疟疾先驱罗伯特-科赫

MalariaWorld journal Pub Date : 2022-02-01 eCollection Date: 2022-01-01
Jan Peter Verhave
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摘要

罗伯特-科赫(Robert Koch)在早期发现疟疾的生命周期、疾病的复杂性、免疫力的发展、奎宁预防和蚊子理论等方面的作用已被人们遗忘。作为一名成熟而著名的卫生学家,科赫曾游历过疟疾流行的旧大陆。1898 年,他在德属东非坦噶尼喀(今坦桑尼亚)进行了首次研究,此后又在意大利和东亚群岛进行了研究。由于德国的疟疾流行情况不够理想,他选择了伊斯特拉岛的布里奥尼(克罗埃西亚)来消灭疟疾。由于科赫的出版物几乎都是德文,他在疟疾方面的成就从未在热带医学的共同记忆中留下痕迹。大约在世纪之交,人们开始竞相阐明通过蚊子传播疟疾的途径,尽管他几乎没有获得任何优先权,但他的研究无疑决定了英国和意大利竞争者的发展速度。在他的努力和干预下,第二届诺贝尔医学奖只颁给了罗纳德-罗斯,乔瓦尼-巴蒂斯塔-格拉西(Giovanni Battista Grassi)则名落孙山。在现代疟疾研究开始之初的那场众所周知的争吵中,他的干预再次证明了个人性格是如何冲突或联合的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Robert Koch, malaria pioneer.

Robert Koch, malaria pioneer.

Robert Koch, malaria pioneer.

Robert Koch, malaria pioneer.

The role of Robert Koch in the early discoveries of the malaria lifecycle and the complex of diseases, the development of immunity, quinine prophylaxis and the mosquito theory has fallen into oblivion. As a mature and famous hygienist, Koch had travelled the Old World, where malaria was endemic. His first studies took place in Tanganyika, German East Africa (now Tanzania) in 1898 and thereafter in Italy and the East Asian archipelago. As malaria in Germany did not offer a sufficiently endemic situation, he chose the Istrian island of Brioni (Kroatia) to eliminate malaria. Because virtually all of Koch's publications are in German, his achievements on malaria never settled in the common memory of tropical medicine. Around the turn of the century the race to elucidate the transmission pathway through mosquitoes took place and though he hardly yielded any honour of priority, his research certainly determined the speed by which British and Italian contenders made their ways. His exertion and interference led to the awarding of the 2nd Nobel Prize in Medicine to Ronald Ross only, leaving Giovanni Battista Grassi to draw the blank. Proof of this intervention in the otherwise well-known quarrel at the start of modern malaria research shows once more how personal characters may clash or join forces.

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