Porto biomedical journal最新文献

{"title":"Determinants of frequent use of open consultations: a study on patient demographics, chronic conditions, and utilization patterns in primary care.","authors":"Cláudia A Leitão, Sílvia R Santos, Ana S Aguiar, Vera L Sousa, Helder A Lanhas, Filipe M Alves","doi":"10.1097/j.pbj.0000000000000282","DOIUrl":"10.1097/j.pbj.0000000000000282","url":null,"abstract":"<p><p>In Portugal, open consultations (OCs) in primary health care address urgent medical needs, constituting 40-50% of family doctor activity. Frequent attenders (FAs), often presenting nonacute issues, significantly contribute to health care overuse. This study aimed to identify factors associated with frequent OC use in a primary health care unit during 2022. A retrospective cross-sectional analysis was conducted on 4,269 adult patients, with frequent attendance defined as four or more consultations (≥90th percentile). Sociodemographic and clinical factors, including age, sex, employment, chronic conditions, and multimorbidity, were examined using binomial logistic regression. FAs (n = 570, 13.4%) accounted for 36.2% of all consultations. Significant associated variables included female sex (OR = 1.417), economic insufficiency (OR = 1.323), and multimorbidity (OR = 1.678). Conditions such as musculoskeletal (OR = 2.146), psychological (OR = 2.040), and neurological (OR = 1.550) disorders were strongly linked to frequent attendance. While FAs represent a minority of patients, their disproportionate use of OC services underscores the need for targeted interventions, such as individualized care plans and resource optimization, to balance demand and availability. These findings highlight critical areas for policy and practice to enhance health care efficiency.</p>","PeriodicalId":74479,"journal":{"name":"Porto biomedical journal","volume":"10 2","pages":"e282"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eating behavior and physical activity in relation to obesity among medical students at Mansoura University, Egypt.","authors":"Amira S Nowara, Hend Magdy, Mervat M El-Eshmawy","doi":"10.1097/j.pbj.0000000000000281","DOIUrl":"10.1097/j.pbj.0000000000000281","url":null,"abstract":"<p><strong>Background/aim: </strong>Medical students are subjected to the risk of obesity due to various factors. Understanding behavioral issues may provide an important insight into obesity development, prevention, and treatment. Emotional, uncontrolled, and restrictive eating practices are problematic eating behaviors characterized by food intake independent of hunger but based on emotional state. Limited data from Egypt are currently available; therefore, this study was undertaken with the objective to find the frequency of overweight and obesity among medical students at Mansoura University, Egypt. Eating behavior and physical activity in relation to overweight/obesity were also assessed.</p><p><strong>Methods: </strong>A total of 368 undergraduate medical students were included in this study. Eating behavior was described using the French translation of Three-Factor Eating Questionnaire-R18. Obesity and physical activity were assessed according to WHO recommendations.</p><p><strong>Results: </strong>Among the total students, 54% were normal weight, 32% were overweight, 9% were obese class I, 2% were obese class II, 1% were obese class III, and 2% were underweight. Overweight/obese students had significantly lower physical activity than nonoverweight/obese. Cognitive restraint, uncontrolled eating, and emotional eating were significantly higher in overweight/obese compared with nonoverweight/obese students. Cognitive restraint, uncontrolled eating, and emotional eating were significantly correlated with body mass index. Uncontrolled eating was negatively correlated with sex and residence, whereas emotional eating was negatively correlated with physical activity. Female sex, physical inactivity, increased cognitive restraint, and increased emotional eating scores were significant predictors of obesity in the studied medical students.</p><p><strong>Conclusion: </strong>Medical students are likely to be overweight or obese. The main risk factors associated with overweight and obesity are female sex, lack of physical activity, and cognitive and emotional restraint but not uncontrolled eating.</p>","PeriodicalId":74479,"journal":{"name":"Porto biomedical journal","volume":"10 2","pages":"e281"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11872364/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicopathological correlates of vitamin D receptor expression in prostate cancer: results of genomic analysis.","authors":"Sebastian A Omenai, Henry O Ebili, Uchenna S Ezenkwa, Ayotunde O Ale, Patrick A Akintola, Adesoji E Adetona, Chima U Akunwata, Mbwas I Mashor, Ifeanyichukwu D Nwanji, Oluwadamilare Iyapo, Chinedu A Ezekekwu, John C Akulue, Ngozi Chidozie, Ifeanyi J Nwadiokwu","doi":"10.1097/j.pbj.0000000000000280","DOIUrl":"10.1097/j.pbj.0000000000000280","url":null,"abstract":"<p><strong>Objectives: </strong>Prostate cancer (PCa) is the most common malignancy in men. Geography and environmental factors have been associated with varying incidence and mortalities in different groups. Vitamin D has antiproliferative effect on PCa cells, and its effect is mediated through vitamin D receptor (VDR). This study reported the correlation of VDR expression with some clinicopathological and biological features among a cohort of patients with PCa.</p><p><strong>Methods: </strong>Genomic and clinicopathological data of 497 patients with PCa reposited in The Cancer Genome Atlas were retrieved using Linux command in running codes and scripts and extrapolated onto SPSS version 28 for statistical analysis. Descriptive and inferential statistics were conducted to determine the proportions and associations of VDR expression with genomic variables and clinicopathological indices. The mechanism of VDR dysregulation was also interrogated.</p><p><strong>Results: </strong>Our results showed that high VDR expression was positively correlated with a high Gleason score (<i>P</i> < 0.001), poorer prognostic International Society of Urological Pathology grade groups (<i>P</i> < 0.001), advanced tumor stage (<i>P</i> = 0.01), and poorer response to androgen deprivation therapy (ADT). Age, race, and overall and disease-free survival did not show any correlation with VDR expression (<i>P</i> > 0.05). Furthermore, the major mechanism of dysregulation of VDR in PCa was by aberrant methylation of the VDR promoter region (<i>P</i> < 0.001), and not by copy number alterations (<i>P</i> = 0.42).</p><p><strong>Conclusion: </strong>VDR expression is associated with adverse clinicopathological indices, including late-stage disease profile, high-grade indices, and poorer response to ADT. VDR is also mainly deregulated by aberrant epigenetic mechanism. The study is limited by absence of some clinical information such as sunlight exposure.</p>","PeriodicalId":74479,"journal":{"name":"Porto biomedical journal","volume":"10 1","pages":"e280"},"PeriodicalIF":0.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11828007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing response to stressful emotions: a controlled crossover study using pupillometry.","authors":"Ana Carolina Noronha, Francisca Castro Mendes, Pedro Carvalho, Mafalda Fonseca, Inês Paciência, André Moreira","doi":"10.1097/j.pbj.0000000000000279","DOIUrl":"10.1097/j.pbj.0000000000000279","url":null,"abstract":"<p><strong>Background: </strong>Fear and horror induce autonomic protective responses, acting as \"survival intelligence.\" Pupillometry is an innovative method that captures real-time autonomic nervous system reactions to stress.</p><p><strong>Objective: </strong>To evaluate the feasibility of pupillometry to assess the acute response to a passive real-life stressor-viewing a truthful war scene.</p><p><strong>Methods: </strong>Thirteen medical students (10 women) with an average age of 20.4 years were enrolled in a nonrandomized controlled crossover trial. Selected clips from two different audiovisual stimuli (M1: <i>Saving Private Ryan</i> as a fear and horror inducer and M2: <i>Life Is Beautiful</i> as a control) were watched for 15 minutes, separated by a washout period of 48-72 hours. The differences in pupillometry parameters between the exposure movie and the assessment time (T0 and T1 for M1 and T0 and T1 for M2) were evaluated using a Wilcoxon test. The Wilcoxon test was also used to assess the difference between M1 and M2 within each assessment time point (T0 and T1).</p><p><strong>Results: </strong>A significant difference in response to acute fear and horror-induced stress was observed in pupillometry parameters {baseline [6.90 (5.95; 7.40) vs. 6.60 (5.55; 7.10), <i>P</i> = 0.030] and final pupil diameter [4.50 (3.90; 5.20) vs. 4.10 (3.50; 4.60), <i>P</i> = 0.012]} between M1 and M2 in T1, suggesting the acute increase in sympathetic parameters. Although not significant, there was also a difference in pupillometry parameters (final pupil diameter [<i>P</i> = 0.060], average constriction velocity [<i>P</i> = 0.059]) after watching M1 compared with T0.</p><p><strong>Conclusion: </strong>Our proof-of-concept study suggests that pupillometry may be used to evaluate changes in the activity of the autonomic nervous system induced by an acute passive stress stimulus.</p>","PeriodicalId":74479,"journal":{"name":"Porto biomedical journal","volume":"10 1","pages":"e279"},"PeriodicalIF":0.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron deficiency in acute coronary syndromes: prevalence and prognostic impact.","authors":"Ana Fátima Esteves, Sara Gonçalves, Tatiana Duarte, Joana Ferreira, Rui Coelho, Jéni Quintal, Catarina Pohle, Nuno Fonseca, Rui Caria","doi":"10.1097/j.pbj.0000000000000278","DOIUrl":"https://doi.org/10.1097/j.pbj.0000000000000278","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>Iron deficiency (ID) is a well-known prognostic marker in heart failure (HF), independent of anemia. However, its impact in acute coronary syndromes (ACSs) is not well established.</p><p><strong>Methods: </strong>This is a retrospective analysis of patients admitted with ACS from January to December 2019. The population was evaluated according to basal characteristics and divided in two groups, with or without ID, compared according to several variables, namely demographic, index hospitalization, comorbidities, analytical and echocardiographic. We determined their predictive value on the occurrence of hemorrhage or need for red blood cell transfusion, all-cause hospitalizations, and all-cause death.</p><p><strong>Results: </strong>We included 287 patients, with median age 66 (interquartile range [IQR] 21) years and 72% male. ID was present in 48% of patients. Most presented with ST-elevation myocardial infarction (STEMI) (57%), and 13% were admitted in Killip-Kimball class III or IV. Almost 40% had a left ventricle ejection fraction < 50% on admission. Patients with non-ST-elevation myocardial infarction presented more frequently with ID, compared with patients with STEMI. Of note, 33% of patients with ID had concomitant anemia. During a median follow-up of 28 (IQR 7) months, 10% had an urgent care admission for HF, 7% were hospitalized for HF, and 18% died. There was a significantly higher rate of emergency department admissions for HF in the group with ID. Age, anemia, and NT-proBNP levels predicted the occurrence of all-cause death, with ID having no impact on none of the evaluated events.</p><p><strong>Conclusion: </strong>ID was prevalent in patients with ACS, affecting almost half of the population. In the acute setting of an ACS, anemia seems to have a greater impact on mortality and the role of ID in promoting HF needs further investigation.</p>","PeriodicalId":74479,"journal":{"name":"Porto biomedical journal","volume":"10 1","pages":"278"},"PeriodicalIF":0.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platelet distribution width-a prognosis marker in patients with chronic heart failure.","authors":"Ana Neves, Rita Gouveia, Sérgio Madureira, Catarina Elias, Pedro Ribeirinho-Soares, Marta Soares-Carreira, Joana Pereira, Jorge Almeida, Patrícia Lourenço","doi":"10.1097/j.pbj.0000000000000277","DOIUrl":"https://doi.org/10.1097/j.pbj.0000000000000277","url":null,"abstract":"<p><strong>Background: </strong>Increased levels of platelet distribution width (PDW) can predict cardiac death and infarction recurrence in acute myocardial infarction. PDW appears to be a prognosis marker in acute heart failure (HF); however, its impact on chronic HF is still unknown. We investigated the impact of PDW on chronic HF.</p><p><strong>Methods: </strong>We retrospectively analyzed outpatients with chronic HF with left ventricular systolic dysfunction (LVSD) from January 2012 to May 2018. Patients with no data on PDW levels or with preserved or recovered ejection fraction were excluded. The primary end point was all-cause mortality. Multivariable Cox regression analysis was used to evaluate the association between PDW and mortality. A multivariate model was built adjusting for age, sex, comorbidities, brain-type natriuretic peptide, New York Heart Association (NYHA) class, evidence-based therapy, and severity of LVSD.</p><p><strong>Results: </strong>In our cohort of 766 patients, 65.7% were male, the mean age was 70 years, and 35.4% were in NYHA class I; 38.3% had diabetes mellitus, 51.4% had severe LVSD, and 3.9% had an inflammatory or autoimmune disease. The median (interquartile range) PDW was 13.5 (12.1-14.9) fL. During a median follow-up of 49 (30-79) months, 372 patients (48.6%) died. Patients with PDW ≥ 14.3 fL presented a multivariate-adjusted higher risk of all-cause death than those with lower values (hazard ratio: 1.32, 95% confidence interval [CI]: 1.05-1.64, <i>P</i> = .2).</p><p><strong>Conclusions: </strong>Patients with PDW ≥14.3 fL (upper tercile for PDW) presented a multivariate-adjusted 32% (95% CI: 5-64%) higher risk of all-cause death than those with lower values. PDW can help clinicians stratify patients with chronic HF; it is a practical, inexpensive, and widely available parameter.</p>","PeriodicalId":74479,"journal":{"name":"Porto biomedical journal","volume":"10 1","pages":"277"},"PeriodicalIF":0.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diet and special educational needs (SENs) among children and adolescents: a systematic review.","authors":"Lúcia Nova, Rui Poínhos, Beatriz Teixeira","doi":"10.1097/j.pbj.0000000000000276","DOIUrl":"10.1097/j.pbj.0000000000000276","url":null,"abstract":"<p><p>Special educational needs (SENs) refer to children and adolescents needing additional educational support. Diet during pregnancy and pediatric age can influence the prevalence/severity of symptoms in SEN-related conditions/disabilities. This review aims to summarize associations between (i) pregnant women's diet and the prevalence of SEN-related conditions/disabilities among children/adolescents and (ii) the diet of children/adolescents with SEN-related conditions/disabilities and their symptomatology/well-being. A literature search was performed on Medline and Scopus, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The following inclusion criteria were considered, for each aim: (i) children/adolescents aged 19 years and younger, pregnant women's diet/nutrition, and diagnosis of SEN-related conditions/disabilities in children/adolescents; (ii) children/adolescents aged 19 years and younger, children/adolescents' diet/nutrition, and symptomatology/well-being of children/adolescents with SEN-related conditions/disabilities. 87 articles were included, referring to 10 different SEN-related conditions/disabilities, from which attention-deficit/hyperactivity disorder (ADHD) (41 articles) and autism spectrum disorder (ASD) (34 articles) stand out. Noteworthy results were seen regarding maternal caffeine consumption; pregnant woman multivitamin supplementation, high-sugar foods, and beverage intake during childhood/adolescence; maternal breastfeeding; and vitamin D supplementation. Despite the notable associations, further research using more standardized and homogeneous methodologies is needed to strengthen these findings. PROSPERO registration number: CRD42022313235.</p>","PeriodicalId":74479,"journal":{"name":"Porto biomedical journal","volume":"9 6","pages":"276"},"PeriodicalIF":0.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From the armchair to contemporary cardiac rehabilitation: the remarkable ongoing journey of exercise training in ischemic heart disease.","authors":"Eduardo M Vilela, Marta Catarina Almeida, Cláudia Oliveira, Teresa Nogueira, Susana Torres, Madalena Teixeira, Francisco Sampaio, José Ribeiro, Marco Oliveira, Nuno Bettencourt, Sofia Viamonte, Ricardo Fontes-Carvalho","doi":"10.1097/j.pbj.0000000000000273","DOIUrl":"10.1097/j.pbj.0000000000000273","url":null,"abstract":"<p><p>Exercise is an important physiological activity with several health benefits. In the setting of ischemic heart disease (IHD), the view toward exercise has greatly evolved throughout the years, concurrently to several major advances in the management of this complex entity. Currently, exercise training has broad applications across the IHD continuum as a powerful tool in its overall management, being a core component of comprehensive cardiac rehabilitation programs. Beyond this, exercise has also been incorporated as an integral part of contemporary methodologies aiming to provide diagnostic and prognostic data, such as cardiopulmonary exercise stress testing or stress echocardiography. In this article, we provide a pragmatic overview concerning the role of exercise in IHD, with a focus on its incorporation in cardiac rehabilitation frameworks, while also discussing some of the challenges and unmet needs concerning these interventions.</p>","PeriodicalId":74479,"journal":{"name":"Porto biomedical journal","volume":"9 6","pages":"273"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum total bilirubin is a risk factor of metabolic syndrome and its components in obese Egyptians.","authors":"Mervat M El-Eshmawy, Nancy Mahsoub, Ibrahim Elsehely","doi":"10.1097/j.pbj.0000000000000275","DOIUrl":"10.1097/j.pbj.0000000000000275","url":null,"abstract":"<p><strong>Background/aim: </strong>The link between serum total bilirubin and metabolic syndrome and its components has been previously proposed. However, it is unknown whether total bilirubin is a risk factor of metabolic syndrome and its components in obese Egyptians. Therefore, this study was conducted to clarify the association of total bilirubin levels with metabolic syndrome and its components in obese Egyptians.</p><p><strong>Methods: </strong>A total of 200 adults with obesity were enrolled in this study. Obese participants were evaluated for metabolic syndrome; there were 92 obese participants with metabolic syndrome and 108 obese participants without metabolic syndrome. Anthropometric measurements, fasting blood glucose (FBG), fasting insulin, homeostasis model assessment of insulin resistance (HOMA-IR), HOMA-β (%), lipid profile, uric acid, alanine aminotransferase, aspartate aminotransferase, and serum total bilirubin were assessed.</p><p><strong>Results: </strong>Total bilirubin was significantly lower in obese participants with metabolic syndrome than in those without metabolic syndrome. Compared with middle bilirubin tertile, high and low bilirubin tertiles were independently associated with metabolic syndrome. Regarding metabolic syndrome components, a significant positive association between low bilirubin tertile and hypertension was found independent of the all studied confounding factors, whereas the association of total bilirubin level with waist circumference (WC), FBG, high-density lipoprotein cholesterol, and triglycerides was dependent on body mass index (BMI), HOMA-IR, and high sensitive C-reactive protein (hs-CRP).</p><p><strong>Conclusion: </strong>Total bilirubin is an independent risk factor of metabolic syndrome in obese Egyptians. We have found an independent association between high bilirubin level and reduced risk of metabolic syndrome, whereas low bilirubin level was associated with increased risk of metabolic syndrome. Bilirubin is also independently associated with hypertension, but its association with other components of metabolic syndrome is mainly dependent on BMI, HOMA-IR, and hs-CRP.</p>","PeriodicalId":74479,"journal":{"name":"Porto biomedical journal","volume":"9 6","pages":"274"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare extranodal NK/T-cell lymphoma: a diagnostic challenge and therapeutic approach.","authors":"Sofia Moura de Azevedo, Francisco Sousa, Rita Peixeiro, Manuela Bertão","doi":"10.1097/j.pbj.0000000000000274","DOIUrl":"10.1097/j.pbj.0000000000000274","url":null,"abstract":"","PeriodicalId":74479,"journal":{"name":"Porto biomedical journal","volume":"9 6","pages":"274"},"PeriodicalIF":0.0,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11560117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}