Physical activity and nutrition最新文献

{"title":"Vitamin C and glutathione supplementation: a review of their additive effects on exercise performance.","authors":"Eunjoo Lee, Hun-Young Park, Sung-Woo Kim, Jisu Kim, Kiwon Lim","doi":"10.20463/pan.2023.0027","DOIUrl":"10.20463/pan.2023.0027","url":null,"abstract":"<p><strong>Purpose: </strong>This review aimed to investigate the effects of vitamin C and glutathione supplementation on exercise performance.</p><p><strong>Methods: </strong>We conducted a literature search across the PubMed, Google Scholar, and Web of Science databases using the keywords vitamin C, glutathione, antioxidants, exercise, and oxidative stress.</p><p><strong>Results: </strong>The effects of vitamin C supplementation on exercise performance and oxidative stress levels are inconsistent. Glutathione, with its diverse forms of supplementation and methods, presents mixed outcomes. Vitamin C and glutathione have deeply interconnected antioxidant functions and are mutually essential to each other. Research investigating the combined intake of these two substances, which are intricately linked biochemically, and their effects on exercise performance remain largely unexplored.</p><p><strong>Conclusion: </strong>Studies on the effects of vitamin C and glutathione intake on exercise have been conducted using diverse approaches; however, the results have not been consistent. Although an additive effect is anticipated with the combined intake of vitamin C and glutathione, research on this topic is currently insufficient, and further studies are required.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"27 3","pages":"36-43"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72016351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analytical parameters to check association between load carriage system and bag packs-influenced musculoskeletal complications among school going students: a scoping review.","authors":"Mahima Guleria, Shashi Prakash Sharma, Amit Kumar","doi":"10.20463/pan.2023.0025","DOIUrl":"10.20463/pan.2023.0025","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the correlation between load-carriage systems and backpacks on musculoskeletal complications among school-going students. Additionally, the purpose was to identify research gaps and provide recommendations for future research.</p><p><strong>Methods: </strong>To conduct this study, we conducted a thorough search of five databases for literature published between January 2010 and December 2022. Our focus was on original published articles that reported musculoskeletal complications using analytical parameters or outcome measures among school-going students. Two reviewers independently extracted data for eligibility. The studies selected for the analysis focused on musculoskeletal complications and the outcome measures to report these complications.</p><p><strong>Results: </strong>A total of 3541 titles were screened; of which, 18 observational studies were included. The musculoskeletal complications identified in these studies included lower back, shoulder, and neck pain and disturbed posture. Overall, the quality of the reporting in these studies was deemed satisfactory.</p><p><strong>Conclusion: </strong>Our analysis revealed that pain and postural abnormalities were the most frequently reported complications. Hence, we recommend that future studies incorporate multiple evaluations rather than concentrating on a single symptom.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"27 3","pages":"20-26"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72016385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of exercise intervention using mobile healthcare on blood lipid level and health-related physical fitness in obese women: a randomized controlled trial.","authors":"Jae-Ho Choi, Hun-Young Park, Yerin Sun, Jisoo Seo, Eunjoo Lee, Sung-Woo Kim, Jisu Kim, Kiwon Lim","doi":"10.20463/pan.2023.0030","DOIUrl":"10.20463/pan.2023.0030","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effects of 12 weeks of non-face-to-face exercise intervention using mobile health (mHealth) on blood lipid levels and health-related physical fitness in obese women.</p><p><strong>Methods: </strong>Thirty obese women (aged: 39.40 ± 11.07 years, percent body fat: 37.05 ± 5.15%) were enrolled, and all completed the study. Non-face-to-face exercises were performed for 12 weeks using a mHealth and smart tracker (Charge 4, Fitbit, USA). Participants were randomly assigned to an experimental (EXP) or control (CON) group. The 12-week exercise program using mHealth included resistance (twice a week for 60 min), aerobics (five times a week for 50 min), and flexibility (five times a week for 10 min).</p><p><strong>Results: </strong>The results showed that high-density lipoprotein cholesterol (Post - Pre: 9.07 mg·dL-1, p &lt; 0.001) and ratio of low-density to high-density lipoprotein cholesterol (Post - Pre: -0.71 mg·dL-1, p &lt; 0.05) significantly changed during the intervention period in EXP. There were significant increases in sit-ups (Post - Pre: 7.73 numbers, p &lt; 0.001), grip strength (Post - Pre: 2.92 kg, p &lt; 0.001), and sit and reach (Post - Pre: 2.51 cm, p &lt; 0.01) in EXP.</p><p><strong>Conclusion: </strong>Non-face-to-face exercise using mHealth for 12 weeks improved blood lipid levels and health-related physical fitness; therefore, it can help improve compliance through self-monitoring and lifestyle changes by increasing physical activity.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"27 3","pages":"64-70"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72016386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical exercise-intervention can be valuable therapy for COVID-19 confinement and post-COVID-19 periods.","authors":"Yi-Sub Kwak, Kiyun Han, Jaeeun Lee, Jongnam Kim","doi":"10.20463/pan.2023.0024","DOIUrl":"10.20463/pan.2023.0024","url":null,"abstract":"<p><strong>Purpose: </strong>The COVID-19 pandemic and its transition into an endemic phase have profoundly impacted physical health, well-being, mental health, education, and various aspects of society, including the economy and social networks. Home confinement, social distancing, and physical inactivity have exacerbated numerous health issues, including obesity, diabetes mellitus, hypertension, hyperlipidemia, cardiovascular diseases, depression, and poor sleep quality. A systematic review has revealed significant findings: Regular aerobic programs (such as cycling or walking at an intensity of 60-80% of HR max for 20-60 minutes per session, repeated 2-3 times a week) have proven effective in improving both physical and mental health, as well as immune function. This type of physical activity has been shown to increase immunological markers, including lymphocytes, leukocytes, neutrophils, monocytes, and interleukin-6 (IL-6), while reducing low-grade inflammation. Therefore, in this study we aimed to assess the impact of tailored exercise interventions on the physical and mental health of COVID-19 patients. Based on the results, we can establish exercise intervention strategies to mitigate the negative health consequences during and after the COVID-19 pandemic.</p><p><strong>Methods: </strong>We conducted a search of the PubMed database from January 2020 to August 2023 using predefined search terms such as \"COVID-19 and post-COVID-19,\" \"exercise intervention and immunity,\" and \"mental health.\" By examining references, we explored the links between exercise interventions and the mental and physical health of COVID-19 patients.</p><p><strong>Results: </strong>A tailored, multifaceted exercise intervention should be developed and implemented to address the existing mental challenges and enhance mental health during both the pandemic and the post-COVID-19 periods.</p><p><strong>Conclusion: </strong>Breathing exercises and respiratory support techniques, including yoga, thoracic expansion exercises, airway clearance methods, and breathing control, are likely to be beneficial.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"27 3","pages":"17-19"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10636504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72016348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal physical activity and the gut microbiota of pregnant women: results from a preliminary investigation.","authors":"Sara Santarossa,&nbsp;Alexandra R Sitarik,&nbsp;Andrea E Cassidy-Bushrow,&nbsp;Sarah S Comstock","doi":"10.20463/pan.2023.0011","DOIUrl":"https://doi.org/10.20463/pan.2023.0011","url":null,"abstract":"[Purpose] To determine whether physical activity (PA), specifically meeting the recommended 150 minutes of moderate-intensity PA per week, is associated with gut microbiota composition in pregnant women. [Methods] In an ongoing birth cohort study, questions from the Behavioral Risk Factor Surveillance System, which provides data on PA variables, were used to determine whether pregnant women met or exceeded the PA recommendations. To profile the composition of gut bacterial microbiota, 16S rRNA sequencing was performed on stool samples obtained from pregnant women. Differences in alpha diversity metrics (richness, Pielou’s evenness, and Shannon’s diversity) according to PA were determined using linear regression, whereas beta diversity relationships (Canberra and Bray-Curtis) were assessed using Permutational multivariate analysis of variance (PERMANOVA). Differences in relative taxon abundance were determined using DESeq2. [Results] The complete analytical sample included 23 women that were evaluated for both PA and 16S rRNA sequencing data (median age [Q1; Q3] = 30.5 [26.6; 34.0] years; 17.4% Black), and 11 (47.8%) met or exceeded the PA recommendations. Meeting or exceeding the PA recommendations during pregnancy was not associated with gut microbiota richness, evenness, or diversity, but it was related to distinct bacterial composition using both Canberra (p = 0.005) and Bray-Curtis (p = 0.022) distances. Significantly lower abundances of Bacteroidales, Bifidobacteriaceae, Lactobacillaceae, and Streptococcaceae were observed in women who met or exceeded the PA recommendations (all false discovery rates adjusted, p < 0.02). [Conclusion] Pregnant women who met or exceeded the PA recommendations showed altered gut microbiota composition. This study forms the basis for future studies on the impact of PA on gut microbiota during pregnancy.","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"27 2","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/07/ed/pan-2023-0011.PMC10440177.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10046755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of exercise intensity on the reactive astrocyte polarization in the medial prefrontal cortex.","authors":"Su-Ju Eo,&nbsp;Yea-Hyun Leem","doi":"10.20463/pan.2023.0014","DOIUrl":"https://doi.org/10.20463/pan.2023.0014","url":null,"abstract":"<p><strong>Purpose: </strong>Physical exercise contributes to neuroplasticity by promoting cognitive functions, such as learning and memory. The astrocytic phenotype is closely associated with synaptic plasticity. This study aimed to determine whether astrocyte polarization and synaptic alterations in the medial prefrontal cortex (mPFC) are affected differently by high- and moderate-intensity exercise.</p><p><strong>Methods: </strong>Mice were subjected to moderate-(MIE) and high-intensity treadmill running (HIE). Memory capacity was assessed using the novel object recognition and modified Y-maze tests. For immunohistochemistry, c-Fos-positive cells were counted in the mPFC. Using western blot analysis, astrocyte phenotype markers were quantified in whole-cell lysates, and synaptic molecules were determined in the synaptosomal fraction.</p><p><strong>Results: </strong>Exercise lengthened the approach time to novel objects regardless of intensity in the NOR test, whereas MIE only improved spatial memory. Exercise induced c-Fos expression in the anterior cingulate cortex (ACC) and c-Fos-positive cells were higher in MIE than in HIE in the ACC area. In the prelimbic/infralimbic cortex region, the number of c-Fos-positive cells were enhanced in MIE and decreased in HIE mice. The A1 astrocyte marker (C3) was increased in HIE mice, while the A2 astrocyte markers were enhanced in exercised mice, regardless of the intensity. In the synaptosomal fraction, synaptic proteins were elevated by exercise regardless of intensity.</p><p><strong>Conclusion: </strong>These results suggest that exercise intensity affects neuronal plasticity by modulating the reactive state of astrocytes in the mPFC.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"27 2","pages":"19-24"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/82/68/pan-2023-0014.PMC10440185.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10048786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Running exercise and food restriction affect bone chemical properties in young female rats.","authors":"Yuki Aikawa,&nbsp;Yuich Noma,&nbsp;Umon Agata,&nbsp;Yuya Kakutani,&nbsp;Satoshi Hattori,&nbsp;Hitomi Ogata,&nbsp;Ken Kiyono,&nbsp;Naomi Omi","doi":"10.20463/pan.2023.0019","DOIUrl":"https://doi.org/10.20463/pan.2023.0019","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the effects of a combination of running and food restriction on the chemical properties of the bone in young female rats using Raman spectroscopy. Furthermore, we investigated whether the chemical property parameters correlated with the bone-breaking strength.</p><p><strong>Methods: </strong>Female Sprague-Dawley rats (7 weeks old) were randomly divided into four groups: sedentary and ad libitum feeding (SED, n = 8), voluntary running exercise and ad libitum feeding (EX, n = 8), sedentary and 30% food-restricted (SED-FR, n = 8), and voluntary running exercise and 30% food-restricted (EXFR, n = 8). The experiment was conducted for a period of 12 weeks. Four parameters measured by Raman spectroscopy were used to evaluate the bone chemical quality.</p><p><strong>Results: </strong>Exercise and restriction had significant interactions on the mineral to matrix ratio. The mineral- to-matrix ratio in the SED-FR group was significantly higher than that in the SED group and significantly lower in the EX-FR group than that in the SED-FR group. Running exercise had significant effects on increasing the crystallinity and carbonate-to-phosphate ratio. In the ad libitum intake condition, there were significant positive correlations between breaking energy and crystallinity (r = 0.593) and between breaking energy and carbonate-to-phosphate ratio (r = 0.854).</p><p><strong>Conclusion: </strong>Our findings show that running exercise and food restriction, alone or in combination, affect the chemical properties of bone. Furthermore, under ad libitum intake conditions, positive correlations were found between the breaking energy and crystallinity, or carbonate-to-phosphate ratio.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"27 2","pages":"62-69"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/16/d3/pan-2023-0019.PMC10440179.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10048785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exogenous lactate intake immediately after endurance exercise increases time to exhaustion in VO2max measurements in mice.","authors":"Sunghwan Kyun,&nbsp;Jisu Kim,&nbsp;Deunsol Hwang,&nbsp;Inkwon Jang,&nbsp;Jeehee Choi,&nbsp;Jongwon Kim,&nbsp;Won-Sang Jung,&nbsp;Hyejung Hwang,&nbsp;Sung-Woo Kim,&nbsp;Jeeyoung Kim,&nbsp;Kyunghwa Jung,&nbsp;Jisoo Seo,&nbsp;Yerin Sun,&nbsp;Hun-Young Park,&nbsp;Kiwon Lim","doi":"10.20463/pan.2023.0013","DOIUrl":"https://doi.org/10.20463/pan.2023.0013","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study was to investigate the effects of 4 weeks of lactate intake immediately after endurance exercise on maximal oxygen uptake (VO2max) in exercise performance.</p><p><strong>Methods: </strong>Seven-week-old mice from the Institute of Cancer Research (ICR) were randomly divided into four groups: vehicle intake (SE/CON), lactate intake (SE/LAC), endurance exercise with vehicle intake (EX/ CON), and lactate intake with endurance exercise (EX/ LAC). Mice were subjected to 60-70% VO2max endurance exercise with or without oral lactate intake 5 days/ week for 4 weeks. VO2max measurements (VO2max, time to exhaustion (TTE), respiratory exchange rate, fat oxidation, and carbohydrate oxidation) were recorded at the end of the study period. After 48 h of VO2max measurement, the mice were sacrificed, and three different abdominal fat samples (epididymal, perirenal, and mesenteric) were collected.</p><p><strong>Results: </strong>Body weight and abdominal fat mass did not differ between the groups. When measuring VO2max, endurance exercise raised VO2max, and lactate intake after endurance exercise increased TTE. The change in energy substrate utilization during VO2max measurement demonstrated that although the respiratory exchange rate and fat oxidation were enhanced by lactate intake, there were no synergistic effects of lactate intake and endurance exercise.</p><p><strong>Conclusion: </strong>Lactate intake immediately after endurance exercises can improve exercise performance, indicating the benefit of long-term exogenous lactate intake as an exercise supplement.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"27 2","pages":"13-18"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/8d/pan-2023-0013.PMC10440182.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10048787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of curcumin supplementation on inflammatory status and muscle damage in competitive female soccer players: a placebo-controlled, singleblind, nonrandomized, crossover pilot study.","authors":"Youngju Choi,&nbsp;Song-Gyu Ra,&nbsp;Takahiko Nishijima,&nbsp;Seiji Maeda","doi":"10.20463/pan.2023.0016","DOIUrl":"https://doi.org/10.20463/pan.2023.0016","url":null,"abstract":"<p><strong>Purpose: </strong>Curcumin, a major component of turmeric, has anti-inflammatory and antioxidative properties, which are associated with protective effects against muscle damage. This study examined the effects of dietary curcumin on inflammation and muscle damage in female competitive soccer players.</p><p><strong>Methods: </strong>A single-blinded, placebo-controlled, nonrandomized, crossover pilot study was conducted. Six competitive female soccer players (20.0 ± 2.0 yearsold) who participated in a 2-week preseason training program were assigned to two conditions: placebo and curcumin. The participants ingested a placebo or curcumin dosage (270 mg/day) during 2 weeks of preseason training, with 1 week of washout. Fasting blood samples were collected under resting conditions before (day 0) and after (day 15) the training period to examine changes in the concentration of interleukin 6 (IL-6), an inflammatory marker, and indices reflective of muscle damage.</p><p><strong>Results: </strong>Curcumin decreased the concentration of IL-6 released (mean decrease, -30.2 ± 28.1%), whereas no decrease was observed in the placebo condition (13.4 ± 17.4%). Changes in plasma IL-6 concentrations were significantly greater in the curcumin condition than in the placebo condition (p &lt; 0.05). However, curcumin supplementation had no significant effects on muscle damage indices.</p><p><strong>Conclusion: </strong>The present study shows that curcumin supplementation could attenuate inflammation, as indicated by IL-6 concentrations, in competitive female soccer players during the training period.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"27 2","pages":"34-38"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b1/5f/pan-2023-0016.PMC10440175.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10048790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-obesity effects of Camellia (Camellia oleifera Abel) oil treatment on high-fat diet-induced obesity in C57BL/6J mice.","authors":"Ramakrishna Chilakala,&nbsp;Hyeon Jeong Moon,&nbsp;Kiwoong Kim,&nbsp;Soyoung Yang,&nbsp;Sun Hee Cheong","doi":"10.20463/pan.2023.0018","DOIUrl":"https://doi.org/10.20463/pan.2023.0018","url":null,"abstract":"<p><strong>Purpose: </strong>In the current study, we investigated the effects of camellia oil and camellia oil infused with herbs (Camellia oleifera Abel) on obesity in obese mice fed a high-fat diet (HFD).</p><p><strong>Methods: </strong>The antioxidant activity of camellia oil in scavenging free radicals was investigated. Additionally, body and organ weight changes, serum and liver marker parameters, antioxidant enzyme activities, liver and epididymal fat histology, protein and gene expression associated with lipogenesis and hyperglycemia effect on adenosine monophosphate-activated protein kinase (AMPK) phosphorylation, were examined in HFD-induced obese mice.</p><p><strong>Results: </strong>The hepatic steatosis and epididymal fat were significantly reduced by the oral administration of camellia oil and herb-infused camellia oil. Moreover, hepatic and serum marker parameters such as total cholesterol, insulin, triglycerides, tumor necrosis factor-α, adiponectin, thiobarbituric acid reactive substances, aspartate aminotransferase, and alanine transaminase were beneficially impacted. Additionally, the activity of antioxidant enzymes also increased. Camellia oil and herb-infused camellia oil treatments reduced the expression of genes linked to hyperglycemia and lipogenesis via activation of AMPK phosphorylation.</p><p><strong>Conclusion: </strong>For many people, exercise poses an obstacle in the daily routine due to lack of ease, difficulty in maintaining consistency, and hard work. Camellia oil combined with herbs has anti-obesity and antihyperglycemic effects. These findings indicate that treatment with herb-infused camellia oil is most beneficial for elderly individuals who do not prefer frequent exercise.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"27 2","pages":"50-61"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/30/pan-2023-0018.PMC10440180.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10048788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}