Filippo Migliorini, Riccardo Giorgino, Francesco Oliva, Gennaro Pipino, Michael Kurt Memminger, Nicola Maffulli
{"title":"No significant short-term advantages of corticosteroids-augmented intra-articular injections of hyaluronic acid for knee osteoarthritis : A meta-analysis.","authors":"Filippo Migliorini, Riccardo Giorgino, Francesco Oliva, Gennaro Pipino, Michael Kurt Memminger, Nicola Maffulli","doi":"10.1007/s00132-025-04762-0","DOIUrl":"10.1007/s00132-025-04762-0","url":null,"abstract":"<p><strong>Introduction: </strong>The present meta-analysis investigated whether augmenting hyaluronic acid (HA) with corticosteroids (CCs) is more effective than HA in isolation in patients with knee osteoarthritis (OA). The outcomes of interest were the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores.</p><p><strong>Methods: </strong>This study was conducted according to the 2020 PRISMA statement. In September 2025 the following databases were accessed: PubMed, Web of Science, Google Scholar and Embase. All head-to-head randomized controlled trials (RCTs) comparing intra-articular injections of HA in isolation versus HA augmented with CCs were accessed.</p><p><strong>Results: </strong>Data from 216 patients were collected and 74% (162 of 216) of the patients were women. The mean patient age was 57.7 ± 4.4 years and the mean body mass index (BMI) was 28.2 ± 3.0 kg/m<sup>2</sup>. No difference was found in WOMAC scores between 3-4 months of follow-up (P = 0.9); No difference was found in WOMAC scores between 4-6 months of follow-up (P = 0.5).</p><p><strong>Conclusion: </strong>The current level I of evidence suggests that intra-articular HA injections augmented with CCs do not appear to provide clinically relevant advantages in WOMAC outcomes within 3-6 months of follow-up.</p>","PeriodicalId":74375,"journal":{"name":"Orthopadie (Heidelberg, Germany)","volume":" ","pages":"825-832"},"PeriodicalIF":0.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13601200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145947083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evidenz in der computerassistierten Orthopädie – zwischen Innovation und Patientennutzen.","authors":"Tobias Renkawitz","doi":"10.1007/s00132-026-04883-0","DOIUrl":"https://doi.org/10.1007/s00132-026-04883-0","url":null,"abstract":"","PeriodicalId":74375,"journal":{"name":"Orthopadie (Heidelberg, Germany)","volume":"55 10","pages":"765-766"},"PeriodicalIF":0.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149032240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susanne Feihl, S Meller, Y Gramlich, R von Eisenhart-Rothe, R Hube, P Radünzel, R Otchwemah, Gunnar Hischebeth
{"title":"[Antimicrobial therapy of periprosthetic joint infection : Summary of AE guidelines (2026)].","authors":"Susanne Feihl, S Meller, Y Gramlich, R von Eisenhart-Rothe, R Hube, P Radünzel, R Otchwemah, Gunnar Hischebeth","doi":"10.1007/s00132-026-04851-8","DOIUrl":"10.1007/s00132-026-04851-8","url":null,"abstract":"<p><strong>Background: </strong>Periprosthetic joint infections (PJI) are among the most severe and complex complications following joint arthroplasty and require a structured interdisciplinary treatment approach. In addition to an adequate surgical strategy, pathogen-directed and patient-specific anti-infective therapy plays a central role in successful management.</p><p><strong>Methods: </strong>Based on a comprehensive literature review and current guidelines, followed by a structured consensus process within the interdisciplinary working group of the \"German Society for Arthroplasty (Deutsche Gesellschaft für Endoprothetik e. V.)\", available treatment options were evaluated and consensus recommendations for the anti-infective management of PJI were developed.</p><p><strong>Results: </strong>The cornerstone of PJI treatment is surgical management combined with an initial empiric followed by targeted antibiotic therapy. Staphylococci represent the most frequently identified pathogens, with the biofilm-active antibiotic rifampin playing a key role in their treatment. Fluoroquinolones are primarily used for infections caused by gram-negative pathogens but are also employed in combination with rifampin for staphylococcal infections. For other clinically relevant pathogen groups, differentiated consensus-based treatment recommendations were established. The recommended total duration of antibiotic therapy is generally approximately 12 weeks.</p><p><strong>Conclusion: </strong>Anti-infective therapy represents a key component in the successful treatment of periprosthetic joint infections. An individualized therapeutic approach, tailored to the respective surgical treatment strategy, is essential.</p>","PeriodicalId":74375,"journal":{"name":"Orthopadie (Heidelberg, Germany)","volume":" ","pages":"812-821"},"PeriodicalIF":0.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13601107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148946259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Computer-assisted spine surgery : Current status and future perspectives].","authors":"Lukas Schönnagel, Thilo Khakzad, Matthias Pumberger, Maximillian Müllner","doi":"10.1007/s00132-026-04877-y","DOIUrl":"10.1007/s00132-026-04877-y","url":null,"abstract":"<p><p>Computer-assisted spine surgery has evolved from fluoroscopy-based techniques to advanced navigation and robotic systems. These technologies aim to improve intraoperative precision, enhance instrument guidance, and increase reproducibility of surgical workflows. Modern platforms integrate preoperative planning, intraoperative imaging, and real-time tracking to support surgical decision-making. As adoption increases, their role in clinical practice continues to be critically evaluated. This review provides an overview of the development and current state of computer-assisted and robotic spine surgery, outlining key technological principles and clinical applications. In addition, it addresses current challenges, including workflow integration, resource requirements, and limitations of existing systems. Finally, emerging developments such as automation, improved imaging integration, and data-driven approaches are discussed to contextualize the potential future impact of these technologies on spine care.</p>","PeriodicalId":74375,"journal":{"name":"Orthopadie (Heidelberg, Germany)","volume":" ","pages":"777-783"},"PeriodicalIF":0.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148875991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Schwarze, P W Gaidzik, A-K Kanti, M Schiltenwolf
{"title":"[Limits to the extension of surgical procedures].","authors":"Martin Schwarze, P W Gaidzik, A-K Kanti, M Schiltenwolf","doi":"10.1007/s00132-025-04740-6","DOIUrl":"10.1007/s00132-025-04740-6","url":null,"abstract":"","PeriodicalId":74375,"journal":{"name":"Orthopadie (Heidelberg, Germany)","volume":" ","pages":"822-824"},"PeriodicalIF":0.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145411205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Muscle injuries in sport : High clinical relevance and diagnostic challenges].","authors":"Tobias Würfel, Julian Mehl, Hannes Degenhardt","doi":"10.1007/s00132-026-04862-5","DOIUrl":"10.1007/s00132-026-04862-5","url":null,"abstract":"<p><p>Muscle injuries are among the most frequent sports-related injuries, particularly affecting the lower extremities in high-performance sports. This article provides a structured, evidence-based approach to diagnostics, treatment and prevention. A key aspect is the differentiation between functional and structural muscle injuries, as this distinction determines the treatment strategies. Despite modern imaging the clinical examination remains the diagnostic gold standard, while magnetic resonance imaging (MRI) findings must always be critically interpreted in the clinical context due to relevant discrepancies. Acute management is based on the POLICE principle, emphasizing early functional, load-adapted treatment. Eccentric strengthening exercises represent the most effective preventive strategy and significantly reduce the risk of injury. Return to play decisions should not rely solely on pain resolution but must include functional and structural recovery criteria to minimize reinjury risk.</p>","PeriodicalId":74375,"journal":{"name":"Orthopadie (Heidelberg, Germany)","volume":" ","pages":"839-848"},"PeriodicalIF":0.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefano Pagano, Sebastian Dendorfer, Soja Wasinkin, Tobias Renkawitz
{"title":"[Digital rehabilitation with smart devices : Clinical evidence and practical implications].","authors":"Stefano Pagano, Sebastian Dendorfer, Soja Wasinkin, Tobias Renkawitz","doi":"10.1007/s00132-026-04879-w","DOIUrl":"10.1007/s00132-026-04879-w","url":null,"abstract":"<p><strong>Background: </strong>Digital rehabilitation using apps, wearables, sensor feedback, and remote follow-up is being increasingly used in orthopedics. Clinically, the key issue is not technical novelty but whether function, mobility, adherence, and healthcare costs are significantly improved compared with conventional care.</p><p><strong>Objectives: </strong>To provide a clinically oriented appraisal of current evidence on smart-device-based rehabilitation in orthopedics and derive practical implications for everyday care.</p><p><strong>Materials and methods: </strong>Clinically oriented narrative review with a structured appraisal of selected systematic reviews, meta-analyses, and relevant original studies on smart-device-based rehabilitation in orthopedics.</p><p><strong>Results: </strong>The strongest evidence is available after knee and hip arthroplasty. App-based telerehabilitation usually achieves comparable functional outcomes to conventional rehabilitation and may improve selected performance measures and reduce physiotherapy use. Simple activity trackers mainly increase step count but have smaller effects on pain and disease-specific scores. Sensor-based biofeedback and VR/AR approaches appear more promising but are partly supported by smaller and heterogeneous studies. Outside arthroplasty, positive signals exist for hip fracture rehabilitation, knee osteoarthritis, and selected spine programs.</p><p><strong>Conclusions: </strong>Digital rehabilitation is not a uniform intervention. In practice, patient selection, adequate instruction, feedback, and a realistic appraisal of evidence quality are more important than choosing the newest device.</p>","PeriodicalId":74375,"journal":{"name":"Orthopadie (Heidelberg, Germany)","volume":" ","pages":"796-801"},"PeriodicalIF":0.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148875967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Computer-assisted virtual pre-operative planning for the treatment of pilon fractures. A retrospective cohort study with propensity score matching].","authors":"Dirk Stengel","doi":"10.1007/s00132-026-04884-z","DOIUrl":"10.1007/s00132-026-04884-z","url":null,"abstract":"","PeriodicalId":74375,"journal":{"name":"Orthopadie (Heidelberg, Germany)","volume":" ","pages":"836-838"},"PeriodicalIF":0.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148972700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Sayed Kotb, Mostafa AbdElnabee Abouzaid, Mohamed Amr Hemida, Ayman Abdelaziz Bassiony, Haitham E Sallam
{"title":"Knee and ankle functional outcome after anterior cruciate ligament reconstruction with a peroneus longus tendon autograft : A prospective clinical study.","authors":"Ahmed Sayed Kotb, Mostafa AbdElnabee Abouzaid, Mohamed Amr Hemida, Ayman Abdelaziz Bassiony, Haitham E Sallam","doi":"10.1007/s00132-026-04892-z","DOIUrl":"https://doi.org/10.1007/s00132-026-04892-z","url":null,"abstract":"<p><strong>Background: </strong>An entire peroneus longus tendon (PLT) autograft has been introduced as an alternative graft for anterior cruciate ligament (ACL) reconstruction but concerns remain regarding donor-site effects on ankle and foot function.</p><p><strong>Objective: </strong>This study evaluated knee outcome, ankle/foot function and footprint changes after ACL reconstruction using the entire peroneus longus autograft.</p><p><strong>Methods: </strong>This non-randomized controlled clinical trial included 26 male patients (mean age 29.7 ± 5.8 years) with isolated ACL tears who underwent arthroscopic ACL reconstruction using an ipsilateral entire PLT autograft at Ain Shams University Hospitals and Dar Al-Shefa Hospitals. Patients were assessed preoperatively and at 6 months using the Foot Arch Index (FAI) from static footprint analysis, American Orthopedic Foot and Ankle Society (AOFAS) ankle-hindfoot score, Foot and Ankle Disability Index (FADI) and International Knee Documentation Committee (IKDC) score.</p><p><strong>Results: </strong>The FAI significantly increased from 0.26 ± 0.05 preoperatively to 0.27 ± 0.04 at 6 months (P = 0.027). Knee outcome improved, with the IKDC increasing from 68 ± 0.5 to 84.0 ± 0 (P = 0.017). Ankle/foot functional scores did not change significantly, with the AOFAS remaining at 98.8 ± 2.31 preoperatively versus 98.8 ± 2.45 postoperatively (P = 1) and the FADI showing no significant difference (99 ± 1.73 vs. 99.3 ± 1.41; P = 0.212).</p><p><strong>Conclusion: </strong>Reconstruction of the ACL using the entire PLT autograft was associated with improved knee outcome at 6 months without significant deterioration in ankle/foot function, alongside a small but statistically significant increase in FAI.</p>","PeriodicalId":74375,"journal":{"name":"Orthopadie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149082457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}