Oxygen (Basel, Switzerland)最新文献_第5页

β-Cyclodextrin-Aided Aqueous Extraction of Antioxidant Polyphenols from Peppermint (Mentha × piperita L.) β-环糊精辅助水提取薄荷抗氧化多酚

Oxygen (Basel, Switzerland) Pub Date : 2022-09-29 DOI: 10.3390/oxygen2040029

V. Athanasiadis, D. Palaiogiannis, Eleni Bozinou, S. Lalas, D. Makris

{"title":"β-Cyclodextrin-Aided Aqueous Extraction of Antioxidant Polyphenols from Peppermint (Mentha × piperita L.)","authors":"V. Athanasiadis, D. Palaiogiannis, Eleni Bozinou, S. Lalas, D. Makris","doi":"10.3390/oxygen2040029","DOIUrl":"https://doi.org/10.3390/oxygen2040029","url":null,"abstract":"This study explored the use of β-cyclodextrin (β-CD) as an additive to improve the aqueous extraction of antioxidant polyphenols from peppermint (Mentha × piperita). For this purpose, an initial single-factor screening was performed to test the effect of β-CD concentration on the yield of polyphenol extraction. In the following step, the extraction process was optimized through response surface methodology, considering β-CD and temperature as the process variables. The experimental design included the yield in total polyphenols and total flavonoids, the ferric-reducing power and the antiradical activity as the responses. The optimization showed that each response was maximized at different levels of β-CD concentration, but in all cases, 80 °C was the optimum extraction temperature. The composition of the extracts produced was profiled by high-performance liquid chromatography (HPLC). A comparison of the β-CD extract with the aqueous and hydroethanolic extracts revealed that the addition of β-CD at a specified concentration might boost aqueous polyphenol extraction. On the other hand, the hydroethanolic extract exhibited the richest polyphenolic profile. It was also shown that the β-CD extracts might possess improved antiradical activity. It was concluded that β-CD-aided polyphenol extraction from M. piperita may provide extracts with enriched polyphenolic composition and improved antioxidant characteristics, and this technique may be considered an alternative to solvent extraction.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47812028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

The Effect of Additives on the Hydrothermal Synthesis and Thermochromic Performance of Monoclinic Vanadium Dioxide Powder 添加剂对单斜二氧化钒粉体水热合成及热致变色性能的影响

Oxygen (Basel, Switzerland) Pub Date : 2022-09-28 DOI: 10.3390/oxygen2040028

L. Zouridi, E. Gagaoudakis, Eleni Mantsiou, Theodora Dragani, Xristina Maragaki, E. Aperathitis, G. Kiriakidis, V. Binas

{"title":"The Effect of Additives on the Hydrothermal Synthesis and Thermochromic Performance of Monoclinic Vanadium Dioxide Powder","authors":"L. Zouridi, E. Gagaoudakis, Eleni Mantsiou, Theodora Dragani, Xristina Maragaki, E. Aperathitis, G. Kiriakidis, V. Binas","doi":"10.3390/oxygen2040028","DOIUrl":"https://doi.org/10.3390/oxygen2040028","url":null,"abstract":"Monoclinic vanadium dioxide VO2(M) is a well-known thermochromic material, with its critical transition temperature (68 °C) being the closest to room temperature (RT). Among the variety of grown methods, hydrothermal synthesis is a simple and cost-effective technique to grow thermochromic VO2 in the form of powder. In the present work, VO2 nanoparticles were prepared by hydrothermal synthesis in mild conditions, followed by a thermal annealing process at 700 °C under nitrogen flow for two hours. Vanadium pentoxide (V2O5) was used as the vanadium precursor, while two different reducing agents, namely oxalic and succinic acid, were employed for the reduction of V2O5 to VO2. Additionally, urea as well as thiourea were used as additives, in order to investigate their effects on the thermochromic performance of VO2. As a result, the VO2 (M) phase was obtained after annealing the crystalline powder, grown hydrothermally using oxalic acid and thiourea as a reducing agent and additive, respectively. This synthesis had a high yield of 90%, and led to a VO2(M) powder of high purity and crystallinity. In particular, the VO2 (M) nanoparticles had an average crystallite size of approximately 45 nm, a critical transition temperature of approximately 68 °C and a hysteresis width of 11 °C.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41860526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Ambiguous Aspects of Oxygen 氧的模糊方面

Oxygen (Basel, Switzerland) Pub Date : 2022-09-14 DOI: 10.3390/oxygen2030027

G. Napolitano, G. Fasciolo, P. Venditti

{"title":"The Ambiguous Aspects of Oxygen","authors":"G. Napolitano, G. Fasciolo, P. Venditti","doi":"10.3390/oxygen2030027","DOIUrl":"https://doi.org/10.3390/oxygen2030027","url":null,"abstract":"For most living beings, oxygen is an essential molecule for survival, being the basis of biological oxidations, which satisfy most of the energy needs of aerobic organisms. Oxygen can also behave as a toxic agent posing a threat to the existence of living beings since it can give rise to reactive oxygen species (ROS) that can oxidise biological macromolecules, among which proteins and lipids are the preferred targets. Oxidative damage can induce cell, tissue, and organ dysfunction, which leads to severe body damage and even death. The survival of the aerobic organism depends on the development of an elaborate antioxidant defence system adapted to the normal level of atmospheric oxygen. The production of ROS in the aerobic organism can occur accidentally from exposure to pollutants or radiation, but occurs constantly during normal metabolic reactions. Cells have evolved using ROS to their advantage. Indeed, ROS are used as signalling molecules in numerous physiological processes, including muscle contraction, regulation of insulin release, and adaptation to environmental changes. Therefore, supplementation with antioxidants must be used wisely. A low level of ROS is essential for adaptation processes, so an excess of antioxidants can be harmful. Conversely, in conditions where ROS production increases, antioxidants can be useful to avoid cellular dysfunction.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47372673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Home Oxygen Therapy (HOT) in Stable Chronic Obstructive Pulmonary Disease (COPD) and Interstitial Lung Disease (ILD): Similarities, Differences and Doubts 稳定型慢性阻塞性肺病（COPD）和间质性肺病（ILD）的家庭氧疗（HOT）：相似、差异和疑问

Oxygen (Basel, Switzerland) Pub Date : 2022-09-13 DOI: 10.3390/oxygen2030026

A. Melani, R. M. Refini, S. Croce, M. Messina

{"title":"Home Oxygen Therapy (HOT) in Stable Chronic Obstructive Pulmonary Disease (COPD) and Interstitial Lung Disease (ILD): Similarities, Differences and Doubts","authors":"A. Melani, R. M. Refini, S. Croce, M. Messina","doi":"10.3390/oxygen2030026","DOIUrl":"https://doi.org/10.3390/oxygen2030026","url":null,"abstract":"This narrative paper reviews the current knowledge of Home Oxygen Therapy (HOT) in stable Chronic Obstructive Pulmonary Disease (COPD) and Interstitial Lung Disease (ILD), two major causes of Long-Term Oxygen Therapy (LTOT) prescription. There is evidence that LTOT improves survival in COPD subjects with chronic severe respiratory failure. HOT is also used to contrast exercise and sleeping hypoxemia and to improve Quality of Life (QoL) and symptoms. Ambulatory Oxygen Therapy (AOT) did not assure generalized improvements in symptoms and Quality of Life (QoL) of COPD subjects. There is short-term evidence in a real-life study that AOT may improve QoL in ILD subjects with Exercise Oxygen Desaturation (EOD) and exertional dyspnea. There are some differences between guidelines and practices, which translate into variations in characteristics and rates of ILD and COPD subjects admitted to LTOT and AOT. Indications on titration of oxygen flow and the best oxygen delivery device for optimal management of AOT in COPD and ILD subjects are often vague or lacking. More work is needed for optimizing and customizing HOT in COPD and ILD subjects.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44428751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Plant Antioxidants Affect Human and Gut Health, and Their Biosynthesis Is Influenced by Environment and Reactive Oxygen Species 植物抗氧化剂影响人体和肠道健康，其生物合成受环境和活性氧的影响

Oxygen (Basel, Switzerland) Pub Date : 2022-09-01 DOI: 10.3390/oxygen2030025

D. Navarre, Meijun Zhu, H. Hellmann

引用次数: 0

Molecular oxygen as a probe molecule in EPR spin-labeling studies of membrane structure and dynamics. 分子氧作为 EPR 自旋标记膜结构和动态研究的探针分子。

Oxygen (Basel, Switzerland) Pub Date : 2022-09-01 Epub Date: 2022-08-04 DOI: 10.3390/oxygen2030021

Witold K Subczynski, Justyna Widomska, Marija Raguz, Marta Pasenkiewicz-Gierula

{"title":"Molecular oxygen as a probe molecule in EPR spin-labeling studies of membrane structure and dynamics.","authors":"Witold K Subczynski, Justyna Widomska, Marija Raguz, Marta Pasenkiewicz-Gierula","doi":"10.3390/oxygen2030021","DOIUrl":"10.3390/oxygen2030021","url":null,"abstract":"Molecular oxygen (O2) is the perfect probe molecule for membrane studies carried out using the saturation recovery EPR technique. O2 is a small, paramagnetic, hydrophobic enough molecule that easily partitions into a membrane's different phases and domains. In membrane studies, the saturation recovery EPR method requires two paramagnetic probes: a lipid-analog nitroxide spin label and an oxygen molecule. The experimentally derived parameters of this method are the spin-lattice relaxation times (T 1s) of spin labels and rates of bimolecular collisions between O2 and the nitroxide fragment. Thanks to the long T 1 of lipid spin labels (from 1 to 10 μs), the approach is very sensitive to changes of the local (around the nitroxide fragment) O2 diffusion-concentration product. Small variations in the lipid packing affect O2 solubility and O2 diffusion, which can be detected by the shortening of T 1 of spin labels. Using O2 as a probe molecule and a different lipid spin label inserted into specific phases of the membrane and membrane domains allows data about the lateral arrangement of lipid membranes to be obtained. Moreover, using a lipid spin label with the nitroxide fragment attached to its head group or a hydrocarbon chain at different positions also enables data about molecular dynamics and structure at different membrane depths to be obtained. Thus, the method can be used to investigate not only the lateral organization of the membrane (i.e., the presence of membrane domains and phases), but also the depth-dependent membrane structure and dynamics, and, hence, the membrane properties in three dimensions.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10134812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photosynthetic Production of Molecular Oxygen by Water Oxidation 水氧化作用下分子氧的光合作用

Oxygen (Basel, Switzerland) Pub Date : 2022-08-26 DOI: 10.3390/oxygen2030024

L. Björn

引用次数: 0

Correlation of the Isotropic NMR Chemical Shift with Oxygen Coordination Distances in Periodic Solids 周期固体中各向同性核磁共振化学位移与氧配位距离的关系

Oxygen (Basel, Switzerland) Pub Date : 2022-08-05 DOI: 10.3390/oxygen2030023

Jennifer Steinadler, O. E. Zeman, T. Bräuniger

{"title":"Correlation of the Isotropic NMR Chemical Shift with Oxygen Coordination Distances in Periodic Solids","authors":"Jennifer Steinadler, O. E. Zeman, T. Bräuniger","doi":"10.3390/oxygen2030023","DOIUrl":"https://doi.org/10.3390/oxygen2030023","url":null,"abstract":"In Nuclear Magnetic Resonance (NMR) spectroscopy, the isotropic chemical shift δiso is a measure of the electron density around the observed nuclide. For characterization of solid materials and compounds, it is desirable to find correlations between δiso and structural parameters such as coordination numbers and distances to neighboring atoms. Correlations of good quality are easier to find when the coordination sphere is formed by only one element, as the electron density is obviously strongly dependent on the atomic number. The current study is therefore restricted to nuclides in pure oxygen coordination. It is shown that the isotropic shift δiso correlates well with the average oxygen distances (as defined by the coordination sphere) for the nuclides 23Na (with spin I=3/2), 27Al (I=5/2), and 43Ca (I=7/2), using literature data for a range of periodic solids. It has been previously suggested for 207Pb (I=1/2) that δiso may alternatively be related to the shortest oxygen distance in the structure, and our study corroborates this also for the nuclides considered here. While the correlation with the minimal distance is not always better, it has the advantage of being uniquely defined. In contrast, the average distance is strongly dependent on the designation of the oxygen coordination sphere, which may be contentious in some crystal structures.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45237760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Roles of Reactive Oxygen Species and Autophagy in the Pathogenesis of Cisplatin-Induced Acute Kidney Injury 活性氧和自噬在顺铂急性肾损伤发病机制中的作用

Oxygen (Basel, Switzerland) Pub Date : 2022-08-05 DOI: 10.3390/oxygen2030022

Sayuri Yoshikawa, Kurumi Taniguchi, Haruka Sawamura, Yuka Ikeda, Ai Tsuji, Satoru Matsuda

{"title":"Roles of Reactive Oxygen Species and Autophagy in the Pathogenesis of Cisplatin-Induced Acute Kidney Injury","authors":"Sayuri Yoshikawa, Kurumi Taniguchi, Haruka Sawamura, Yuka Ikeda, Ai Tsuji, Satoru Matsuda","doi":"10.3390/oxygen2030022","DOIUrl":"https://doi.org/10.3390/oxygen2030022","url":null,"abstract":"Cisplatin-induced acute kidney injury (AKI) is the main factor restraining the clinical application of cisplatin. The AKI is associated with high mortality and morbidity, but no effective pharmacological treatment is available at present. As increased levels of reactive oxygen species (ROS) may promote the progression of the injury, the elimination of ROS has been considered as an effective method to prevent the cisplatin-induced AKI. In addition, it has been revealed that an inducer of autophagy could protect kidney cells in the autophagy dependent manner. Induction of autophagy could also modulate the production of ROS in cases of renal injury. Therefore, kidney-targeted antioxidants and/or autophagy are urgently required for the better treatment of AKI. Accumulating evidence has indicated the important roles of gut microbiota in the pathogenesis of AKI. In addition, there is a scientific basis for considering future clinical applications of probiotics and/or prebiotics to treat cisplatin-induced AKI. Thus, gut microbiota might be a promising therapeutic target via the alteration of autophagy for the cancer therapy-induced nephrotoxicity.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49424148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Correlation between Microbial Population and Oxidative Stability of the Yogurt-Based Tzatziki Salad 酸奶沙拉中微生物种群和氧化稳定性的相关性

Oxygen (Basel, Switzerland) Pub Date : 2022-07-28 DOI: 10.3390/oxygen2030020

Eleni Bozinou, V. Athanasiadis, Theodoros G. Chatzimitakos, C. Salakidou, V. Dourtoglou, S. Lalas

{"title":"Correlation between Microbial Population and Oxidative Stability of the Yogurt-Based Tzatziki Salad","authors":"Eleni Bozinou, V. Athanasiadis, Theodoros G. Chatzimitakos, C. Salakidou, V. Dourtoglou, S. Lalas","doi":"10.3390/oxygen2030020","DOIUrl":"https://doi.org/10.3390/oxygen2030020","url":null,"abstract":"Tzatziki is a deli salad widely consumed in the Eastern Mediterranean and Balkan countries, and it is acknowledged for its health benefits. So far, it is proved to exhibit extreme resistance to microbial spoilage by (pathogenic) microorganisms and microbial self-stabilization, but no research was carried out regarding its oxidative stability despite the fact that it contains a large amount of lipids. In this study, the factor that affects the oxidative stability of tzatziki was exploited. Different samples of tzatziki salad were prepared and stored for 16 or 27 days, depending on the conducted experiment. They varied in the type of yogurt (set yogurt or traditional Greek-style yogurt), the type of oil (olive oil or soybean oil), and the addition or not of preservatives, garlic, and cucumber. Samples were analyzed in terms of oxidative stability (by the Rancimat method), colony-forming units, and tocopherol content throughout the storage period. Among the examined parameters, no correlation between the tocopherol content and oxidative stability was recorded. However, a strong correlation between the microbial population and the oxidative stability was recorded. Therefore, this correlation can be used to prepare tzatziki salads with increased shelf life and decreased flavor deterioration (due to oxidation). Moreover, such correlations should be further exploited for other foods so as to promote their stability.","PeriodicalId":74387,"journal":{"name":"Oxygen (Basel, Switzerland)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47002544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1