Journal of trace elements and minerals最新文献

{"title":"Bioaccumulation of metals and metalloids in seafood: A comprehensive overview of mobilization, interactive effects in eutrophic environments, and implications for public health risks","authors":"Sukhendu Dey ,&nbsp;Prem Rajak ,&nbsp;Kamalesh Sen","doi":"10.1016/j.jtemin.2024.100141","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100141","url":null,"abstract":"<div><p>This article delves into the intricate dynamics of metals and metalloids (MEs and MLOIDs) bioaccumulation in seafood, with a focus on mobilization processes and interactive effects in eutrophic environments. It unveils critical insights into the mechanisms influencing contaminant concentration in marine organisms, and thoroughly examines the implications for public health risks. The study emphasizes the multifaceted challenges posed by MEs and MLOIDs bioaccumulation in seafood, highlighting the necessity of understanding these complexities to develop effective strategies for mitigating environmental impact and safeguarding public health. The overview comprehensively explores the bioaccumulation and biomagnification of MEs and MLOIDs within aquatic ecosystems, covering sources, entry mechanisms, speciation, and transformation. It investigates the gradual buildup of substances in marine species tissue, emphasizing the use of environmental biomonitoring for metal pollution and assessing risks associated with consuming contaminated seafood. Key considerations include dietary exposure, the effects of processing on toxic MEs and MLOIDs contents, and the bioavailability of these elements in seafood products. The study examines constructive biomarkers as crucial indicators of MEs and MLOIDs contamination, ranging from metallothioneins (MTs) to DNA damage biomarkers. It evaluates their role in environmental monitoring, risk assessment, and regulatory measures, emphasizing the integration of exposure and effect biomarkers for a comprehensive approach to ensuring the quality and safety of seafood products. The article advocates ongoing research for refining biomarkers, exploring isotopic ratios, and understanding the effects of processing methods. It underscores the importance of collaborative efforts among scientists, regulatory bodies, and the seafood industry to tailor measures to regional contexts. The study envisions a proactive and informed strategy to foster environmental conservation and public well-being in response to MEs and MLOIDs contamination in seafood.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"8 ","pages":"Article 100141"},"PeriodicalIF":0.0,"publicationDate":"2024-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000260/pdfft?md5=3acc4997474a75737c775e0432360459&pid=1-s2.0-S2773050624000260-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140880156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Lead and lead isotopes as tracers of soil contamination in southwestern Nigeria”. [Journal of Trace Elements and Minerals 5C (2023) 100086]","authors":"Tesleem O. Kolawole ,&nbsp;Jerry O. Olajide-Kayode ,&nbsp;Olubukola O. Afolabi ,&nbsp;Luqmon A. Azeez ,&nbsp;Adebanjo J. Anifowose ,&nbsp;Jamiu Aladejana","doi":"10.1016/j.jtemin.2024.100134","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100134","url":null,"abstract":"","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"8 ","pages":"Article 100134"},"PeriodicalIF":0.0,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000193/pdfft?md5=f9f81418adbcdbe18748cd67dc532de8&pid=1-s2.0-S2773050624000193-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140649188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concentrations and probable health risks of potentially toxic metals (Pb, Cd and Cr) in some Nigerian lipstick products","authors":"Ogundele L. Tunde ,&nbsp;Ayeku P. Oluwagbemiga ,&nbsp;Oladejo O. Felix","doi":"10.1016/j.jtemin.2024.100142","DOIUrl":"10.1016/j.jtemin.2024.100142","url":null,"abstract":"<div><h3>Background</h3><p>Lipstick is one of the widely used cosmetic items that are produced from both natural and processed materials and they are one of the sources of metals and metalloids released among the users. This study measured concentrations of Pb, Cd and Cr in some brands of Nigerian lipstick products and assessed their probable health risks to the users.</p></div><div><h3>Methods</h3><p>A total of twenty (L1 - L20) brands of lipstick products were purchased from the central cosmetic stores and the samples were prepared, digested and concentrations of Pb, Cd and Cr were determined using Atomic Absorption Spectrometry (AAS). The probable health risk was assessed via average daily dose (ADD) by ingestion route, hazard quotient (HQ), hazard index (HI), cancer risks (CR), and relative intake index (RII).</p></div><div><h3>Results</h3><p>The ranges of concentrations of Pb, Cd and Cr were 5.6 - 25.1, 2.5 - 21.5 and 5.0 - 61.7 μg g⁻¹, respectively. The ranges of ADD values of Pb, Cr and Cd were 1.2 × 10<em>⁻</em>³ - 5.7 × 10<em>⁻</em>³; 1.3 × 10<em>⁻</em>³ - 5.7 × 10<em>⁻</em>³ and 5.1 × 10<em>⁻</em>³ - 1.4 × 10<em>⁻</em>³ µg day<em>⁻</em>¹, respectively. Among the samples Cr had HQ values 1.3 to 9.6. The HQ values of Cd for L2, L6, L12 and L14 ranges between 1.1 and 1.5. Then HQ values of Pb for L1 -L20 were 1.0 - 4.1. The HI values of Pb, Cr and Cd in each lipstick brands range from 2.8 to 12.5, indicating a non-carcinogenic health risk. The CR values for Cr and Cd are from 6.6 × 10⁻⁴ to 6.9 × 10⁻⁴ and from 2.0 × 10⁻² to 2.5 × 10⁻², respectively and they were within the acceptable limit value of 1.0 × 10⁻⁴. The RII of Pb, Cd and Cr were 4.50 - 20.1, 2.0 – 19.2 and 1.9 – 23.0 %, respectively.</p></div><div><h3>Conclusion</h3><p>All the health indices indicated non-carcinogenic health risks. The continuous exposure and unintentional ingestion of such lipstick products can pose high risks to the users due to bioaccumulation of Pb, Cd and Cr which may lead to negative health conditions.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"8 ","pages":"Article 100142"},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000272/pdfft?md5=d28f84dc802520c4fd231088752bddd0&pid=1-s2.0-S2773050624000272-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140785788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heavy metals and radionuclides in Islamabad's industrial area: A comprehensive analysis of soil and water pollution, source apportionment and health effects using statistical and geospatial tools","authors":"Mavia Anjum ,&nbsp;Naila Siddique ,&nbsp;Hannan Younis ,&nbsp;Yasir Faiz ,&nbsp;Munib Ahmed Shafique ,&nbsp;Anjum Mahnoor ,&nbsp;Ayesha Sajid ,&nbsp;Muhammad Altaf","doi":"10.1016/j.jtemin.2024.100127","DOIUrl":"10.1016/j.jtemin.2024.100127","url":null,"abstract":"<div><h3>Introduction</h3><p>Heavy metal pollution in industrial areas around the world is a significant problem that is worsening day by day. Heavy and toxic metals are detrimental to human health and ecology in a region. Hence, determining their level and potential is critical to form effective pollution control strategies for reducing the risks associated with them.</p></div><div><h3>Study area</h3><p>Islamabad is the capital city of Pakistan with a dedicated industrial zone.</p></div><div><h3>Purpose</h3><p>This study evaluated the heavy metal pollution levels in the soil and water of Islamabad's industrial area and radionuclides activity in the soil using statistical, geospatial tools as well as their subsequent health and ecological hazards.</p></div><div><h3>Materials and methods</h3><p>Elemental analysis in this study was performed using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES). The radionuclides activity in the soil was quantified using High Purity Germanium Detector (HPGe).</p></div><div><h3>Results</h3><p>The soil of Islamabad's industrial area is highly polluted with heavy and toxic metals. The risk posed by heavy metals to the eco-system was calculated using Ecological risk factor and was found to be above recommended level. Principal component analysis (PCA), Pearson's correlation and inverse distance weighting interpolation (IDW) revealed that the soil near the steel mills, landfill and marble processing plants is extremely polluted with heavy metals. Health hazards from heavy metal exposure through ingestion, inhalation, and dermal contact were also calculated. Cr posed a carcinogenic risk to children via the three exposure pathways with the value being 4 × 10⁻⁴. Natural radioactivity levels for Ra-226, Th-232 and K-40 were found to be 25.96±12.50, 15.84±2.59, 469.48±52.38 Bqkg⁻¹, respectively. Elemental analysis of water samples coupled with geospatial analysis showed that water samples collected near the industrial complexes have elevated levels of Sb. The water quality for irrigation was assessed and the water from Islamabad's industrial area was found to be suitable for irrigation.</p></div><div><h3>Conclusion</h3><p>In conclusion, the soil of Islamabad's industrial area is highly polluted with heavy metals and has lower levels of natural radioactivity. The water near the industries also has elevated levels of some heavy metals.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"8 ","pages":"Article 100127"},"PeriodicalIF":0.0,"publicationDate":"2024-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000120/pdfft?md5=839cd735ee8ae12cdf2d9e729e25283a&pid=1-s2.0-S2773050624000120-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140773694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplementation of critical micro-nutrients in peri‑parturient dairy buffaloes improves lactation performance","authors":"Vikas Jyani ,&nbsp;Vishal Mudgal ,&nbsp;Meenakshi Gupta ,&nbsp;Anurag Bharadwaj","doi":"10.1016/j.jtemin.2024.100136","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100136","url":null,"abstract":"<div><h3>Background</h3><p>The peri‑parturient period is the most vital period of a dairy animal's life and affects its future performance. Dairy animals get exposed to severe metabolic stress during the peri‑parturient period and their stress tolerance capacity during the period remains a key factor to harvest optimum production from these animals without getting exposed to any of peri‑parturient disorders. The study aimed to evaluate the effect of weekly critical micro-nutrient (CMN) supplementation during the periparturient period on the lactation performance of Murrah buffaloes.</p></div><div><h3>Methods</h3><p>Weekly CMN (vitamins E, A, and niacin with minerals Co, Cr, Cu, Se, and Zn) supplementation during the periparturient period (56 days prepartum, till 56 days post-partum) was performed on twenty-two healthy Murrah buffaloes during their advanced stage of gestation following dividing them into two groups of 11 buffaloes in each group, representing control and supplemented (Treatment) groups. Buffaloes were selected and sustained on recommended practices of feeding as per nutrient requirements, except the inclusion of CMN supplement once a week in the treatment group's buffaloes after proper mixing with common concentrate mixture being fed to buffaloes. Weekly milk production recording was carried out with analysis of milk quality parameters, for an initial 10 weeks of the lactation.</p></div><div><h3>Results</h3><p>The treatment helped in improving the milk production record of buffaloes; total milk yield by 18 % and fat-corrected milk by 30 % (<em>P</em> &lt; 0.05). It leads to qualitative improvement as well (percentage of milk fat and protein, <em>P</em> &lt; 0.05).</p></div><div><h3>Conclusion</h3><p>It may be concluded that weekly supplementation of critical micronutrients during the periparturient period helps improve buffalo milk production performance.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"8 ","pages":"Article 100136"},"PeriodicalIF":0.0,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000211/pdfft?md5=cbd5ad4751ee86afb7b08488c7c40bc4&pid=1-s2.0-S2773050624000211-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140638381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biofortification of scent leaf (Ocimum gratissimum L.) with selenium enhances antiinflammatory cytokines and humoral response in Wistar rats","authors":"IniOluwa AyoOluwa Akindoyeni ,&nbsp;Idowu Sunday Oyeleye ,&nbsp;Omodesola Oluwafisayo Ogunruku ,&nbsp;Ganiyu Oboh","doi":"10.1016/j.jtemin.2024.100128","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100128","url":null,"abstract":"<div><h3>Background</h3><p>Dietary selenium (Se) has been shown to influence immunity in both humans and rats. It exerts its health effects via incorporation into selenoproteins involved in both innate and adaptive immunity. It is also involved in the synthesis and activity of the antioxidant enzyme glutathione peroxidase. This study sought to investigate the effect of Se biofortified scent leaves (<em>Ocimum gratissimum</em> L.<em>)</em> on selected immunomodulatory and inflammatory markers in wistar rats.</p></div><div><h3>Methodology</h3><p>Scent leaf plant was cultivated on Se fortified (0–0.1 %) soil. Upon maturity, the leaves were harvested and the Se and phenolic contents, as well as in vitro antioxidant properties were determined. Subsequently, dietary inclusions of the Se biofortified scent leaves were fed to rats. The experimental rats consist of control group fed basal diet, rats fed 2.5 % and 5.0 % dietary inclusions of unfortified scent leaves and rats fed 2.5 % and 5.0 % dietary inclusions of 0.05 % Se-fortified scent leaves. This was carried out for 30 days, after which selected immunomodulatory and inflammatory markers, as well as glutathione peroxidase activity (GPx) were quantified in the serum.</p></div><div><h3>Results</h3><p>The vegetables bioaccumulated Se in the leaves up to 0.93 ± 0.05 mg/100 g d.w. The Se biofortified scent leaves exhibited significantly higher in vitro antioxidant properties, total phenol and flavonoid contents quantitatively and qualitatively. In experimental rats, it was observed that the 0.05 % Se biofortified scent leaves based-diets significantly increased the levels of the anti- inflammatory cytokines (IL-4 and IL-10). Furthermore, there were significant increase in serum Immunoglobulins G and M in rats fed dietary inclusions of the Se biofortified leaves.</p></div><div><h3>Conclusion</h3><p>The study suggests that Se biofortification at optimum level of 0.05 % increased phenolic content in scent leaf and improved rat´s anti-inflammatory and antibodies, hence making the vegetables candidate functional food with potential anti-inflammatory and immune boosting properties.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"8 ","pages":"Article 100128"},"PeriodicalIF":0.0,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000132/pdfft?md5=c20d62e55f4ac7a9339a8e08d9770728&pid=1-s2.0-S2773050624000132-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140638380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heavy metal levels in camel milk and health risk assessment: A global systematic review","authors":"Mohamed Amine Kerdoun ,&nbsp;Rachid Djafer","doi":"10.1016/j.jtemin.2024.100131","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100131","url":null,"abstract":"<div><h3>Introduction</h3><p>This systematic review investigates the potential toxicity of metals and metalloids, including lead (Pb), mercury (Hg), cadmium (Cd), and nickel (Ni), in raw camel milk, with a focus on health risk assessment for human consumption through the calculation of Target Hazard Quotient (THQ) and Carcinogenesis Risk (CR).</p></div><div><h3>Methods</h3><p>From 927 initial articles, we analyzed 20 original articles, comprising 787 samples published between 2000 and 2024.</p></div><div><h3>Results</h3><p>Pb levels ranged from nondetectable to 1.560 mg.kg⁻¹, while Cd levels ranged from 0.0008 to 0.800 mg.kg⁻¹. Egypt and Saudi Arabia reported the highest levels of Pb, Ni, and Cd. Pb concentrations in milk exceeded the <em>Codex Alimentarius</em> recommended limit (0.020 mg.kg⁻¹) in 10 out of 18 studies. Overall, Pb and Cd exposure through milk consumption appeared safe for humans, although THQ values exceeded 1 in two Pb studies out of 18 and in one Cd study out of 16.</p></div><div><h3>Conclusion</h3><p>This study contributes to establishing an international database on toxic metal levels in camel milk, informing strategies for managing metal-related risks in milk consumption.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"8 ","pages":"Article 100131"},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000168/pdfft?md5=8b6ebf187b660c4f526b626a1bde9e08&pid=1-s2.0-S2773050624000168-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140605858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A modification of the dimethylglyoxime method for Nickel determination: Application in bioremediation processes","authors":"Micaela B. Gómez Jousse ,&nbsp;Gisela Ferraro ,&nbsp;Federico J. Pomiro ,&nbsp;Daniel M. Pasquevich ,&nbsp;Carolina Bagnato","doi":"10.1016/j.jtemin.2024.100130","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100130","url":null,"abstract":"<div><h3>Background</h3><p>Environmental contamination with nickel is increasing due to the discharge of industrial effluents and other anthropogenic activities. Therefore, the improvement of methods for monitoring nickel concentration is of great value. The dimethylglyoxime (DMG) method is used to determine the nickel concentration in aqueous solutions. This method requires the oxidation of Ni(II) to Ni(IV) by bromine water before adding DMG, which is necessary to complete color development. The original method uses more than 50 mL of final reagent volume per sample. In this study, a volume reduction of the DMG method was performed.</p></div><div><h3>Results</h3><p>A volume reduction of 1 mL per sample was successfully achieved for the DMG method. The working range was 0 - 10 mg Ni(II) L⁻¹. The specified limits of detection and quantification (LOQ and LOD) were 1.18 and 0.41 mg L⁻¹ respectively. A comparative analysis with atomic absorption spectroscopy (AAS) showed no significant differences between both methods for nickel determination. The modified DMG method was effective for the measurement of nickel in experimental samples from a bioremediation assay.</p></div><div><h3>Conclusion</h3><p>The modified DMG method offers considerable advantages. The modified method reduces the volume of reagents used from 50 mL to just 1 mL. The requirement of smaller volume of each reagent is economically favorable, and consequently the amount of passive waste generated is reduced. It is easily reproducible in a laboratory with access to a spectrophotometer and simple reagents. In addition, the possibility to measure samples from bioremediation assays is an advantage.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"8 ","pages":"Article 100130"},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000156/pdfft?md5=e97edce39b1702ef2e688644589154b6&pid=1-s2.0-S2773050624000156-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140631454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of titanium and cobalt urinary release from dental implants by ICP-MS: A case-control study","authors":"Hadil Gribi ,&nbsp;Aya Guenfoud ,&nbsp;Anissa Zergui ,&nbsp;Mokhtar Eddine Djouad","doi":"10.1016/j.jtemin.2024.100126","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100126","url":null,"abstract":"<div><h3>Introduction</h3><p>Dental implants are medical devices designed to replace missing teeth. They are usually made of titanium and cobalt. The present study aimed to evaluate the systematic release of cobalt and titanium in patients with dental implants.</p></div><div><h3>Materials and methods</h3><p>The present case-control study was conducted in dentistry establishments of the region of Chlef and included 24 patients with dental implants (group P) and 24 control subjects (group C). Titanium and cobalt urinary evels were quantified using Inductively Coupled Plasma Mass Spectrometry. The Shapiro–Wilk and Mann-whitney statistical tests were performed using R software.</p></div><div><h3>Results</h3><p>Assessed levels ranged from 0.001 to 0.025 and 0.020–3.900 ug.<em>g</em> ⁻ ¹ of creatinine for titanium and cobalt respectively. No statistically significant differences in titanium and cobalt urinary concentrations were found between the Group P and C (<em>p</em> = 0.521 and <em>p</em> = 0.577 for titanium and cobalt respectively). No statistically significant difference in titanium urinary levels was found between the smokers and non-smokers (<em>p</em> = 0.137). However, a statistically significant difference in cobalt urinary levels was found between the smokers and non-smokers (<em>p</em> = 0.002). In addition, a statistically significant difference in titanium and cobalt urinary levels was found between the subjects with and without orthopaedic implant (<em>p</em> = 0.001).</p></div><div><h3>Conclusion</h3><p>The results revealed that there was no significant release of titanium and cobalt through dental implants in the studied population. Further studies with multidisciplinary approach, long-term follow-up and larger sample are required to evaluate other metals release from dental and orthopaedic implants.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"8 ","pages":"Article 100126"},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000119/pdfft?md5=0153d19456a6b0fb15bc4f6065d31b34&pid=1-s2.0-S2773050624000119-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140605859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Necroptosis in aluminum-induced neural cells and animal models of Alzheimer's disease","authors":"Qinli Zhang ,&nbsp;Qiao Niu","doi":"10.1016/j.jtemin.2024.100125","DOIUrl":"https://doi.org/10.1016/j.jtemin.2024.100125","url":null,"abstract":"<div><h3>Introduction</h3><p>Progressive neural cell loss is a pathological hallmark of Alzheimer's disease (AD). Environmental factors should be taken into consideration due to their epigenetic link to AD, and also because most of the causal environmental factors are preventable. Aluminum (Al) as a common risk environmental factor has been reported to be related to AD. Nonetheless, the nature, time duration, and molecular mechanism of neural cell death in Al-induced AD remain poorly understood. The present article reviews the role of necroptosis, as a novel cell death pathway, in Al-induced AD models in vitro and in vivo.</p></div><div><h3>Methods</h3><p>In the present review, Al-induced necroptosis is summarized in terms of neural cell death and AD animal models induced by Al compounds. Furthermore, a major role of necroptosis in AD is highlighted by comparing studies of apoptosis and autophagy in Al-induced neural cell death and AD animal models.</p></div><div><h3>Results</h3><p>Current research on Al-induced necroptosis has been summarized in Al-treated neural cells and animal AD models. Treatment with Necrostatin-1 (Nec-1) as its specific inhibitor could down-regulate expression of cell death and necroptosis-related proteins; finally, AD-related expression of the signal pathway declined accordingly. The results consistently implied that Al could induce necroptosis, and that Nec-1 could suppress neural cell death pathways not only in Al-induced necroptosis but also in apoptosis and autophagy. Compared with the inhibitors of apoptosis and autophagy, the effects of Nec-1 were more prominent. It indicated that necroptosis is a dominant cell death pathway in Al-treated neural cells and animal models.</p></div><div><h3>Conclusion</h3><p>Based on the relative literature, it has been suggested that necroptosis is involved in the process of Al-induced AD. It implies that Nec-1 represents a promising anti-Alzheimer's approach and has potential theoretical value in environmental factor Al-induced AD neuropathologies.</p></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"8 ","pages":"Article 100125"},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773050624000107/pdfft?md5=0ae3285a4c7ba8004f245616186c7e21&pid=1-s2.0-S2773050624000107-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140550787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}