Aleksandra B. Gruslova PhD , Drew Nolen MS , Nitesh Katta PhD , Thomas E. Milner PhD , Marc D. Feldman M.D., MSCAI
{"title":"OR3-7 | Fracture Orientation in Intravascular Lithotripsy","authors":"Aleksandra B. Gruslova PhD , Drew Nolen MS , Nitesh Katta PhD , Thomas E. Milner PhD , Marc D. Feldman M.D., MSCAI","doi":"10.1016/j.jscai.2025.102709","DOIUrl":"10.1016/j.jscai.2025.102709","url":null,"abstract":"","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"4 5","pages":"Article 102709"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James Schurr MD, PharmD, Jacob Niculcea BS, Tayyab Shah M.D., Aditya Parikh MD, Juan Ortega-Legaspi MD, PhD, Mauer Biscotti MD, Marisa Cevasco MD, MPH, John Greenwood MD, Joyce Wald D.O.
{"title":"OR3-21 | Microcirculatory Effects of a Full Support Microaxial Flow Pump in Cardiogenic Shock: Preliminary Results of the MICRO-C-SHOCK Study","authors":"James Schurr MD, PharmD, Jacob Niculcea BS, Tayyab Shah M.D., Aditya Parikh MD, Juan Ortega-Legaspi MD, PhD, Mauer Biscotti MD, Marisa Cevasco MD, MPH, John Greenwood MD, Joyce Wald D.O.","doi":"10.1016/j.jscai.2025.102717","DOIUrl":"10.1016/j.jscai.2025.102717","url":null,"abstract":"","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"4 5","pages":"Article 102717"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143894298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A-2 | Associations between Periodontal Disease and Hospitalization Outcomes in ST Elevation Myocardial Infarction: Insights from the United States National Inpatient Sample","authors":"Nadhem Abdallah , Abdilahi Mohamoud MBBS , Momen Alsayed","doi":"10.1016/j.jscai.2025.102752","DOIUrl":"10.1016/j.jscai.2025.102752","url":null,"abstract":"","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"4 5","pages":"Article 102752"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David G. Rizik MD , Robert F. Burke MD , Robert D. Riley MD , Zain Khalpey MD, PhD , Danny S. Eads MD , Charles M. Wojnarski MD, MS , L.T.C. Seth M. Assar MD , Aditya Gupta MD , Rebecca C. Chester MD , James A. Goldstein MD
{"title":"Mitral Transcatheter Edge-to-Edge Repair and Mandatory Mechanical Circulatory Support in Patients With Structural Shock","authors":"David G. Rizik MD , Robert F. Burke MD , Robert D. Riley MD , Zain Khalpey MD, PhD , Danny S. Eads MD , Charles M. Wojnarski MD, MS , L.T.C. Seth M. Assar MD , Aditya Gupta MD , Rebecca C. Chester MD , James A. Goldstein MD","doi":"10.1016/j.jscai.2025.102626","DOIUrl":"10.1016/j.jscai.2025.102626","url":null,"abstract":"<div><h3>Background</h3><div>Mitral regurgitation (MR) may be a cause or contributor to cardiogenic shock (CS). The roles of mitral transcatheter edge-to-edge repair (M-TEER) and mechanical circulatory support (MCS) have not been fully delineated. This prospective registry of patients with significant MR and CS was designed to determine procedural success and survival with M-TEER performed with mandatory MCS.</div></div><div><h3>Methods</h3><div>Over an 8-year period ending August 2024, this single hospital system prospective analysis identified consecutive patients with CS with significant MR. The primary outcome was achieving pre-defined procedural objectives: In aggregate, an absolute >2 Grade MR reduction, normalization of pulmonary venous flow pattern and final mean transvalvular gradient <5 mmHg and 6-month mortality.</div></div><div><h3>Results</h3><div>The cohort included n = 30 patients with acute hemodynamic deterioration (mean age 74.1 + 13.7 years, 63.3% male). Mean Society of Thoracic Surgery score (MV repair) was 13.6% + 14.7%. Clinical profiles included: Chronic progressive shock/Acute shock on chronic CHF (50%), Ruptured mitral valve chordae with leaflet incompetence and intact LVEF (23.3%), Mixed etiology defined as reduced EF and ruptured chordae (13.3%) and Acute myocardial infarction (AMI) induced papillary muscle rupture (13.3%). M-TEER with mandatory MCS was performed in all 30 patients. Procedural objectives were achieved in 25 patients (83.3%). Survival to hospital discharge was 86.6% and at 3-months 80.0%. Overall, 6-month survival was 73.3%.</div></div><div><h3>Conclusions</h3><div>In CS complicated by significant MR, M-TEER with mandatory MCS can be performed with excellent procedural success and is associated with favorable clinical outcomes.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"4 5","pages":"Article 102626"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zeryab A. Khan DO, Cody Carter DO, Jordan Luli DO, Nathan Marzlin MD, Johnathan Hatanelas DO, Lindsay Castle DO, Kevin Stiver MD, Laura Flannery MD, Steven J. Yakubov MD, Carlos Sanchez MD
{"title":"Sealing the Leak: Transcatheter Repair of Anterior Mitral Leaflet Perforation With Amplatzer Vascular Plug 4","authors":"Zeryab A. Khan DO, Cody Carter DO, Jordan Luli DO, Nathan Marzlin MD, Johnathan Hatanelas DO, Lindsay Castle DO, Kevin Stiver MD, Laura Flannery MD, Steven J. Yakubov MD, Carlos Sanchez MD","doi":"10.1016/j.jscai.2025.102634","DOIUrl":"10.1016/j.jscai.2025.102634","url":null,"abstract":"<div><div>We document the first reported use of the Amplatzer Vascular Plug 4 for anterior mitral leaflet perforation repair in a 56-year-old male who had undergone valve-in-valve transcatheter aortic valve replacement. Previously reported cases involving the use of other occluder devices for mitral leaflet perforation repair either required guide catheter or delivery sheath exchanges, arteriovenous wire loop for deployment, or use of mitral transcatheter edge-to-edge repair for leaflet stability. Our case highlights the efficacy of the bilobar-designed Amplatzer Vascular Plug 4 for precise occlusion in anterior mitral leaflet perforation through antegrade-only delivery and safety through the simplification of procedural steps.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"4 5","pages":"Article 102634"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hassan Saleh MD , Ibrahim Khaleel MD , Connor Kerndt DO , Paul Weber DO , Matthew Hollowell MD , Connor McCalmon MD , Theresa Pasion BS , Mohammad Ahmed MD , Mazin Habhab MD , Nolan Rossman MS , Jessi Parker MS , Brian Trethowan MD , Marcel Letourneau DO
{"title":"Outcomes in Patients With Pulmonary Embolism Treated With Mechanical Thrombectomy or Anticoagulation Alone","authors":"Hassan Saleh MD , Ibrahim Khaleel MD , Connor Kerndt DO , Paul Weber DO , Matthew Hollowell MD , Connor McCalmon MD , Theresa Pasion BS , Mohammad Ahmed MD , Mazin Habhab MD , Nolan Rossman MS , Jessi Parker MS , Brian Trethowan MD , Marcel Letourneau DO","doi":"10.1016/j.jscai.2025.102611","DOIUrl":"10.1016/j.jscai.2025.102611","url":null,"abstract":"<div><h3>Background</h3><div>Pulmonary embolism (PE) is a leading cause of cardiovascular death; little data exist on whether mechanical thrombectomy confers a mortality benefit. Using a retrospective review, 311 consecutive patients with PE who underwent aspiration thrombectomy were compared to 309 propensity score–matched patients with PE treated with anticoagulation alone.</div></div><div><h3>Methods</h3><div>Using a retrospective review, we identified 311 consecutive patients with PE who underwent mechanical thrombectomy along with standard of care; we then identified 1841 patients admitted with a primary diagnosis of PE and used propensity score matching to identify 309 patients with similar pulmonary embolism severity index (PESI) scores and variables. We then evaluated 2-year outcomes between the 2 groups.</div></div><div><h3>Results</h3><div>Of the 311 patients treated with thrombectomy, 262 were at elevated risk by the European Society of Cardiology (ESC) stratification, 261 had a positive simplified pulmonary embolism severity index (sPESI) and 208 were of PESI class III or higher. Of the 309 patients treated with anticoagulation alone, 261 had elevated risk by ESC stratification, 257 had a positive sPESI, and 201 were PESI class III or higher. When all patients were evaluated, there was a mortality benefit starting at 30 days in patients undergoing thrombectomy; when patients with metastatic cancer were excluded, the mortality benefit was only seen in higher-risk patients. Low-risk patients with or without right ventricular strain had similar mortality whether managed with thrombectomy or anticoagulation alone, with numerically more significant bleeding, stroke, and recurrent pulmonary emboli.</div></div><div><h3>Conclusions</h3><div>In this single-center, retrospective review, patients with PE who were of ESC high risk and who underwent aspiration thrombectomy with a FlowTriever System (Inari Medical) had a statistically significant reduction in mortality compared to a propensity score–matched group treated with anticoagulation alone; separation in mortality curves continued at 2 years. Our findings also suggest that low-risk patients perform equally well with or without thrombectomy but incur numerically more bleeding events, stroke, and recurrent pulmonary emboli.</div></div>","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"4 5","pages":"Article 102611"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emmanuel Daniel , Karldon Nwaezeapu , Lilian Briggs , Kayode Ogunniyi , Tioluwani Ojo , Mohammed El-Nayir , Yash B. Patel MD , Misha A. Khan MD
{"title":"OR1-9 | Comparative Long-Term Clinical Outcomes of Ticagrelor vs. Prasugrel Following PCI of CTO: A Real-World Analysis from the Trinetx Database","authors":"Emmanuel Daniel , Karldon Nwaezeapu , Lilian Briggs , Kayode Ogunniyi , Tioluwani Ojo , Mohammed El-Nayir , Yash B. Patel MD , Misha A. Khan MD","doi":"10.1016/j.jscai.2025.102660","DOIUrl":"10.1016/j.jscai.2025.102660","url":null,"abstract":"","PeriodicalId":73990,"journal":{"name":"Journal of the Society for Cardiovascular Angiography & Interventions","volume":"4 5","pages":"Article 102660"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143894634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}