Precision cancer medicine最新文献

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Favouring quality improvement initiatives: the experience of the Belgian College of Radiation Oncology 支持质量改进举措:比利时放射肿瘤学学院的经验
Precision cancer medicine Pub Date : 2021-01-01 DOI: 10.21037/pcm-22-15
A. Vaandering, S. Roels, B. Yalvaç, N. Reulens, B. Reniers, F. Vanhoutte, V. Remouchamps, Y. Lievens, R. Weytjens
{"title":"Favouring quality improvement initiatives: the experience of the Belgian College of Radiation Oncology","authors":"A. Vaandering, S. Roels, B. Yalvaç, N. Reulens, B. Reniers, F. Vanhoutte, V. Remouchamps, Y. Lievens, R. Weytjens","doi":"10.21037/pcm-22-15","DOIUrl":"https://doi.org/10.21037/pcm-22-15","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47946789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uncommon EGFR mutations in non-small-cell lung cancer 非小细胞肺癌癌症中罕见的EGFR突变
Precision cancer medicine Pub Date : 2021-01-01 DOI: 10.21037/pcm-22-14
M. Russano, G. Perrone, G. D. Di Fazio, A. Galletti, F. Citarella, V. Santo, L. Brunetti, Alessia Vendittelli, B. Vincenzi, G. Tonini, D. Santini
{"title":"Uncommon EGFR mutations in non-small-cell lung cancer","authors":"M. Russano, G. Perrone, G. D. Di Fazio, A. Galletti, F. Citarella, V. Santo, L. Brunetti, Alessia Vendittelli, B. Vincenzi, G. Tonini, D. Santini","doi":"10.21037/pcm-22-14","DOIUrl":"https://doi.org/10.21037/pcm-22-14","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48826754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A narrative review of predictive and prognostic biomarkers in skin tumors 皮肤肿瘤预测和预后生物标志物的叙述性综述
Precision cancer medicine Pub Date : 2021-01-01 DOI: 10.21037/PCM-21-6
A. Stagner, R. Nazarian
{"title":"A narrative review of predictive and prognostic biomarkers in skin tumors","authors":"A. Stagner, R. Nazarian","doi":"10.21037/PCM-21-6","DOIUrl":"https://doi.org/10.21037/PCM-21-6","url":null,"abstract":"Merkel cell carcinoma (MCC), melanoma, and keratinocyte carcinomas (KC), basal cell carcinoma (BCC) and squamous cell carcinoma, are among the most common and/or aggressive malignancies of the skin. Traditional staging parameters remain the most important and widely utilized prognostic and predictive tools. However, given the recent explosion in the literature on immunohistochemical and molecular-genetic markers for these skin tumors, novel predictive and prognostic biomarkers are emerging. Herein, we sought to summarize well-established and emerging predictive and prognostic biomarkers in these cutaneous malignancies. We present the following article in accordance with the Narrative Review Reporting Checklist (available at: http:// dx.doi.org/10.21037/pcm-21-6).","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49232946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sporadic mesenteric desmoid-type fibromatosis with “double-hit” T41A and S45P beta-catenin mutation profile: a case report of an extremely rare event—clinically relevant or much ado about nothing? 具有“双重命中”T41A和S45Pβ-连环蛋白突变特征的散发性肠系膜硬纤维样纤维瘤病:一例极为罕见事件的病例报告——与临床相关还是小题大做?
Precision cancer medicine Pub Date : 2021-01-01 DOI: 10.21037/pcm-22-2
S. Shafi, Ashley Patton, A. Rogers, V. Grignol, S. Oghumu, O. Iwenofu
{"title":"Sporadic mesenteric desmoid-type fibromatosis with “double-hit” T41A and S45P beta-catenin mutation profile: a case report of an extremely rare event—clinically relevant or much ado about nothing?","authors":"S. Shafi, Ashley Patton, A. Rogers, V. Grignol, S. Oghumu, O. Iwenofu","doi":"10.21037/pcm-22-2","DOIUrl":"https://doi.org/10.21037/pcm-22-2","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41974915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Analytical Phase: Current Controls; Fit for Purpose Selection and Validation 分析阶段:电流控制;适合目的的选择和验证
Precision cancer medicine Pub Date : 2021-01-01 DOI: 10.1007/978-3-030-84087-7_10
Bharat Jasani, R. Huss, C. Taylor
{"title":"Analytical Phase: Current Controls; Fit for Purpose Selection and Validation","authors":"Bharat Jasani, R. Huss, C. Taylor","doi":"10.1007/978-3-030-84087-7_10","DOIUrl":"https://doi.org/10.1007/978-3-030-84087-7_10","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":"9 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50981054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of Precision Cancer Diagnostic Test 癌症精密诊断检测的实施
Precision cancer medicine Pub Date : 2021-01-01 DOI: 10.1007/978-3-030-84087-7_15
B. Jasani, R. Huss, C. Taylor
{"title":"Implementation of Precision Cancer Diagnostic Test","authors":"B. Jasani, R. Huss, C. Taylor","doi":"10.1007/978-3-030-84087-7_15","DOIUrl":"https://doi.org/10.1007/978-3-030-84087-7_15","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":"8 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50981351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of digital and integrative pathology for the detection of translocations: a narrative review 数字和综合病理学对易位检测的作用:叙述回顾
Precision cancer medicine Pub Date : 2021-01-01 DOI: 10.21037/pcm-21-56
C. Beretta, S. Ceola, F. Pagni, V. L’Imperio
{"title":"The role of digital and integrative pathology for the detection of translocations: a narrative review","authors":"C. Beretta, S. Ceola, F. Pagni, V. L’Imperio","doi":"10.21037/pcm-21-56","DOIUrl":"https://doi.org/10.21037/pcm-21-56","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48656826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Wielding a double-edged sword in head and neck cancers—diagnosis, risk factors and mitigation strategies of radiation-induced head and neck sarcomas: a narrative review 在头颈部癌症中挥舞双刃剑——辐射诱发的头颈部肉瘤的诊断、危险因素和缓解策略:一项叙述性综述
Precision cancer medicine Pub Date : 2021-01-01 DOI: 10.21037/pcm-21-30
T. Chan, Venkatesh Alagappan, B. Vellayappan
{"title":"Wielding a double-edged sword in head and neck cancers—diagnosis, risk factors and mitigation strategies of radiation-induced head and neck sarcomas: a narrative review","authors":"T. Chan, Venkatesh Alagappan, B. Vellayappan","doi":"10.21037/pcm-21-30","DOIUrl":"https://doi.org/10.21037/pcm-21-30","url":null,"abstract":"National University Cancer Institute, Singapore, Singapore; Novi High School, Novi, MI, USA Contributions: (I) Conception and design: TY Chan, B Vellayappan; (II) Administrative support: All authors; (III) Provision of study materials or patients: TY Chan, B Vellayappan; (IV) Collection and assembly of data: TY Chan, B Vellayappan; (V) Data analysis and interpretation: TY Chan, B Vellayappan; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Balamurugan Vellayappan. 1E Kent Ridge Road, Level 7 Tower Block, Singapore 119228, Singapore. Email: bala_vellayappan@nuhs.edu.sg.","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47713245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
KRAS G12V mutation as an acquired resistance mechanism after treatment with dabrafenib and trametinib in non-small cell lung cancer harbouring the BRAF V600E mutation: a case report KRAS G12V突变作为携带BRAF V600E突变的癌症用达非尼和曲美替尼治疗后获得性耐药性机制的一例报告
Precision cancer medicine Pub Date : 2021-01-01 DOI: 10.21037/pcm-21-55
H. Oi, K. Yoh, S. Matsumoto, H. Izumi, Y. Shibata, T. Sakai, K. Nosaki, Y. Zenke, K. Goto
{"title":"KRAS G12V mutation as an acquired resistance mechanism after treatment with dabrafenib and trametinib in non-small cell lung cancer harbouring the BRAF V600E mutation: a case report","authors":"H. Oi, K. Yoh, S. Matsumoto, H. Izumi, Y. Shibata, T. Sakai, K. Nosaki, Y. Zenke, K. Goto","doi":"10.21037/pcm-21-55","DOIUrl":"https://doi.org/10.21037/pcm-21-55","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43750034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lung cancer in women 女性肺癌
Precision cancer medicine Pub Date : 2021-01-01 DOI: 10.21037/pcm-22-32
E. Baldini
{"title":"Lung cancer in women","authors":"E. Baldini","doi":"10.21037/pcm-22-32","DOIUrl":"https://doi.org/10.21037/pcm-22-32","url":null,"abstract":"","PeriodicalId":74487,"journal":{"name":"Precision cancer medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44171323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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