{"title":"Looking Forward to AI and Medicine: Where Are We, and Where Are We Going?","authors":"Adam Wilcox, Malachi Griffith, Obi Griffith","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Artificial intelligence (AI) has emerged as a significant area of interest in medicine, with the potential to influence various aspects of health care. However, the real benefits of applications of AI to medicine often become obscured by the considerable attention, and hype, around its capabilities. To better understand AI's role in medicine, it is important to contextualize its development and review the stages of AI evolution that have contributed to its present state.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 1","pages":"34-38"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Private Equity and the Ravaging of United States Health Care.","authors":"James R Webster","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 1","pages":"7-10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Esra Pehlivan, John Zempel, Janette Coble, Sara Graves, Sean McEvoy, Matt Smyth, Kwee Liu Lin Thio, Christina Gurnett, Jarod Roland, Réjean M Guerriero, Stuart R Tomko
{"title":"Advanced Technology Clinic Provides Personalized Approach to Pediatric Epilepsy Surgery: Early Data and Future Directions.","authors":"Esra Pehlivan, John Zempel, Janette Coble, Sara Graves, Sean McEvoy, Matt Smyth, Kwee Liu Lin Thio, Christina Gurnett, Jarod Roland, Réjean M Guerriero, Stuart R Tomko","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Postoperative improvement in seizures may impact quality of life. We examined the relationship between reduced seizure burden and quality of life in a surgical epilepsy clinic.</p><p><strong>Methods: </strong>We reviewed data from all children who received epilepsy surgery at our center. Surgeries were classified as palliative or definitive based on the seizure outcome goals. We collected demographics, surgical data, Engel classification, and quality of life outcomes.</p><p><strong>Results: </strong>Between 2016 and 2024, 282 patients underwent 338 surgeries. In the definitive surgery group, 66 patients (58%) attained an Engel 1 outcome at six months and 46 patients (58%) at 24 months. In the palliative surgery group, six patients (7%) attained an Engel 1 outcome at six months. At 12 months, 75% of patients who attained Engel 1 reported lower depression scores.</p><p><strong>Conclusion: </strong>Improvement in seizure burden and quality of life outcomes following epilepsy surgery may be related. Further outcomes research is required.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 1","pages":"39-45"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Som Singh, Eric Errampalli, Nathan Errampalli, Mohammed Shah Miran
{"title":"Enhancing Patient Education on Cardiovascular Rehabilitation with Large Language Models.","authors":"Som Singh, Eric Errampalli, Nathan Errampalli, Mohammed Shah Miran","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>There are barriers that exist for individuals to adhere to cardiovascular rehabilitation programs. A key driver to patient adherence is appropriately educating patients. A growing education tool is using large language models to answer patient questions.</p><p><strong>Methods: </strong>The primary objective of this study was to evaluate the readability quality of educational responses provided by large language models for questions regarding cardiac rehabilitation using Gunning Fog, Flesh Kincaid, and Flesch Reading Ease scores.</p><p><strong>Results: </strong>The findings of this study demonstrate that the mean Gunning Fog, Flesch Kincaid, and Flesch Reading Ease scores do not meet US grade reading level recommendations across three models: ChatGPT 3.5, Copilot, and Gemini. The Gemini and Copilot models demonstrated greater ease of readability compared to ChatGPT 3.5.</p><p><strong>Conclusions: </strong>Large language models could serve as educational tools on cardiovascular rehabilitation, but there remains a need to improve the text readability for these to effectively educate patients.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 1","pages":"67-71"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew Hunter, Ashley E Douglas, Neann Wedgeworth, Julie M Kapp
{"title":"Overdose Data to Action in States (OD2A-S): Missouri's Response to the Opioid Epidemic.","authors":"Andrew Hunter, Ashley E Douglas, Neann Wedgeworth, Julie M Kapp","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 1","pages":"19-22"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Pathophysiology of Traumatic Brain Injuries and the Rationale Behind Creatine Supplementation as a Potential Therapy: A Review.","authors":"Faith I Vietor, Kayln Sticher, Komal H Ashraf","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Traumatic brain injuries (TBI) are detrimental to the brain in a variety of ways. Mild traumatic brain injuries (mTBI) are concussions; these are common events that disrupt typical brain functioning and send millions of patients to seek acute care each year globally. Despite the frequency of mTBIs, clinicians have few tools, pharmacologic and nonpharmacologic, to promote recovery and alleviate symptoms. After a TBI, complex biomolecular signaling, diffuse axonal stretching, and glutamate excitotoxicity occur, along with other pathological sequelae. Creatine has been shown to improve cognitive functioning in healthy adults. Burgeoning research is providing evidence that creatine may enhance recovery from TBI, as it directly targets derangements from such trauma.</p>","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"122 1","pages":"60-66"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Captain John C. Hagan III, USAF Medical Corp 1970-1972.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"121 6","pages":"451"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142857134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ulysses Fernandez-Miro, Pamala R Huges, Luke F Jett, Craig Krausz, Richard K Newman, Brandon M Parham, Julie K Gammack
{"title":"Military Medicine and Medical Education in Missouri.","authors":"Ulysses Fernandez-Miro, Pamala R Huges, Luke F Jett, Craig Krausz, Richard K Newman, Brandon M Parham, Julie K Gammack","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74203,"journal":{"name":"Missouri medicine","volume":"121 6","pages":"445-450"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11651252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142857164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}