Neurocirugia (English Edition)最新文献

{"title":"Global trends in neurosurgical research: Insights from the top 100 most-cited articles.","authors":"Roser Garcia-Armengol, Sebastian Andres Menéndez-Girón, Cristina Hostalot, Ana Cristina Pérez-Balaguero, Carlos Javier Dominguez, Ana Rodriguez-Hernandez","doi":"10.1016/j.neucie.2025.500656","DOIUrl":"10.1016/j.neucie.2025.500656","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to identify and analyze the 100 most-cited articles in neurosurgical journals over the past 20 years.</p><p><strong>Methods: </strong>The Thomson Reuters Web of Science citation index was used to analyze articles from high-impact neurosurgical journals identified via Journal Citation Reports. Data extracted included citations, citations per year, title, authors, year, country, institution, journal, study type, and thematic area. Citation analysis identified the most impactful articles. A bibliometric analysis compared trends between 2012-2022 and 2001-2011. Descriptive statistics and Pearson correlation were applied to examine the relationship between publication year and citation count. Stata V14.2 was used for statistical analysis.</p><p><strong>Results: </strong>Citations for the top 100 articles ranged from 194 to 1,501. \"Journal of Neurosurgery\" and \"Neurosurgery\" published the most-cited articles, with peak productivity in 2012 and 2013. The USA was the leading country in article contributions. Neuro-oncology, especially tumor studies, was the dominant thematic field.</p><p><strong>Conclusions: </strong>The bibliometric analysis highlighted a strong centralization in neurosurgical research, with most highly cited articles coming from two major journals, largely from the United States. This reveals the significant influence of a few key contributors in global neurosurgery.</p>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":" ","pages":"500656"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cauda equina malignant peripheral nerve sheath tumor presenting with subarachnoid hemorrhage: a case report","authors":"Rafael Aponte-Caballero ,&nbsp;Julian Alfonso Sierra-Peña ,&nbsp;Juan Felipe Abaunza-Camacho ,&nbsp;William Mauricio Riveros-Castillo ,&nbsp;Javier M. Saavedra","doi":"10.1016/j.neucie.2024.10.001","DOIUrl":"10.1016/j.neucie.2024.10.001","url":null,"abstract":"<div><div>Malignant peripheral nerve sheath tumors (MPNST) are uncommon aggressive neoplasms, frequently associated with type I neurofibromatosis. This is the first case of intradural lumbar spine MPNST with intraoperative findings of associated subarachnoid hemorrhage (SAH). A 72-year-old man presented to the emergency department with severe acute low back pain. Neurological examination was unremarkable. Gadolinium-enhanced MRI of the lumbar spine showed an irregularly shaped intradural lesion extending from L3 to L5. The lesion exhibited a medium signal both on T1 and T2-weighted imaging with peripheral enhancement. Through an L3-L5 laminectomy, a diffuse SAH, and a tumor tightly adherent to cauda equina nerve roots were found. Specimen examination revealed a fusocelular tumor with pleomorphic and hyperchromatic nuclei, positive for S100, and SOX10. On an 8-month follow-up, he had no neurological deficit, with a Karnofsky performance score of 90 points. Surgical evidence of SAH in lumbar spine intradural MPNST is a novel finding.</div></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"36 2","pages":"Pages 129-134"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute subdural hematoma from ruptured middle cerebral artery aneurysm: A rare and critical analysis of 25 cases","authors":"Cristina Romero-López ,&nbsp;Javier Ros de San Pedro ,&nbsp;Francisco Arteaga-Romero ,&nbsp;Beatriz Cuartero-Pérez ,&nbsp;Ignacio Martín-Schrader","doi":"10.1016/j.neucie.2024.11.002","DOIUrl":"10.1016/j.neucie.2024.11.002","url":null,"abstract":"<div><h3>Background</h3><div>An acute subdural hematoma (aSDH) is a rare presentation of a ruptured intracranial aneurysm with pathophysiology and prognosis poorly defined. According to literature, prognosis might be improved with prompt diagnosis, hematoma evacuation and aneurysm treatment. The objective is to specify pathophysiology, prognostic factors and management of this pathology.</div></div><div><h3>Methods</h3><div>We reported 23 cases of aSDH due to ruptured MCA aneurysm from literature revision and 2 cases from our center.</div></div><div><h3>Results</h3><div>Median age was 51 years and 48% (12/25) were females. At their arrival, 76% (19/25) presented decreased level of consciousness and 55.55% (10/18) neurological deficits. Aneurysmal location was left MCA in 57.14% (8/14) and MCA segments were M4 in 76.92% (10/13) and bifurcation in 23.07% (3/13), median aneurysmal size was 6 mm, median hematoma size was 10 mm, median midline shift was 9 mm, aneurysmal projection and MCA concavity were anterior in 100% (3/3), subarachnoid hemorrhage (SAH) was present in 52.17% (12/23). The treatment was surgery in 84% (21/25), endovascular in 12% (3/25) and in 20% (5/25) decompressive craniectomy (DC) was necessary. Glasgow Outcome Scale (GOS) was &gt;3/favorable in 66.66% (16/24) and death in 16.66% (4/2).</div></div><div><h3>Conclusions</h3><div>Anterior MCA concavity and aneurysmal projection might be related with aSDH presentation in proximal MCA aneurysms. We should suspect aneurysm origin when there is no history or stigma of trauma, and CT shows disproportionately massive aSDH. Hematoma evacuation solves the compressive mechanism which is the main cause of neurological deterioration in pure aSDH cases, because of that, immediate hematoma evacuation could justify better outcome in these patients.</div></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"36 2","pages":"Pages 83-92"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lateralization in visualization among neurosurgeons","authors":"Hrvoje Barić ,&nbsp;Sara Komljenović ,&nbsp;Helena Ljulj","doi":"10.1016/j.neucie.2024.11.003","DOIUrl":"10.1016/j.neucie.2024.11.003","url":null,"abstract":"<div><h3>Background</h3><div>Handedness is an epiphenomenon of brain lateralization which has been researched in the context of surgical performance, yet the same does not hold true for lateralization at a more fundamental level. We aimed to investigate whether neurosurgeons are biased in visualizing and depicting anatomy and pathology.</div></div><div><h3>Methods</h3><div>This was a two part study consisting of an online survey and image analysis. An online questionnaire was used to collect basic sociodemographic data and prompt subjects to visualize surgical approaches and pathological entities and report on the side of the visualized topics. Prominent neurosurgical literature was screened for depictions of the same entities and approaches and the depicted side was noted.</div></div><div><h3>Results</h3><div>There were 49 responses, most from Croatia (n = 26), men (n = 38), right-handed (n = 42), of average age 37 years, and with 9 years of neurosurgical experience. Ambidexterity was more prevalent than in the general population. The respondents imagined the right side more commonly in all cranial-related questions, and the left side in spine-related questions. Images in neurosurgical literature showed correspondingly biased laterality.</div></div><div><h3>Conclusion</h3><div>There is a significant bias among neurosurgeons in laterality in processing topographical information on anatomy and pathology. Research is warranted to investigate the causes and real life implications of this phenomenon.</div></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"36 2","pages":"Pages 93-97"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endothelial dysfunction and vascular abnormalities in acromegaly. A case report","authors":"Ana Irigaray Echarri ,&nbsp;M. Dolores Ollero García-Agulló ,&nbsp;José Jorge Ortez Toro ,&nbsp;Idoya Zazpe Cenoz","doi":"10.1016/j.neucie.2024.10.005","DOIUrl":"10.1016/j.neucie.2024.10.005","url":null,"abstract":"<div><div>In patients with acromegaly, the pleiotropic effects of GH and IGF-1 have been associated with the development of endothelial dysfunction and vascular abnormalities.</div><div>We present the case of a 45-year-old male diagnosed with acromegaly. Magnetic resonance imaging identified a marked dilatation and medialization of both cavernous internal carotid arteries (ICA), leading to a narrow intercarotid distance, a phenomenon known as “carotid kisses”.</div><div>This vascular alteration has been described in greater proportion in patients with acromegaly. The anomalies that are also present with greater prevalence in these patients are: aneurysms of the ICA, protrusion of the ICA into the sphenoid sinus, narrow intercarotid distance, fusiform dilatation of the ICA and dehiscence of this artery in the bony canal. The presence of such alterations increases the risk of injury to the ICA.</div><div>Pre-surgical detection of such abnormalities is essential to ensure the safety of the surgical approach.</div></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"36 2","pages":"Pages 135-138"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is anterior fusion still necessary in patients with neurologically intact thoracolumbar burst fractures? A systematic review and meta-analysis","authors":"Andrey Grin,&nbsp;Vasily Karanadze,&nbsp;Ivan Lvov ,&nbsp;Aleksandr Talypov,&nbsp;Anton Kordonskiy,&nbsp;Rinat Abdrafiev","doi":"10.1016/j.neucie.2024.11.006","DOIUrl":"10.1016/j.neucie.2024.11.006","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objectives&lt;/h3&gt;&lt;div&gt;To conduct a systematic review and single-arm meta-analysis to evaluate and compare radiological indicators, as well as short-term and long-term outcomes, in patients with neurologically intact thoracolumbar burst fractures (TLBF) who underwent anterior fusion, combined anterior-posterior procedure, or short-segment pedicle screw fixation (PSF).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;A systematic review following PRISMA guidelines was conducted. Inclusion criteria comprised articles published between 2004 and 2023, full-text availability in English, burst fractures without spinal cord or nerve root injuries at admission, short-segment PSF without fusion, anterior or combined fusion methods, patients aged 18 or older, and a minimum 12-month follow-up.&lt;/div&gt;&lt;div&gt;Meta-analysis was carried out using Comprehensive Meta-Analysis software. Using a single-arm meta-analysis method, pooled indicators of short- and long-term outcomes for each studied group were determined. The obtained data were then compared using simple comparison.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The pooled mean Cobb angle at admission for the anterior, combined, and PSF groups was 18.2° (95% CI, 14.6−21.8), 11.7° (95% CI, 9.7−13.5), and 17.1° (95% CI, 15.1–19.1), respectively. Anterior fusion achieved a greater degree of kyphosis correction across all groups, but only the combined group showed a nonsignificant loss of correction after discharge (SMD = 0.809 [95% CI, 0.270, 1.348]). The anterior vertebral body compression rate at admission was 55.2% (95% CI, 46.3−64.0) in the combined group and 37.8% (95% CI, 33.7−41.9) in the PSF group.&lt;/div&gt;&lt;div&gt;Operative time, blood loss, and hospitalization duration were lowest in the percutaneous PSF group, with means of 96.5 min (95% CI, 82.4–110.6), 83.8 ml (95% CI, 71.7–95.9), and 6.6 days (95% CI, 4.7–8.5), respectively. All techniques demonstrated a similar incidence of deep wound infections and implant-related complications.&lt;/div&gt;&lt;div&gt;The pooled Oswestry Disability Index (ODI) scores were 17.2 (95% CI, 10.4−23.9) for the anterior group, 15.4 (95% CI, 11.5–19.3) for the combined group, and 13.4 (95% CI, 10.4–16.3) for the PSF group.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;For patients with neurologically intact thoracolumbar burst fractures, with a kyphotic angle of less than 19.1° and an anterior vertebral body compression rate of less than 41.9%, short-segment pedicle screw fixation without fusion may be preferable option due to reduced intraoperative blood loss, shorter operation duration, shorter hospital stay, and better ODI scores at final follow-up. Routine anterior fusion has demonstrated high potential for kyphosis correction. The loss of the Cobb angle from surgery to final follow-up was nonsignificant only in patients who underwent combined surgery. When determining the surgical approach, surgeons should carefully weigh the advantages of anterior and combined fusion against the significantly higher sur","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"36 2","pages":"Pages 112-128"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of clinical efficacy of MMA embolization combined with subdural perforation drainage and subdural perforation drainage in the treatment of CSDH","authors":"Wen Cheng,&nbsp;Quanlong Yang,&nbsp;Xiaodong Yuan,&nbsp;Jiangbin Wu","doi":"10.1016/j.neucie.2024.11.001","DOIUrl":"10.1016/j.neucie.2024.11.001","url":null,"abstract":"<div><h3>Background</h3><div>Chronic subdural hematoma is a frequent neurosurgical illness, and current treatment options mostly include subdural trepanation and drainage alone, as well as middle meningeal artery embolization in conjunction with subdural trepanation and drainage. However, there is currently a lack of extensive study and data support for comparing the clinical results of the two surgical treatment techniques.</div></div><div><h3>Objective</h3><div>The goal of this study is to compare the clinical effects of middle meningeal artery embolization combined with subdural trepanation and drainage versus simple subdural trepanation and drainage in the treatment of chronic subdural hematoma, in order to provide a reliable foundation for clinical selection of appropriate surgical treatment methods.</div></div><div><h3>Methods</h3><div>This study included 71 patients with chronic subdural hematoma, who were divided into two groups according to the procedure: observation group (n = 25) and control group (n = 46). The control group received only basic subdural drilling and drainage.</div></div><div><h3>Conclusions</h3><div>This study found that MMA embolization combined with subdural trepanation and drainage provides a greater therapeutic benefit in the treatment of chronic subdural hematoma. The observation group outperformed the control group in terms of postoperative CT results, Barthel index, and clinical effect, as well as operating time. Furthermore, the observation group's complications and recurrence rate were much lower than the control group’s.</div></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"36 2","pages":"Pages 75-82"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report on a late diagnosis of pilocytic astrocytoma in a Dandy–Walker complex","authors":"Juan Sebastián Solis-Mata ,&nbsp;Fernando Castro-Soto ,&nbsp;José Alfonso Alvarez-Castro ,&nbsp;Sonia Iliana Mejía-Pérez","doi":"10.1016/j.neucie.2024.10.007","DOIUrl":"10.1016/j.neucie.2024.10.007","url":null,"abstract":"<div><div>Dandy–Walker malformation (DWM) and pilocytic astrocytoma are entities that manifest themselves at an early age. DWM is a cerebella type associated with several anatomical changes. Very few cases of concomitant occurrence of DWM and pilocytic astrocytoma have been reported on the literature. Male 20 years old, clinical history of 6 months of evolution with nausea, dizziness, headache, photophobia, phonofobia, vomiting, walking laterality, diplopia, tonic–clonic seizures, nystagmus, dysmetria, and dysdiadochokinesia. Cranial tomography was performed, reporting hydrocephaly data with significant dilation of the IV ventricle and the presence of a tumor lesion in the posterior fossa of the right cerebellar hemisphere. Pediatric tumors that manifest in adulthood are rare, with signs such as intracranial hypertension and compress the cranial nerves. The prognosis will be determined by the accompanying abnormalities as well as the effectiveness of the appropriate treatment.</div></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"36 2","pages":"Pages 139-143"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolomic markers of electrolytes, gases and internal environment of the content of chronic subdural hematomas","authors":"Angel Jesús Lacerda-Gallardo ,&nbsp;Daisy Abreu-Pérez ,&nbsp;Miguel de Jesús Mazorra Pazo ,&nbsp;Jose Antonio Galvez","doi":"10.1016/j.neucie.2024.12.004","DOIUrl":"10.1016/j.neucie.2024.12.004","url":null,"abstract":"<div><h3>Background and objective</h3><div>Chronic subdural hematoma is one of the most common diseases in neurosurgical practice. The content of electrolytes and gases in the collection could participate in the growth and expansion mechanism, however, there is no evidence that they have been studied before. The objective has been to identify electrolyte, gas and internal metabolomic markers of the content of chronic subdural hematomas, with the possibility of participating in their growth and expansion and to substantiate a pathophysiological hypothesis that interacts with existing ones.</div></div><div><h3>Material and method</h3><div>A descriptive study was carried out with 53 patients operated on for chronic subdural hematoma, at the “Roberto Rodríguez Fernández” General Teaching Hospital of Morón in Ciego de Ávila, Cuba, in the period between January 2019 and December 2023. The diagnoses were obtained with computed axial tomography. The electrolyte and blood gas components of hematomas are correlated with clinical and neuroimaging variables.</div></div><div><h3>Results</h3><div>Patients over 70 years of age predominated, 37 (69.81%) and males 38 (71.70%). The Markwalder scale upon admission showed a predominance of Grade III in 24 cases (45.28%). The Glasgow outcome scale showed a predominance of Grade V, 31 (58.49%).</div></div><div><h3>Conclusions</h3><div>Electrolyte and gasometric metabolomic markers of subdural blood can promote the phenomenon of progressive growth and expansion and have a synergistic effect with the rest of the pathophysiological mechanisms.</div></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"36 2","pages":"Pages 104-111"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between NLR (Neutrophil/Lymphocyte ratio) value and clinical outcome in patients with external ventricular drainage due to intraventricular hemorrhage","authors":"Eylem Burcu Kahraman Özlü,&nbsp;Kaan Durmuş,&nbsp;Elçin Tuğce Mutlu,&nbsp;Ezgi Akar,&nbsp;Selin Tural,&nbsp;Arif Tarkan Çalışaneller","doi":"10.1016/j.neucie.2024.11.005","DOIUrl":"10.1016/j.neucie.2024.11.005","url":null,"abstract":"<div><h3>Background</h3><div>Intraventricular hemorrhages (IVH) are common pathologies in neurosurgery practice and are associated with the worst clinical outcome among all intracranial hemorrhages. Blood in the ventricles is thought to worsen the clinical condition by triggering inflammatory processes. In recent years, NLR value is a frequently used inflammatory parameter, and there are many publications reporting that a high NLR value is an important marker in predicting the severity of inflammation.</div><div>Our study aimed to evaluate the effect of NLR values at admission on the clinical outcome of patients undergoing EVD due to IVH in our clinic.</div></div><div><h3>Material and methods</h3><div>In our study, age and gender data, admission Glasgow Coma Scale (GCS), NLR value at the time of admission and clinical status at discharge of 36 patients, who underwent EVD following IVH in our hospital neurosurgery clinic between 2019 and 2024, were examined.</div></div><div><h3>Results</h3><div>Of the 36 cases in our study, 16 were female and 20 were male. For all cases, the mean age was 61.88, and the mean GCS values at admission were calculated as 8.5. In the laboratory of our hospital, the normal NLR range was determined as 0.78-3.53, and the mean NLR values at admission were evaluated as 16.57. When the clinical outcomes of the cases were examined, it was seen that 30 cases ended with exitus after intensive care follow-up, and 6 cases were discharged with good clinical outcomes (GCS:15). The mean NLR value was calculated as 18.00 for the patients who ended with exitus and 8.12 for the patients discharged with good clinical outcomes.</div></div><div><h3>Conclusion</h3><div>NLR, which has been used to determine the severity of inflammation in recent years, has been reported to be a marker that can predict clinical outcomes of many diseases. In our study, NLR was observed to be high at admission in all cases, but it was significantly higher in the cases ending with exitus than in the cases not ending with exitus. As a result, it is thought that NLR value is a parameter that can be used to predict the clinical course in IVH patients undergoing EVD.</div></div>","PeriodicalId":74273,"journal":{"name":"Neurocirugia (English Edition)","volume":"36 2","pages":"Pages 98-103"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}