Connor W Barth, Lei G Wang, Antonio Montano, Alexander L Antaris, Alwin Klaassen, Jonathan Sorger, Darcy A Kerr, Eric R Henderson, Adam W G Alani, Summer L Gibbs
{"title":"Lead Optimization of Nerve-Specific Fluorophores for Image-Guided Nerve Sparing Surgical Procedures.","authors":"Connor W Barth, Lei G Wang, Antonio Montano, Alexander L Antaris, Alwin Klaassen, Jonathan Sorger, Darcy A Kerr, Eric R Henderson, Adam W G Alani, Summer L Gibbs","doi":"10.1364/OMP.2021.OW3E.3","DOIUrl":"https://doi.org/10.1364/OMP.2021.OW3E.3","url":null,"abstract":"<p><p>Nerve damage is a major complication of surgery, causing pain and loss of function. We have identified novel near-infrared nerve-specific fluorophores that provide excellent nerve contrast with the ability to identify buried nerve tissue.</p>","PeriodicalId":74365,"journal":{"name":"Optical molecular probes, imaging and drug delivery","volume":"2021 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431774/pdf/nihms-1828140.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10671313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AlliGator: A Phasor Computational Platform for Fast <i>in vivo</i> Lifetime Analysis.","authors":"Sez-Jade Chen, Nattawut Sinsuebphon, Margarida Barroso, Xavier Intes, Xavier Michalet","doi":"10.1364/omp.2017.omtu2d.2","DOIUrl":"10.1364/omp.2017.omtu2d.2","url":null,"abstract":"<p><p>A fast time-gated phasor analysis tool was developed and used to monitor kinetics of NIR FLIM-FRET <i>in vitro</i> and <i>in vivo</i>. The results were validated by comparison with standard two-component fluorescence decay fitting analysis.</p>","PeriodicalId":74365,"journal":{"name":"Optical molecular probes, imaging and drug delivery","volume":"2017 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772506/pdf/nihms-1693534.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39854144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}