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Decomposition of changes in malaria prevalence amongst under-five children in Nigeria. 尼日利亚五岁以下儿童疟疾流行率变化的分解。
MalariaWorld journal Pub Date : 2018-04-01 eCollection Date: 2018-01-01
Deborah O Owoeye, Joshua O Akinyemi, Oyindamola B Yusuf
{"title":"Decomposition of changes in malaria prevalence amongst under-five children in Nigeria.","authors":"Deborah O Owoeye,&nbsp;Joshua O Akinyemi,&nbsp;Oyindamola B Yusuf","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Malaria remains a major public health problem in Nigeria. Changes in malaria prevalence can be attributed to three major control interventions: insecticide treated nets (ITNs), indoor residual spraying (IRS) and intermittent preventive treatment in pregnancy (IPTp). Use of ITNs has proven to be a practical, highly effective, and cost-effective intervention against malaria. Although, several studies have assessed the utilisation of ITNs, its impact on the prevalence of malaria over time is yet to be documented in Nigeria. Therefore, this study was conducted to decompose changes in malaria prevalence amongst under-five children between 2003 and 2013.</p><p><strong>Materials and methods: </strong>A retrospective analysis of the 2003 and 2013 Nigeria Demographic Health Survey (NDHS) dataset was conducted. Occurrence of fever was used as a proxy for malaria. Percentage change in both outcome and explanatory variables between 2003 and 2013 was estimated. A multivariate decomposition technique was used to partition changes in malaria prevalence into two components: contribution of changes in determinants and changes in the effect of determinants.</p><p><strong>Results: </strong>A total of 5204 and 28634 records of children under-five were available in 2003 and 2013 respectively. Malaria prevalence declined from 31.8% to 13.1% between 2003 and 2013 (p<0.001). Changes in determinants contributed 4.7% and changes in the effect of determinants contributed 95.3% to the change in malaria prevalence.</p><p><strong>Conclusions: </strong>There was a decline in the prevalence of malaria amongst children under five in Nigeria in the last ten years. Ownership of ITNs and their utilisation were the most contributing factors to the decline in malaria prevalence. Continued efforts should be made in promoting ITNs and their consistent and appropriate utilisation.</p>","PeriodicalId":74100,"journal":{"name":"MalariaWorld journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39423886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sustainable financing to fight HIV/AIDS, TB and malaria: lessons learned from the African Union's Abuja Declaration. 抗击艾滋病毒/艾滋病、结核病和疟疾的可持续融资:从非洲联盟《阿布贾宣言》中吸取的教训。
MalariaWorld journal Pub Date : 2018-03-01 eCollection Date: 2018-01-01
Mabvuto Kango
{"title":"Sustainable financing to fight HIV/AIDS, TB and malaria: lessons learned from the African Union's Abuja Declaration.","authors":"Mabvuto Kango","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Investment in malaria control has been proven to contribute to socio-economic development. Concomitant investment in HIV/AIDS and Tuberculosis further augments these socio-economic gains. Africa has used this evidence to guide policy-making, especially for investment in the control of malaria and other infectious diseases. Pursuant to the objective of developing Africa, the Heads of State and Government of the OAU met in 2001 to address the challenges of HIV/AIDS, Tuberculosis and Malaria, a scourge that was ravaging the continent. Noting that the health sector in Africa needed more financial investment, the African leaders adopted a declaration that pledged to allocate at least 15% of their national annual budgets to the health sector.</p><p><strong>Materials and methods: </strong>Data was collected through review of documents and observations.</p><p><strong>Results: </strong>The implementation of the Abuja declaration drew a number of mixed results, positive ones which could be scaled up and some challenges that could be used as lessons for improvement.</p><p><strong>Conclusions: </strong>Taking everything into account, the Abuja Call was a relatively unprecedented success for Africa. With continuous improvement, the initiative could even do better. The African Union should consider revising the Abuja Call, based on lessons learned and emerging issues.</p>","PeriodicalId":74100,"journal":{"name":"MalariaWorld journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39423885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
End malaria for good: a review of current strategies and future novelties for malaria elimination in Nigeria. 永久消除疟疾:审查尼日利亚消除疟疾的当前战略和未来新举措。
MalariaWorld journal Pub Date : 2018-03-01 eCollection Date: 2018-01-01
Omosivie Maduka
{"title":"End malaria for good: a review of current strategies and future novelties for malaria elimination in Nigeria.","authors":"Omosivie Maduka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Malaria is endemic in 91 countries and territories. Currently, over half of the world's population is at risk for malaria with malaria prevalence in sub-Saharan Africa remaining the highest in the world. Nigeria accounts for 56% of malaria cases in the West African sub-region. Malaria control is historically the oldest control programme in Nigeria, having been in existence since 1948. Malaria control in Nigeria is guided by National Malaria Strategic Plans. The goal of the NMSP (2014-2020) is 'to reduce malaria burden to pre-elimination levels and bring malaria-related mortality to zero' using strategies under seven strategic objectives. The theme for the 2017 World Malaria Day activities was 'End Malaria for Good'. This theme indicates a sustained push for national and international commitments toward goal zero. Although the prevalence of malaria has dropped significantly, from 42% in 2010 to 27.4% in 2015, a lot of effort needs to be made to actualise a malaria-free Nigeria. This review discusses the current strategies in place to control and eliminate malaria. It also describes some future novelties available to sub-Saharan Africa and Nigeria to 'End Malaria for Good.'</p>","PeriodicalId":74100,"journal":{"name":"MalariaWorld journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39423884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of demand and supply predictors of uptake of intermittent preventive treatment for malaria in pregnancy in Malawi. 评估马拉维孕妇接受间歇性疟疾预防治疗的需求和供应预测因素。
MalariaWorld journal Pub Date : 2017-12-01 eCollection Date: 2017-01-01
Emmanuel N Odjidja, Predrag Duric
{"title":"Evaluation of demand and supply predictors of uptake of intermittent preventive treatment for malaria in pregnancy in Malawi.","authors":"Emmanuel N Odjidja,&nbsp;Predrag Duric","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The intermittent preventive treatment (IPTp) policy of Malawi (2002) stipulates that IPTp is administered during antenatal care as a direct observation therapy (DOT). The policy further recommends that IPT should be administered monthly after 16 weeks of pregnancy until delivery. This study assessed both the demand and supply factors contributing to higher dropout of IPT after the first dose. Optimal number of doses was pegged at a minimum of three in accordance with WHO recommendation.</p><p><strong>Materials and methods: </strong>Data were analysed from the Malawi multiple indicator cluster survey (2015) and the service provision assessment (2014) of 6637 women (aged 15- 49 yrs), 763 facilities and 2105 health workers. The sample was made up of pregnant women, health facilities and workers involved in routine antenatal services across all regions of Malawi. A composite indicator was constructed to report integration of IPTp with ANC services and administration of IPTp-SP as DOT. Multivariate and logistic regression were conducted to determine associations.</p><p><strong>Results: </strong>Regression analysis found that: 1. Age of women (women 35-49 yrs, AOR 1.98; 95% CI 1.42 - 2.13, number of children as well as the number of ANC visits were associated with optimal uptake of IPTp. 2. Administering IPT as DOT was higher in facilities in rural areas (AOR 1.86; 95% CI 1.54 - 1.92) than in urban areas. 3. Administration of IPTp as DOT was relatively lower in across all facilities with highest being facilities managed by CHAM (72.8%, AOR 1.40; 95% CI 1.22 - 1.54).</p><p><strong>Conclusion: </strong>Health system bottlenecks were found to present the main cause of low coverage with optimal doses of IPTp. Incorporating these results into strategic policy IPTp formulation could help improve coverage to desired levels. This study could serve as plausible evidence for government and donors when planning malaria in pregnancy interventions, especially in remote parts of Malawi.</p>","PeriodicalId":74100,"journal":{"name":"MalariaWorld journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39423883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malaria trends in Silt'i district from 2009-2015 and current childhood malaria in K'ibbet hospital, south-central Ethiopia. 2009-2015年淤泥区疟疾趋势和埃塞俄比亚中南部K'ibbet医院目前儿童疟疾情况。
MalariaWorld journal Pub Date : 2017-12-01 eCollection Date: 2017-01-01
Sani Dedgeba, Hassen Mamo
{"title":"Malaria trends in Silt'i district from 2009-2015 and current childhood malaria in K'ibbet hospital, south-central Ethiopia.","authors":"Sani Dedgeba,&nbsp;Hassen Mamo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Regular evaluation of the magnitude of malaria in children in a given locality is important to devise targeted control interventions. This study was conducted to assess current malaria infection among children (0-14 yrs) and trends in malaria between 2009 and 2015 in Silt'i district in south-central Ethiopia.</p><p><strong>Materials and methods: </strong>Febrile children (body temperature ≥37.5°C) visiting the K'ibbet hospital between September 2015 and January 2016 were enrolled. Finger-prick blood samples were collected, smears prepared, Giemsa-stained and examined. In addition, past (2009-2015) retrospective malaria data was reviewed. Descriptive statistics was used to analyse the data.</p><p><strong>Results: </strong>In the current cross-sectional survey, 43 (4.3%) children (n=1007) were diagnosed with malaria. Of these, 35 (81.4%) were <i>Plasmodium vivax</i> and only 8 (18.6%) <i>P. falciparum</i>. All cases were mono-infections. Concerning health data on record, overall 47,467 malaria-slide-confirmed cases were recorded (45.8% <i>P. vivax</i> and 54.2% <i>P. falciparum</i>), with a substantial decline in malaria between the baseline in 2009 (15,141 cases) and 2015 (821 cases).</p><p><strong>Conclusions: </strong>The findings demonstrated that malaria in children was continuously declining in the study area. However, control interventions must be maintained and scaled-up to sustainably protect children as well as the general population and eventually eliminate the disease from the locality and country as a whole.</p>","PeriodicalId":74100,"journal":{"name":"MalariaWorld journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39425440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of malaria and clinical profile of febrile HIV infected patients in three HIV clinics in Ivory Coast. 科特迪瓦三个艾滋病毒诊所的疟疾流行率和发热艾滋病毒感染患者的临床概况。
MalariaWorld journal Pub Date : 2017-11-01 eCollection Date: 2017-01-01
Yapo T Aba, Raoul Moh, Nogbou F Ello, Serge-Brice Assi, Ama M Ano, Brigitte Koffi, Mélaine C Mossou, Zelica Diallo, Emmanuel Bissagnene
{"title":"Prevalence of malaria and clinical profile of febrile HIV infected patients in three HIV clinics in Ivory Coast.","authors":"Yapo T Aba, Raoul Moh, Nogbou F Ello, Serge-Brice Assi, Ama M Ano, Brigitte Koffi, Mélaine C Mossou, Zelica Diallo, Emmanuel Bissagnene","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>To determine the prevalence and clinical profile of malaria among febrile HIV-infected patients followed up in three HIV clinics in Ivory Coast.</p><p><strong>Materials and methods: </strong>A cross-sectional multicentre study was conducted between 2009 and 2010 in the Pneumology Department of Cocody Teaching Hospital in Abidjan, Medical Esperance Centre and the Regional Hospital in San-Pedro. Patients of all ages presenting with fever (rectal or axillary temperature >37,5°C) or a medical history of fever within 72 hrs prior to consultation were included. Parasitological diagnostic methods used were microscopy by blood smear (BS) for search malaria parasite and parasite density. Haemoglobin levels were assessed to assess anaemia.</p><p><strong>Results: </strong>Over the study period, 530 people living with HIV consulted for fever. The 476 patients included were predominantly female (n=280, 59%), with a median age of 34 (range 3-74 yrs), a mean of 38 ± 8.3 (SD) yrs, infected with HIV-1 (n=409, 86%), on antiretroviral therapy (n=376, 79%), and cotrimoxazole prophylaxis (n=381, 80%). Only 73 (15%) patients were using LLINs. Malaria prevalence was 10% (n=47). <i>Plasmodium falciparum</i> was the only species identified with a mean density of 15 900 trophozoites/μl. Malaria was more common among patients with a CD4 count of <200/mm<sup>3</sup> (p<0.001) neither on cotrimoxazole prophylaxis (p<0.001) nor on antiretroviral therapy (ART) (p<0.001). Uncomplicated malaria accounted for 32 (68%) of the cases. The signs of severe malaria (n=15, 32%,) were dominated by severe anaemia (n= 12, 25.5%).</p><p><strong>Conclusion: </strong>Our study revealed that malaria prevalence appears to be low in HIV clinics for people living with HIV on HAART and cotrimoxazole prophylaxis. Uncomplicated malaria is predominant when consultation is early. Signs of severe malaria were dominated by severe anaemia.</p>","PeriodicalId":74100,"journal":{"name":"MalariaWorld journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39424414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long lasting impregnated mosquito net (LLIN) utilisation, incidence of fever and therapeutic itineraries: the case of Mifi health district in western Cameroon. 长效浸渍蚊帐(LLIN)的使用、发烧发生率和治疗行程:喀麦隆西部Mifi卫生区的案例。
MalariaWorld journal Pub Date : 2017-11-01 eCollection Date: 2017-01-01
Patrick P Nkamedjie, Ghyslaine B Dongho, Rodrigue B Mabvouna, Gianluca Russo, Martin S Sobze
{"title":"Long lasting impregnated mosquito net (LLIN) utilisation, incidence of fever and therapeutic itineraries: the case of Mifi health district in western Cameroon.","authors":"Patrick P Nkamedjie,&nbsp;Ghyslaine B Dongho,&nbsp;Rodrigue B Mabvouna,&nbsp;Gianluca Russo,&nbsp;Martin S Sobze","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Long Lasting Impregnated mosquito Net (LLIN) use is effective against malaria in endemic tropical areas. However, its utilisation remains limited. Among the most common clinical signs of malaria is fever and many studies have reported the existence of different local ways of handling fever; amongst which uncontrolled used of antimalarial drugs. We investigated LLINs use and its impact on fever outcomes and the various therapeutic measures used to deal with fever episodes.</p><p><strong>Materials and methods: </strong>Data was extracted from a cross sectional descriptive and analytic study performed between January and April 2014 in Mifi health district. Data was collected in households through a face to face interview with standard household questionnaires, treated and analysed using Epi Info statistical software version 3.5.3.</p><p><strong>Results: </strong>A total of 317 participants were interviewed with average age 33.2 years (SD = 10.8). Female respondents were predominant (85.2%; n=270). Most participants attended secondary education (53.6%; n= 170). Married marital status was most represented (58.1%; n= 185). 75.4% (n=239) of households owned at least 1 LLIN against an estimated average district coverage of 1 LLIN for 3.3 persons. Average bednet usage for households owning at least 1 LLIN was 57.9%. Utilisation of LLINs in households reduced fever episodes by 5.3%, (p=0.36). To handle fever episodes, road side medicines represented priority therapeutic itinerary for most of our respondents (95.0%; n=301).</p><p><strong>Conclusions: </strong>Although LLINs are effective in reducing fever episodes, their utilisation remains low. Self-medication to treat fever seems to be prominent. There is a need to optimise communication for behavioural change strategies to promote consistent LLIN use and anti-malarial therapy, assisted by qualified health personnel.</p>","PeriodicalId":74100,"journal":{"name":"MalariaWorld journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39424415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Locally transmitted malaria in Tawau, Sabah, Malaysia. 马来西亚沙巴州斗湖当地传播的疟疾。
MalariaWorld journal Pub Date : 2017-10-01 eCollection Date: 2017-01-01
Vivek J Jayaraj, Dhesi Baharaja, Navindran Gopalakrishnan, Yomain Kaco
{"title":"Locally transmitted malaria in Tawau, Sabah, Malaysia.","authors":"Vivek J Jayaraj,&nbsp;Dhesi Baharaja,&nbsp;Navindran Gopalakrishnan,&nbsp;Yomain Kaco","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Tawau was the epicentre of malaria infections in the 1970-1990's, when industrialisation swept across the state of Sabah, Malaysia. Since then, effective public health intervention, mainly the Malaria Elimination Programme, introduced in 1998, has seen the disease shrivel down into its final elimination phase. Here we retrospectively analyse the case of a 63 year old male with multiple comorbidities who had no exposure to localities with high risk of infection- thus raising the question regarding the means of transmission.</p><p><strong>Materials and methods: </strong>Multiple interviews and an entomological survey were conducted to elucidate the possible mechanism of infection in this patient.</p><p><strong>Results: </strong>Findings point to locally-transmitted malaria, likely introduced by a patient from an endemic region in Tawau. Transmission via this route is rare, and has never before been reported in our setting.</p><p><strong>Conclusions: </strong>This rare case highlights the need for constant vigilance in malaria control and elimination, especially when the target of country-wide elimination is close.</p>","PeriodicalId":74100,"journal":{"name":"MalariaWorld journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39424412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative assessment of malaria rapid diagnostic tests (RDT) in Ibadan, Nigeria. 尼日利亚伊巴丹疟疾快速诊断检测(RDT)比较评估。
MalariaWorld journal Pub Date : 2017-10-01 eCollection Date: 2017-01-01
Rose I Ilesanmi, Oluwasogo A Olalubi, Oluwasegun T Adetunde, Ayodele O Ilesanmi, Hyacinth Effedua, Abimbola O Amoo
{"title":"Comparative assessment of malaria rapid diagnostic tests (RDT) in Ibadan, Nigeria.","authors":"Rose I Ilesanmi, Oluwasogo A Olalubi, Oluwasegun T Adetunde, Ayodele O Ilesanmi, Hyacinth Effedua, Abimbola O Amoo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Deployment of sound diagnostic tests remains a crucial component of malaria management, prevention and control in Africa. We undertook a comparative assessment of sensitivity, specificity and efficiency of three popular brands of rapid diagnostic tests (RDT) available in Nigerian market alongside with traditional microscopy.</p><p><strong>Materials and methods: </strong>525 samples of patients that presented with acute uncomplicated malaria through clinical diagnosis were evaluated with the various tests. Total WBC count and haematocrit were also measured.</p><p><strong>Results: </strong>Of the 525 samples, 300 (57.1%) were found positive by Giemsa microscopy. SD Bioline had a positivity rate of 49.5% (260/525), while the positivity rate for Acon was significantly lower (38.1%; 200/525) and Paracheck (28.6%; 150/525). The sensitivity, specificity and efficiency of the three RDTs were: SD Bioline (86.3%, 99.6%, 92%); Paracheck (50%, 97.7%, 70.4%) and Acon (66.7%, 100%, 80.9%), respectively. Pre-teens aged 6-12 yrs had the highest mean malaria parasite densities with 6,631.26 at p< 0.01. The dominant malaria species was <i>Plasmodium falciparum</i> with 280 (93.3%) cases. Co-infections of <i>P. falciparum/vivax</i> (15; 5.0%) and <i>P. falciparum/malariae</i> (5; 1.7%) were detected and confirmed with microscopy. Haematocrit values correlated inversely with parasite density (r = -0.744; <i>p</i>< 0.01).</p><p><strong>Conclusions: </strong>Microscopy still remains the reference standard for malaria diagnosis in limited resource settings in endemic areas. In furtherance to this, there is need for consistent monitoring of RDT product quality as part of the distribution process to end-users across Nigeria.</p>","PeriodicalId":74100,"journal":{"name":"MalariaWorld journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39424413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malaria infection at parturition in Abeokuta, Nigeria: Current status and pregnancy outcome. 尼日利亚阿贝奥库塔市分娩时的疟疾感染:现状与妊娠结局
MalariaWorld journal Pub Date : 2017-08-01 eCollection Date: 2017-01-01
Ayodele S Babalola, Olufunmilayo A Idowu, Sammy O Sam-Wobo, And Eniola Fabusoro
{"title":"Malaria infection at parturition in Abeokuta, Nigeria: Current status and pregnancy outcome.","authors":"Ayodele S Babalola, Olufunmilayo A Idowu, Sammy O Sam-Wobo, And Eniola Fabusoro","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>There is dearth of information on perinatally acquired malaria, as well as its burden in Nigeria. We determined the prevalence of pregnancy-associated malaria and its burden among parturients in Abeokuta, Ogun State.</p><p><strong>Materials and methods: </strong>Blood films from 211 parturients were prepared, stained with 10% Giemsa and examined using microscopy. Relevant demographic information was recorded from study participants. Chi-square tests were used to analyse data using SPSS version 20.0.</p><p><strong>Results: </strong>Prevalence of maternal peripheral, placenta and cord blood parasitaemia were 40.8%, 19.0% and 5.7% respectively, and these were significantly correlated with age and gravidity. Prevalence of maternal anaemia was 45.0%, and was significantly associated with malaria infection. The occurrence of Low Birth Weight (LBW) was 10%. Maternal, placental and cord infections with malaria were associated with LBW, with the highest percentage of LBW occurring in babies with high placental malaria parasite density. Preterm delivery and stillbirth were significantly associated with placenta and cord malaria.</p><p><strong>Conclusions: </strong>Impact of malaria on the mother and the newborns, notably anaemia and LBW, solicits the need for promoting use of available malaria prevention during pregnancy. These include LLINs and IPTp.</p>","PeriodicalId":74100,"journal":{"name":"MalariaWorld journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8415052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39424408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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