the experimental group was evaluated and it was determined that the difference between the PWBS ( <math> <semantics> <mrow><msup><mi>η</mi> <mn>2</mn></msup> </mrow> <annotation>$$ {eta}^2 $$</annotation></semantics> </math>  = 0.75) and MMT ( <math> <semantics> <mrow><msup><mi>η</mi> <mn>2</mn></msup> </mrow> <annotation>$$ {eta}^2 $$</annotation></semantics> </math>  = 0.52) scores had a medium effect level.</p><p><strong>Conclusions: </strong>The results showed that art therapy has a positive effect on the psychological well-being and cognitive status of the elderly in institutional care and can be used as a moderate developmental intervention.</p>","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":"25 1","pages":"e13246"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive frailty as a predictor of hospitalisation among older adults: a systematic review and meta-analysis.","authors":"Min Cheng, Qin Liu, Miao Li, Mei He","doi":"10.1111/psyg.13213","DOIUrl":"10.1111/psyg.13213","url":null,"abstract":"<p><p>To examine whether cognitive frailty serves as a predictor of hospitalisation in older adults. PubMed, Web of Science, Embase, Scopus and Cochrane Library databases were systematically searched from inception to February 6, 2024. The reviewers independently selected studies, extracted data and evaluated the quality of studies. Stata 15.1 Software was used to perform the meta-analysis. A total of 13 articles were included in this study, including 34 230 participants. The results suggested that cognitive frailty was associated with hospitalisation in older adults (odds ratio (OR) = 1.79, 95% CI: 1.33-2.42, P < 0.001). The risk of hospitalisation for patients with cognitive frailty was 1.76 times higher than that for patients without cognitive frailty (relative risk = 1.76, 95% CI: 1.48-2.08, P < 0.001). According to different models of cognitive frailty, the results of subgroup analysis showed that the frail + cognitive impairment group had the highest risk of hospitalisation (OR = 2.22, 95% CI: 1.51-3.26, P < 0.001). Subgroup analysis based on study design showed that the incidence of hospitalisation was lowest in the cohort study group (OR = 1.51, 95% CI: 1.14-2.00, P = 0.004). This study suggested that cognitive frailty was an important predictor of hospitalisation in older adults. Future studies are needed to investigate the impact of cognitive frailty on hospitalisation in older adults, as this may help reduce hospitalisation rates and improve patients' quality of life.</p>","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":" ","pages":"e13213"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life and post-traumatic stress disorder among elderly earthquake survivors: a focus on the February earthquake in Turkey.","authors":"Muhteşem Erol Yayla, Raziye Şule Gümüştakim, Duygu Ayhan Başer","doi":"10.1111/psyg.13201","DOIUrl":"10.1111/psyg.13201","url":null,"abstract":"<p><strong>Background: </strong>On 6 February, 2023, Turkey experienced a disaster resulting from two major earthquakes. The elderly population stands out as one of the most vulnerable and least adaptable. This study aims to identify the quality of life (QOL) and post-traumatic stress disorder (PTSD) symptoms among elderly earthquake survivors in Turkey.</p><p><strong>Methods: </strong>This research was conducted between 1 October, 2023 and 15 December, 2023 as a cross-sectional design. During the data collection process, survey questions prepared by the researchers (29 questions) and the Elderly Quality of Life Scale (OPQOL-Bref) and the Impact of Events Scale (IES-R) were used.</p><p><strong>Results: </strong>Three hundred and eighty-four elderly people participated in the study. PTSD was more common in those diagnosed with chronic diseases after the earthquake, in those who had a drug-free period after the earthquake, in those who smoked and quit smoking, and in those who started psychiatric medication after the earthquake. Post-traumatic stress was seen more frequently in those with low QOL scores and in those who had a longer period of not using medication after the earthquake. It was observed that QOL was better in married people, high school graduates, those with average income levels, those who did not have chronic diseases before and after the earthquake, those who did not have a drug-free period after the earthquake, those who were physically active, and those who did not use psychiatric medication after the earthquake.</p><p><strong>Conclusion: </strong>Chronic disease diagnosis post-earthquake, drug-free periods, smoking habits, and psychiatric medication usage were identified as influential factors in PTSD occurrence. Additionally, the study shed light on the profound effect of earthquake-related experiences, such as house damage, injuries, deaths in first-degree relatives, displacement, and changes in living conditions, on PTSD prevalence.</p>","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":" ","pages":"e13201"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overcoming barriers: addressing challenges in dementia care for Ukrainian refugees.","authors":"Nimra Javaid, Francesco Piacenza","doi":"10.1111/psyg.13211","DOIUrl":"10.1111/psyg.13211","url":null,"abstract":"","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":" ","pages":"e13211"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of social relationships and hearing impairments with behavioural and psychological symptoms of dementia in a Japanese memory clinic.","authors":"Saki Tanaka, Ryo Katayose, Sora Shimamura, Kayoko Fukui, Michio Ono, Yoshitomo Shirakashi, Teruaki Kawasaki, Ichiro Akiguchi, Mihoko Ogita","doi":"10.1111/psyg.13216","DOIUrl":"10.1111/psyg.13216","url":null,"abstract":"<p><strong>Background: </strong>Behavioural and psychological symptoms of dementia (BPSD) negatively impact the quality of life of patients with dementia and their surrounding caregivers. Therefore, identifying modifiable factors to prevent BPSD is crucial. This cross-sectional study investigated the association between hearing impairment (HI), social relationships, and BPSD.</p><p><strong>Methods: </strong>A survey involving 179 patients who attended a memory clinic was conducted between July 2023 and March 2024. Pure-tone audiometry and questionnaire interviews were conducted, while medical records were reviewed. HI was defined as an average hearing level ≥ 40 dB, measured by pure-tone audiometry using the better-hearing ear. BPSD presence and severity were assessed using the BPSD25Q-based questionnaire. Multiple regression analysis was used for calculating partial regression coefficients to assess the association between HI, social relationship indicators, and BPSD presence and severity, adjusting for confounders.</p><p><strong>Results: </strong>Among the 144 participants included in the analysis, the mean age was 82.7 years, and 96 (66.7%) were female individuals. Using multiple regression analysis, individuals with HI, whether living with others (β = 1.49, P = 0.038) or living alone (β = 2.23, P = 0.044) had a higher presence of BPSD, compared with those without HI who live with others. Additionally, those with HI who regularly engaged in conversations (β = 1.51, P = 0.027) or did not participate in social interactions (β = 2.02, P = 0.020) also had a higher presence of BPSD, compared with individuals without HI in similar circumstances. Similarly, those with HI and living alone (β = 4.54, P = 0.033) and lacking social interaction (β = 3.89, P = 0.020) experienced increased BPSD severity.</p><p><strong>Conclusion: </strong>Our findings indicated that living alone and lacking social interaction with having HI were linked to both the presence and severity of BPSD. Additionally, increased verbal communication through conversations with cohabiting family members and others in patients with HI was associated with a higher presence of BPSD. Reducing communication stress and maintaining social connections are essential for managing these challenges.</p>","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":" ","pages":"e13216"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-saccade can be used as a screening tool for early cognitive impairment: a correlation study based on anti-saccade parameters and cognitive function.","authors":"Liwen Yang, Lingmei Lu","doi":"10.1111/psyg.13215","DOIUrl":"10.1111/psyg.13215","url":null,"abstract":"<p><strong>Background: </strong>Eye movement tasks, especially anti-saccade tasks, have been used to assess cognitive function in patients with neuropsychiatric disorders. Although it has been shown that individuals with cognitive impairment perform worse on anti-saccades tasks, there is a lack of systematic evaluation of the sensitivity of parameters of anti-saccades to assess different subtypes of cognitive impairment.</p><p><strong>Methods: </strong>A total of 158 participants were enrolled in this study, consisting of 66 men and 92 women, with an average age of 50.2 ± 10 years. The comparison of pro-saccade reaction time, anti-saccade reaction time, and error rates in the saccade task between individuals with cognitive impairments and a normal group was conducted. Furthermore, we systematically analyzed the correlations between the performance in neurological function tests (Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Stroop) and these anti-saccade parameters. Especially, the correlation between these parameters and cognitive function in different domains of the MoCA task were also evaluated.</p><p><strong>Results: </strong>The pro-saccade reaction time, anti-saccade reaction time and error rate were negatively correlated with the MMSE and MoCA scores (P < 0.001), and positively correlated with the time used in Stroop tasks. Among them, the error rate had the strongest correlation with the performance of MMSE, MoCA and Stroop tasks (MoCA: P < 0.0001, r² = -0.608; MMSE: P < 0.0001, r² = -0.344; Stroop: P < 0.0001, r² = 0.455). Among the seven cognitive domains examined by the MoCA task, error rates had relatively high correlations with visuospatial/executive (P < 0.0001, r² = -0.4660) and delayed recall (P < 0.0001, r² = -0.4228) compared to naming, language (P = 0.0004, r² = -0.0788), attention (P = 0.0004, r² = -0.0780), abstraction (P < 0.0001, r² = -0.1515), orientation (P < 0.0001, r² = -0.1075). Moreover, pro-saccade reaction time, anti-saccade reaction time and error rate of people with high MoCA scores were significantly higher than those of people with low MoCA scores, which can be used to identify people with mild cognitive impairment.</p><p><strong>Conclusions: </strong>Our study's results provide valuable clinical evidence supporting the effectiveness of anti-saccades in assessing cognitive impairment, which is beneficial for screening and timely clinical intervention in individuals with specific cognitive impairment.</p>","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":" ","pages":"e13215"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of dementia in patients with age-related medical conditions: a retrospective cohort study.","authors":"Hee-Cheol Kim","doi":"10.1111/psyg.13222","DOIUrl":"10.1111/psyg.13222","url":null,"abstract":"<p><strong>Objective: </strong>This retrospective cohort study aimed to investigate the impact of age-related medical conditions on the incidence of dementia, considering factors such as hypertension, diabetes mellitus, cerebrovascular disease, cardiovascular disease, chronic kidney disease, osteoarthritis, osteoporosis, chronic obstructive pulmonary disease, and hearing difficulties.</p><p><strong>Methods: </strong>Data from 513 640 patients at Keimyung University Dongsan Hospital were analyzed using the Observational Medical Outcomes Partnership Common Data Model. Patients with and without age-related medical conditions were assigned to experimental and control groups, respectively, with propensity score matching. Cox proportional hazards models assessed the association between each condition and dementia incidence.</p><p><strong>Results: </strong>Hypertension, diabetes mellitus, cerebrovascular disease, cardiovascular disease, chronic kidney disease, osteoarthritis, osteoporosis, and hearing difficulties were associated with increased dementia risk. Chronic obstructive pulmonary disease showed no significant association with increased risk of dementia. Incidence rates ranged from 4.52 to 8.05 per 1000 person-years in the control group and 7.46 to 14.99 per 1000 person-years in the experimental group. Hazard ratios ranged from 1.38 to 2.36.</p><p><strong>Conclusions: </strong>The study highlights the importance of managing age-related medical conditions to mitigate dementia risk. Understanding these risk factors can inform preventive strategies and improve cognitive health outcomes. Problems with deidentification data analysis and the need for further multicentred studies are among the limitations of this study.</p>","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":" ","pages":"e13222"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142718096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the effectiveness of individual occupation-based reminiscence therapy at home and in a dementia care centre on cognitive function in older adults with mild dementia: a pilot randomised controlled trial.","authors":"Ha Yeong Jung, Jae Sung Kwon","doi":"10.1111/psyg.13204","DOIUrl":"10.1111/psyg.13204","url":null,"abstract":"<p><strong>Background: </strong>The need for research on individual home therapies to promote continued community-dwelling among older adults with mild dementia is growing. This study aimed to compare the effects of individual occupation-based reminiscence therapy at home (IOBRT-H) and individual occupation-based reminiscence therapy in a dementia care centre (IOBRT-DCC) on cognitive function, depression, and instrumental activities of daily living (IADL) among community-dwelling older adults with mild dementia.</p><p><strong>Methods: </strong>This study was a randomised controlled trial. Twenty-six community-dwelling older adults with mild dementia were randomised to the IOBRT-H (n = 13) and IOBRT-DCC (n = 13) groups. The intervention was conducted for 10 weeks, with one session a week and each session lasting 60 min for both groups. Cognitive function was assessed using the Allen Cognitive Level Screen (ACLS), depression with the short form of the Geriatric Depression Scale Korean version (SGDS-K), and IADL using the Seoul-Instrumental Activities of Daily Living (S-IADL).</p><p><strong>Results: </strong>Both the IOBRT-H and IOBRT-DCC groups showed significant improvements in ACLS scores (P < 0.01 and P < 0.01, respectively). The SGDS-K score decreased only in the IOBRT-H group (P < 0.01). Between the groups, the IOBRT-H group had significantly greater improvements in both ACLS and SGDS-K scores than the IOBRT-DCC group (P < 0.05 and P < 0.05, respectively).</p><p><strong>Conclusion: </strong>This study's results indicated the potential for applying IBORT-H as an intervention to improve cognitive function and reduce depression in community-dwelling older adults with mild dementia. We expect the findings of this study to serve as useful foundational data for developing home-visiting cognitive programs.</p>","PeriodicalId":74597,"journal":{"name":"Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society","volume":" ","pages":"e13204"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}