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Sweetness at a Cost: The Story and Science of High-Fructose Corn Syrup. 甜是有代价的：高果糖玉米糖浆的故事和科学。
Missouri medicine Pub Date : 2026-05-01
Shourya Tadisina, Sreenija Dukkipati, Zar Tun, Adetoye Adebayo, Darla L McCarthy, Ray Segebrecht
{"title":"Sweetness at a Cost: The Story and Science of High-Fructose Corn Syrup.","authors":"Shourya Tadisina, Sreenija Dukkipati, Zar Tun, Adetoye Adebayo, Darla L McCarthy, Ray Segebrecht","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 3","pages":"200-206"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13252890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148229552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Financial Statements: Missouri State Medical Association. 财务报表：密苏里州医学协会。
Missouri medicine Pub Date : 2026-05-01
{"title":"Financial Statements: Missouri State Medical Association.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 3","pages":"279"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13252872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148229659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Cardiac Rhythm Monitoring After Ischemic Stroke: Detecting Atrial Fibrillation in the Era of Atrial Cardiopathy. 缺血性卒中后长期心律监测：心房心脏病时代的房颤检测。
Missouri medicine Pub Date : 2026-05-01
Kimberley Pfeiffer, Alibay Jafarli, Francisco E Gomez, Brandi R French, Adnan I Qureshi, Camilo R Gomez
{"title":"Long-Term Cardiac Rhythm Monitoring After Ischemic Stroke: Detecting Atrial Fibrillation in the Era of Atrial Cardiopathy.","authors":"Kimberley Pfeiffer, Alibay Jafarli, Francisco E Gomez, Brandi R French, Adnan I Qureshi, Camilo R Gomez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Long-term cardiac rhythm monitoring has become a central component of the diagnostic evaluation of patients with ischemic stroke in whom atrial fibrillation (AF) is suspected but not initially detected. Implantable loop recorders (ILRs) substantially increase AF detection compared with conventional short-term monitoring, particularly when surveillance is extended over months to years. However, increased detection has not consistently translated into fewer strokes, underscoring important limitations in current paradigms. Growing evidence supports atrial cardiopathy as the underlying substrate predisposing to thromboembolism, with AF representing a variable electrical manifestation rather than the primary disease itself. Electrocardiographic and echocardiographic markers of atrial cardiopathy, including abnormal P-wave indices, left atrial enlargement, and impaired atrial function, help identify patients most likely to benefit from prolonged monitoring. This review examines the role of ILRs in post-stroke patients through the lens of atrial cardiopathy, emphasizing biologic plausibility, patient selection, and disciplined interpretation of monitoring results to optimize clinical relevance and avoid uncritical escalation of therapy.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 3","pages":"248-252"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13252881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148228957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toxicology Testing: Interpreting What That Number Means. 毒理学测试：解读这个数字的含义。
Missouri medicine Pub Date : 2026-05-01
Nancy Mikati, Eniola Gros, Hannah Spungen, Michael D Levine, Evan S Schwarz
{"title":"Toxicology Testing: Interpreting What That Number Means.","authors":"Nancy Mikati, Eniola Gros, Hannah Spungen, Michael D Levine, Evan S Schwarz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 3","pages":"207-212"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13252880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148229639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risks and Benefits of Patients Using AI Chatbot Companions. 患者使用AI聊天机器人伴侣的风险和收益。
Missouri medicine Pub Date : 2026-03-01
Daniel B Shank
{"title":"Risks and Benefits of Patients Using AI Chatbot Companions.","authors":"Daniel B Shank","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 2","pages":"99-103"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13160459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammation as an Etiologic Agent of Gastric Cancer. 炎症是胃癌的病因之一。
Missouri medicine Pub Date : 2026-03-01
Javier A Carrero, Melody Zhang, Richard J DiPaolo
{"title":"Inflammation as an Etiologic Agent of Gastric Cancer.","authors":"Javier A Carrero, Melody Zhang, Richard J DiPaolo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic inflammation in the stomach significantly increases the risk of gastric cancer-a deadly disease with a poor prognosis, largely because it is often diagnosed too late. A better understanding of the pathophysiology and molecular mechanisms underlying this increased risk is essential to identify novel diagnostic and therapeutic targets for inflammation-induced carcinogenesis. Gastric epithelial atrophy, a precursor to cancer, can be induced by chemical, autoimmune, and infectious stimuli, primarily infection with <i>Helicobacter pylori</i>. We and others have shown that atrophy can also be induced by the secreted immune products (cytokines) of a type I/Th1 or Th17 immune response. The atrophic phase of gastritis is superseded by a metaplastic, or cellular redifferentiation phase driven by type II (Th2) cytokines. The outcome of this inflammatory sequela is dysplasia of the gastric epithelium; the substrate for multiple types of gastric cancers. Here we summarize our recent findings on Th1/Th17 and Th2 immune responses and their roles in driving gastric atrophy, metaplasia, and carcinogenesis. Importantly, these cytokines and their receptors represent promising therapeutic targets for the prevention and treatment of gastric cancer.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 2","pages":"130-135"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13160469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A New Paradigm to Put US Healthcare Back on Track. 让美国医疗保健重回正轨的新范式
Missouri medicine Pub Date : 2026-03-01
John C Hagan
{"title":"A New Paradigm to Put US Healthcare Back on Track.","authors":"John C Hagan","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 2","pages":"84-86"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13160475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Best Ever. 最好的。
Missouri medicine Pub Date : 2026-03-01
Donald G Sessions
{"title":"Best Ever.","authors":"Donald G Sessions","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 2","pages":"115"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13160467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What Is Your Legacy? 你的遗产是什么？
Missouri medicine Pub Date : 2026-03-01
Brian Biggers
{"title":"What Is Your Legacy?","authors":"Brian Biggers","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 2","pages":"110-111"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13160463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence in Healthcare: Transforming the Future. 医疗保健中的人工智能：改变未来。
Missouri medicine Pub Date : 2026-03-01
Abdelazeez Ihmeidan, Chi-Ren Shyu, Mai-Lan Ho
{"title":"Artificial Intelligence in Healthcare: Transforming the Future.","authors":"Abdelazeez Ihmeidan, Chi-Ren Shyu, Mai-Lan Ho","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"123 2","pages":"87-92"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13160461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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