Neurocirugia (English Edition)最新文献

{"title":"Minimally invasive approach for skull base meningiomas","authors":"Carlos Roberto Vargas Gálvez,&nbsp;Omar López Arbolay,&nbsp;Marlon Manuel Ortiz Machín","doi":"10.1016/j.neucie.2023.11.002","DOIUrl":"10.1016/j.neucie.2023.11.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Skull base meningiomas constitute a complex group of skull base tumors. The endoscopic endonasal approaches (EEA) and endoscopic Keyhole have a minimally invasive philosophy with high effectiveness, safety, and a significant decrease in postoperative morbidity in these tumors.</p></div><div><h3>Objective</h3><p>To describe the results of the use of minimally invasive approaches to skull base meningiomas.</p></div><div><h3>Method</h3><p>A descriptive, retrospective study was carried out in 140 patients at the \"Hermanos Ameijeiras\" Hospital who underwent surgery for cranial base meningiomas using minimally invasive approaches to the cranial base. The degree of tumor resection, tumor recurrence, reinterventions, and complications were evaluated.</p></div><div><h3>Results</h3><p>ESA were used in 72.8% of the study, while endoscopic Keyholes were used in 26.4% and combined approaches in 0.7%. In relation to total tumor resection, 91.9% was generally achieved. Overall tumor recurrence and reinterventions were less than 8.5% and 4%, respectively. Complications in ESA were: cerebrospinal fluid (CSF) fistula (2.1%), diabetes insipidus, hydrocephalus, cerebral infarction, surgical site hematoma, worsening of cranial nerves I-IV (1.4%) respectively. While in the Keyhole type approaches: seizures (2.9%), hydrocephalus (1.4%), CSF fistula (1.4%), worsening of Nerves IX-XII (0.7%).</p></div><div><h3>Conclusions</h3><p>The following study reaffirms that minimally invasive approaches for skull base meningiomas constitute advanced surgical techniques for these tumors, associated with a low rate of postoperative complications.</p></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"35 3","pages":"Pages 127-135"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammatory pseudotumor, the great mimicker: A case report","authors":"María José Castelló Ruiz ,&nbsp;Ascensión Contreras Jimenez ,&nbsp;Iñigo Gorrostiaga Altuna ,&nbsp;Jose Masegosa Gonzalez","doi":"10.1016/j.neucie.2023.07.002","DOIUrl":"10.1016/j.neucie.2023.07.002","url":null,"abstract":"<div><p><span>Inflammatory pseudotumor<span> is a rare lesion, especially at the level of the central nervous system. Its etiology is unknown and the most accepted hypothesis is that it is the consequence of an exaggerated immune response. We present the clinical case of a young Senegalese male, with a history of epilepsy secondary to severe cranioencephalic trauma in childhood, who presented with new </span></span>epileptic seizures<span>. Imaging tests showed a lesion in the anterior fossa intimately attached to the meninges<span><span>, so the initial diagnosis was meningioma. A bifrontal craniotomy and </span>microsurgical excision were performed. The definitive anatomopathological analysis concluded that the lesion is an inflammatory pseudotumor whose origin is secondary to a disproportionate reparative process after cranioencephalic trauma.</span></span></p></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"35 3","pages":"Pages 164-168"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10194191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of third ventricle volumetry in patients with normal pressure hydrocephalus","authors":"Herbert Daniel Jiméne Zapata,&nbsp;Adrián Fernández García,&nbsp;Carla Timisoara Amilburu Sáenz,&nbsp;Carlos Alberto Rodríguez Arias","doi":"10.1016/j.neucie.2023.10.004","DOIUrl":"10.1016/j.neucie.2023.10.004","url":null,"abstract":"<div><h3>Objective</h3><p>To use third ventricle morphometric variables as a tool for the selection of patients with idiopathic normal pressure hydrocephalus (iNPH) who are candidates for ventriculoperitoneal shunts (VPS).</p></div><div><h3>Material and methods</h3><p>Retrospective study enrolling patients with iNPH. Katzman infusion test was performed and a Rout &gt; 12 mmHg/mL/min was considered a positive result. The transverse diameter and the volume of the third ventricle were measured in the preoperative MRI. Postoperative improvement was assessed with the NPH score. The results were analysed with SPSS software.</p></div><div><h3>Results</h3><p>52 patients with a mean age of 76 years were analysed. There was no difference in the diameter of the third ventricle among patients with a positive result and those with a negative result in the infusion test (12.28 vs 11.68 mm; <em>p</em> = 0.14). Neither were difference detected in the ventricle volume of both groups (3.6 vs 3.5cc; <em>p</em> = 0.66). Those patients who improved after VPS had a smaller third ventricle compared to those who did not respond after surgery (11.85 mm vs. 12.96 mm; <em>p</em> = 0.009). Diameter and volume of third ventricle present a significant strong correlation (Pearson correlation coefficient = 0.72; <em>p</em> &lt; 0.0001).</p></div><div><h3>Conclusion</h3><p>Morphometric variables of third ventricle may be useful in predicting a good response to VPS in patients with idiopathic normal pressure hydrocephalus.</p></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"35 3","pages":"Pages 122-126"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139682118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Olivary body exposure through far lateral and lower retrosigmoid approaches. Comparative analysis of the exposed surface and angle of attack","authors":"Pau Capilla-Guasch ,&nbsp;Vicent Quilis-Quesada ,&nbsp;Félix Pastor-Escartín ,&nbsp;Diego Tabarés Palacín ,&nbsp;Juan Pablo Valencia Salazar ,&nbsp;José M. González-Darder","doi":"10.1016/j.neucie.2023.08.001","DOIUrl":"10.1016/j.neucie.2023.08.001","url":null,"abstract":"<div><h3>Objectives</h3><p>Throughout neurosurgical history, the treatment of intrinsic lesions located in the brainstem has been subject of much controversy. The brainstem is the anatomical structure of the central nervous system (CNS) that presents the highest concentration of nuclei and fibers, and its simple manipulation can lead to significant morbidity and mortality. Once one of the safe entry points at the medulla oblongata has been established, we wanted to evaluate the safest approach to the olivary body (the most used safe entry zone on the anterolateral surface of the medulla oblongata). The proposed objective was to evaluate the working channel from the surface of each of the far lateral and retrosigmoid approaches to the olivary body: distances, angles of attack and channel content.</p></div><div><h3>Material and methods</h3><p>To complete this work, a total of 10 heads injected with red/blue silicone were used. A total of 40 approaches were made in the 10 heads used (20 retrosigmoid and 20 far lateral). After completing the anatomical study and obtaining the data referring to all the approaches performed, it was decided to expand the sample of this research study by using 30 high-definition magnetic resonance imaging of anonymous patients without cranial or cerebral pathology. The reference points used were the same ones defined in the anatomical study. After defining the working channels in each of the approaches, the working distances, angle of attack, exposed surface, and the number of neurovascular structures present in the central trajectory were analyzed.</p></div><div><h3>Results</h3><p>The distances to the cranial and medial region of the olivary body were 52.71 mm (SD 3.59) from the retrosigmoid approach and 27.94 mm (SD 3.99) from the far lateral; to the most basal region of the olivary body, the distances were 49.93 (SD 3.72) from the retrosigmoid approach and 18.1 mm (SD 2.5) from the far lateral. The angle of attack to the caudal region was 19.44° (SD 1.3) for the retrosigmoid approach and 50.97° (SD 8.01) for the far lateral approach; the angle of attack to the cranial region was 20.3° (SD 1.22) for the retrosigmoid and 39.9° (SD 5.12) for the far lateral. Regarding neurovascular structures, the probability of finding an arterial structure is higher for the lateral far, whereas a neural structure will be more likely from a retrosigmoid approach.</p></div><div><h3>Conclusions</h3><p>As conclusions of this work, we can say that far lateral approach presents more favorable conditions for the microsurgical treatment of intrinsic bulbar and bulbomedullary lesions approached through the caudal half of the olivary body. In those cases of bulbar and pontine-bulbar lesions approached through the cranial half of the olivary body, the retrosigmoid approach can be considered for selected cases.</p></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"35 3","pages":"Pages 152-163"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139513336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aneurysmal subarachnoid haemorrhage: Volumetric quantification of the blood distribution pattern to accurately predict the ruptured aneurysm location","authors":"Alejandra Mosteiro ,&nbsp;Diego Culebras ,&nbsp;Alberto Vargas Solano ,&nbsp;Javier Luis Moreno Negrete ,&nbsp;Antonio López-Rueda ,&nbsp;Laura Llull ,&nbsp;Daniel Santana ,&nbsp;Leire Pedrosa ,&nbsp;Sergio Amaro ,&nbsp;Ramón Torné ,&nbsp;Joaquim Enseñat","doi":"10.1016/j.neucie.2023.12.002","DOIUrl":"10.1016/j.neucie.2023.12.002","url":null,"abstract":"<div><h3>Background</h3><p><span>In spontaneous subarachnoid haemorrhage<span> (SAH) accurate determination of the bleeding source is paramount to guide treatment. Traditionally, the bleeding pattern has been used to predict the aneurysm location. Here, we have tested a software-based tool, which quantifies the volume of intracranial blood and stratifies it according to the regional distribution, to predict the location of the </span></span>ruptured aneurysm.</p></div><div><h3>Methods</h3><p>A consecutive series of SAH patients admitted to a single tertiary centre between 2012–2018, within 72 h of onset, harbouring a single intracranial aneurysm. A semi-automatized method of blood quantification, based on the relative density increase, was applied to initial non-contrast CTs. Five regions were used to define the bleeding patterns and to correlate them with aneurysm location: perimesencephalic, interhemispheric, right/left hemisphere and intraventricular.</p></div><div><h3>Results</h3><p><span><span>68 patients were included for analysis. There was a strong association between the distribution of blood and the aneurysm location (p &lt; 0.001). In particular: ACom and interhemispheric fissure (p &lt; 0.001), MCA and ipsilateral hemisphere (p &lt; 0.001), ICA and ipsilateral hemisphere and perimesencephalic cisterns (p &lt; 0.001), </span>PCom and hemispheric, perimesencephalic and intraventricular (p = 0.019), and </span>PICA and perimesencephalic and intraventricular (p &lt; 0.001). The internal diagnostic value was high (AUROC ≥ 0.900) for these locations.</p></div><div><h3>Conclusion</h3><p>Regional automatised volumetry<span> seems a reliable and objective tool to quantify and describe the distribution of blood within the subarachnoid spaces. This tool accurately predicts the location of the ruptured aneurysm; its use may be prospectively considered in the emergency setting when speed and simplicity are attained.</span></p></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"35 3","pages":"Pages 136-144"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139076144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of epidural infiltration in the management of pain and disability due to acute and subacute lumbosacral radiculopathy","authors":"Jose Manuel Rabanal Llevot ,&nbsp;Amaia Muñoz Alonso ,&nbsp;Alberto Taborga Echevarría ,&nbsp;Jose Angel Martínez Agueros ,&nbsp;Sergio Maldonado Vega","doi":"10.1016/j.neucie.2023.07.008","DOIUrl":"10.1016/j.neucie.2023.07.008","url":null,"abstract":"<div><h3>Background and Objective</h3><p><span>Epidural infiltrations<span> are used for treatment<span> of low back pain and sciatica. Linked to lumbar </span></span></span>radiculopathy (lumbosacral radicular syndrome). This study evaluates the efficacy of epidural infiltration by different routes to reduce pain intensity, disability and return to work.</p></div><div><h3>Methods</h3><p>Is a prospective observational study in one hundred consecutive patients sent to pain unit for severe lumbo-sacral radiculopaty. We analyze the efficacy on pain relief (Visual Analogue Scale) and funcional status at two weeks, one month, and three months after epidural injection of local anesthetics and esteroids with differents approachs (interlaminar, caudal and transforaminal).</p></div><div><h3>Results</h3><p>Ninety nine patients (46.5% men, 53.5 women) were finally enrrolled in the study. Mean age was 57.47 ± 11.1 years. The caudal approach was used in 58.6% patients, 23.2% transforaminal approach, and 18.2% interlaminar approach. A significant pain relief was found in all times studied (EAV 7.48 ± 1.5 basal; 6.2 ± 0,9 at 15 days; 6.3 ± 1.2 at one month; 6.15 ± 1.3 at 3 months, p &lt; 0.05). Transforaminal approach was superior to caudal or interlaminal. Seventy percent in time off work patients returned to work after epidural inyections.</p></div><div><h3>Conclusions</h3><p>Epidural local anesthetics with esteroids injections for lumbo-sacral radiculopathy were effective for low back pain, improved functional status and promoted return to work. Transforaminal approach is superior to others.</p></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"35 2","pages":"Pages 64-70"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41222844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-term outcomes after selective shunt during carotid endarterectomy: a propensity score matching analysis","authors":"Juliana Pereira-Macedo ,&nbsp;Luís Duarte-Gamas ,&nbsp;António Pereira-Neves ,&nbsp;José José Paulo de Andrade ,&nbsp;João Rocha-Neves","doi":"10.1016/j.neucie.2023.07.006","DOIUrl":"10.1016/j.neucie.2023.07.006","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Carotid cross-clamping during carotid endarterectomy<span> might lead to intraoperative neurologic deficits, increasing stroke/death risk. If deficits are detected, carotid shunting has been recommended to reduce the risk of stroke. However, shunting may sustain a specific chance of embolic events and subsequently incurring harm. Current evidence is still questionable regarding its clear benefit. The aim is to determine whether a policy of selective shunt impacts the complication rate following an endarterectomy.</span></p></div><div><h3>Material and methods</h3><p><span>From January 2013 to May 2021, all patients undergoing carotid endarterectomy under regional anesthesia with intraoperative neurologic alteration were retrieved. Patients submitted to selective shunt were compared to a non-shunt group. A 1:1 </span>propensity score matching<span> (PSM) was performed. Differences between the groups and clinical outcomes were calculated, resorting to univariate analysis.</span></p></div><div><h3>Results</h3><p>Ninety-eight patients were selected, from which 23 were operated on using a shunt. After PSM, 22 non-shunt patients were compared to 22 matched shunted patients. Concerning demographics and comorbidities, both groups were comparable to pre and post-PSM, except for chronic heart failure, which was more prevalent in shunted patients (26.1%, P<!--> <!-->=<!--> <!-->0.036) in pre-PSM analysis. Regarding 30-day stroke and score Clavien–Dindo ≥2, no significant association was found (P<!--> <!-->=<!--> <!-->0.730, P<!--> <!-->=<!--> <!-->0.635 and P<!--> <!-->=<!--> <!-->0.942, P<!--> <!-->=<!--> <!-->0.472, correspondingly, for pre and post-PSM).</p></div><div><h3>Conclusions</h3><p>In this cohort, resorting to shunting did not demonstrate an advantage regarding 30-day stroke or a Clavien–Dindo ≥ 2 rates. Nevertheless, additional more extensive studies are mandatory to achieve precise results concerning the accurate utility of carotid shunting in this subset of patients under regional anesthesia.</p></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"35 2","pages":"Pages 71-78"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10238162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intracerebral hemorrhage after deep brain stimulation surgery guided with microelectrode recording: analysis of 297 procedures","authors":"Beatriz Dos Santos ,&nbsp;Rui Vaz ,&nbsp;Ana Cristina Braga ,&nbsp;Manuel Rito ,&nbsp;Diana Lucas ,&nbsp;Clara Chamadoira","doi":"10.1016/j.neucie.2023.09.001","DOIUrl":"10.1016/j.neucie.2023.09.001","url":null,"abstract":"<div><h3>Objectives</h3><p><span>Report the incidence of symptomatic and asymptomatic intracerebral hemorrhage (ICH) </span>in patients<span> submitted to deep brain stimulation<span> (DBS) guided with microelectrode recording (MER) with further analysis of potential risk factors, both inherent to the patient and related to the pathology and surgical technique.</span></span></p></div><div><h3>Methods</h3><p><span>We performed a retrospective observational study. 297 DBS procedures were concluded in 277 patients in a single hospital centre between January 2010 and December 2020. All surgeries were guided with MER. We analysed the incidence of symptomatic and asymptomatic ICH and its correlation to age, sex, diagnosis, hypertension and perioperative hypertension, diabetes, dyslipidaemia, </span>antiplatelet drugs, anatomic target, and number of MER trajectories.</p></div><div><h3>Results</h3><p>There were a total of 585 electrodes implanted in 277 patients. 16 ICH were observed, of which 6 were symptomatic and 10 asymptomatic, none of which incurred in permanent neurological deficit. The location of the hemorrhage varied between cortical and subcortical plans, always in relation with the trajectory or the final position of the electrode. The incidence of symptomatic ICH <em>per</em> lead-implantation was 1%, and the CT-scan demonstrated asymptomatic ICH in 1.7% more patients. Male patients or with hypertension are 2.7 and 2.2 times more likely to develop ICH, respectively. However, none of these characteristics has been shown to have a statistically significant association with the occurrence of ICH, as well as age, diagnosis, diabetes, dyslipidaemia, antiplatelet drugs, anatomic target, number of MER trajectories and perioperative hypertension.</p></div><div><h3>Conclusions</h3><p>MER-guided DBS is a safe technique, with low incidence of ICH and no permanent deficits in our study. Hypertension and male sex seem to be risk factors for the development of ICH in this surgery. Nevertheless, no statistically significant factors were found for the occurrence of this complication.</p></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"35 2","pages":"Pages 79-86"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49685862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous CSF fistula as a manifestation of idiopathic intracranial hypertension","authors":"Samsara López Hernández ,&nbsp;Carlos Alberto Rodríguez Arias ,&nbsp;Jaime Santos Pérez ,&nbsp;Mario Martínez-Galdámez ,&nbsp;Adrián Fernández García ,&nbsp;Herbert Daniel Jiménez Zapata","doi":"10.1016/j.neucie.2023.02.002","DOIUrl":"10.1016/j.neucie.2023.02.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Spontaneous cerebrospinal fluid (CSF) fistula, of unknown origin, is a rare condition whose aetiology is increasingly related to idiopathic intracranial hypertension<span> (IIH). This study tries to raise awareness that they should not be considered as two different processes, but that fistulas<span> can be a form of debut, requiring a study and subsequent treatment. Repair techniques are described, as well as the study of HII.</span></span></p></div><div><h3>Results</h3><p><span><span>We treated 8 patients, 5 women and three men, aged between 46 and 72 years, with a diagnosis of spontaneous CSF fistula, four nasal and four otics who underwent surgical treatment. After repair, a diagnostic study was performed for IIH by MRI and Angio-MRI, presenting in all cases a </span>transverse venous sinus<span><span> stenosis. The intracranial pressure values obtained by </span>lumbar puncture showed values of 20</span></span> <!-->mm Hg or higher. All patients were diagnosed with HII. The one-year follow-up did not reveal any recurrence of the fistulas, maintaining a control of the HII.</p></div><div><h3>Conclusion</h3><p>Despite their low frequency of both cranial CSF fistula and IIH, an association of both conditions should be considered by continuing the study and surveillance of these patients after fistula closure.</p></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"35 2","pages":"Pages 57-63"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9679251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lateral-type posterior fossa ependymomas in pediatric population","authors":"Pablo Miranda-Lloret,&nbsp;Estela Plaza-Ramírez,&nbsp;Juan Antonio Simal-Julián,&nbsp;Giovanni Pancucci,&nbsp;Adela Cañete,&nbsp;Alejandro Montoya-Filardi,&nbsp;Gemma Llavador","doi":"10.1016/j.neucie.2023.10.001","DOIUrl":"10.1016/j.neucie.2023.10.001","url":null,"abstract":"<div><h3>Background</h3><p>Lateral-type posterior fossa<span> ependymomas are a well-defined subtype of tumours both clinically and pathologically, with a poor prognosis. Their incidence is low and surgical management is challenging. The objective of the present work is to review our series of lateral-tye posterior fossa ependymomas and compare our results with those of previous series.</span></p></div><div><h3>Methods</h3><p>Among 30 cases of ependymoma operated in our paediatric department in the last ten years, we identified seven cases of lateral-type posterior fossa ependymomas. We then performed a retrospective, descriptive study.</p></div><div><h3>Results</h3><p>Mean age of our patients was 3.75 years. 6 cases presented with hydrocephalus<span>. Mean tumour volume at diagnosis was 61 cc. A complete resection was achieved in six cases and a near-total resection in one patient. 5 patients transiently required a gastrostomy<span><span> and a tracheostomy. Mean follow-up was 58 months. One case progressed along this period and eventually died. 4 cases of hydrocephalus required a ventriculoperitoneal </span>CSF shunt<span> and two were managed with a third ventriculostomy. At last follow-up 4 patients carried a normal life and two displayed a mild restriction according to Lansky´s scale.</span></span></span></p></div><div><h3>Conclusions</h3><p>The aim of surgical treatment in lateral-type posterior fossa ependymomas is complete resection. Neurological deficits associated to lower cranial nerve dysfunction are common but transient. Deeper genetic characterization of these tumours may identify risk factors that guide stratification of adjuvant therapies.</p></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"35 2","pages":"Pages 87-94"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139513277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}