Missouri medicine最新文献

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Missouri Medicine Announces New Board Member. 密苏里医药宣布新的董事会成员。
Missouri medicine Pub Date : 2026-03-01
Shourya Tadisina
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引用次数: 0
Electric Scooters: A Modern Method of Trauma. 电动滑板车:一种现代创伤治疗方法。
Missouri medicine Pub Date : 2026-03-01
Ryan Hoffman, James O'Brien, Matthew Cook
{"title":"Electric Scooters: A Modern Method of Trauma.","authors":"Ryan Hoffman, James O'Brien, Matthew Cook","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Electric scooters (e-scooters) have become a popular means of short-distance transportation for major metropolitan areas in several countries over the past decade. Their eco-friendliness, affordability, and ease of operation are selling points to people of all ages, particularly youth and young adults. Societal normalization has unfortunately overshadowed the risks entailed with their operation including severe injury and death. Alcohol, lack of protective equipment, and inadequate infrastructure appear to be common preventable risk factors. Emergency clinicians and trauma teams experience the aftermath of e-scooter injuries, which promise a rising trajectory. Common injury patterns have been identified by researchers around the world, most notably orthopedic, head, and maxillofacial in nature. Becoming familiar with these injury patterns and risk factors contributing to e-scooter accidents can be advantageous to the emergency physician's preparedness and public officials' approach to injury prevention.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 2","pages":"156-161"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13160477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147935984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ulnar Collateral Ligament Injuries in Youth Throwing Athletes. 青少年投掷运动员尺侧韧带损伤。
Missouri medicine Pub Date : 2026-03-01
Matthew J Steffes
{"title":"Ulnar Collateral Ligament Injuries in Youth Throwing Athletes.","authors":"Matthew J Steffes","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The medial ulnar collateral ligament (UCL) of the elbow is a vital structure for the overhead throwing motion. Injuries to this ligament are becoming increasingly common and specifically in youth baseball players. Significant work has been done to provide pitch count guidelines to monitor workload and prevent UCL injuries. Yet despite these efforts, injuries to the ulnar collateral ligament continue to occur at an alarming rate, leading to lost playing time and impacting player development. Complete tears of the UCL have traditionally been addressed surgically by reconstructing the ligament with a tendon graft, known as Tommy John Surgery. Newer techniques have allowed for repair of the native UCL tissue in many cases, drastically changing the treatment paradigm and subsequent rehabilitation.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 2","pages":"162-165"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13160465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrase Inhibitors: Redefining HIV-1 Treatment and Future Challenges. 整合酶抑制剂:重新定义HIV-1治疗和未来的挑战。
Missouri medicine Pub Date : 2026-03-01
Krishan K Pandey
{"title":"Integrase Inhibitors: Redefining HIV-1 Treatment and Future Challenges.","authors":"Krishan K Pandey","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The discovery and development of HIV-1 integrase strand transfer inhibitors (INSTIs) represent one of the remarkable success stories in antiviral drug discovery, transforming fundamental insights of retroviral enzymology into highly effective first-line therapies for HIV-1/AIDS patients. Currently there are five INSTIs approved for clinical use. Among these, second generation drugs Dolutegravir, Bictegravir and Cabotegravir offer excellent virologic suppression, favorable tolerability and a high genetic barrier to resistance. The long-acting formulation of the most recent INSTI Cabotegravir has also been approved for pre-exposure prophylaxis in high-risk populations. Apart from inhibiting the active site of integrase, a new class of allosteric integrase inhibitors (ALLINIs), which target integrase multimerization affecting multiple steps in viral life cycle, are in the advanced phases of clinical trials. The mechanisms of HIV-1 integration, development of integrase inhibitors, structural biology breakthroughs that guided inhibitor optimization and clinical use of INSTIs, their successes and challenges for HIV/1AIDS management are reviewed here.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 2","pages":"142-148"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13160474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shaping the Future: Why Physician Advocacy Matters for Patients, Physicians, and the Health System. 塑造未来:为什么医生倡导对患者、医生和卫生系统都很重要。
Missouri medicine Pub Date : 2026-01-01
David O Barbe
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引用次数: 0
Effective, Advocacy Communications with Legislators. 与立法委员进行有效的宣传沟通。
Missouri medicine Pub Date : 2026-01-01
{"title":"Effective, Advocacy Communications with Legislators.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 1","pages":"25"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12931599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147313316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2026 Physician Advocacy Day. 2026年医师倡导日。
Missouri medicine Pub Date : 2026-01-01
{"title":"2026 Physician Advocacy Day.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 1","pages":"24"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12931595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147313363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Food Dating: What Does it Really Mean? 食物约会:这到底意味着什么?
Missouri medicine Pub Date : 2026-01-01
Lauren Landfried, Jess Watson, Maggie McCoy, Anna Chott
{"title":"Food Dating: What Does it Really Mean?","authors":"Lauren Landfried, Jess Watson, Maggie McCoy, Anna Chott","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 1","pages":"18-20"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12931600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147312620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Partner in Healing: Our Lives Together in Medicine. 治疗的伙伴:我们在医学上的共同生活。
Missouri medicine Pub Date : 2026-01-01
Kathy Perryman
{"title":"Partner in Healing: Our Lives Together in Medicine.","authors":"Kathy Perryman","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 1","pages":"28-31"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12931571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147313131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
They Stole Your Umbrella: Why Healthcare Professionals Should Support Stronger Fraud Controls. 他们偷走了你的雨伞:为什么医疗保健专业人员应该支持更强有力的欺诈控制。
Missouri medicine Pub Date : 2026-01-01
Malcolm K Sparrow
{"title":"They Stole Your Umbrella: Why Healthcare Professionals Should Support Stronger Fraud Controls.","authors":"Malcolm K Sparrow","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 1","pages":"4-11"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12931588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147313111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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