{"title":"Effect of Inpatient Cardiac Rehabilitation Combined with Waon Therapy on Exercise Capacity in Elderly Patients with Heart Failure: A Pilot Study.","authors":"Kazuya Yamamoto, Takumi Noda, Koichi Ito, Hiroyuki Miura, Makoto Murata, Chiaki Yokota","doi":"10.1298/ptr.E10322","DOIUrl":"10.1298/ptr.E10322","url":null,"abstract":"<p><strong>Objectives: </strong>Inpatient cardiac rehabilitation (CR) and pharmacotherapy are important for better in-hospital outcomes in elderly heart failure (HF) patients. We aimed to examine whether conventional CR combined with Waon therapy (Waon-CR) improves exercise capacity compared to CR alone in elderly HF patients.</p><p><strong>Methods: </strong>Decompensated and hospitalized HF patients who could not walk independently over 200 m were recruited. Patients admitted from May 2020 to March 2021 and from April 2021 to March 2024 were included in the CR and Waon-CR groups, respectively. Participants underwent a 5-session program during hospitalization. The main outcome measure was a 6-minute walk distance (6MWD) at the completion of the program. We also investigated exercise-related adverse events.</p><p><strong>Results: </strong>A total of 34 patients (mean age 79.5 years, 13 males) were enrolled, including 18 patients in the CR group and 16 patients in the Waon-CR group. The 6MWD after the 5-session program was longer in the Waon-CR group than in the CR group (362.2 ± 103.7 vs. 286.3 ± 100.6 m, p = 0.038). Significant improvement of the 6MWD was demonstrated in the Waon-CR group after adjusting for confounding factors (adjusted B, 147.0 m; 95% confidence interval, 41.3-252.8 m, p = 0.012). There were no adverse events during the hospital stay.</p><p><strong>Conclusions: </strong>Inpatient Waon-CR was feasible and led to improved 6MWD in elderly HF patients at the completion of the 5-session program.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"28 2","pages":"99-105"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445360/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daiki Matsuzaka, Koki Wagatsuma, Takenori Shimada, Kenta Ikushima, Hiroyuki Fujisawa
{"title":"Reliability and Validity of Observational Gait Analysis by Physical Therapists: Possibility of Verifying Accuracy and Improving Technology in Visual Measurement of Joint Angles.","authors":"Daiki Matsuzaka, Koki Wagatsuma, Takenori Shimada, Kenta Ikushima, Hiroyuki Fujisawa","doi":"10.1298/ptr.E10342","DOIUrl":"10.1298/ptr.E10342","url":null,"abstract":"<p><strong>Objectives: </strong>The reliability of observational gait analyses is generally considered poor or moderate. This is considered due to the drawbacks in the experimental designs and measurement methods used in related studies. This study examined the reliability and validity of physical therapists' (PTs) visual joint angle estimation in gait analysis with a rigorous design.</p><p><strong>Methods: </strong>Twenty PTs were divided into 2 groups of 10 each based on their experience: <10 years and >10 years. They observed videos and still images of patients with gait disorders and visually estimated the joint angles at specific points during the gait cycle. Reliability was assessed using the intraclass correlation coefficient, and validity was assessed by a correlation analysis, which compared their estimates with reference values obtained from the digital video analysis.</p><p><strong>Results: </strong>Intra-rater reliability for visual estimation using video tended to exceed 0.6 for most indicators, whereas inter-rater reliability ranged from 0.04 to 0.59. For validity, correlation coefficients indicated an accuracy of 0.06-0.62 for video and 0.08-0.68 for still images.</p><p><strong>Conclusions: </strong>Although intra-rater reliability tended to be higher than inter-rater reliability, neither reached levels considered sufficiently reliable, and validity showed only limited agreement with reference values. These results highlight the limitations of visual estimation in joint angle assessment. Future efforts should focus not only on improving observational consistency but also on improving agreement with reference values through corrective training using still images.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"28 2","pages":"129-136"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between Physical Function at Discharge and Fall Frequency One Month after Discharge in Patients with Progressive Supranuclear Palsy.","authors":"Yutaro Sato, Hideki Yoshida, Keisuke Ota, Kyoko Hamada, Naoto Ishikawa, Ryo Matsuda","doi":"10.1298/ptr.25-E10361","DOIUrl":"10.1298/ptr.25-E10361","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to investigate the relationship between fall frequency and progressive supranuclear palsy (PSP) severity, walking ability, balance function, cognitive function, and frontal lobe function in patients with PSP.</p><p><strong>Methods: </strong>The study included 54 patients with PSP. Multiple logistic regression analysis was conducted to examine whether PSP severity, walking ability, balance function, cognitive function, and frontal lobe function after discharge were associated with fall frequency (falling two or more times per month). Balance function was assessed using the Berg Balance Scale and Mini-Balance Evaluation Systems Test (Mini-BESTest), with each used as an independent variable in separate models for association analysis. The Mini-BESTest showed a significant association, and its subitems were further analyzed using multiple logistic regression analysis.</p><p><strong>Results: </strong>A significant association was observed between the Mini-BESTest and fall frequency, and among its subitems, anticipatory postural adjustments were significantly associated with fall frequency.</p><p><strong>Conclusions: </strong>In patients with PSP characterized by impaired postural reflexes, the anticipatory postural adjustment ability may be associated with fall frequency.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"28 3","pages":"215-224"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12778350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phase Angle as a Predictor of Walking Independence in Patients Undergoing Stroke Rehabilitation: A Preliminary Study.","authors":"Naoya Ikeda, Yasuhiro Minamimura","doi":"10.1298/ptr.25-E10354","DOIUrl":"10.1298/ptr.25-E10354","url":null,"abstract":"<p><strong>Objectives: </strong>This study examined the relationship between phase angle (PhA), an indicator of muscle quality, and independent walking in stroke patients. The objective was to determine the predictive value of a PhA at admission for walking independence at discharge.</p><p><strong>Methods: </strong>This study included 220 stroke patients (121 males, 99 females), categorized based on their functional independence measure (FIM) mobility scores at discharge: independent (FIM ≥6; n = 100) and dependent (FIM ≤5; n = 120). Logistic regression analysis assessed whether PhA at admission predicted ambulatory independence at discharge. Additionally, receiver-operating characteristic curve analysis determined optimal cutoff values.</p><p><strong>Results: </strong>Logistic regression analysis showed that PhA at admission and the National Institutes of Health Stroke Scale (NIHSS) were significant predictors of independent walking. The optimal cutoff values for PhA were determined to be 4.35° for men and 4.1° for women. Similarly, the cutoff scores for the NIHSS were 7.5 points for men and 5.5 points for women.</p><p><strong>Conclusions: </strong>In stroke patients, PhA and NIHSS at admission were significantly associated with ambulatory independence at discharge. Evaluation of PhA and NIHSS at admission may be useful for more accurate prediction of gait outcomes.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"28 3","pages":"174-180"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12778351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Scoping Review of Minimal Important Change and Minimal Detectable Change of the Fugl-Meyer Assessment Lower Extremity Scale in Patients with Stroke.","authors":"Tetsuharu Nakazono, Satoru Amano, Kazuya Saita, Kayoko Takahashi","doi":"10.1298/ptr.E10324","DOIUrl":"10.1298/ptr.E10324","url":null,"abstract":"<p><strong>Objectives: </strong>In stroke rehabilitation, the Fugl-Meyer Assessment Lower Extremity (FMA-LE) motor scale is widely used to assess consecutive recovery steps from motor paralysis and predict prognosis after stroke. However, there has been limited opportunity to refer to the useful yet few studies that evaluated the minimal important change (MIC) and the minimal detectable change (MDC) of the FMA-LE motor scale. The aims of this review were to: (1) identify studies that have estimated the MIC and MDC, (2) identify the calculated MIC and MDC values and disease phases in previous studies, and (3) assess the methodological quality of the MIC and MDC studies of the FMA-LE motor scale.</p><p><strong>Methods: </strong>A scoping review was undertaken following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) recommendations. 3 databases (PubMed, CINAHL, and Web of Science) were used for the literature search. Reports of the MIC and MDC of the FMA-LE motor scale in patients with stroke were selected.</p><p><strong>Results: </strong>6 studies were included after confirming their eligibility. In the acute phase, inter-rater MDC was 3.23 points. In the early subacute phase, intra-rater MDC was 1.24 points. In the chronic phase, intra-rater MDC was 3.80, 4.87, and 7.98 points, inter-rater MDC was 3.57 and 5.96 points, and MIC was 6.00 points.</p><p><strong>Conclusion: </strong>No late subacute threshold was identified for the MDC, and no acute or subacute threshold was identified for the MIC. Compared with the quality of the MIC study, there is room for improvement in the quality of the MDC studies with respect to study design.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"28 2","pages":"137-144"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiac Rehabilitation Exercise in Korea.","authors":"Yun-Cheol Ha, Nan-Soo Kim","doi":"10.1298/ptr.R0034","DOIUrl":"10.1298/ptr.R0034","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to systematically review exercise-based cardiac rehabilitation (CR) programs implemented in South Korea since their inclusion in the National Health Insurance System in 2017.</p><p><strong>Methods: </strong>A systematic literature search was conducted using international and Korean databases for studies published after January 2017. The inclusion criterion was exercise-based CR intervention in patients with cardiac disease in South Korea. The methodological quality of each study was assessed using the Physiotherapy Evidence Database scale.</p><p><strong>Results: </strong>A total of 11 studies met our inclusion criteria. Most CR programs are hospital-based, whereas some incorporate home-based, aquatic, or forest environments. The exercise prescriptions followed the FITT (frequency, intensity, time, and type) principle and often included aerobic and high-intensity interval training. The reported outcomes included improvements in cardiopulmonary fitness, physical activity, and psychological well-being. Despite their clinical effectiveness, participation in CR programs remains low in Korea owing to accessibility and institutional limitations.</p><p><strong>Conclusions: </strong>Exercise-based CR programs in Korea demonstrated clinical benefits and diversified delivery models. Further efforts are required to enhance accessibility and promote wider adoption through policy and infrastructure development.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"28 2","pages":"85-91"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of Neuromuscular Electrical Stimulation on Quadriceps Muscle Strength in the Early Postoperative Period after Total Knee Arthroplasty.","authors":"Shigeki Sakai, Masanori Watanabe, Yuta Itoh, Nahoko Sato, Naoya Hamaguchi, Makoto Fukuta","doi":"10.1298/ptr.E10327","DOIUrl":"https://doi.org/10.1298/ptr.E10327","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to determine whether neuromuscular electrical stimulation (NMES) of the quadriceps muscle early after total knee arthroplasty (TKA) is effective in improving muscle strength.</p><p><strong>Methods: </strong>This was a single-center, non-blinded, randomized controlled trial involving 37 patients (60 knees) who underwent TKA. Patients were randomly assigned to either the intervention group (19 patients, 30 knees) or the control group (18 patients, 30 knees). Both groups received standard rehabilitation starting on postoperative day 1. Additionally, the intervention group received NMES therapy starting on postoperative day 2. NMES was administered at the highest tolerable intensity for 15 min per session (10-s stimulation and 10-s rest) twice daily for 4 weeks. Outcome measures included voluntary isometric quadriceps strength, knee joint range of motion (ROM), visual analog scale (VAS), and the Timed Up and Go (TUG) test, which were assessed preoperatively and at 4, 8, and 12 weeks postoperatively. The outcomes were compared between the two groups.</p><p><strong>Results: </strong>Both groups showed improvements in all outcomes over time. However, no significant differences were observed between the two groups (muscle strength: p = 0.412, flexion ROM: p = 0.668, extension ROM: p = 1.000, VAS score: p = 0.192, TUG test score: p = 0.296) (p-values are main effects of group factors in the split-plot analysis of variance).</p><p><strong>Conclusions: </strong>NMES in the early postoperative period after TKA did not provide significant additional functional recovery benefits compared with standard rehabilitation.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"28 1","pages":"54-60"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12047048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Measuring Tidal Volume with Diaphragm Movement and Chest Circumference.","authors":"Akihiro Kakuda","doi":"10.1298/ptr.E10318","DOIUrl":"https://doi.org/10.1298/ptr.E10318","url":null,"abstract":"<p><strong>Objective: </strong>The movement of the diaphragm plays an important role in respiration. In this study, we proposed and validated a new method for estimating the volume of a single ventilation (representing the tidal volume [VT]) from the vertical distance of diaphragmatic movement and thoracic circumference.</p><p><strong>Method: </strong>Diaphragm excursion (DE) was measured in healthy adult subjects via ultrasound, and the thoracic cavity volume change was estimated based on DE and thoracic circumference. Moreover, we measured the VT obtained by an expiratory gas analyzer and examined the relationships between DE and thoracic volume change (TVC) and between DE and VT.</p><p><strong>Results: </strong>The results showed that a correlation (ρ = 0.609) existed between DE and VT, and an even higher correlation existed between TVC and VT. TVC correlated better with the product of thoracic circumference squared and DE (ρ = 0.839) than with the product of thoracic circumference and DE as an alternative index (ρ = 0.746).</p><p><strong>Conclusion: </strong>Our findings demonstrate that, taking into account body size in addition to DE, changes in thoracic cavity volume are useful predictors of VT and provide an alternative measure for assessing the respiratory function, which will improve clinical and research practice in respiratory care.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"28 1","pages":"31-36"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12047049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Associations between Physical Activity, Sedentary Time, and Locomotive Syndrome Differ by Age and Sex: A Cross-sectional Study.","authors":"Wataru Nakano, Etsuko Ozaki, Michitaka Kato, Satoko Nakano, Kazuya Kito, Teruhide Koyama","doi":"10.1298/ptr.E10330","DOIUrl":"10.1298/ptr.E10330","url":null,"abstract":"<p><strong>Objectives: </strong>Physical activity is a relevant factor for the locomotive syndrome (LS); however, the association between intensity of physical activity and LS is unclear. This study aimed to investigate the associations among different intensities of physical activity (vigorous, moderate, and light), sedentary time, and LS.</p><p><strong>Methods: </strong>A cross-sectional analysis of records from 2890 Japanese community residents (mean age: 57.5 years) was conducted. LS was assessed using the stand-up test, two-step test, and 25-question Geriatric Locomotive Function Scale. Physical activity and sedentary time were assessed by self-administered questionnaires. The associations among physical activity, sedentary time, and LS were examined by logistic regression analysis stratified by age (<65 years and ≥65 years) and sex.</p><p><strong>Results: </strong>Vigorous physical activity in men aged ≥65 years, and moderate and vigorous physical activities in women aged <65 years were significantly associated with lower odds of LS. By contrast, no significant association was found between physical activity and LS in men <65 years and women ≥65 years of age. No association between light physical activity and the LS was found in either group. The association between sedentary time and LS was observed in women aged <65 years.</p><p><strong>Conclusions: </strong>Physical activity and sedentary time were associated with the LS but in an age- and sex-dependent manner. This study highlights the importance of engaging individuals in high-intensity physical activity to prevent or address LS.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"28 2","pages":"92-98"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Six-minute Walk Test Parameters by Severity of Idiopathic and Non-idiopathic Pulmonary Fibrosis.","authors":"Masashi Zenta, Kenji Tsushima, Tomohiro Hattori, Jin Kubo, Natsuko Miyamae, Minami Akama, Satoshi Kido","doi":"10.1298/ptr.E10288","DOIUrl":"10.1298/ptr.E10288","url":null,"abstract":"<p><strong>Objectives: </strong>The 6-minute walk test (6MWT) is generally used to evaluate endurance in interstitial lung disease (ILD). In ILD, treatment efficacy differs between patients with idiopathic pulmonary fibrosis (IPF) and those with non-idiopathic pulmonary fibrosis (non-IPF), and the clinical profile varies according to disease severity. This study compared 6MWT parameters by severity of illness in patients with IPF and non-IPF.</p><p><strong>Methods: </strong>The participants were hospitalized patients with ILD and either IPF (n = 20) or non-IPF (n = 25). To compare IPF and non-IPF by severity, patients were classified using the gender-age-physiology (GAP) index as having GAP stage I (i.e., mild) or GAP stage II/III (i.e., moderate to severe). The evaluation parameters were the 6-minute walk distance (6MWD), minimum percutaneous oxygen saturation (SpO<sub>2</sub>), heart rate recovery at 1 minute (HRR1) after the 6MWT, and modified Borg scale rating of perceived exertion.</p><p><strong>Results: </strong>The minimum SpO<sub>2</sub> value during exertion was significantly lower in the IPF group than in the non-IPF group (p < 0.05). Furthermore, when comparing by severity, patients with IPF and GAP stage I had a significantly lower 6MWD, HRR1, and SpO<sub>2</sub> value. In patients with GAP stage II/III, there were no significant differences in 6MWD, SpO<sub>2</sub> values, or dyspnea.</p><p><strong>Conclusions: </strong>Patients with mild IPF were more prone to hypoxemia, while in moderate-to-severe cases, we observed no significant hypoxemia- or endurance-related differences between IPF and non-IPF patients. This study highlights the importance of severity-based evaluation, particularly in guiding individualized rehabilitation and risk management for patients with IPF.</p>","PeriodicalId":74445,"journal":{"name":"Physical therapy research","volume":"28 2","pages":"122-128"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}