{"title":"Care of the Newly Born Needs to Begin Prior to Birth and to Continue then After","authors":"A. Maheshwari, Rachana Singh, R. Christensen","doi":"10.5005/newborn-1-2-iv","DOIUrl":"https://doi.org/10.5005/newborn-1-2-iv","url":null,"abstract":"","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42798199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tasked for Compassion: Initiating Reproductive Grief Care in the Neonatal Intensive Care Unit","authors":"Kathryn R. Grauerholz","doi":"10.5005/jp-journals-11002-0026","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0026","url":null,"abstract":"","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44707751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk Prediction for Stillbirth and Neonatal Mortality in Low-resource Settings.","authors":"Vivek V Shukla, Waldemar A Carlo","doi":"10.5005/jp-journals-11002-0034","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0034","url":null,"abstract":"High stillbirth and neonatal mortality are major public health problems, particularly in low-resource settings in low- and middle-income countries (LMIC). Despite sustained efforts by national and international organizations over the last several decades, quality intrapartum and neonatal care is not universally available, especially in these low-resource settings. A few studies identify risk factors for adverse perinatal outcomes in low-resource settings in LMICs. This review highlights the evidence of risk prediction for stillbirth and neonatal death. Evidence using advanced machine-learning statistical models built on data from low-resource settings in LMICs suggests that the predictive accuracy for intrapartum stillbirth and neonatal mortality using prenatal and pre-delivery data is low. Models with delivery and post-delivery data have good predictive accuracy of the risk for neonatal mortality. Birth weight is the most important predictor of neonatal mortality. Further validation and testing of the models in other low-resource settings and subsequent development and testing of possible interventions could advance the field.","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":"1 2","pages":"215-218"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/75/a4/nihms-1822133.PMC9762612.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10474787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Maheshwari, Preeti Shakya, B. Adhikari, A. S. Nepal, Pragyik Pandey
{"title":"Rotavirus Infection in Neonates and Young Infants","authors":"A. Maheshwari, Preeti Shakya, B. Adhikari, A. S. Nepal, Pragyik Pandey","doi":"10.5005/jp-journals-11002-0014","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0014","url":null,"abstract":"Rotavirus is the primary cause of acute, frequently severe gastroenteritis among growing premature neonates, young infants, and children under the age of five globally. It contains a double-stranded ribonucleic acid genome is a member of the Reoviridae family. In this review, we have discussed the structure and characteristics of the virus, the pathogenesis of rotaviral diarrhea, clinical features, methods of diagnosis, clinical management, and available vaccines. This article combines peer-reviewed evidence from our own clinical studies with results of an extensive literature search in the databases PubMed, EMBASE, and Scopus.","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45790035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral Feeding of Preterm Infants in the NICU: Interventions and Outcomes","authors":"Leslie-Anne J. Dietrich, Cynthia Blanco","doi":"10.5005/jp-journals-11002-0010","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0010","url":null,"abstract":"","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43300480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Maheshwari, S. Viswanathan, K. McNelis, Zaineh Aja'Nini, Stephanie Merlino, Marissa Culver, M. Collin, Darlene Calhoun, Sharon Grow-Wargo
{"title":"Accretion Rates of Fat and Fat-free Mass in Infants at 30–45 weeks’ Postmenstrual Age","authors":"A. Maheshwari, S. Viswanathan, K. McNelis, Zaineh Aja'Nini, Stephanie Merlino, Marissa Culver, M. Collin, Darlene Calhoun, Sharon Grow-Wargo","doi":"10.5005/jp-journals-11002-0018","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0018","url":null,"abstract":"","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42178064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Low-lying Umbilical Venous Catheters are not Always Associated with Increased Complications","authors":"S. Joghee, M. Kamaluddeen, A. Soraisham","doi":"10.5005/jp-journals-11002-0004","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0004","url":null,"abstract":"Introduction: Umbilical venous catheters (UVCs) are frequently used for clinical care in neonatal intensive care units (NICUs). Umbilical venous catheters cannot always be positioned perfectly in the inferior vena cava, and low catheters have to be used until a more stable peripherally inserted central catheter can be placed after ruling-out early onset sepsis. There are concerns that low UVCs may be associated with complications such as infection, extravasation, and thrombosis. Objectives: To determine whether UVC complications were associated with (1) low positioning of the catheter tip and (2) the postnatal age at insertion. Methods: We examined a retrospective cohort of infants with UVCs in a tertiary NICU. Neonates with major congenital anomalies, hydrops fetalis, prenatally diagnosed cardiac arrhythmias, pericardial effusion, or ascites were excluded. The position of UVCs is considered as optimum if its tip is seen on radiographs at the level between 8th and 10th thoracic vertebrae (T8–T10), to be low if below T10, and high if above T8. The primary outcome was UVC-related complications resulting in early removal of catheter. We compared the rates of UVC-related complications resulting in removal of UVCs with tips in normal (T8–T10) vs low-lying (below T10) positions at the time of insertion. We also examined the impact of postnatal age, before or after 12 hours, and the frequency of the UVC-related complication. Results: Of the 919 eligible infants, UVC tips were located optimally in 433 (47%) and were low in 415 (45%). The UVC was positioned at an abnormally high position in 71 (8%) infants. Of the 919 infants, UVC-related complication was seen in 54 (5.9%) infants. Low-lying UVCs were removed due to complications in 27 of 415 (6.5%) compared with 20 of 433 (4.6%) optimally position catheters [adjusted odds ratio (aOR) = 1.16; 95% confidence interval (CI): (0.62–2.17)]. High-placed UVCs were associated with a higher rate of cardiac complications (aOR = 6.09, 95% CI [2.03–18.28]) compared with optimally position UVCs. There was also no difference in UVC-related complications between early and late insertion of UVC (6.3% vs 4.7%, p = 0.34). Conclusions: The frequency of complications and consequent need for removal did not differ in UVCs with a tip position traditionally perceived to be optimal or low or by the time of insertion after birth.","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49228966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Maheshwari, Rachana Singh, Ruben Vaidya, R. Ashwath
{"title":"Patent Ductus Arteriosus: A Diagnostic and Treatment Dilemma","authors":"A. Maheshwari, Rachana Singh, Ruben Vaidya, R. Ashwath","doi":"10.5005/jp-journals-11002-0023","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0023","url":null,"abstract":"Ductus arteriosus is a critically important vascular structure that functions as an extracardiac shunt in fetal life between the pulmonary and systemic circulations for optimal utilization of the placenta as a gas exchange organ and fetal well-being. While morbidities and mortality are well known to be associated with persistence of patent ductus arteriosus (PDA) in postnatal life, the treatment options have concerns for adverse outcomes. Additionally, high spontaneous closure rates, lack of clear definition of hemodynamically significant PDA (hs-PDA), ideal diagnostic tools, conflicting evidence regarding timing of treatment, and lack of clear benefits of PDA treatment from randomized trial in reducing adverse outcomes continue to pose challenges for clinicians managing preterm infants with PDA. This review focuses on the pathophysiology, current diagnostic and management practices, as well as the potential of utilizing unique diagnostic tools to support precision medicine for preterm infants with hs-PDA.","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45028824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}