Samuel Horr MD, Orestis Pappas MD, Ripal T. Gandhi MD, Keith Pereira MD, Jay Giri MD, MPH, Sameer J. Khandhar MD, Ezana M. Azene MD, PhD, Joseph Campbell MD, Jonathan Belsey MBBS, Rick Wat PhD, Jarrod Collins PhD, Wissam A. Jaber MD, Carin F. Gonsalves MD, Stefan Stortecky MD, MPH
{"title":"Cost-Effectiveness of Large-Bore Mechanical Thrombectomy Versus Catheter-Directed Thrombolysis for Intermediate-Risk Pulmonary Embolism: A PEERLESS Randomized Controlled Trial Post Hoc Analysis","authors":"Samuel Horr MD, Orestis Pappas MD, Ripal T. Gandhi MD, Keith Pereira MD, Jay Giri MD, MPH, Sameer J. Khandhar MD, Ezana M. Azene MD, PhD, Joseph Campbell MD, Jonathan Belsey MBBS, Rick Wat PhD, Jarrod Collins PhD, Wissam A. Jaber MD, Carin F. Gonsalves MD, Stefan Stortecky MD, MPH","doi":"10.1016/j.jscai.2026.105578","DOIUrl":"10.1016/j.jscai.2026.105578","url":null,"abstract":"<div><h3>Background</h3><div>This study evaluates the cost-effectiveness of large-bore mechanical thrombectomy (LBMT) compared with catheter-directed thrombolysis (CDT) for the treatment of intermediate-risk pulmonary embolism (PE).</div></div><div><h3>Methods</h3><div>A combined decision tree and Markov model was developed to estimate lifetime health care costs, quality-adjusted life years (QALY), and net monetary benefit from the perspective of the United States health care system. Event probabilities during PE management were derived from the PEERLESS randomized controlled trial. Resource utilization, costs, and long-term event probabilities were established from published literature. Scenario analyses and probabilistic sensitivity analyses were performed to characterize uncertainty.</div></div><div><h3>Results</h3><div>In the base case analysis, LBMT was cost-saving to CDT (ie, lower costs and higher QALY), with a net monetary benefit of $5850 for the willingness-to-pay threshold of $120,000/QALY for LBMT when compared to CDT. In the PE management phase, LBMT yielded a net $4755 cost-saving and 0.009 QALY gained per patient vs CDT, driven in large part by reduced intensive care unit utilization (–$6454), shorter hospital stay (–$2217), avoided thrombolytic costs (–$4068), and fewer 30-day readmissions (–$1134). The long-term care phase yielded a total of $32,012 additional costs per patient over the lifetime with no incremental difference in costs or QALY between groups. These additional costs were driven by venous thromboembolism–related death ($12,377), chronic thromboembolic pulmonary hypertension diagnosis and treatment ($8080), postacute anticoagulation management ($4512), and recurrent venous thromboembolism ($3289). LBMT remained cost-saving across scenarios evaluating CDT cost assumptions and device-specific chronic thromboembolic pulmonary hypertension rates. Probabilistic sensitivity analyses confirmed the robustness of these findings across multiple parameter ranges.</div></div><div><h3>Conclusions</h3><div>Intervention with LBMT in intermediate-risk PE patients in the United States is economically attractive when compared with CDT, resulting in reduced costs and marginally improved patient benefit.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105578"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aymen Ahmed MBBS, Muteia Shakoor MBBS, Usama Hussain Kamal MBBS, Hiba Sohail MBBS, Muhammad Hasnain Mankani MBBS, Vikash Jaiswal MD, Najam Us Saqib MD, Nso Nso MD, MPH, Arman Qamar MD, MPH, Mark J. Ricciardi MD
{"title":"Trends and Disparities in Aortic Stenosis–Related Mortality Among Adults Aged ≥65 Years in the United States From 1999 to 2024","authors":"Aymen Ahmed MBBS, Muteia Shakoor MBBS, Usama Hussain Kamal MBBS, Hiba Sohail MBBS, Muhammad Hasnain Mankani MBBS, Vikash Jaiswal MD, Najam Us Saqib MD, Nso Nso MD, MPH, Arman Qamar MD, MPH, Mark J. Ricciardi MD","doi":"10.1016/j.jscai.2026.105573","DOIUrl":"10.1016/j.jscai.2026.105573","url":null,"abstract":"<div><h3>Background</h3><div>Aortic stenosis (AS) remains a leading cause of cardiovascular death, yet temporal mortality trends specifically among older adults remain poorly characterized. This study analyzed trends and disparities in AS-related mortality among older adults in the United States from 1999 to 2024.</div></div><div><h3>Methods</h3><div>Using the CDC WONDER database, we analyzed AS-related deaths among adults aged ≥65 years. Age-adjusted mortality rates (AAMR) and average annual percent change (AAPC) were calculated across demographic and geographic subgroups.</div></div><div><h3>Results</h3><div>A total of 637,178 deaths were recorded. The overall AAMR for AS-related mortality decreased significantly from 1999 (55.74) to 2024 (52.46) (AAPC, –0.23; <em>P</em> =.004). Although rates rose from 2018 to 2021, a significant decline followed through 2024 (annual percent change, –2.40). Men had consistently higher AAMR than women; mortality remained stable in men (AAPC, –0.06; <em>P</em> = .33), but declined among women (AAPC, –0.35; <em>P</em> =.002). AS-related mortality decreased among patients aged 75 to 84 years, but increased in those ≥85 years (AAPC, 0.28), who had the highest AAMR throughout. Mortality declined in all census regions except for the Midwest, reaching the highest AAMR in 2024 (60.91). Nonmetropolitan areas saw increasing trends, whereas metropolitan areas saw declines. AAMR remained highest among non-Hispanic (NH) White individuals; however, significant decreases were observed in Hispanic/Latino and NH Asian/Pacific Islander populations.</div></div><div><h3>Conclusions</h3><div>Aortic stenosis–related mortality declined modestly among older adults from 1999 to 2024. However, notable demographic and regional disparities persisted, including higher mortality in men, NH White individuals, older adults ≥85 years, and residents of nonmetropolitan regions and the Midwest. Further investigation and targeted interventions are needed to improve outcomes.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105573"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark J. Zorman BM, BCh, Smitha Narayana Gowda MBBS, Ratnasari Padang MBBS, PhD, Jeremy J. Thaden MD, Mayra Guerrero MD, Mackram F. Eleid MD
{"title":"Transcatheter Edge-to-Edge Repair for Mitral Valve Systolic Anterior Motion in Complex Left Ventricular Outflow Tract Phenotypes: A Case Series","authors":"Mark J. Zorman BM, BCh, Smitha Narayana Gowda MBBS, Ratnasari Padang MBBS, PhD, Jeremy J. Thaden MD, Mayra Guerrero MD, Mackram F. Eleid MD","doi":"10.1016/j.jscai.2026.105622","DOIUrl":"10.1016/j.jscai.2026.105622","url":null,"abstract":"<div><div>Dynamic left ventricular outflow tract obstruction due to systolic anterior motion of the mitral valve can arise across diverse anatomic substrates. We report 5 consecutive patients with systolic anterior motion–mediated left ventricular outflow tract obstruction treated with the PASCAL Ace (Edwards Lifesciences) device at a single center. Technical success, mitral regurgitation reduction to ≤2+, relief of left ventricular outflow tract obstruction, and symptomatic improvement to New York Heart Association class I to II were achieved in all patients, without clinically significant mitral stenosis.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105622"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ravi Thakker MD, Adnan Khalif MD, Ying Xu, Seth Bilazarian MD, Dana Bentley BA, J. Dawn Abbott MD, Mario Iannaccone MD, Jason Wollmuth MD, William O’Neill MD, Alexander G. Truesdell MD, Hady Lichaa MD, Mir Babar Basir DO
{"title":"Optimal Sheath for Single-Access Percutaneous Coronary Intervention With Impella CP Hemodynamic Support","authors":"Ravi Thakker MD, Adnan Khalif MD, Ying Xu, Seth Bilazarian MD, Dana Bentley BA, J. Dawn Abbott MD, Mario Iannaccone MD, Jason Wollmuth MD, William O’Neill MD, Alexander G. Truesdell MD, Hady Lichaa MD, Mir Babar Basir DO","doi":"10.1016/j.jscai.2026.105519","DOIUrl":"10.1016/j.jscai.2026.105519","url":null,"abstract":"<div><h3>Background</h3><div>Single-access percutaneous coronary intervention (PCI) with the Impella CP (Abiomed) has increased in prevalence. Despite this, the optimal PCI sheath remains unknown. We characterized the optimal 7F PCI sheath using the single-access technique.</div></div><div><h3>Methods</h3><div>The outer diameter measurement of the sheaths was performed using a Keyence 2-axis laser micrometer (Keyence). The force needed to insert the sheath and the torqueability of the guide catheter were assessed using the Mark-10 M5i Advanced Digital Force/Torque Indicator (Mark-10 Corporation) on a simulated single-access setting in a simulated skin pad. The sample size was determined to be 5 sheaths for each test.</div></div><div><h3>Results</h3><div>The BRITE TIP 11 cm (Cordis), BRITE TIP 35 cm (Cordis), and Destination sheath (Terumo) had the largest outer diameters; the Prelude IDeal (Merit Medical) and Terumo Glidesheath (Terumo) had the smallest outer diameters. The Glidesheath was easiest for insertion/removal, followed by the Prelude IDeal and Impella Low Profile (LP) Companion sheath (Abiomed). The Impella LP Companion, Prelude Roadster (Merit Medical), and Destination sheaths allowed for the best torqueability and lowest force to remove the guide catheter. The longer Impella LP Companion sheath did not impact torqueability, but the removal force increased by 50% compared with the shorter Impella LP Companion sheath.</div></div><div><h3>Conclusion</h3><div>The Impella LP Companion sheath demonstrated the best torqueability and least effort in advancing the guide catheters, while the Prelude Roadster and Destination also performed well on these metrics. The Prelude IDeal and Glidesheath were good options for single-access because of their smaller outer diameters and hydrophilic coating and were easiest for insertion/removal through the 14F LP sheath.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105519"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cover","authors":"","doi":"10.1016/S2772-9303(26)01465-1","DOIUrl":"10.1016/S2772-9303(26)01465-1","url":null,"abstract":"","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105718"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahmoud Balata MD, PhD, Ahmed Samy Badran MD, Mohamed Ibrahim Gbreel MD, Marwa Hassan MD, Islam Ebeid MD, Abdelhakim A. Abdelrahman MD, Daniel Robinson MD, Jonas Bodanowitz MD, Stephan Valenta MD, Christin Valenta MD, Plamen Kochev MD, Hüseyin Ince MD, PhD, Jasmin Ortak MD, PhD
{"title":"Routine Versus Deferred Percutaneous Coronary Intervention in Patients Undergoing Transcatheter Aortic Valve Replacement: A Meta-analysis With Reconstructed Individual Patient Data","authors":"Mahmoud Balata MD, PhD, Ahmed Samy Badran MD, Mohamed Ibrahim Gbreel MD, Marwa Hassan MD, Islam Ebeid MD, Abdelhakim A. Abdelrahman MD, Daniel Robinson MD, Jonas Bodanowitz MD, Stephan Valenta MD, Christin Valenta MD, Plamen Kochev MD, Hüseyin Ince MD, PhD, Jasmin Ortak MD, PhD","doi":"10.1016/j.jscai.2026.105566","DOIUrl":"10.1016/j.jscai.2026.105566","url":null,"abstract":"<div><h3>Background</h3><div>The optimal management of concomitant coronary artery disease in patients undergoing transcatheter aortic valve replacement (TAVR) remains controversial. Whether routine percutaneous coronary intervention (PCI) before TAVR provides clinical benefit compared to a strategy of deferral is unclear.</div></div><div><h3>Methods</h3><div>We performed a meta-analysis of randomized controlled trials (RCT) comparing routine PCI before TAVR with a strategy of PCI deferral. The primary end points were a composite of major adverse cardiovascular and cerebrovascular events (MACCE) and all-cause mortality. Secondary end points included myocardial infarction, stroke, revascularization, and major bleeding. We applied a random-effects model to calculate hazard ratios (HR) and 95% CI. We also performed a pooled time-to-event analysis using reconstructed individual patient data.</div></div><div><h3>Results</h3><div>We included 3 RCT (ACTIVATION, NOTION-3, and PRO-TAVI) comprising a total of 1156 patients. The pooled cohort had a median age exceeding 81 years and exhibited low anatomic coronary complexity (median SYNTAX score ≤10). Routine PCI did not significantly reduce the risk of MACCE (HR, 0.84; 95% CI, 0.62-1.13; <em>P</em> = .25) or all-cause mortality (HR, 0.88; 95% CI, 0.67-1.17; <em>P</em> = .38). Pooled Kaplan-Meier analysis confirmed no difference in all-cause mortality over 48 months (HR, 0.89; 95% CI, 0.68-1.17; <em>P</em> = .41). Although routine PCI was associated with a significant reduction in any revascularization (HR, 0.24; 95% CI, 0.06-0.89; <em>P</em> = .03) and urgent revascularization (HR, 0.33; 95% CI, 0.12-0.87; <em>P</em> = .02), it was associated with increased bleeding events (HR, 1.96; 95% CI, 1.28-3.00; <em>P</em> < .01). No significant differences were observed regarding myocardial infarction or stroke.</div></div><div><h3>Conclusions</h3><div>Routine PCI before TAVR did not reduce mortality or MACCE compared to a deferral strategy. Although routine PCI lowered the risk of subsequent urgent revascularization, it significantly increased the risk of major bleeding.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105566"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steve Kibuom Lee MD, KaChon Lei MD, Malek Al-Hawwas MD, William Aimar Rollefson MD
{"title":"Interrupted Inferior Vena Cava With Azygos Continuation—A Procedural Challenge During Transcatheter Aortic Valve Replacement: A Case Report","authors":"Steve Kibuom Lee MD, KaChon Lei MD, Malek Al-Hawwas MD, William Aimar Rollefson MD","doi":"10.1016/j.jscai.2026.105563","DOIUrl":"10.1016/j.jscai.2026.105563","url":null,"abstract":"<div><div>Interrupted inferior vena cava with azygos continuation is a rare congenital venous anomaly characterized by the absence of the hepatic segment of the inferior vena cava, with venous return from the lower extremities redirected through a dilated azygos vein into the superior vena cava. Although typically clinically silent, this anomaly can pose significant challenges during transcatheter procedures requiring femoral venous access. We describe a case of interrupted inferior vena cava with azygos continuation that was incidentally discovered during transcatheter aortic valve replacement after difficulty advancing a temporary transvenous pacemaker via the femoral venous approach.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105563"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
William E. Camilleri MD, Eleni Ntantou MD, Alexandr Valentijn Kloosterman, Joost Daemen MD, PhD, Jeroen Wilschut MD, Isabella Kardys MD, PhD, Rutger Jan Nuis MD, PhD, Roberto Diletti MD, PhD, Karim Mahmoud MD, PhD, Nicolas M. Van Mieghem MD, PhD, Wijnand K. Den Dekker MD, PhD
{"title":"Ostial vs Left Main Crossover Stenting in Isolated Ostial Left Anterior Descending Stenosis: A Single-Center Retrospective Cohort Study","authors":"William E. Camilleri MD, Eleni Ntantou MD, Alexandr Valentijn Kloosterman, Joost Daemen MD, PhD, Jeroen Wilschut MD, Isabella Kardys MD, PhD, Rutger Jan Nuis MD, PhD, Roberto Diletti MD, PhD, Karim Mahmoud MD, PhD, Nicolas M. Van Mieghem MD, PhD, Wijnand K. Den Dekker MD, PhD","doi":"10.1016/j.jscai.2026.105526","DOIUrl":"10.1016/j.jscai.2026.105526","url":null,"abstract":"<div><h3>Background</h3><div>Limited data exist on the optimal stenting strategy for isolated ostial left anterior descending coronary artery (LAD) lesions. The aim of this study was to compare the outcomes in patients who had a significant isolated ostial LAD stenosis treated with either left main crossover stenting (LMCS) or focal ostial LAD stenting (FO-LAD).</div></div><div><h3>Methods</h3><div>The primary end point of the study was target lesion failure (TLF), a composite of target lesion revascularization, target vessel myocardial infarction, and cardiac death at 2 years. Secondary end points included the individual components of the primary outcome. Additional secondary outcomes included major adverse cardiovascular events, which are a composite of all-cause mortality, myocardial infarction, cerebrovascular accident, and any unplanned revascularization.</div></div><div><h3>Results</h3><div>A total of 522 patients were included in this study, of whom 382 underwent FO-LAD stenting and 140 underwent LMCS. The primary outcome occurred in 32 patients (22.9%) in the LMCS and in 44 patients (11.5%) in the FO-LAD group at a median follow-up of 730 days (IQR, 451-730). LMCS was associated with a higher risk of TLF compared with FO-LAD stenting (adjusted HR, 1.86; 95% CI, 1.16-2.98; <em>P</em> = .01).</div><div>With regard to secondary outcomes, LMCS was associated with more major adverse cardiovascular events (31.4% vs 15.5%; adjusted HR, 2.11 [1.41-3.17]; <em>P</em> < .001) and cardiac death (17.1% vs 7.9%; adjusted HR, 2.05 [1.19-3.55]; <em>P</em> = .01]. No significant differences were observed for target lesion revascularization and target vessel myocardial infarction.</div></div><div><h3>Conclusions</h3><div>Left main crossover stenting was associated with a higher rate of TLF at a median follow-up of 2 years when compared with FO-LAD stenting in the treatment of patients with significant isolated ostial LAD disease.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105526"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arnav Kumar Singla MD, Basmah Fayaz MD, Christopher Heinrich MD, Samuel Miller BS, John Simpson BS, Samantha Mutai DO, Gilgamish Maloul MD, Malek Lababidi MD, Julie Ahrenholz MS, Weili Zheng MD, Faisal Hasan MD, Hussam S. Suradi MD
{"title":"Impact of a Continuous Quality Improvement Committee on Outcomes for Patients Undergoing Percutaneous Coronary Intervention: A Single-Center Retrospective Cohort Study","authors":"Arnav Kumar Singla MD, Basmah Fayaz MD, Christopher Heinrich MD, Samuel Miller BS, John Simpson BS, Samantha Mutai DO, Gilgamish Maloul MD, Malek Lababidi MD, Julie Ahrenholz MS, Weili Zheng MD, Faisal Hasan MD, Hussam S. Suradi MD","doi":"10.1016/j.jscai.2026.105577","DOIUrl":"10.1016/j.jscai.2026.105577","url":null,"abstract":"<div><h3>Background</h3><div>Continuous quality improvement (CQI) programs aim to enhance procedural safety and efficiency in percutaneous coronary intervention (PCI). This analysis evaluates changes in PCI practice patterns and outcomes after implementation of a multidisciplinary catheterization laboratory CQI committee at a large academic center.</div></div><div><h3>Methods</h3><div>A retrospective cohort study was conducted regarding PCI procedures from January 2018 to June 2024 using National Cardiovascular Data Registry CathPCI data. Outcomes and practice patterns were compared before (pre-CQI: 2018-October 2022) versus after CQI implementation (post-CQI: November 2022-2024). Prespecified primary end points were post-PCI acute kidney injury, periprocedural hemoglobin change, and same-day discharge.</div></div><div><h3>Results</h3><div>Among 2759 PCI cases (1783 pre-CQI; 976 post-CQI), monthly PCI volume increased (30.7-48.2 cases/mo, <em>P</em> < .001). Post-CQI, radial access use increased (33.4%-58.9%, <em>P</em> < .001) and mean contrast volume decreased (188-153 mL, <em>P</em> < .001). Primary outcomes improved post-CQI: acute kidney injury decreased (14.3%-9.7%, <em>P</em> = .01), mean periprocedural hemoglobin change decreased (0.65-0.54 g/dL, <em>P</em> = .004), and same-day discharge increased (13.0%-24.7%, <em>P</em> < .001). Overall complication rates and in-hospital mortality remained stable.</div></div><div><h3>Conclusions</h3><div>Implementation of a catheterization laboratory CQI committee was temporally associated with improved PCI safety and discharge efficiency alongside increased procedural volume and evolving case mix. These findings support CQI-driven approaches to optimize PCI care delivery.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105577"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samia Mazumder MD, Tim Joseph MD, Devraj Sukul MD, Araya Negash DO, Justin Armstrong DO, Lakshmi Rao MD, Najeebullah Bangash MD, Ryan D. Madder MD
{"title":"Evaluation of an Artificial Intelligence and Machine Learning Algorithm to Enhance Angiographic Coronary Visibility in Morbid Obesity: A Retrospective Observational Study","authors":"Samia Mazumder MD, Tim Joseph MD, Devraj Sukul MD, Araya Negash DO, Justin Armstrong DO, Lakshmi Rao MD, Najeebullah Bangash MD, Ryan D. Madder MD","doi":"10.1016/j.jscai.2026.105627","DOIUrl":"10.1016/j.jscai.2026.105627","url":null,"abstract":"","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"5 10","pages":"Article 105627"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149222303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}