Pharmacognosy reviews最新文献

{"title":"Medicinal Plants with Potent Anti-inflammatory and Anti-arthritic Properties found in Eastern Parts of the Himalaya: An Ethnomedicinal Review","authors":"Bapan Banik, Sanjoy Das, M. K. Das","doi":"10.5530/PHREV.2020.14.16","DOIUrl":"https://doi.org/10.5530/PHREV.2020.14.16","url":null,"abstract":"Copyright © 2020 Phcog.Net. This is an openaccess article distributed under the terms of the Creative Commons Attribution 4.0 International license. ABSTRACT Since ancient times, medicinal plants performing a very essential role as a source of medicine and their medicinal properties have been well documented in the various traditional systems of medicine including Indian, Chinese and Korean medicines for the management of chronic inflammatory disorders. Arthritis is one of the harmful chronic inflammatory diseases and its pain vastly affects millions of people throughout the world. The inflammatory process of arthritis can stride very promptly causing swelling and destroying bone or cartilage cross the joints by various inflammatory mediators. Presently most commonly prescribed medication for the management of inflammation or arthritic pain is the NSAIDs, DMARDs and corticosteroids. Their prolonged use may cause a high spectrum of toxic effects. Hence, there is a demanding need to develop alternative therapeutic agents with minimum toxic effects. The Eastern Himalayan region is richly furnished with multifarious medicinal plants with potent anti-inflammatory and/ or anti-arthritic properties that have been traditionally used by the local people. Few studies have been convened in Himalayan medicinal plants to validate their medicinal values. Thus, from the knowledge of traditional medicine and research on plant materials, one might be able to discover newer and cost-effective drugs for treating diverse forms of inflammation. This review highlights the medicinal plants from the Eastern Himalayan region which showed promising therapeutic activity against inflammatory diseases as well as novel formulation approaches of these medicinal plants.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86154406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypoglycaemic Property of Yacon (Smallanthus sonchifolius (Poepp. and Hendl.) H. Robinson): A Review","authors":"Neyder Contreras-Puentes, Antistio Alvíz-Amador","doi":"10.5530/PHREV.2020.14.7","DOIUrl":"https://doi.org/10.5530/PHREV.2020.14.7","url":null,"abstract":"Cite this article: Contreras-Puentes N, Alvíz-Amador A. Hypoglycaemic Property of Yacon (Smallanthus sonchifolius (Poepp. and Hendl.) H. Robinson): A Review. Pharmacog Rev. 2020;14(27):37-44. ABSTRACT Diabetes is currently a chronically more important disease due to the high rates affecting 8.5% of the world population. The need to look for natural sources as alternative elements for the treatment of this type of diseases is of greater impetus, in which the discovery and research of new natural products has been strengthened. Currently, in integrative therapies it is common to use natural elements such as yacon, due to its extensive pharmacological properties explored as anti-oxidants, prebiotics, anti-cancer, normolipemiants, cytoprotective and mainly for its greater use as a hypoglycaemic element. Thus, in this work was carried out a systematic review of the most important scientific reports on the role of yacon in hypoglycaemic activity; likewise, to develop a conceptual expansion of the metabolites and chemical composition reported that relate to their activity in the regulation of glycaemia levels and finally relating possible mechanisms related between the presence of said metabolites and hypoglycaemic activity.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78478657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leea macrophylla: A Review on Ethanobotanical Uses, Phytochemistry and Pharmacological Action","authors":"M. Malik, G. Upadhyay","doi":"10.5530/PHREV.2020.14.6","DOIUrl":"https://doi.org/10.5530/PHREV.2020.14.6","url":null,"abstract":"Cite this article: Malik M, Leea macrophylla: A Review on Ethanobotanical Uses, Phytochemistry and Pharmacological Action. Pharmacog Rev. 2020;14(27):33-6. ABSTRACT Leea macrophylla Roxb. ex hornis a perennial shrub that belongs to the Leeaceae family. The plant has widely been used as a traditional medicine for long time. It is rich in phytochemical constituents such as alkaloids, steroids, glycosides, saponins, carbohydrates, proteins and tannins. Moreover, it has significant therapeutic effects and various preclinical studies have been conducted on the plant to elucidate its pharmacological response which includes antidiabetic, hepatoprotective, antioxidant, antimicrobial, anti-inflammatory, antiurolithiatic and anti-nociceptive, cytotoxic, antithrombotic, neuroprotective, wound healing and cardiotonic activity . The scientific validation is essential for the acceptance of medicinal plants as therapeutic agents against several disorders. Hence, the traditional uses, phytochemical constituents, medicinal significance and pharmacological effects of the plant are discussed in this review.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88622692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroprotective Effects of Guanosine Supplementation in Experimental Models: A Systematic Review","authors":"Ana Paula de Carvalho Bezerra, Elayne Cristina Gurgel Andrade Pedrosa, I. M. Costa, J. Cavalcanti, L. C. Oliveira, Dayane Pessoa de Araújo, Amália Cinthia Menezes Rêgo, I. Araújo-Filho, Francisco Irochima Pinheiro, F. Guzen","doi":"10.5530/PHREV.2020.14.10","DOIUrl":"https://doi.org/10.5530/PHREV.2020.14.10","url":null,"abstract":"Cite this article: Bezerra APDC, Pedrosa ECGA, Costa IMD, Cavalcanti JRLDP, Oliveira LCD, Araújo DPD, Rego ACMD, Filho IA, Pinheiro FI, Guzen FP. Neuroprotective Effects of Guanosine Supplementation in Experimental Models: A Systematic Review. Pharmacog Rev. 2019;13(26):x-x. ABSTRACT Guanosine (GUO) is an endogenous guanine nucleoside to which several neuroprotective and neurotrophic effects have been attributed in experimental in vitro and/or in vivo models of central nervous system (CNS) diseases, including ischemic stroke, Alzheimer’s, Parkinson’s disease, spinal cord injury, nociception and depression. The objective of this work is to systematically review the neuroprotective effects of guanosine in experimental models in the CNS. The research was conducted through PubMed, Science direct, Scopus, Cochrane Library and SciELO (Scientific Electronic Library Online) and databases, where a number of relevant articles were found. Central nervous system (CNS) astrocytes release guanosine extracellularly, that has trophic effects. In the CNS, extracellular guanosine (GUO) stimulates mitosis, the synthesis of trophic factors and cell differentiation, including neuritogenesis, is neuroprotective and reduces apoptosis due to various stimuli. In this work we demonstrate that guanosine has a neuroprotective effect, through the survey of data that we carry out.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77732239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Research on Terminalia arjuna: A Quantitative and Qualitative Assessment of Publications during 2004-18","authors":"K. Ahmed, B. Gupta, Jivesh Bansal, N. Singh, Ashok Kumar","doi":"10.5530/PHREV.2020.14.8","DOIUrl":"https://doi.org/10.5530/PHREV.2020.14.8","url":null,"abstract":"Cite this article: Ahmed KKM, Gupta BM, Singh N, Kumar A. Global Research on Terminalia arjuna: A Quantitative and Qualitative Assessment of Publications during 2004-18. Pharmacog Rev. 2020;14(27):45-52. ABSTRACT 683 global research publications on Terminalia arjuna were derived from the Scopus database during the last 22 years (1997-18) with a view to study its quantitative and qualitative aspects. The global publication data showed that the average annual and eleven-year cumulative global output of Terminalia arjuna research registered 8.33% and 169.19% growth. The plant global citation impact averaged to 16.92 citations per paper (CPP) in twenty-two years, which decreased from 36.02 CPP to 9.82 CPP from 1997-07 to 2008-18. The top 10 most productive countries together accounted for more than 100.0% global publication share and 99.13% global citation share during 1997-18. India, alone accounting for the highest and largest publication share of 82.43% and other 9 countries from 1.02% to 5.27% during 1997-18. Five out of top 10 countries, namely Iran (2.85), U.K. (1.94), Japan (1.22), USA (1.16) and Pakistan (1.09) registered relative citation index above the global average of 0.97. Pharmacology, toxicology and pharmaceutics, among seven broad subjects, contributed the largest publications share of 50.51%, followed by medicine (30.31%), biochemistry, genetics and molecular biology (26.52%), agricultural and biological sciences (21.52%) and other 3 sub-fields contribution varying from 4.54% to 10.83% during 1997-18. 239 global organizations and 309 global authors in global Terminalia arjuna research during 1997-18, of which the 15 most productive global organizations and authors together contributed 30.16% and 15.37% global publication share and 36.87% and 20.68% global citation share respectively during 1997-18. Hamdard University, Delhi, India (with 30 papers), Banaras Hindu University, Varanasi, India (22 papers) and All India Institute of Medical Sciences, New Delhi, India (19 papers), S. Dwivedi (with 11 papers), S.K. Maulik (10 papers) and P.C. Sil (8 papers) and Journal of Ethnopharmacology (with 26 papers), International Journal of Pharmacy and Pharmaceutical Sciences (15 papers), Asian Journal of Pharmaceutical and Clinical Research (14 papers) were the three leading organizations, authors and journals reporting global research in Terminalia arjuna during 199718.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"254 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76885910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DNA Based Molecular Markers: A Tool for Differentiation of Ayurvedic Raw Drugs and their Adulterants","authors":"Manasi Malgaonkar, Amey Shirolkar, S. Murthy, A. Mangal, S. Pawar","doi":"10.5530/PHREV.2020.14.11","DOIUrl":"https://doi.org/10.5530/PHREV.2020.14.11","url":null,"abstract":"Cite this article: Malgaonkar M, Shirolkar A, Murthy SN, Mangal AK, Pawar SD. “DNA Based Molecular Markers: A Tool for Differentiation of Ayurvedic Raw Drugs and their Adulterants”. Pharmacog Rev. 2020;14(27):72-81. ABSTRACT Recent advances in molecular techniques have generated several typing methods based on PCR for genetic assessment of genetic relatedness of plant species. Considering the medicinal importance of plants, it is essential to explore, discover and conserve genetic diversity of these plant species. Levels of polymorphisms represent genetic distance at intra-species level and method used to detect it is efficient marker for assessment of genetic relatedness. With this background, an attempt has been made to summarize the applicability of different DNA based molecular Markers for differentiation of Ayurvedic raw drugs and their adulterants considering the current practices and future perspectives.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"183 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74648531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toward a Novel Pharmacology and Therapeutic Understanding of Brazilian Propolis: A Meta-Analytical Approach","authors":"A. Sousa, Sabrina Z.C Moraes, A. Viana‐Júnior, Edílson D. Araújo","doi":"10.5530/PHREV.2020.1.1","DOIUrl":"https://doi.org/10.5530/PHREV.2020.1.1","url":null,"abstract":"Cite this article: Sousa ARS, Moraes SZC, Viana-Junior AB, Araujo ED. Toward a Novel Pharmacology and Therapeutic Understanding of Brazilian Propolis: A Meta-Analytical Approach. Pharmacog Rev. 2020;14(27):1-7. ABSTRACT This review article aims to use a meta-analytical approach to systematize and compare the main effects of green and red propolis, as determined through biological assays, in order to inform future preclinical tests and drug development for this natural product. A search for the full spectrum of their biological properties and possible pharmacological and medical applications found that propolis has anti-inflammatory, antioxidant, antiviral, antibacterial, antifungal, antiparasitic, anti-proliferative, anticarcinogenic, antinociceptive and neuroprotective effects, arising mainly from polyphenolic compounds. In order to identify and retrieve the most important published literature in this field in the last ten years a database search (LILACS, PubMed, Scopus and Web of Science) was performed. The MeSH terms and free text words used were: green propolis, red propolis, anti-inflammatory, antioxidant, antimicrobial, antiviral, antibacterial, anti-fungal, anti-parasitic, anti-carcinogenic, anti-proliferative, cytotoxicity, analgesic, anti-nociceptive, neuroprotective and neuroregenerative as well as their respective combinations. The meta-analysis outcomes showed that red propolis is superior to green propolis for healing, cytotoxic, antiparasitic and antibacterial applications; however, there are no significant differences between them as regards antifungal, antioxidant and antiinflammatory activities. Furthermore, it was found that red propolis contains greater amounts of flavonoids than green propolis, and that the supercritical extraction method was better in relation to phenolic acid yields, whereas the ethanolic method was better in respect of flavonoids. The key findings of this study can help to direct future work on this natural product in the pharmacological and medical fields.","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86893374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medicinal Plants Containing Coumarin or Essential Oils from the Brazilian Biome May be New Option for Treating Leishmaniasis?","authors":"E. S. Silveira, N. Rodrigues, Nuno J Machado, Francisco Rafael Marciano Fonseca, M. Teixeira, L. Leal","doi":"10.5530/PHREV.2020.14.9","DOIUrl":"https://doi.org/10.5530/PHREV.2020.14.9","url":null,"abstract":"","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"136 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86407969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phyto-Pharmacological Aspects of Cucumis melo var. agrestis: A Systematic Review","authors":"M. Kapoor, Chanchal Sharma, N. Kaur, G. Kaur, R. Kaur, Kajal Batra, J. Rani","doi":"10.5530/PHREV.2020.14.5","DOIUrl":"https://doi.org/10.5530/PHREV.2020.14.5","url":null,"abstract":"Aspects","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88923540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Celastrus paniculatus: A Bibliometric Assessment of Global Publications Output during 2001-18","authors":"K. Ahmed, B. Gupta, N. K. Singh, V. Thakur, Ashok Kumar","doi":"10.5530/PHREV.2020.14.3","DOIUrl":"https://doi.org/10.5530/PHREV.2020.14.3","url":null,"abstract":"","PeriodicalId":74432,"journal":{"name":"Pharmacognosy reviews","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75410421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}