Deunsol Hwang, Sunghwan Kyun, Inkwon Jang, Taeho Kim, Nayeon Kim, Jungyong Lee, Hun-Young Park, Sung-Woo Kim, Insu Kwon, Ahjin Kim, Hangsu Cho, Taehyeon Park, Soohan Jung, Jisu Kim, Kiwon Lim
{"title":"A complementary amino acid formulation enhances exercise-induced skeletal muscle remodeling during resistance training.","authors":"Deunsol Hwang, Sunghwan Kyun, Inkwon Jang, Taeho Kim, Nayeon Kim, Jungyong Lee, Hun-Young Park, Sung-Woo Kim, Insu Kwon, Ahjin Kim, Hangsu Cho, Taehyeon Park, Soohan Jung, Jisu Kim, Kiwon Lim","doi":"10.20463/pan.2026.0047","DOIUrl":"10.20463/pan.2026.0047","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated whether a five-amino-acid formulation integrating complementary anabolic, metabolic, and redox-supporting functions enhances skeletal muscle remodeling during resistance training.</p><p><strong>Methods: </strong>Male C57BL/6N mice were assigned to eight groups receiving vehicle, leucine (300 mg/kg), or amino acid formulation (150-1,500 mg/kg). All mice completed four weeks of ladder resistance training, while the assigned supplements were administered orally once daily. Muscle function, body composition, gastrocnemius fiber cross-sectional area (CSA), anabolic and metabolic signaling proteins, the muscular NAD+/NADH ratio, and circulating markers of muscle damage, inflammation, and glutathione status were assessed.</p><p><strong>Results: </strong>The formulation improved grip strength at doses of 600-1,500 mg/kg and increased gastrocnemius fiber CSA at 1,200 and 1,500 mg/kg compared with vehicle (p < 0.05), without affecting body weight, food intake, body composition, or absolute muscle mass. It also enhanced AKT-related signaling and increased the expression of PGC-1α, citrate synthase, and UCP3. Several anabolic and mitochondrial protein responses exceeded those observed with leucine alone. The NAD+/NADH ratio increased at doses of 150, 900, and 1,200 mg/kg, with the greatest response observed at 900 mg/kg. The formulation reduced circulating TNF-α at a dose of 1,200 mg/kg, produced a dose-related decrease in CKM that approached statistical significance at 1,500 mg/kg, and most prominently increased total and reduced glutathione levels at 900 mg/kg.</p><p><strong>Conclusion: </strong>The complementary amino acid formulation enhanced functional, structural, anabolic, metabolic, and redox adaptations during resistance training. These coordinated effects support its potential as a nutritional strategy for improving skeletal muscle quality during chronic resistance exercise.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"30 3","pages":"124-138"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Compositional associations of 24-hour movement behaviors with metabolic syndrome in Korean older adults: a nationwide cross-sectional study using KNHANES 2022-2024.","authors":"Ahn Hana, Won-Sang Jung","doi":"10.20463/pan.2026.0035","DOIUrl":"10.20463/pan.2026.0035","url":null,"abstract":"<p><strong>Purpose: </strong>Movement behaviors over 24 hours-sleep, sedentary time, and physical activity-are temporally interdependent, but most Korean studies in older adults have analyzed them in isolation. We examined how the 24-hour movement composition relates to metabolic syndrome (MetS) in adults aged ≥ 65 years.</p><p><strong>Methods: </strong>We pooled data from the 9th Korea National Health and Nutrition Examination Survey (KNHANES; 2022-2024) and analyzed 4,316 community-dwelling older adults. Daily time in sleep, sedentary behavior, light physical activity (LIPA), and moderate-to-vigorous physical activity (MVPA) was rescaled to 1,440 min/day. Isometric log-ratio (ilr) coordinates were entered into weighted logistic regression that accounted for the complex survey design, and 30-min isotemporal substitutions were estimated.</p><p><strong>Results: </strong>Weighted MetS prevalence was 40.4%. Greater relative time in MVPA (ilr1) and LIPA (ilr2) was inversely associated with MetS (OR 0.93, 95% CI 0.89-0.96; OR 0.80, 0.70-0.91), whereas a higher sedentary-to-sleep ratio (ilr3) showed a positive association (OR 1.28, 1.02-1.62). Reallocating 30 min from sedentary time to MVPA was associated with about 13% lower predicted odds of MetS (OR 0.87, 0.82-0.93), and even a shift to LIPA showed a small but significant association (OR 0.97, 0.96-0.98). Sex-stratified analyses showed broadly consistent patterns in men and women.</p><p><strong>Conclusion: </strong>In Korean older adults, replacing sedentary time with any form of activity-especially MVPA- was associated with lower predicted odds of MetS, supporting a 24-hour movement perspective for metabolic-health promotion.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"30 3","pages":"16-23"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Latent profiles of body composition in older adults with hypertension: associations with physical fitness and differences in blood pressure and fasting plasma glucose.","authors":"Jae-Hoon Lee, Jaehee Lee, Min-Seong Ha","doi":"10.20463/pan.2026.0049","DOIUrl":"10.20463/pan.2026.0049","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to identify the body composition profiles of older adults with hypertension and examine their associations with physical fitness and cardiometabolic characteristics.</p><p><strong>Methods: </strong>This cross-sectional study included 491 community-dwelling older adults with hypertension. Latent profile analysis was conducted using eight body composition indicators. Associations between age, physical fitness components, and profile membership were examined using multinomial logistic regression with a three-step approach. Systolic blood pressure, diastolic blood pressure, and fasting plasma glucose levels were compared across profiles using one-way analysis of variance.</p><p><strong>Results: </strong>Four profiles were identified: low muscle mass, balanced, high adiposity, and high muscle/low fat ratio. Handgrip strength, balance, and flexibility were significantly associated with profile membership, whereas age and aerobic endurance were not. The high adiposity profile had significantly higher systolic blood pressure than the low muscle and high muscle/low fat profiles, and higher diastolic blood pressure than the low muscle profile. The high muscle/low fat profile was associated with significantly lower fasting plasma glucose levels than the low muscle and high adiposity profiles.</p><p><strong>Conclusion: </strong>Distinct body composition profiles in older adults with hypertension were associated with differences in physical fitness and cardiometabolic characteristics. These findings support the value of a person-centered approach that integrates body composition and physical fitness.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"30 3","pages":"151-161"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Integrative ALS therapy: gene targeted therapy by base editing and potential exercise rehabilitation as synergistic strategies for functional recovery.","authors":"Kwangjun Lee, Taejin Kwak, Wonil Park","doi":"10.20463/pan.2026.0045","DOIUrl":"10.20463/pan.2026.0045","url":null,"abstract":"<p><strong>Purpose: </strong>A key pathological hallmark of amyotrophic lateral sclerosis (ALS) is transactive response DNA-binding protein 43 (TDP-43, encoded by TARDBP) proteinopathy. Mutations in TARDBP and cellular stress can drive nuclear clearance and cytoplasmic aggregation of TDP-43. TDP-43 is an essential nuclear RNA-binding protein that regulates RNA metabolism, and cytoplasmic TDP-43 aggregation leads to aberrant splicing of essential neuronal transcripts including stathmin-2 (STMN2) and unc-13 homolog A (UNC13A). Dysregulated RNA splicing causes cryptic exon (CE) inclusion in STMN2 and UNC13A mRNA, resulting in non-functional proteins and disruption of axonal regeneration and synaptic integrity. Splice-switching antisense oligonucleotides and gene-editing platforms can correct STMN2 and UNC13A mis-splicing defects. However, restoring STMN2 and UNC13A expression alone is not sufficient to regenerate neuromuscular junctions or reverse skeletal muscle atrophy, both of which are crucial for functional recovery in patients with ALS.</p><p><strong>Methods: </strong>We reviewed gene-targeted treatment strategies and rehabilitative mechanisms that inhibit ALS progression and reverse neuromuscular degeneration by analyzing databases, including Google Scholar, PubMed, and ScienceDirect. We proposed a dual-modality therapeutic approach integrating base-editing-mediated gene therapy with exercise-based rehabilitation.</p><p><strong>Results: </strong>Antisense oligonucleotides and genome editing can restore transcript fidelity by preventing cryptic exons inclusion in STMN2 and UNC13A, thereby stabilizing neuronal function. Gene-targeted therapies halt ALS progression; however, these treatments alone are insufficient to reverse neuromuscular degeneration or achieve functional recovery needed for patients with ALS to return to daily life.</p><p><strong>Conclusion: </strong>Integrated rehabilitation is a crucial step in gene-targeted therapy for ALS. This strategy halts disease progression and restores neuromuscular function, thereby improving the lifespan and quality of life of patients with ALS.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"30 3","pages":"97-113"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of plyometric training combined with tDCS on lower-limb muscle activation and cardiopulmonary function in male amateur soccer players: a randomized controlled trial.","authors":"Jeong-Il Kang, Dae-Joong Yang, Hyeong-Seok Lee","doi":"10.20463/pan.2026.0040","DOIUrl":"10.20463/pan.2026.0040","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the effects of combining transcranial direct current stimulation (tDCS) with plyometric training on lower-limb muscle activation and cardiorespiratory function in male amateur soccer players.</p><p><strong>Methods: </strong>Thirty male amateur soccer players were randomly assigned to an experimental group (n = 15) or a control group (n = 15). The experimental group performed plyometric training combined with transcranial direct current stimulation (tDCS), whereas the control group performed plyometric training with sham stimulation. The intervention was conducted three times per week for four weeks. Lower-limb muscle activation (RF, VL, VM, and GCM) and cardiorespiratory function (MIP, MIFR, VO2max, Wmax, and MEC) were assessed before and after the intervention. Data were analyzed using a two-way mixed-design ANOVA.</p><p><strong>Results: </strong>Both groups showed significant within-group improvements in muscle activation and cardiorespiratory variables (p < 0.05). However, the experimental group demonstrated significantly greater enhancements in RF, VL, VM, and GCM activation compared with the control group (p < 0.05). Between-group comparisons also revealed superior improvements in MIFR and Wmax in the experimental group (p < 0.05), while VO2max increased significantly over time in both groups without between-group differences. A two-way mixed-design ANOVA indicated significant group × time interactions for muscle activation and selected cardiorespiratory indices (p < 0.05), supporting enhanced neuromuscular and physiological adaptations in the experimental group.</p><p><strong>Conclusion: </strong>Combining tDCS with plyometric training enhanced lower-limb muscle activation and cardiorespiratory function more effectively than plyometric training alone in amateur soccer players.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"30 3","pages":"54-63"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149171650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of morning versus evening high-intensity exercise on electroencephalographic and autonomic responses in middle-aged women.","authors":"Jae-Myun Ko, Wi-Young So, Jae-Hyun Jung","doi":"10.20463/pan.2026.0036","DOIUrl":"10.20463/pan.2026.0036","url":null,"abstract":"<p><strong>Purpose: </strong>The time of day at which exercise is performed influences physiological responses and performance, and thus its health benefits. This study investigated whether electroencephalographic (EEG) and autonomic nervous system responses to morning versus evening exercise differed in middle-aged women.</p><p><strong>Methods: </strong>Thirty women aged 50-60 years were randomly assigned to a morning or evening exercise group. Participants were asked to sleep for seven to eight hours before testing. The morning group exercised at 6:00 am and the evening group at 6:00 pm. EEG-derived indices included the theta-to-beta ratio (TBR) and spectral edge frequency at 90% (SEF-90). Photoplethysmography-derived autonomic indices comprised the HRV index and HRV-derived sympathetic-related and parasympathetic-related indices, measured at rest before and immediately after exercise. Data were analyzed using a two-way mixed-design analysis of variance. For significant interactions, simple effects and change-score analyses were performed.</p><p><strong>Results: </strong>TBR and SEF-90 showed significant group × time interactions, with greater changes from pre- to post-exercise in the morning group. TBR increased and SEF-90 decreased following exercise in both groups, with greater changes in the morning group. The HRV index showed only a significant main effect of time. However, HRV-derived sympathetic-related and parasympathetic-related indices demonstrated significant group × time interactions, with greater autonomic responses in the morning group, as measured by change scores.</p><p><strong>Conclusion: </strong>EEG- and HRV-derived neurophysiological response patterns to high-intensity exercise may vary with exercise timing. Morning high-intensity exercise may elicit greater neurophysiological responses than evening exercise, highlighting the importance of exercise timing in training strategies and recovery.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"30 3","pages":"24-31"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149171891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of a weighted-vest aerobic dance intervention for enhancing lower extremity strength and mobility in older adults: a randomized controlled trial.","authors":"Sasithorn Sukjit, Bhakbhum Choktaweepanich, Worrawut Thuwakum","doi":"10.20463/pan.2026.0042","DOIUrl":"10.20463/pan.2026.0042","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the effectiveness of an 8-week aerobic dance program combined with a weighted vest on functional fitness, body composition, and bone mineral density (BMD) in postmenopausal women with low bone mass.</p><p><strong>Methods: </strong>Fifty-seven participants (60-80 years) were randomized to perform 50-minute aerobic dance sessions (3 days/week for 8 weeks) either alone (AD, n = 28) or while wearing a 7% body mass weighted vest (AD + WV, n = 29). The outcomes included the Senior Fitness Test, body composition, BMD, and resting blood pressure.</p><p><strong>Results: </strong>After the 8-week intervention, the AD + WV group demonstrated a significantly greater increase in lower body strength (30-second chair stand), with a 38.1% increase, compared to an 11.3% increase in the AD group (interaction p = 0.002). Dynamic mobility (Timed Up and Go) showed no significant time (p = 0.477), group (p = 0.327), or interaction (p = 0.546) effects. Additionally, both groups showed equivalent reductions in resting systolic and diastolic blood pressure, which were statistically significant (p < 0.05). There were no significant changes in total muscle mass or BMD in either group (p > 0.05), and no training-related injuries were observed.</p><p><strong>Conclusion: </strong>Adding a 7% weighted vest to aerobic dance safely and effectively enhances lower body strength in older women with low bone mass. The absence of short-term structural changes suggests improvements may stem from multiple mechanisms, including neuromuscular adaptations, warranting further investigation. This intervention may represent an adjunctive strategy for improving functional capacity related to fall risk, though this potential benefit requires confirmation in future studies.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"30 3","pages":"73-80"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ye-Jun Han, Hyun Ahn, Sea-Hyun Bae, Kyung-Yoon Kim
{"title":"Effects of keiser-assisted Nordic hamstring curl training on hamstring flexibility, mechanical properties, and pitching performance in high school baseball pitchers.","authors":"Ye-Jun Han, Hyun Ahn, Sea-Hyun Bae, Kyung-Yoon Kim","doi":"10.20463/pan.2026.0038","DOIUrl":"10.20463/pan.2026.0038","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the effects of 10-week Keiser-assisted Nordic hamstring curl (NHC) training on the mechanical properties, muscle strength, and flexibility of the hamstrings, as well as shoulder range of motion (ROM) and pitching performance in high school baseball pitchers.</p><p><strong>Methods: </strong>Sixteen high school baseball pitchers performed Keiser assisted NHC training for 10 weeks. The pre- and post-training measurements included the mechanical properties of the hamstrings (muscle tone, stiffness, elasticity, creep) measured using MyotonPRO, isometric muscle strength, trunk and shoulder ROM, and pitching performance (velocity and spin rate).</p><p><strong>Results: </strong>After training, hamstring muscle tone, stiffness, and elasticity significantly decreased (p < 0.01), whereas creep and isometric strength significantly improved (p < 0 0.001) (effect size dz = 0.84-2.90). Additionally, the trunk flexion range significantly increased (p < 0.001, dz = 2.12), and the glenohumeral internal rotation deficit in the throwing shoulder significantly improved (p < 0.05). The pitching velocity (p < 0.001, dz = 2.61) and spin rate (p < 0.01, dz = 0.89) significantly increased.</p><p><strong>Conclusion: </strong>Keiser-assisted NHC training improved hamstring mechanical efficiency, isometric strength, and trunk flexibility, with concurrent gains in pitching velocity and spin rate. As this was a single-group pre-post study without a control group, these findings require confirmation through controlled trials.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"30 3","pages":"41-47"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyejung Shin, Nur Afiqah Binti Zulkifli, Byunggul Lim, Wook Song
{"title":"Effects of Kinect-based mixed-reality exercise and deep-sea water consumption on metabolic syndrome: a randomized controlled trial.","authors":"Hyejung Shin, Nur Afiqah Binti Zulkifli, Byunggul Lim, Wook Song","doi":"10.20463/pan.2026.0046","DOIUrl":"10.20463/pan.2026.0046","url":null,"abstract":"<p><strong>Purpose: </strong>The increasing prevalence of metabolic syndrome poses significant health risks, particularly for cardiovascular diseases and type 2 diabetes. Exercise interventions have shown promise in improving the components of metabolic syndrome, including blood pressure, lipid profiles, and glucose metabolism. Kinect-based mixed-reality exercise provides real-time feedback and personalized guidance, making it suitable for unsupervised training. Deep-sea water has beneficial effects on lipid metabolism and insulin sensitivity. However, the effects of Kinect-based mixed-reality exercise and deep-sea water on metabolic syndrome remain unclear.</p><p><strong>Methods: </strong>Fifty-six participants aged 30-65 years with a diagnosis of metabolic syndrome were randomly assigned to four groups for an 8-week intervention: control (CG), deep-sea water consumption (WG), Kinect-based mixed-reality exercise (EG), and combined deep-sea water consumption and Kinect-based mixed-reality exercise (WEG). The intervention comprised a 40-min Kinect-based mixed-reality circuit exercise three times per week and daily consumption of 440 mL of deep-sea water. The measurements included blood pressure, body composition, blood profiles, quality of life, physical activity, diet recall, and the metabolic syndrome score.</p><p><strong>Results: </strong>Forty-eight participants completed the study, demonstrating high compliance with the EG (98.4%) and WG (99.2%). Waist circumference significantly decreased in all intervention groups (WG, p = 0.002; EG, p < 0.0001; WEG, p < 0.0001), with a significant difference between CG and EG (p = 0.020). The metabolic syndrome component score decreased significantly in the EG (p = 0.004) and WEG (p = 0.002) groups, falling below the diagnostic threshold for metabolic syndrome.</p><p><strong>Conclusion: </strong>These findings indicate the potential benefits of combining deep-sea water consumption and Kinect-based mixed-reality exercise in metabolic syndrome management.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"30 3","pages":"114-123"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniela Presta, Emma H Chen, Kate Kraemer, Andreas Bergdahl
{"title":"The effects of blood flow restriction training during low intensity online resistance training with older adults.","authors":"Daniela Presta, Emma H Chen, Kate Kraemer, Andreas Bergdahl","doi":"10.20463/pan.2026.0033","DOIUrl":"10.20463/pan.2026.0033","url":null,"abstract":"<p><strong>Purpose: </strong>Blood flow restriction (BFR) training involves limiting blood flow to specific areas, enabling low-intensity exercise to mimic high-intensity workouts. This study explored the effectiveness of combining BFR with online exercise classes to improve strength and functionality in older adults.</p><p><strong>Methods: </strong>Over ten weeks, men and women, N = 41 with 22 BFR and 19 control (CON), (mean age = 70 ± 6.2) participated in Zoom sessions twice a week. Strength in the hamstrings and quadriceps was assessed using a dynamometer, while functionality was tested with the 30-second sit-to-stand, 8-foot timed upand-go, and 30-second calf raise tests.</p><p><strong>Results: </strong>Both the BFR and CON groups showed improvements in muscle strength and lower extremity functionality. However, the BFR group achieved greater gains, mainly in functional performance.</p><p><strong>Conclusion: </strong>The observed preliminary evidence suggests that BFR augment the effectiveness of low-intensity exercise by providing an additional physiological stimulus without increasing mechanical load. This study highlights a novel, accessible, and practical strategy for improving functional mobility in aging populations, particularly for individuals who may be unable or unwilling to engage in higher-intensity training. ClinicalTrials.gov: NCT06724393.</p>","PeriodicalId":74444,"journal":{"name":"Physical activity and nutrition","volume":"30 3","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149168863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}