Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)最新文献

{"title":"Effect of intra-abdominal hypertension on plasma exogenous creatinine clearance in conscious and anesthetized dogs.","authors":"Min Jang,&nbsp;Won-Gyun Son,&nbsp;Sang-Min Jo,&nbsp;Hyunseok Kim,&nbsp;Chi Won Shin,&nbsp;Inhyung Lee","doi":"10.1111/vec.12853","DOIUrl":"https://doi.org/10.1111/vec.12853","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effect of intra-abdominal pressure (IAP) on plasma exogenous creatinine clearance in both conscious and anesthetized dog models using a balloon technique to generate intra-abdominal hypertension.</p><p><strong>Design: </strong>Prospective, cross-over, experimental study.</p><p><strong>Setting: </strong>University-based small animal research facility.</p><p><strong>Animals: </strong>Six healthy male Beagle dogs.</p><p><strong>Interventions: </strong>A balloon device comprising a Foley urinary catheter and latex balloon was placed in the intra-abdominal cavity. Plasma exogenous creatinine clearance was compared after intravenous administration of exogenous creatinine solution at 80 mg/kg under 4 different treatment conditions as follows: control and IAP levels of 25 mm Hg in conscious dogs and control and IAP levels of 25 mm Hg in anesthetized dogs (CC, C25, AC, and A25, respectively). Samples were obtained before (T0) and 10, 20, 30, 60, 90, 120, 240, 360, 480, and 600 min after administration of creatinine in all treatment groups.</p><p><strong>Measurements and main results: </strong>There were no significant differences in plasma creatinine concentration for CC, AC, and C25 during the treatment period. However, in the A25 treatment condition, the plasma creatinine concentration increased significantly at 10, 20, 30, 60, 90, and 120 min after administration of creatinine (P < 0.05). Plasma creatinine clearances were 5.0 ± 0.5, 4.7 ± 1.2, 5.5 ± 0.9, and 2.5 ± 0.5 mL/kg/min for 600 min (CC, AC, C25, and A25, respectively). In the A25 treatment condition, the plasma exogenous creatinine clearance decreased significantly to 50%, 47%, and 55% of that under control conditions (CC, AC, and C25, respectively). After decompression of the abdomen, plasma creatinine concentrations declined rapidly and returned to basal concentrations.</p><p><strong>Conclusions: </strong>Intra-abdominal hypertension under general anesthesia could cause renal hypoperfusion. Timely decompression may improve the outcome of acutely increased IAP when surgery and/or general anesthesia is required in canine patients.</p>","PeriodicalId":74015,"journal":{"name":"Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)","volume":"29 4","pages":"366-372"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/vec.12853","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37348382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemangiosarcoma Likelihood Prediction (HeLP) Score: Methodological issues on prediction.","authors":"Siamak Sabour,&nbsp;Javad Roushani","doi":"10.1111/vec.12850","DOIUrl":"https://doi.org/10.1111/vec.12850","url":null,"abstract":"","PeriodicalId":74015,"journal":{"name":"Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)","volume":"29 4","pages":"451-452"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/vec.12850","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37341900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of hydromorphone and dexmedetomidine for emesis induction in cats.","authors":"Michael R Nystrom,&nbsp;Adesola Odunayo,&nbsp;Chika C Okafor","doi":"10.1111/vec.12866","DOIUrl":"https://doi.org/10.1111/vec.12866","url":null,"abstract":"<p><strong>Objective: </strong>To compare the efficacy of hydromorphone and dexmedetomidine at inducing emesis in cats.</p><p><strong>Design: </strong>Prospective, blinded, randomized crossover study.</p><p><strong>Setting: </strong>Veterinary university teaching hospital.</p><p><strong>Animals: </strong>12 healthy purpose-bred cats.</p><p><strong>Interventions: </strong>Cats were randomly assigned to receive hydromorphone (0.1 mg/kg, subcutaneously) or dexmedetomidine (7 μg/kg, IM). Following administration, the incidences of emesis, number of emetic events, signs of nausea (hypersalivation, lip licking), temperature, heart rate, respiratory rate, and sedation score were recorded for 6 hours.</p><p><strong>Measurements and main results: </strong>Emesis was successful in 9 of 12 (75%) cats when treated with hydromorphone and in 7 of 12 (58%) cats when treated with dexmedetomidine (P = 0.67). Dexmedetomidine was more likely to cause sedation than hydromorphone (P < 0.001). Heart rate in cats was significantly decreased at 1 and 2 hours post-hydromorphone (P = 0.003, 0.014, respectively) and at 1, 2, 3, 5, 6 hours post-dexmedetomidine (P = 0.001, 0.003, 0.038, 0.013, 0.001, respectively). Cats were more likely to develop an increase in body temperature with hydromorphone administration although this was not clinically significant.</p><p><strong>Conclusions: </strong>Results of the present study indicate that hydromorphone is an effective alternative to dexmedetomidine for the induction of emesis in cats. Hydromorphone appears to cause less sedation and less decrease in heart rate. Further investigation into the most adequate dose of hydromorphone for optimizing emesis is warranted.</p>","PeriodicalId":74015,"journal":{"name":"Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)","volume":"29 4","pages":"360-365"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/vec.12866","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37362524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pilot study evaluating the effects of prestorage leukoreduction on markers of inflammation in critically ill dogs receiving a blood transfusion.","authors":"Luis Bosch Lozano,&nbsp;Shauna L Blois,&nbsp;R Darren Wood,&nbsp;Anthony C G Abrams-Ogg,&nbsp;Alexa M Bersenas,&nbsp;Shane W Bateman,&nbsp;Danielle M Richardson","doi":"10.1111/vec.12857","DOIUrl":"https://doi.org/10.1111/vec.12857","url":null,"abstract":"<p><strong>Objectives: </strong>To compare markers of inflammation after transfusion of leukoreduced (LR) packed RBCs (pRBCs) versus non-LR pRBCs in dogs with critical illness requiring blood transfusion, and to report survival to discharge and rates of transfusion reactions in these dogs.</p><p><strong>Design: </strong>Prospective randomized blinded clinical study June 2014-September 2015.</p><p><strong>Setting: </strong>University veterinary teaching hospital.</p><p><strong>Animals: </strong>Twenty-three client-owned critically ill dogs, consecutively enrolled.</p><p><strong>Interventions: </strong>Dogs requiring a single pRBC transfusion were randomized into the LR or non-LR pRBC group. Exclusion criteria included: requirement for multiple blood products, history of previous blood transfusion, and administration of anti-inflammatory or immunosuppressive medication prior to enrollment.</p><p><strong>Measurements: </strong>Blood samples were obtained immediately prior to transfusion, then 2 and 24 hours following transfusion. Parameters measured at each time point included: PCV, WBC count, segmented and band neutrophil counts, fibrinogen, and plasma lactate and C-reactive protein concentrations. Acute patient physiologic and laboratory evaluation fast score was calculated on admission.</p><p><strong>Results: </strong>Eleven dogs were included in the LR group and 12 in the non-LR group; scores of illness severity were not significantly different between groups. Total WBC count was significantly higher in the non-LR versus LR group 24 hours following pRBC transfusion, but this difference was not evident 2 hours following transfusion. No other inflammatory parameters at any time point were significantly different between LR versus non-LR pRBC transfused dogs. Survival rates to discharge for LR and non-LR groups were 8/11 and 9/12, respectively. Acute transfusion reactions were identified in 1/11 and 2/12 dogs in the LR and non-LR group, respectively. All transfused blood was stored ≤12 days.</p><p><strong>Conclusions: </strong>Most markers of inflammation did not significantly increase following transfusion of LR versus non-LR pRBCs stored ≤12 days in ill dogs. Further prospective, randomized trials are needed in clinically ill dogs to determine the benefit of prestorage leukoreduction.</p>","PeriodicalId":74015,"journal":{"name":"Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)","volume":"29 4","pages":"385-390"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/vec.12857","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37345612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between computed tomographic thoracic injury scores and blood gas and acid-base balance in dogs with blunt thoracic trauma.","authors":"Robert M Kirberger,&nbsp;Andrew L Leisewitz,&nbsp;Yolandi Rautenbach,&nbsp;Chee Kin Lim,&nbsp;Nerissa Stander,&nbsp;Nicky Cassel,&nbsp;Luke Arnot,&nbsp;Marizelle deClercq,&nbsp;Richard Burchell","doi":"10.1111/vec.12863","DOIUrl":"https://doi.org/10.1111/vec.12863","url":null,"abstract":"<p><strong>Objective: </strong>To determine the association between thoracic injuries evaluated by computed tomography (CT) and arterial blood gas and acid-base status in dogs with blunt thoracic trauma caused by motor vehicle accidents.</p><p><strong>Design: </strong>Prospective observational clinical study.</p><p><strong>Setting: </strong>University teaching hospital.</p><p><strong>Animals: </strong>Thirty-one client owned traumatized dogs and 15 healthy dogs.</p><p><strong>Procedures: </strong>All trauma group dogs underwent a CT scan and simultaneous arterial blood gas analysis within 24 hours, but not before 4 hours, after the traumatic incident within a 45-month enrollment period.</p><p><strong>Measurements and main results: </strong>Thorax injuries were classified as pulmonary, pleural space, or rib cage and each of these components was scored for severity using a CT composite pulmonary, pleural, and rib score. The trauma group arterial blood gas and acid-base status were evaluated for statistical difference from the control group. The pulmonary-arterial oxygen pressure was significantly lower in the trauma group compared to the control group that was supported by significant differences in the calculated variables of arterial blood oxygenation as well. There was also a significant correlation between the composite lung score and pleural score and the variables of arterial oxygen status. The pulmonary-arterial carbon dioxide pressure was not significantly different to any of the thoracic injury variables indicating normal alveolar ventilation. Acid-base imbalances were generally mild, insignificant, and variable.</p><p><strong>Conclusions and clinical relevance: </strong>Blunt thoracic trauma causes significant pulmonary and pleural injury and the blood oxygen economy is significantly affected by this. The functional measures of arterial blood oxygenation were well correlated with thoracic CT pathology. Alveolar ventilation was mostly spared but a clinically significant ventilation perfusion mismatch was present.</p>","PeriodicalId":74015,"journal":{"name":"Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)","volume":"29 4","pages":"373-384"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/vec.12863","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37362327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Warning regarding 5-fluorouracil intoxication and calculation of dose exposure.","authors":"Eric N Glass,&nbsp;Marc Kent,&nbsp;Rachel B Song","doi":"10.1111/vec.12849","DOIUrl":"https://doi.org/10.1111/vec.12849","url":null,"abstract":"","PeriodicalId":74015,"journal":{"name":"Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)","volume":"29 4","pages":"450"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/vec.12849","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37086225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe acute cellulitis and sepsis caused by Aeromonas spp. in a dog on immunosuppressive therapy.","authors":"Kate Alice Worthing,&nbsp;Jacqueline M Norris,&nbsp;Katherine Anne Briscoe","doi":"10.1111/vec.12867","DOIUrl":"https://doi.org/10.1111/vec.12867","url":null,"abstract":"<p><strong>Objective: </strong>To describe the clinical presentation, diagnostic investigation, and medical management of a dog on immunosuppressive therapy that developed a severe soft tissue infection attributed to Aeromonas hydrophila/caviae.</p><p><strong>Case summary: </strong>A 5-year-old female neutered Border Collie dog was presented for investigation of a rapidly growing skin lesion. The dog had been diagnosed with immune-mediated thrombocytopenia and was receiving immunosuppressive therapy for 5 weeks. Physical examination at initial presentation revealed no abnormalities except a 6 cm raised, erythematous, firm, and painful swelling on the ventral abdomen. Within 12 hours of admission, the lesion had expanded to cover much of the ventrum and some areas had begun to slough. The patient had also become obtunded and exhibited pyrexia, tachypnea, tachycardia as well as extreme pain around the lesion. The dog's clinical signs and hematology results were consistent with sepsis. Histopathology showed severe acute suppurative cellulitis and panniculitis and a heavy growth of A. hydrophila/caviae was obtained on tissue culture. The infection was treated with trimethoprim sulphadiazine, based on culture and susceptibility results.</p><p><strong>Unique information provided: </strong>This is the first reported case of severe panniculitis and cellulitis caused by Aeromonas spp. in a dog. Aeromonas spp. should be considered a differential diagnosis for cases of severe soft tissue infection, especially in immune-compromised animals or those with a history of aquatic exposure.</p>","PeriodicalId":74015,"journal":{"name":"Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)","volume":"29 4","pages":"444-449"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/vec.12867","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37362528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective evaluation of the clinical presentation, magnetic resonance imaging findings, and outcome of dogs diagnosed with intracranial empyema (2008-2015): 9 cases.","authors":"Alexander K Forward,&nbsp;Ioannis N Plessas,&nbsp;Sérgio Guilherme,&nbsp;Steven De Decker","doi":"10.1111/vec.12859","DOIUrl":"https://doi.org/10.1111/vec.12859","url":null,"abstract":"<p><strong>Objective: </strong>To describe the clinical presentation, advanced imaging findings, and short- and long-term outcomes in dogs with intracranial empyema.</p><p><strong>Design: </strong>Retrospective case series.</p><p><strong>Animals: </strong>Client-owned dogs diagnosed with intracranial empyema.</p><p><strong>Methods: </strong>Medical records from 2 referral hospitals were searched for dogs diagnosed with intracranial empyema. To be included in this study, dogs had to fulfill 1 or more of the following 3 inclusion criteria: a magnetic resonance imaging (MRI) scan with space occupying accumulation of extra-axial material suggestive of empyema, a cerebrospinal fluid analysis suggestive of empyema, or direct visualization of purulent material during intracranial surgery.</p><p><strong>Results: </strong>Nine dogs with intracranial empyema were included, with a median age of 3.5 years (range: 4 mo-12.5 y). All presented as emergencies with 7 of the 9 dogs showing neurological abnormalities and 2 of the 9 with retrobulbar swelling and exophthalmos. Six had surgical intervention, 1 was medically managed, and the remaining 2 dogs were euthanized. Typical MRI findings included extra-axial, T1-weighted hypo- to isointense, T2-weighted hyperintense material compared to gray matter with varying degrees of contrast enhancement, with 6 of 8 showing evidence of contiguous infection from adjacent structures on MRI. For 7 dogs, ≥1 samples were sent for culture and sensitivity, with Enterococcus (surgical swab), Streptococcus pneumonia (from cerebral spinal fluid), and coagulase positive Staphylococcus (ear swab) being cultured. The median antimicrobial course length was 6 weeks (range: 2-28 wk). All dogs for which treatment was attempted survived to discharge, with a median hospitalization time of 7 days (range: 4-10 d). Four of the 7 are still alive at the time of writing (1 lost to follow-up; 2 euthanized for other reasons) with all 4 considered neurologically normal with a successful long-term outcome.</p><p><strong>Conclusion: </strong>Although intracranial empyema in dogs is a rare condition, excellent outcomes are possible in those cases treated appropriately.</p>","PeriodicalId":74015,"journal":{"name":"Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)","volume":"29 4","pages":"431-438"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/vec.12859","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37348645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective evaluation of the association between admission blood glucose and l-lactate concentrations in ponies and horses with gastrointestinal disease (2008-2016): 545 cases.","authors":"Bettina Dunkel,&nbsp;Charlotte Jane Mason,&nbsp;Yu-Mei Chang","doi":"10.1111/vec.12851","DOIUrl":"https://doi.org/10.1111/vec.12851","url":null,"abstract":"<p><strong>Objectives: </strong>A recent study described increased l-lactate concentrations in ponies with gastrointestinal disease compared to horses, but blood glucose (BG) concentrations were not considered. The study tested the hypothesis that BG and l-lactate concentrations are correlated in horses and ponies with gastrointestinal disease and that BG concentrations, not equid type (pony vs horse), are an independent predictor of L-lactate concentrations. It was further hypothesized that equid type was an independent predictor of BG concentrations.</p><p><strong>Design: </strong>Retrospective study 2008-2016.</p><p><strong>Setting: </strong>University teaching hospital.</p><p><strong>Animals: </strong>Admission data from 545 animals (384 horses and 161 ponies) with gastrointestinal disease.</p><p><strong>Interventions: </strong>None.</p><p><strong>Measurements and main results: </strong>Data collected included signalment, clinicopathological findings on admission, and nature and location of the gastrointestinal lesion (strangulating vs non-strangulating and large vs small intestinal lesion). The association between admission blood l-lactate concentrations, equid type (pony or horse) and BG concentrations was investigated in a multivariable model. Admission l-lactate and BG concentrations were strongly correlated (n = 522; r = 0.63; P < 0.001). Ponies had significantly higher l-lactate (2.7 mmol/L (0.5-18.0 mmol/L) vs 1.4 mmol/L (0.3-19 mmol/L); P < 0.001) and BG concentrations than horses (8.4 mmol/L (4.2-24.4 mmol/L); 151 mg/dL (76-439 mg/dL) vs 6.9 mmol/L (3.4-26.8 mmol/L); 124 mg/dL (61-482 mg/dL); P < 0.001). In the multivariable analysis, l-lactate concentrations were significantly and positively associated with admission BG concentrations in all animals and also with equid type. For each millimole per liter (18 mg/dL) increase in BG, l-lactate concentrations increased by 7.9% (5.9, 9.9); P < 0.001. In comparison to ponies, l-lactate concentrations were decreased by 27.7% (37.4, 16.5); P < 0.001 in horses. Admission BG concentrations were significantly and positively associated with l-lactate concentrations in all animals. For each millimole per liter increase in l-lactate concentration, BG concentration increased by 6.2% (4.7, 7.6; P < 0.001). Admission BG concentrations were not associated with equid type.</p><p><strong>Conclusion: </strong>Admission BG concentrations and equid type are independent predictors of blood l-lactate concentrations in equids with gastrointestinal disease, but their relationship requires further investigation.</p>","PeriodicalId":74015,"journal":{"name":"Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)","volume":"29 4","pages":"418-423"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/vec.12851","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37069680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Question relating to the methodology of a study evaluating thromboelastography and platelet aggregometry in healthy dogs.","authors":"","doi":"10.1111/vec.12808","DOIUrl":"https://doi.org/10.1111/vec.12808","url":null,"abstract":"","PeriodicalId":74015,"journal":{"name":"Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)","volume":"29 2","pages":"210"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/vec.12808","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36924500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}