Journal of the Society for Cardiovascular Angiography & Interventions最新文献

{"title":"The Right Moment to Unload: Preventive Single Inflow Cannula LAVA-ECMO and the Timing of Left Ventricular Decompression in Cardiogenic Shock","authors":"Ahmad Jabri MD, Gennaro Giustino MD, Pedro A. Villablanca MD","doi":"10.1016/j.jscai.2026.105680","DOIUrl":"10.1016/j.jscai.2026.105680","url":null,"abstract":"","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105680"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Left Atrial Appendage Occlusion Versus Oral Anticoagulation in Atrial Fibrillation: A Systematic Review and Bayesian Meta-analysis","authors":"Amar Rai MBBS,&nbsp;Abhinav Kandala BSc,&nbsp;Harroop Bola MBBS,&nbsp;James Schurr MD, PharmD,&nbsp;Mandeep Singh MD,&nbsp;Yousif Ahmad MD,&nbsp;Alexander Fanaroff MD, MHS,&nbsp;Ray Hu MD, MTR,&nbsp;Nitin Malik MD,&nbsp;David S. Frankel MD,&nbsp;Timothy Markman MD,&nbsp;Saman Nazarian MD, PhD,&nbsp;Jay Giri MD, MPH,&nbsp;Tayyab Shah MD,&nbsp;Ashwin Nathan MD, MSHP","doi":"10.1016/j.jscai.2026.105625","DOIUrl":"10.1016/j.jscai.2026.105625","url":null,"abstract":"<div><h3>Background</h3><div>Conflicting randomized trial results have generated uncertainty regarding percutaneous left atrial appendage occlusion (LAAO) vs oral anticoagulation (OAC) for stroke prevention in atrial fibrillation (AF). Thus, the objective of this study is to estimate the posterior probability that LAAO confers clinically meaningful excess ischemic stroke risk relative to OAC.</div></div><div><h3>Methods</h3><div>A Bayesian hierarchical meta-analysis was performed of RCT comparing LAAO with OAC in nonvalvular AF. The primary outcome was ischemic stroke, analyzed using Bayesian random-effects Poisson regression under a vague (primary), skeptical, and enthusiastic prior specification.</div></div><div><h3>Results</h3><div>Six RCT (7004 patients, +18,000 patient-years) were included. Ischemic stroke incidence rate ratio (IRR) was 1.34 (95% credible interval [CrI], 0.91-1.97; <em>P</em> [IRR &gt; 1.0] = 94%). The probability of exceeding 0.5 and 1.0 excess events/100 patient-years was 12% and 0.5%, respectively. The effect on any-stroke was smaller (IRR, 1.09; 95% CrI, 0.76-1.56; <em>P</em> [IRR &gt; 1.0] = 70%; <em>P</em> [absolute rate difference &gt;0.5%/y] = 4.7%), because of a reduction in hemorrhagic stroke (IRR, 0.55; 95% CrI, 0.23-1.18; <em>P</em> [IRR &lt; 1.0] = 94.5%). The decrease in hemorrhagic stroke was attenuated among trials using direct oral anticoagulants for medical management (IRR, 0.80; 95% CrI, 0.33-1.75).</div></div><div><h3>Conclusions</h3><div>In AF, there is a high posterior probability that LAAO is associated with a higher rate of any-stroke, driven by an increase in ischemic stroke relative to OAC. However, the 95% CrI for ischemic stroke crossed unity, and the estimated absolute excess is small. This possible excess must be weighed against a substantial reduction in the risk of hemorrhagic stroke.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105625"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Making the Case for Continuous Quality Improvement in Percutaneous Coronary Intervention","authors":"Karan Vasireddi MBBS,&nbsp;Derek Antoku MD,&nbsp;Arnold H. Seto MD, MPA","doi":"10.1016/j.jscai.2026.105632","DOIUrl":"10.1016/j.jscai.2026.105632","url":null,"abstract":"","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105632"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Versus Delayed Endovascular Revascularization: Implications for Limb Salvage and Survival After Transmetatarsal Amputation","authors":"Ashkan Yahyavi MD,&nbsp;Leen Hussein MD,&nbsp;Zakarias H. Shishehbor,&nbsp;Yara Shatnawi MD,&nbsp;Maedeh Zokaei Nikoo MD,&nbsp;Mehdi H. Shishehbor DO, MPH, PhD","doi":"10.1016/j.jscai.2026.105623","DOIUrl":"10.1016/j.jscai.2026.105623","url":null,"abstract":"<div><h3>Background</h3><div>Healing after transmetatarsal amputation (TMA) depends on adequate tissue perfusion. Revascularization prior to minor amputation improves amputation-free survival, limb preservation, and wound healing in patients with ischemic wounds. However, the optimal interval between revascularization and amputation remains unclear.</div></div><div><h3>Methods</h3><div>The TriNetX real-world clinical data platform was used to identify patients with chronic limb-threatening ischemia (CLTI) who underwent endovascular revascularization followed by TMA. Patients were categorized into early TMA (≤7 days after revascularization) and late TMA (8-30 days). Propensity score matching was performed using demographics, comorbidities, laboratory values, and concurrent therapies. Major amputation and all-cause mortality at 6 months and 1 year were evaluated using Cox proportional hazards models. Kaplan–Meier curves and log-rank tests were used for time-to-event analyses.</div></div><div><h3>Results</h3><div>Among 700 patients with CLTI treated with revascularization before TMA, 508 underwent early TMA and 192 underwent late TMA. After matching, 185 patients remained in each group (96.3% match rate). The mean age was 66.9 ± 10.9 years, 78.1% were male, and mean follow-up was 237.2 days. At 6 months, major amputation (hazard ratio [HR], 0.87; 95% CI, 0.51-1.46; <em>P</em> =.597) and all-cause mortality (HR, 0.74; 95% CI, 0.45-1.20; <em>P</em> = .220) did not differ between groups. At 1-year, major amputation (HR, 0.87; 95% CI, 0.52-1.45; <em>P</em> = .599) and mortality (HR, 0.73; 95% CI, 0.46-1.14; <em>P</em> = .164) also remained similar. A composite endpoint of major amputation or all-cause mortality was also similar between groups (HR, 0.995; 95% CI, 0.694-1.425; <em>P</em> = .978).</div></div><div><h3>Conclusion</h3><div>Among patients with CLTI undergoing endovascular therapy and subsequent TMA, early (≤7 days) vs late (8-30 days) amputation timing did not significantly affect major amputation or survival outcomes.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105623"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left Anterior Descending Coronary Artery Compression After Harmony Transcatheter Pulmonary Valve Implantation","authors":"Ka-Chun Un MBBS,&nbsp;Chun-Ka Wong MBBS,&nbsp;Tomohito Kogure MD,&nbsp;Hay-Son Chen MBBS","doi":"10.1016/j.jscai.2026.105630","DOIUrl":"10.1016/j.jscai.2026.105630","url":null,"abstract":"","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105630"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Efficacy of Sodium-Glucose Cotransporter-2 Inhibitors After Transcatheter Aortic Valve Replacement in Patients With Diabetes: A Global Retrospective Study","authors":"Muhammad Hanif MBBS,&nbsp;Waasay H. Khan MBBS,&nbsp;Shiva P. Sah MBBS,&nbsp;Jai S. Nagarajan MBBS,&nbsp;Jenish Bhandari MBBS,&nbsp;Stephen J. Knohl MD,&nbsp;Cynthia C. Taub MD, MBA,&nbsp;Andrew M. Weinberg DO,&nbsp;Ankur Kalra MD, MSc","doi":"10.1016/j.jscai.2026.105561","DOIUrl":"10.1016/j.jscai.2026.105561","url":null,"abstract":"<div><h3>Background</h3><div>Transcatheter aortic valve replacement (TAVR), a standard therapy for aortic stenosis, is preferred for older or high-risk patients. Various complications, including heart failure (HF), resulting in increased mortality, have been reported in the literature. Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are recommended in HF, irrespective of ejection fraction; however, their role in reducing post-TAVR cardiovascular complications remains underexplored. We conducted a retrospective study to evaluate cardiovascular outcomes associated with the use of SGLT2i in post-TAVR patients.</div></div><div><h3>Methods</h3><div>This retrospective cohort was based on a global database of electronic health records of more than 160 million patients. After propensity-score matching, the study population included 9930 post-TAVR diabetic patients divided into 2 cohorts based on their exposure to SGLT2i. Exposure to SGLT2i was defined as exposure after 1 day of TAVR.</div></div><div><h3>Results</h3><div>In this study of 9930 post-TAVR diabetic patients, the primary outcome of major adverse cardiovascular events and secondary outcomes, ie, cardiovascular mortality, ischemic stroke, and HF exacerbation, were significantly reduced in SGLT2i-exposed post-TAVR patients at the 1-month and 1-year follow-up. Hemorrhagic stroke was comparable at the 1-month follow-up; however, it was significantly lower in SGLT2i-exposed cohorts at the 1-year follow-up. The risk of new-onset myocardial infarction was significantly reduced at 1 month; however, it was comparable between the 2 cohorts at the 1-year follow-up. Our study also demonstrated a significant reduction in the risk of end-stage renal disease in the SGLT2i-exposed cohort at the 1-year follow-up. The periprocedural risk of acute kidney injury (within 7 days of TAVR) as well as at the 1-month and 1-year follow-up was significantly lower in the SGLT2i-exposed cohort.</div></div><div><h3>Conclusions</h3><div>In this study, post-TAVR SGLT2i use in diabetic patients was associated with reduced cardiovascular morbidity and mortality for up to 1 year.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105561"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of Surgical Versus Transcatheter Mitral Valve Repair or Replacement in Patients With Myocardial Infarction and Concomitant Mitral Regurgitation: A Retrospective Analysis of Real-World Data","authors":"Judah Rajendran MD,&nbsp;Akiva Rosenzveig MD,&nbsp;Nishitha Vempalli MD,&nbsp;Raina Roy MD,&nbsp;Andrew Boshara MD,&nbsp;Grant Reed MD,&nbsp;Amar Krishnaswamy MD,&nbsp;Deepak L. Bhatt MD, MPH, MBA,&nbsp;Samir R. Kapadia MD","doi":"10.1016/j.jscai.2026.105626","DOIUrl":"10.1016/j.jscai.2026.105626","url":null,"abstract":"","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105626"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitral Transcatheter Edge-to-Edge Repair in a Challenging Anatomy With Deeply Implanted Self-Expanding Valve and Severe Mitral Annular Calcification: A Case Report","authors":"Muhammad Saad MD,&nbsp;Raviteja Guddeti MD,&nbsp;Nadia El-Hangouche MD,&nbsp;Santiago Garcia MD","doi":"10.1016/j.jscai.2026.105571","DOIUrl":"10.1016/j.jscai.2026.105571","url":null,"abstract":"<div><div>Mitral transcatheter edge-to-edge repair (M-TEER) in the setting of prior transcatheter aortic valve replacement (TAVR) and severe mitral annular calcification (MAC) can pose procedural challenges. We describe the case of an 82-year-old woman with prior TAVR (29 mm EVOLUT FX+; Medtronic), P2 flail, and heavy circumferential MAC underwent M-TEER with the PASCAL Ace device (Edwards Lifesciences). This case illustrates that M-TEER can be performed safely and effectively in anatomies complicated by severe MAC and prior TAVR with careful preprocedural planning, intraprocedural imaging, and operator experience.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105571"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Disparities in Diagnostic and Therapeutic Strategies for Myocardial Infarction With Non-obstructive Coronary Arteries: An International Survey","authors":"Zainab Atiyah Dakhil MD, MSc (Oxon),&nbsp;Hasan Ali Farhan MD,&nbsp;Julia Grapsa MD, PhD,&nbsp;Mirvat Alasnag MD","doi":"10.1016/j.jscai.2026.105560","DOIUrl":"10.1016/j.jscai.2026.105560","url":null,"abstract":"<div><h3>Background</h3><div>Myocardial infarction with non-obstructive coronary arteries (MINOCA) requires multimodality evaluation, including cardiac magnetic resonance (CMR), intracoronary (IC) imaging, and coronary function testing (CFT). However, real-world uptake of these guideline-recommended modalities varies widely. We conducted a global survey to characterize practice variation in MINOCA evaluation and management across demographic characteristics, continents, and economic settings.</div></div><div><h3>Methods</h3><div>A 16-item online survey targeting cardiologists and cardiology trainees was distributed globally between August and December 2024. Respondents provided information on demographic characteristics, institutional context, and routine diagnostic and therapeutic strategies for MINOCA. Descriptive statistics, χ² tests, and multiple regression analysis were used to assess associations.</div></div><div><h3>Results</h3><div>A total of 329 cardiology professionals from 6 continents participated (69.6% interventional cardiologists; 45.9% practicing in high-income countries [HIC]). Overall, 64.1% of respondents reported routine statin use and 55.6% reported beta-blocker use in MINOCA management. Advanced diagnostic modalities demonstrated substantial geographic variation. Europe reported the highest use of CMR (80.6%) and CFT (38.9%), whereas IC imaging was most frequently reported in North America (44.1%). Respondents from HIC reported greater routine use of CMR (56.3% vs 31.6%), IC imaging (41.7% vs 28.9%), and CFT (31.1% vs 13.2%) compared with those from lower-income settings (all <em>P</em> &lt; .01). In multivariable analyses, HIC status remained the strongest independent predictor of routine CMR use (odds ratio [OR], 3.95; 95% CI, 2.34-6.68), IC imaging use (OR, 3.01; 95% CI, 1.74-5.20), and CFT use (OR, 2.29; 95% CI, 1.26-4.14). Academic or teaching hospital affiliation was independently associated with higher CMR use (OR, 2.19; 95% CI, 1.07-4.51), while female respondents reported higher odds of CFT use (OR, 1.89; 95% CI, 1.01-3.54).</div></div><div><h3>Conclusions</h3><div>Significant global disparities exist in the diagnostic evaluation of MINOCA. After adjustment, economic context emerged as the most consistent determinant of advanced diagnostic modality use. These findings highlight persistent structural barriers to the implementation of guideline-recommended MINOCA evaluation and underscore the need for strategies that expand access to advanced diagnostics and promote standardized evaluation pathways across diverse health care settings.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105560"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Calcified Peripheral Artery Disease With the Shockwave Forward Peripheral Intravascular Lithotripsy System: One-Year Outcomes From the FORWARD PAD IDE and Mini S Feasibility Studies","authors":"Andrew Holden MD,&nbsp;John D. Corl MD,&nbsp;Sameh Sayfo MD,&nbsp;Bibombe P. Mwipatayi MD,&nbsp;Manar Khashram MD,&nbsp;Nicolas W. Shammas MD, MS,&nbsp;Anderson Mehrle MD,&nbsp;Anvar Babaev MD,&nbsp;Peter A. Soukas MD,&nbsp;Richard Pin MD,&nbsp;Padma Seethamraju MS,&nbsp;Nick E.J. West MD,&nbsp;Daniel Clair MD","doi":"10.1016/j.jscai.2026.105579","DOIUrl":"10.1016/j.jscai.2026.105579","url":null,"abstract":"","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105579"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}