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Hypoxic–Ischemic Encephalopathy: To Cool, or Not to Cool, That Is the Question 缺氧缺血性脑病:冷却，还是不冷却，这是一个问题
Newborn (Clarksville, Md.) Pub Date : 2022-10-07 DOI: 10.5005/jp-journals-11002-0037
S. Manzar, Ramachandra Bhat, Sheila Asghar, Rosario Riel–Romero, Nitin Walyat, Octavio Arevalo-Espejo, M. Mhanna
{"title":"Hypoxic–Ischemic Encephalopathy: To Cool, or Not to Cool, That Is the Question","authors":"S. Manzar, Ramachandra Bhat, Sheila Asghar, Rosario Riel–Romero, Nitin Walyat, Octavio Arevalo-Espejo, M. Mhanna","doi":"10.5005/jp-journals-11002-0037","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0037","url":null,"abstract":"","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44733216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Coordinated Multispecialty Care: A Need for Critically Ill Newborn Infants 协调多专科护理:危重新生儿的需要
Newborn (Clarksville, Md.) Pub Date : 2022-10-07 DOI: 10.5005/newborn-1-3-iv
A. Maheshwari, Rachana Singh, M. Motta
{"title":"Coordinated Multispecialty Care: A Need for Critically Ill Newborn Infants","authors":"A. Maheshwari, Rachana Singh, M. Motta","doi":"10.5005/newborn-1-3-iv","DOIUrl":"https://doi.org/10.5005/newborn-1-3-iv","url":null,"abstract":"","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42317987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Phylogeny, Ontogeny, and Organ-specific Differentiation of Macrophages in the Developing Intestine. 发育中肠道巨噬细胞的系统发育、个体发生和器官特异性分化。
Newborn (Clarksville, Md.) Pub Date : 2022-10-01 Epub Date: 2022-12-23 DOI: 10.5005/jp-journals-11002-0044
Akhil Maheshwari
{"title":"The Phylogeny, Ontogeny, and Organ-specific Differentiation of Macrophages in the Developing Intestine.","authors":"Akhil Maheshwari","doi":"10.5005/jp-journals-11002-0044","DOIUrl":"10.5005/jp-journals-11002-0044","url":null,"abstract":"<p><p>Macrophages are large highly motile phagocytic leukocytes that appear early during embryonic development and have been conserved during evolution. The developmental roles of macrophages were first described nearly a century ago, at about the time these cells were being identified as central effectors in phagocytosis and elimination of microbes. Since then, we have made considerable progress in understanding the development of various subsets of macrophages and the diverse roles these cells play in both physiology and disease. This article reviews the phylogeny and the ontogeny of macrophages with a particular focus on the gastrointestinal tract, and the role of these mucosal macrophages in immune surveillance, innate immunity, homeostasis, tissue remodeling, angiogenesis, and repair of damaged tissues. We also discuss the importance of these macrophages in the inflammatory changes in neonatal necrotizing enterocolitis (NEC). This article presents a combination of our own peer-reviewed clinical and preclinical studies, with an extensive review of the literature using the databases PubMed, EMBASE, and Scopus.</p>","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":"1 4","pages":"340-355"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/d4/nihms-1861230.PMC9872774.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10581676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enteroviral Infections in Infants. 婴儿肠道病毒感染。
Newborn (Clarksville, Md.) Pub Date : 2022-07-01 Epub Date: 2022-07-10 DOI: 10.5005/jp-journals-11002-0036
Srijan Singh, Sushant Satish Mane, Gangajal Kasniya, Sofia Cartaya, Mohd Mujibur Rahman, Akhil Maheshwari, Mario Motta, Pradeep Dudeja
{"title":"Enteroviral Infections in Infants.","authors":"Srijan Singh, Sushant Satish Mane, Gangajal Kasniya, Sofia Cartaya, Mohd Mujibur Rahman, Akhil Maheshwari, Mario Motta, Pradeep Dudeja","doi":"10.5005/jp-journals-11002-0036","DOIUrl":"10.5005/jp-journals-11002-0036","url":null,"abstract":"<p><p>Enteroviruses (EVs) are major pathogens in young infants. These viruses were traditionally classified into the following four subgenera: polio, coxsackie A and B, and echoviruses. Now that poliomyelitis seems to be controlled in most parts of the world, coxsackie and echoviruses are gaining more attention because (i) the structural and pathophysiological similarities and (ii) the consequent possibilities in translational medicine. Enteroviruses are transmitted mainly by oral and fecal-oral routes; the clinical manifestations include a viral prodrome including fever, feeding intolerance, and lethargy, which may be followed by exanthema; aseptic meningitis and encephalitis; pleurodynia; myopericarditis; and multi-system organ failure. Laboratory diagnosis is largely based on reverse transcriptase-polymerase chain reaction, cell culture, and serology. Prevention and treatment can be achieved using vaccination, and administration of immunoglobulins and antiviral drugs. In this article, we have reviewed the properties of these viruses, their clinical manifestations, and currently available methods of detection, treatment, and prognosis.</p>","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":"1 3","pages":"297-305"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e5/3c/nihms-1841449.PMC9599990.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10700825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Fresh-frozen Plasma in Newborn Infants. 新鲜冷冻血浆在新生儿中的应用。
Newborn (Clarksville, Md.) Pub Date : 2022-07-01 Epub Date: 2022-07-10 DOI: 10.5005/jp-journals-11002-0039
Manvi Tyagi, Akhil Maheshwari, Brunetta Guaragni, Mario Motta
{"title":"Use of Fresh-frozen Plasma in Newborn Infants.","authors":"Manvi Tyagi,&nbsp;Akhil Maheshwari,&nbsp;Brunetta Guaragni,&nbsp;Mario Motta","doi":"10.5005/jp-journals-11002-0039","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0039","url":null,"abstract":"<p><p>Nearly 10% of premature and critically ill infants receive fresh-frozen plasma (FFP) transfusions to reduce their high risk of bleeding. The authors have only limited data to identify relevant clinical predictors of bleeding and to evaluate the efficacy of FFP administration. There is still no consensus on the optimal use of FFP in infants who have abnormal coagulation parameters but are not having active bleeding. The aims of this review are to present current evidence derived from clinical studies focused on the use of FFP in neonatology and then use these data to propose best practice recommendations for the safety of neonates receiving FFP.</p>","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":"271-277"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/5d/nihms-1841448.PMC9631350.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40457785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital and Perinatal Varicella Infections. 先天性和围产期水痘感染。
Newborn (Clarksville, Md.) Pub Date : 2022-07-01 Epub Date: 2022-10-07 DOI: 10.5005/jp-journals-11002-0040
Srijan Singh, Akash Sharma, Mohammad Mozibur Rahman, Gangajal Kasniya, Akhil Maheshwari, Suresh B Boppana
{"title":"Congenital and Perinatal Varicella Infections.","authors":"Srijan Singh, Akash Sharma, Mohammad Mozibur Rahman, Gangajal Kasniya, Akhil Maheshwari, Suresh B Boppana","doi":"10.5005/jp-journals-11002-0040","DOIUrl":"10.5005/jp-journals-11002-0040","url":null,"abstract":"<p><p>Varicella-zoster virus (VZV) is a human pathogen of the α-herpesvirus family. Some fetuses infected in utero around 8-20 weeks of pregnancy show signs of congenital varicella syndrome (CVS). Infants born to mothers who develop varicella within 5 days before and 2 days after delivery can experience severe disease with increased mortality. The best diagnostic modality is polymerase chain reaction (PCR), which can be done using vesicular swabs or scrapings, scabs from crusted lesions, tissue from biopsy samples, and cerebrospinal fluid. The prevention and management of varicella infections include vaccination, anti-VZV immunoglobulin, and specific antiviral drugs. In this article, we have reviewed the characteristics of VZV, clinical manifestations, management of perinatal infections, and short- and long-term prognosis.</p>","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":"1 3","pages":"278-286"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/23/3f/nihms-1841450.PMC9762609.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10780616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neonatal Acute Liver Failure 新生儿急性肝衰竭
Newborn (Clarksville, Md.) Pub Date : 2022-06-29 DOI: 10.5005/jp-journals-11002-0029
Gurpreeti Grewal, H. Osiovich, R. Schreiber
{"title":"Neonatal Acute Liver Failure","authors":"Gurpreeti Grewal, H. Osiovich, R. Schreiber","doi":"10.5005/jp-journals-11002-0029","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0029","url":null,"abstract":"","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43314597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Major Chromosomal Abnormalities and Necrotizing Enterocolitis: Is there a Link? 主要染色体异常与坏死性小肠结肠炎：有联系吗？
Newborn (Clarksville, Md.) Pub Date : 2022-06-29 DOI: 10.5005/jp-journals-11002-0032
A. Maheshwari, T. Jilling
{"title":"Major Chromosomal Abnormalities and Necrotizing Enterocolitis: Is there a Link?","authors":"A. Maheshwari, T. Jilling","doi":"10.5005/jp-journals-11002-0032","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0032","url":null,"abstract":"","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42711077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Automated Cell Counter-derived Neutrophil Cell Population Data by VCS Technology as a Marker of Early-onset Neonatal Sepsis 用VCS技术检测早发新生儿败血症的自动细胞反源性中性粒细胞群体数据
Newborn (Clarksville, Md.) Pub Date : 2022-06-29 DOI: 10.5005/jp-journals-11002-0030
Francesco Morotti, Gilberto F Candela, G. Martellosio, F. Serana, M. Micheletti, D. Brugnoni, F. M. Risso, Mario Motta
{"title":"Automated Cell Counter-derived Neutrophil Cell Population Data by VCS Technology as a Marker of Early-onset Neonatal Sepsis","authors":"Francesco Morotti, Gilberto F Candela, G. Martellosio, F. Serana, M. Micheletti, D. Brugnoni, F. M. Risso, Mario Motta","doi":"10.5005/jp-journals-11002-0030","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0030","url":null,"abstract":"","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44966467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Approach to Neonatal Alloimmune Thrombocytopenia: The Perspective from a Transfusion Medicine Service 从输血医学角度探讨新生儿异免疫性血小板减少症
Newborn (Clarksville, Md.) Pub Date : 2022-06-29 DOI: 10.5005/jp-journals-11002-0031
A. Maheshwari, Greeshma Sharma, Ratti Ram Sharma
{"title":"Approach to Neonatal Alloimmune Thrombocytopenia: The Perspective from a Transfusion Medicine Service","authors":"A. Maheshwari, Greeshma Sharma, Ratti Ram Sharma","doi":"10.5005/jp-journals-11002-0031","DOIUrl":"https://doi.org/10.5005/jp-journals-11002-0031","url":null,"abstract":"","PeriodicalId":74306,"journal":{"name":"Newborn (Clarksville, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42403661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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