Pathologie (Heidelberg, Germany)最新文献

[Molecular pathology in non-small-cell lung cancer: current and emerging biomarkers]. [非小细胞肺癌的分子病理学：当前和新兴的生物标志物]。

Pathologie (Heidelberg, Germany) Pub Date : 2025-04-03 DOI: 10.1007/s00292-025-01433-x

Helen Pasternack, Jutta Kirfel

引用次数: 0

[Challenges in the research and diagnosis of rare diseases]. [罕见疾病研究和诊断的挑战]。

Pathologie (Heidelberg, Germany) Pub Date : 2025-04-03 DOI: 10.1007/s00292-025-01426-w

Alexander Marx, Philipp Ströbel, Felix Bremmer, Daniel Nettersheim, Niels J Rupp, Eva Wardelmann, Wolfgang Hartmann

引用次数: 0

[Legal and organizational aspects of autopsy in Germany]. [德国尸体解剖的法律和组织方面]。

Pathologie (Heidelberg, Germany) Pub Date : 2025-03-17 DOI: 10.1007/s00292-025-01425-x

B Märkl, T Schaller

{"title":"[Legal and organizational aspects of autopsy in Germany].","authors":"B Märkl, T Schaller","doi":"10.1007/s00292-025-01425-x","DOIUrl":"https://doi.org/10.1007/s00292-025-01425-x","url":null,"abstract":"The article explores the legal and organizational aspects of autopsies in Germany. Despite their importance in clinical medicine, the number of clinical autopsies has been declining for decades due to work-related, organizational, and legal challenges. The COVID-19 pandemic led to a temporary resurgence of interest in autopsies, although this interest has since waned. Initiatives like the National Autopsy Network (NATON) and the National Autopsy Register (NAREG) have been established to promote research and quality assurance.Legally, autopsies in Germany are regulated at both federal and state levels. Variations in regulations between states, especially concerning consent and the definition of a corpse, complicate the process. Social insurance-related autopsies are crucial in clarifying occupational diseases and accidents.Organizationally, autopsies require consent from relatives, which is often a challenging step. However, the introduction of remuneration for clinical autopsies has improved the framework. Initiatives such as the S1 guideline and international research projects have reinforced the role of autopsies. The article underscores the importance of autopsies in quality assurance and research, especially given the rise in occupational diseases and the need for improved clinical diagnoses.","PeriodicalId":74402,"journal":{"name":"Pathologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Teaching pathology in Germany : The current state of teaching at pathological institutes of German universities in 2024]. 【德国病理学教学：2024年德国大学病理研究所教学现状】。

Pathologie (Heidelberg, Germany) Pub Date : 2025-03-07 DOI: 10.1007/s00292-025-01424-y

Alexander Fichtner, Christiane Kümpers

{"title":"[Teaching pathology in Germany : The current state of teaching at pathological institutes of German universities in 2024].","authors":"Alexander Fichtner, Christiane Kümpers","doi":"10.1007/s00292-025-01424-y","DOIUrl":"https://doi.org/10.1007/s00292-025-01424-y","url":null,"abstract":"The teaching of pathology at the 36 university departments of pathology is influenced by different curriculum structures. Teaching formats and the number of course hours vary considerably in some cases, partly due to structural circumstances at different locations. The teaching content appears to be largely congruent. Most of the medical staff are involved in teaching. The postgraduate training assistants would like good training and time to prepare the courses. The institute directors predominantly rate teaching as very important or important for them personally, whereas their satisfaction with the overall teaching situation at the locations is rated as \"moderate.\" Students are largely satisfied with teaching. In addition to structured, interdisciplinary, and practical teaching, suggestions for improvement include, in particular, opportunities to participate in autopsies, the use of digital formats (e.g., in lectures, microscopy courses), a more precise introduction to the assessment of histopathological findings, and a better presentation of the fields of activity in pathology. Attempts should be made throughout Germany to standardize teaching more in order to better represent the subject to deaneries and examination offices. In addition, efforts should be made to modernize teaching content and methods to make the subject more attractive to potential new recruits.","PeriodicalId":74402,"journal":{"name":"Pathologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Exanthematic drug eruption]. [外显药物喷发]。

Pathologie (Heidelberg, Germany) Pub Date : 2025-03-01 Epub Date: 2025-02-18 DOI: 10.1007/s00292-025-01418-w

Mirjana Ziemer, Elisabeth Livingstone

{"title":"[Exanthematic drug eruption].","authors":"Mirjana Ziemer, Elisabeth Livingstone","doi":"10.1007/s00292-025-01418-w","DOIUrl":"10.1007/s00292-025-01418-w","url":null,"abstract":"Background: Besides reactions of the IgE-mediated immediate type, medicamentous therapies can cause a variety of different mucocutaneous adverse events. Exanthematous manifestations require a fast and certain diagnosis due to their extent, sometimes rapid progression, and mucous membrane or organ involvement.Objectives: The spectrum of non-IgE-mediated exanthematic drug reactions is covered.Material and methods: The most relevant reactions are portrayed clinically and histopathologically.Results: Displayed are classical maculo-papular drug eruption, lichenoid drug reaction, acute generalized exanthematic pustulosis (AGEP), severe potentially life-threatening drug reactions such as Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) as well as generalized bullous fixed drug eruption (GBFDE), drug reaction with eosinophilia and systemic symptoms (DRESS), and some others.Conclusions: Cutaneous drug-related side effects cover a broad spectrum. Important for the correct treatment is a reliable diagnosis. In the case of severe, life-threatening drug reactions, however, permanent discontinuation of the drug is essential.","PeriodicalId":74402,"journal":{"name":"Pathologie (Heidelberg, Germany)","volume":" ","pages":"90-100"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Clues in dermatopathological diagnostics]. [皮肤病理诊断的线索]。

Pathologie (Heidelberg, Germany) Pub Date : 2025-03-01 Epub Date: 2024-12-09 DOI: 10.1007/s00292-024-01400-y

Almut Böer-Auer

引用次数: 0

[HSVN - hepatic small vessel neoplasm]. [HSVN - 肝小血管肿瘤]。

Pathologie (Heidelberg, Germany) Pub Date : 2025-03-01 Epub Date: 2024-08-14 DOI: 10.1007/s00292-024-01349-y

Su Ir Lyu, Jörn Meinel, Uta Drebber

引用次数: 0

[A lump in the male breast-case report of an unusual tumor manifestation]. [男性乳房肿块--异常肿瘤表现的病例报告]。

Pathologie (Heidelberg, Germany) Pub Date : 2025-03-01 Epub Date: 2024-10-16 DOI: 10.1007/s00292-024-01369-8

Torsten Hansen, E Z Kovacs, J Kriegsmann, S M Jud

引用次数: 0

[Establishment of a German ICCR dataset : Translation and integration of SNOMED CT using the example of TUR-B]. [德国ICCR数据集的建立：以turb为例的SNOMED CT的翻译和整合]。

Pathologie (Heidelberg, Germany) Pub Date : 2025-03-01 Epub Date: 2024-12-05 DOI: 10.1007/s00292-024-01398-3

J Dörenberg, C J Schmidt, T Berlage, R Knüchel-Clarke

{"title":"[Establishment of a German ICCR dataset : Translation and integration of SNOMED CT using the example of TUR-B].","authors":"J Dörenberg, C J Schmidt, T Berlage, R Knüchel-Clarke","doi":"10.1007/s00292-024-01398-3","DOIUrl":"10.1007/s00292-024-01398-3","url":null,"abstract":"Background: The structured recording of data from histopathological findings and their interoperability is critical for quality assurance in pathology.Materials and methods: To harmonize the content of the reports, the International Collaboration on Cancer Reporting (ICCR) has defined standardized datasets. These datasets are not yet available in German nationwide. This gap is addressed here using the transurethral bladder resection (TUR-B) dataset as a use case.Results: We describe the process of establishing the datasets by carrying out translation, mapping on SNOMED CT codes, and using SNOMED CTs hierarchy to fill dropdown menus. Furthermore, we identified rules for checking for self-consistency of reports by using the example of the TUR bladder.Discussion: With this article, we have created an example of a German version of the ICCR TUR‑B dataset including mapping to the SNOMED CT terminology. Further activities should include the definition of overarching cancer disease models to further exploit the potential of SNOMED CT.","PeriodicalId":74402,"journal":{"name":"Pathologie (Heidelberg, Germany)","volume":" ","pages":"108-114"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11861236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142788051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[News from the world of dermatopathology]. [来自皮肤病理学世界的新闻]。

Pathologie (Heidelberg, Germany) Pub Date : 2025-03-01 Epub Date: 2025-02-25 DOI: 10.1007/s00292-025-01422-0

Dieter Metze, Erhard Bierhoff

引用次数: 0