Connor W Barth, Lei G Wang, Antonio Montano, Alexander L Antaris, Alwin Klaassen, Jonathan Sorger, Darcy A Kerr, Eric R Henderson, Adam W G Alani, Summer L Gibbs
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Lead Optimization of Nerve-Specific Fluorophores for Image-Guided Nerve Sparing Surgical Procedures.
Nerve damage is a major complication of surgery, causing pain and loss of function. We have identified novel near-infrared nerve-specific fluorophores that provide excellent nerve contrast with the ability to identify buried nerve tissue.