Allergy proceedings : the official journal of regional and state allergy societies最新文献_第10页

Cross-reactivity of food allergens in latex allergy. 乳胶过敏中食物过敏原的交叉反应性。

Allergy proceedings : the official journal of regional and state allergy societies Pub Date : 1994-07-01 DOI: 10.2500/108854194778702711

V P Kurup, T Kelly, N Elms, K Kelly, J Fink

引用次数: 43

Introduction: mediator assays and inflammatory events in asthma and allergic disease (Immunology Research Institute of New England Symposium). 简介:哮喘和变应性疾病中的介质测定和炎症事件(新英格兰免疫学研究所研讨会)。

Allergy proceedings : the official journal of regional and state allergy societies Pub Date : 1994-05-01 DOI: 10.2500/108854194778702928

L M DuBuske

引用次数: 0

Adenosine and other mast cell preformed mediators. 腺苷和其他肥大细胞预形成介质。

Allergy proceedings : the official journal of regional and state allergy societies Pub Date : 1994-05-01 DOI: 10.2500/108854194778702883

D L Marquardt

引用次数: 2

Immunosuppressive agents in chronic severe asthma. 慢性重症哮喘的免疫抑制剂。

Allergy proceedings : the official journal of regional and state allergy societies Pub Date : 1994-05-01 DOI: 10.2500/108854194778702838

A B Kay

{"title":"Immunosuppressive agents in chronic severe asthma.","authors":"A B Kay","doi":"10.2500/108854194778702838","DOIUrl":"https://doi.org/10.2500/108854194778702838","url":null,"abstract":"Previous immunosuppressive agents utilized as therapies for immune system mediated diseases such as chronic allergic asthma, and rheumatoid arthritis include purine antagonists, methotrexate, and gold salts. These treatment modalities have been shown to elicit either limited treatment efficacy or to produce undesirable side effects in many individuals. Cyclosporin A is a potent immunosuppressive agent which appears to arrest division of T lymphocytes and inhibit mediator release from mast cells. However, like other immunosuppressive agents, cyclosporin A may also produce many potentially serious side effects; among these is the possibility of irreversible renal damage. Nephrotoxicity can be attenuated, because renal pathological changes seem to be high cumulative dose-related. If whole blood levels of cyclosporin A are maintained between 200 and 500 ng/mL, serious renal toxicity is unusual. Investigation of cyclosporin A in individuals who have severe long-term corticosteroid-dependent chronic asthma has demonstrated the efficacy of this agent, resulting in clinically significant improvement in pulmonary function. Therefore, it can be hypothesized that T lymphocytes may act as effector cells in cell-mediated hypersensitivity reactions in atopic allergic inflammation.","PeriodicalId":7423,"journal":{"name":"Allergy proceedings : the official journal of regional and state allergy societies","volume":"15 3","pages":"147-50"},"PeriodicalIF":0.0,"publicationDate":"1994-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2500/108854194778702838","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18529904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Mediator assays in aspirin-induced asthma. 阿司匹林诱发哮喘的中介分析。

Allergy proceedings : the official journal of regional and state allergy societies Pub Date : 1994-05-01 DOI: 10.2500/108854194778702955

A Szczeklik

引用次数: 3

Tryptase: a clinical indicator of mast cell-dependent events. 胰蛋白酶:肥大细胞依赖事件的临床指标。

Allergy proceedings : the official journal of regional and state allergy societies Pub Date : 1994-05-01 DOI: 10.2500/108854194778702946

L B Schwartz

引用次数: 51

Leukotrienes, fish-oil, and asthma. 白三烯，鱼油和哮喘。

Allergy proceedings : the official journal of regional and state allergy societies Pub Date : 1994-05-01 DOI: 10.2500/108854194778702874

J P Arm, F C Thien, T H Lee

引用次数: 11

Eosinophil activity in bronchial asthma. 支气管哮喘嗜酸性粒细胞活性。

Allergy proceedings : the official journal of regional and state allergy societies Pub Date : 1994-05-01 DOI: 10.2500/108854194778702937

P Venge

{"title":"Eosinophil activity in bronchial asthma.","authors":"P Venge","doi":"10.2500/108854194778702937","DOIUrl":"https://doi.org/10.2500/108854194778702937","url":null,"abstract":"Eosinophil cationic proteins (ECP), eosinophil protein X (EPX), eosinophil peroxidase (EPO), eosinophil-derived neurotoxin (EDN), and the major basic protein (MBP) have been identified as potent cytotoxic secretory proteins in degranulated eosinophils. Studies of these proteins have clearly indicated a role for eosinophil-derived proteins in inflammatory diseases, including asthmatic inflammation. It has been shown that higher levels of ECP in asthmatics were concomitant with severity of the disease and related to efficacy of treatment of asthma. Proper handling of blood serum for measurement of eosinophil and neutrophil markers including myeloperoxidase (MPO) is essential. Moreover, the time factor in ECP measurement is an important variable because ECP levels differ in chronic stable asthma, during acute exacerbations of asthma, and after allergen challenge. Simultaneous measurements of ECP and MPO may prove to be useful in determining various causes of asthma exacerbations, helping to discriminate between allergic etiologies wherein ECP levels may increase versus infectious etiologies wherein MPO levels may increase. Monitoring the efficacy of anti-inflammatory therapies such as corticosteroids may be enhanced by serial determinations of ECP levels in the blood.","PeriodicalId":7423,"journal":{"name":"Allergy proceedings : the official journal of regional and state allergy societies","volume":"15 3","pages":"139-41"},"PeriodicalIF":0.0,"publicationDate":"1994-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2500/108854194778702937","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18922778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 32

Importance of allergic etiology in nasal polyposis. 鼻息肉病过敏性病因的重要性。

Allergy proceedings : the official journal of regional and state allergy societies Pub Date : 1994-05-01 DOI: 10.2500/108854194778702892

E A Pastorello, C Incorvaia, G G Riario-Sforza, L Codecasa, V Menghisi, C Bianchi

{"title":"Importance of allergic etiology in nasal polyposis.","authors":"E A Pastorello, C Incorvaia, G G Riario-Sforza, L Codecasa, V Menghisi, C Bianchi","doi":"10.2500/108854194778702892","DOIUrl":"https://doi.org/10.2500/108854194778702892","url":null,"abstract":"Sensitization to environmental allergens in nasal polyposis was evaluated in an in vitro study conducted on 90 patients undergoing polypectomy by measuring total and specific IgE for a panel of common allergens and levels of IgG, IgA and albumin in serum, and nasal secretions (NSe). Fifty healthy individuals were chosen as a control group. Total IgE concentrations were higher in patients with nasal polyps than in controls. RAST was positive in serum in 34 (38%), in NSe in 29 (32%), and exclusively in NSe in 10 patients (11%). Allergens most frequently involved were mites and cat dander. No differences were found between the study and control groups for serum and NSe IgA, albumin, and serum IgG, whereas IgG in NSe were significantly higher in patients with nasal polyps. Subjects with positive RAST only in NSe had significantly lower secretory IgA than did controls. Our data indicate that in nasal polyposis: 1) sensitization to aeroallergens is relatively common; 2) a local production of specific IgE may occur, especially for perennial allergens; 3) prolonged exposure to these allergens gives rise to chronic nasal inflammation, with altered local production of immunoglobulins.","PeriodicalId":7423,"journal":{"name":"Allergy proceedings : the official journal of regional and state allergy societies","volume":"15 3","pages":"151-5"},"PeriodicalIF":0.0,"publicationDate":"1994-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2500/108854194778702892","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18922780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Occupational allergies in Finland in 1981-91. 1981-91年芬兰的职业性过敏。

Allergy proceedings : the official journal of regional and state allergy societies Pub Date : 1994-05-01 DOI: 10.2500/108854194778702919

K. Reijula, R. Patterson

{"title":"Occupational allergies in Finland in 1981-91.","authors":"K. Reijula, R. Patterson","doi":"10.2500/108854194778702919","DOIUrl":"https://doi.org/10.2500/108854194778702919","url":null,"abstract":"In 1981-91 in Finland, the number of cases with occupational asthma increased from 156 to 352 (125%), and with occupational rhinitis from 61 to 318 (421%), while the number of all cases of occupational diseases increased from 5060 to 8828. A total of 755 new patients with occupational allergic respiratory diseases and 558 with occupational allergic skin diseases were reported in 1991. This means that occupational allergies represent 15% of all cases of occupational diseases in Finland. The mean annual incidence of occupational respiratory diseases was 31 per 100,000 workers, 374 per 100,000 bakery workers, and 241 per 100,000 farmers. These data emphasize the important role of clinical allergy in the diagnosis of occupational disease during the time when some previously common occupational diseases such as toxic reactions to mercury and lead have become uncommon. Improved diagnosis of occupational allergic diseases would result in an improved control of the environment and reduction of diseases. Of particular interest is the establishment of the importance of occupational rhinitis, an issue that has been underemphasized as an occupational health problem in many countries.","PeriodicalId":7423,"journal":{"name":"Allergy proceedings : the official journal of regional and state allergy societies","volume":"41 1","pages":"163-8"},"PeriodicalIF":0.0,"publicationDate":"1994-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73061456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 33